Biopsy findings in malignant histiocytosis presenting as lethal midline granuloma.

abstract：AIMS:To determine the effect of pregnancy on C4d concentrations and to assess whether C4d remains a useful disease activity marker in the management of connective tissue diseases during pregnancy. METHODS:Plasma C3, C4, and C4d concentrations were measured in 83 women at various stages of normal pregnancy and compared...

journal_title：Journal of clinical pathology

authors： Hopkinson ND,Powell RJ

更新日期：1992-01-01 00:00:00

abstract：:A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosi...

journal_title：Journal of clinical pathology

authors： Hann IM,Evans DI,Marsden HB,Jones PM,Palmer MK

更新日期：1978-04-01 00:00:00

abstract：:A latex enzyme immunoassay (LEIA) for detecting IgG class antibody to rubella virus was compared with the latex agglutination test (LA) and a haemagglutination inhibition assay (HI). Of 243 sera tested, four discrepant results were observed among all three techniques, corresponding to borderline values. Except for one...

journal_title：Journal of clinical pathology

authors： Duverlie G,Roussel C,Driencourt M,Orfila J

更新日期：1990-09-01 00:00:00

abstract：:The clinical features and special investigations in a case of multiple myelomatosis are described. The finding of exfoliated ;myeloma cells' in the urine of this case is thought to be unique, these cells closely resembling the myeloma cells seen in the bone marrow. The necropsy findings indicated that the origin of th...

journal_title：Journal of clinical pathology

authors： PROWSE CM,BLECHER TE

更新日期：1962-03-01 00:00:00

abstract：:As part of a quality assurance programme at the Aga Khan University Medical Centre, Karachi, Pakistan, all hysterectomy specimens were reviewed from January 1986 to December 1989. Adenomyosis was found in 237 of the 419 (56.5%) specimens studied. Of these 237 patients, 232 (97.9%) were parous and 196 (82.8%) were in t...

journal_title：Journal of clinical pathology

authors： Shaikh H,Khan KS

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Coronary heart disease is associated with increased B-type natriuretic peptides (BNPs), and, although controversial, may cause exaggerated exercise-induced BNP secretion. We investigated BNP in relation to reversible myocardial ischaemia. MATERIALS AND METHODS:Serum N-terminal proBNP (NT-proBNP) was measure...

journal_title：Journal of clinical pathology

authors： Chatha K,Alsoud M,Griffiths MJ,Elfatih A,Abozguia K,Horton RC,Dunmore SJ,Gama R

更新日期：2006-11-01 00:00:00

abstract：AIMS:To identify the number and geographical distribution of post mortem examinations performed on HIV infected cadavers; to identify the areas that perform post mortem examinations so that, by invitation and discussion, a national post mortem network could be initiated. METHODS:A nationwide survey of Royal College of...

journal_title：Journal of clinical pathology

authors： Davies J,Everall IP,Lantos PL

更新日期：1993-12-01 00:00:00

abstract：AIMS:(1) To investigate the immunohistochemical expression of the multidrug resistance gene (MDR1) product P-glycoprotein in histological samples from 31 hepatocellular carcinomas (HCCs); and (2) to correlate the results with cell proliferation, p53 expression, the disease-free interval, and cumulative patient survival...

journal_title：Journal of clinical pathology

authors： Soini Y,Virkajärvi N,Raunio H,Pääkkö P

更新日期：1996-06-01 00:00:00

abstract：:Structural chromosomal aberrations, in the form of breaks, were found in a significantly higher proportion of bone marrow cells in patients with infective hepatitis than in controls. These anomalies were observed during the first and third weeks after the onset of jaundice but had subsided by the sixth week. Chromosom...

journal_title：Journal of clinical pathology

authors： Matsaniotis N,Kiossoglou K,Maounis F,Anagnostakis D

更新日期：1970-10-01 00:00:00

abstract：:IgD myeloma is a rare disorder with a very poor prognosis. An unusual case is reported where prolonged remission was obtained. Immunohistochemical staining of the bone marrow trephine biopsy specimen proved invaluable in documenting early relapse. It is suggested that immunohistochemistry should be adopted more widely...

journal_title：Journal of clinical pathology

authors： Kettle P,Morris TC

更新日期：1994-08-01 00:00:00

abstract：AIM:The immunoproteasome is a specific proteasome isoform whose proteolytic activity enhances the generation of antigenic peptides to be presented by major histocompatibility complex class I molecules to CD8+ T cells. Physiologically, it is expressed abundantly in immune cells and is induced in somatic cells by cytokin...

journal_title：Journal of clinical pathology

authors： Kiuchi T,Tomaru U,Ishizu A,Imagawa M,Iwasaki S,Suzuki A,Otsuka N,Ohhara Y,Kinoshita I,Matsuno Y,Dosaka-Akita H,Kasahara M

更新日期：2020-09-17 00:00:00

abstract：:Two types of lymphocyte tubular structures were studied by electron microscopy in 80 patients with classic or definite rheumatoid arthritis (RA). Fifteen patients with unequivocal systemic lupus erythematosus (SLE) and 10 healthy persons were studied as controls. Lymphocyte tubulo-reticular structures were found in 13...

journal_title：Journal of clinical pathology

authors： Dryll A,Cazalis P,Ryckewaert A

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The TNM classification for renal cell cancer (RCC) should accurately predict and assign prognostic information for patients. In this study the recent 2010 revision to the TNM classification was compared with the previous 2002 classification with regard to survival outcomes. METHODS:All patients having radic...

journal_title：Journal of clinical pathology

authors： Veeratterapillay R,Simren R,El-Sherif A,Johnson MI,Soomro N,Heer R

更新日期：2012-04-01 00:00:00

abstract：:A case of B-CLL which was complicated by chronic renal failure due to leukaemic infiltration of the kidney is reported. Treatment with chlorambucil, prednisolone, and renal bed irradiation resulted in a substantial improvement in renal function which persisted until the the patient's death from marrow failure some eig...

journal_title：Journal of clinical pathology

authors： Phillips JK,Bass PS,Majumdar G,Davies DR,Jones NF,Pearson TC

更新日期：1993-12-01 00:00:00

abstract：AIMS:To establish a three dimensional reconstruction of an invasive breast carcinoma using basic laboratory equipment to evaluate and characterise the spatial arrangement of the parenchymal cells of the breast. METHODS:One hundred and twenty eight sequential 4 microm sections (20 microm apart) of the tumour were stain...

journal_title：Journal of clinical pathology

authors： Kurien T,Boyce RW,Paish EC,Ronan J,Maddison J,Rakha EA,Green AR,Ellis IO

更新日期：2005-09-01 00:00:00

abstract：:Leucocyte ascorbate (LA) and serum ascorbