Effects of posture on plasma volume and some blood constituents.

abstract：INTRODUCTION:Large granular lymphocyte (LGL) leukaemia is considered a mature T-cell or natural killer (NK) cell neoplasm, characterised by a clonal proliferation of LGL. AIMS:To analyse the characteristics and to establish (if possible) the prognostic parameters of these patients diagnosed in a single centre: Univers...

journal_title：Journal of clinical pathology

authors： Uranga A,González C,Furundarena JR,Robado N,Rey M,Aragon L,Urreta I,Aranbarri A,De Juan MD,Araiz M

更新日期：2021-01-21 00:00:00

abstract：:In a twenty-year period 19 appendicectomy specimens were diagnosed as primary Crohn's disease. This represents 4.9% of the total number of both resection specimens and mucosal biopsies diagnosed as Crohn's disease during that time. This is a review of the main histopathological features found in these appendices and t...

journal_title：Journal of clinical pathology

authors： Allen DC,Biggart JD

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:In primary cutaneous melanoma, the sentinel node (SN) biopsy is an accurate method for the staging of the lymph nodes. Positron emission tomography (PET) has been suggested as a useful alternative. However, the sensitivity of PET may be too low to detect SN metastases, which are often small. AIM:To predict ...

journal_title：Journal of clinical pathology

authors： Mijnhout GS,Hoekstra OS,van Lingen A,van Diest PJ,Adèr HJ,Lammertsma AA,Pijpers R,Meijer S,Teule GJ

更新日期：2003-04-01 00:00:00

abstract：AIM:To determine the frequency of skip lesions in an unselected series of temporal artery biopsies and compare the results with other series. METHODS:The study was a retrospective review of 102 consecutive temporal artery biopsies taken in a five year period (1992-1997) in one large hospital. RESULTS:35 cases (34.3%)...

journal_title：Journal of clinical pathology

authors： Poller DN,van Wyk Q,Jeffrey MJ

更新日期：2000-02-01 00:00:00

abstract：:The only method currently available to perform Neisseria gonorrhoeae antimicrobial susceptibility testing (Ng-AST) requires a viable organism obtained by culture. Reports of in vitro resistance to extended-spectrum cephalosporins, the treatment of choice for gonorrhoea, coupled with increasing gonorrhoea diagnoses is ...

journal_title：Journal of clinical pathology

authors： Jain A,Cole MJ,Planche T,Ison CA

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:EpCAM is an adhesion molecule of the basolateral membranes in a variety of epithelial cells. Over-expression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. AIMS:To assess the prognostic value of EpCAM in urothelial ...

journal_title：Journal of clinical pathology

authors： Brunner A,Prelog M,Verdorfer I,Tzankov A,Mikuz G,Ensinger C

更新日期：2008-03-01 00:00:00

abstract：:In the past decade, cellular immunophenotyping has become a new discipline in diagnostic haematology and immunology, and is invaluable in the rapid diagnosis of leukaemia and monitoring disease progression in human immunodeficiency virus infected individuals. The introduction of bench top flow cytometers has meant tha...

journal_title：Journal of clinical pathology

authors： Reilly JT,Barnett D

更新日期：2001-07-01 00:00:00

abstract：:The morphological classification and diagnosis of bladder neoplasms is summarised, with specific focus on histological typing, grading and staging. Four diagnostic categories are described on the basis of the pattern of growth of the urothelial lesions and tumours (flat, exophytic or papillary, endophytic, and invasiv...

journal_title：Journal of clinical pathology

authors： Montironi R,Mazzucchelli R,Scarpelli M,Lopez-Beltran A,Cheng L

更新日期：2008-01-01 00:00:00

abstract：AIM:To ascertain the views of Scottish hospital laboratory users on aspects of regional and supraregional biochemical services offered by the Institute of Biochemistry at Glasgow Royal Infirmary. METHODS:A questionnaire was circulated asking questions or inviting opinions under various headings, including current patt...

journal_title：Journal of clinical pathology

authors： Murphy MJ,Dryburgh FJ,Shepherd J

更新日期：1994-05-01 00:00:00

abstract：:Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal ep...

journal_title：Journal of clinical pathology

authors： Jenkins D,Stephenson PM,Scott BB

更新日期：1985-03-01 00:00:00

abstract：:The peripheral lymphocytes of 50 cases of human immunodeficiency virus (HIV) infection (13 of acquired immune deficiency syndrome (AIDS), 17 of AIDS related complex (ARC), and 20 healthy carriers) were studied immunoultrastructurally. The prevalence of "tubuloreticular structures" and "tubular confronting cisternae" i...

journal_title：Journal of clinical pathology

authors： Feremans WW,Huygen K,Menu R,Farber CM,de Caluwe JP,van Vooren JP,Marcelis L,Andre L,Brasseur M,Bondue H

更新日期：1988-01-01 00:00:00

abstract：AIMS:To evaluate two detailed step sectioning protocols for sentinel lymph nodes (SLNs). METHODS:After vital dye or combined dye and radiocolloid guided biopsy, SLNs were fixed in formalin and embedded in paraffin wax. In protocol A, SLNs from 123 patients were sectioned in steps of 50-100 micro m, whereas in protocol...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：2002-12-01 00:00:00

abstract：:A rapid technique using a non-radioactive receptor molecule (digoxigenin) for intrahepatic hepatitis B virus (HBV) DNA detection using in situ hybridisation was developed. It can be adapted for use in combination with standard immunohistochemistry for simultaneous detection of both HBV DNA and HBV antigens. The total ...

journal_title：Journal of clinical pathology

authors： Lau JY,Naoumov NV,Alexander GJ,Williams R

更新日期：1991-11-01 00:00:00

abstract：:In a case of atypical mucin-producing bronchial carcinoid in a 40-year-old man covert metastases were present at the time of lobectomy and were revealed at necropsy--a feature highlighting the malignant potential of the atypical carcinoid. ...

journal_title：Journal of clinical pathology

authors： Sweeney EC,Cooney T

更新日期：1978-12-01 00:00:00

abstract：AIMS:To investigate the correlation between centrally assessed human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) results and response to treatment of patients with metastatic breast cancer enrolled in a first-line, phase II, open-label, 3-weekly tra...

journal_title：Journal of clinical pathology

authors： Hofmann M,Stoss O,Gaiser T,Kneitz H,Heinmöller P,Gutjahr T,Kaufmann M,Henkel T,Rüschoff J

更新日期：2008-01-01 00:00:00

abstract：:A case of extramedullary myeloblastic transformation of chronic myeloid leukaemia is reported. This was characterised by an unusual clinical and haematological course and showed a unique cytogenetic pattern. ...

journal_title：Journal of clinical pathology

authors： Flanagan NG,Harrison CJ,Harry DS,Ridway JC

更新日期：1985-07-01 00:00:00

abstract：:Splenic pathology was analysed in 73 patients with immune thrombocytopenic purpura who underwent splenectomy for bleeding that had been resistant to adrenocorticosteroids. The mean splenic weight was 100 g. The only notable macroscopic feature was the prominence of Malpighian corpuscles in 15 cases. Microscopic examin...

journal_title：Journal of clinical pathology

authors： Hayes MM,Jacobs P,Wood L,Dent DM

更新日期：1985-09-01 00:00:00

abstract：AIM:We aimed to assess the one step nucleic acid amplification (OSNA) assay as an intraoperative method in comparison with frozen sections (FS) for detection of metastasis in sentinel lymph nodes (SLNs) of breast cancer. METHOD:100 SLNs from patients with breast carcinoma were enrolled within a 3-month period. Alterna...

journal_title：Journal of clinical pathology

authors： Jara-Lazaro AR,Hussain IH,Thike AA,Wong CY,Ho GH,Yong WS,Ong KW,Madhukumar P,Tan BK,Oey CL,Hwang JS,Tan PH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterised by the presence of various laboratory abnormalities but the precise role of laboratory staff in initiating clinical referral and subsequent biopsy is not clear. OBJECTIVE:To examine the impact of laboratory abnormalities in the inv...

journal_title：Journal of clinical pathology

authors： Sinclair D,Spedding A,Young R

更新日期：2006-04-01 00:00:00

abstract：:Late-stage ovarian carcinoma is almost universally fatal. BRCA mutations are associated with an improved outcome and enhanced sensitivity to platinum chemotherapy, yet recurrence and platinum resistance remain a major problem and highly effective regimens following platinum failure do not yet exist. Here we report a r...

journal_title：Journal of clinical pathology

authors： Osher DJ,Kushner YB,Arseneau J,Foulkes WD

更新日期：2011-10-01 00:00:00

abstract：AIMS:The aims of the study were to compare bacterial recovery following storage of sputum samples at 20 degrees C room temperature and 4 degrees C (refrigerated) for 24 h, and to determine the effect of postage on viable bacterial numbers. METHODS:A total of 38 individual sputum samples from clinically stable patients...

journal_title：Journal of clinical pathology

authors： Pye A,Hill SL,Bharadwa P,Stockley RA

更新日期：2008-03-01 00:00:00

abstract：AIM:To analyse whether the mean nuclear area of the 10 largest nuclei (MNA-10), the mitotic activity index (MAI), and Ki-67 immunoquantitative features have additional value to discriminate different grades of T(A,1) transitional cell carcinoma (TCC) of the urinary bladder. MATERIALS/METHODS:One hundred and fifty of 2...

journal_title：Journal of clinical pathology

authors： Bol MG,Baak JP,de Bruin PC,Rep S,Marx W,Bos S,Kisman O

更新日期：2001-11-01 00:00:00

abstract：AIMS:To assess the incidence of nocardia infection over 15 years in a tertiary care hospital. METHODS:Over a 15 year period, Nocardia spp were isolated from 20 patients hospitalised at the Geneva University Hospitals, Switzerland. RESULTS:Sixteen patients had one or more underlying conditions. The median time between...

journal_title：Journal of clinical pathology

authors： Matulionyte R,Rohner P,Uçkay I,Lew D,Garbino J

更新日期：2004-08-01 00:00:00

abstract：:Factor VIII procoagulant activity (VIII:C), factor VIII related antigen (VIIIR:AG), and the von Willebrand factor (VIII:WF) were measured in 19 patients with liver disease (8 cases of alcoholic cirrhosis and 11 with acute viral hepatitis). In both groups of patients the levels of VIII:C, VIIIR:AG, and VIIIR:WF were ab...

journal_title：Journal of clinical pathology

authors： Maisonneuve P,Sultan Y

更新日期：1977-03-01 00:00:00

abstract：AIMS:The incidence of RAS/RAF/PI3KA and TP53 gene mutations in colorectal cancer (CRC) is well established. Less information, however, is available on other components of the CRC genomic landscape, which are potential CRC prognostic/predictive markers. METHODS:Following a previous validation study, ion-semiconductor n...

journal_title：Journal of clinical pathology

authors： Malapelle U,Pisapia P,Sgariglia R,Vigliar E,Biglietto M,Carlomagno C,Giuffrè G,Bellevicine C,Troncone G

更新日期：2016-09-01 00:00:00

abstract：:Specimens from 95 patients attending a venereal diseases clinic were examined for gonococci by three methods--a conventional culture technique using modified Thayer-Martin medium, microscopy of a Gram-stained direct smear, and the Microcult system. For 56% of the specimens the results by all three methods agreed. Assu...

journal_title：Journal of clinical pathology

authors： Williams RJ,Ratnatunga CS,Hamilton-Miller JM,Brumfitt W

更新日期：1978-03-01 00:00:00

abstract：AIMS:To assess the consistency and reproducibility of assessment of c-erbB-2 immunostaining, and to examine some of the problems relating to inter- and intraobserver variability in the documentation of positive staining; to profile the spectrum of cytoplasmic and membranous staining in a wide range of tumour types. ME...

journal_title：Journal of clinical pathology

authors： Kay EW,Walsh CJ,Cassidy M,Curran B,Leader M

更新日期：1994-09-01 00:00:00

abstract：:Nasal biopsy findings in malignant histiocytosis presenting clinically as lethal midline granuloma are characterised by necrosis and infiltration of atypical histiocytic cells with a diffuse positive reaction for non-specific esterase. This cellular character was common to midline malignant reticulosis, and midline ma...

journal_title：Journal of clinical pathology

authors： Aozasa K

更新日期：1982-06-01 00:00:00

abstract：:Four cases of human infection with Achromobacter anitratus, one of which was fatal, are described. They all occurred at one hospital within a period of two months. The bacteriology, antibiotic sensitivity, and pathogenicity of the organisms are discussed. One of the strains was found to differ from the other three. ...

journal_title：Journal of clinical pathology

authors： ASHLEY DJ,KWANTES W

更新日期：1961-11-01 00:00:00

abstract：AIMS:Venous invasion (VI) is a known independent prognostic indicator of recurrence and survival in colorectal cancer. The guidelines of the Royal College of Pathologists (RCPath) state that, in a series of resections, extramural VI should be detected in at least 25% of specimens. However, there is widespread variabili...

journal_title：Journal of clinical pathology

authors： Messenger DE,Driman DK,McLeod RS,Riddell RH,Kirsch R

更新日期：2011-11-01 00:00:00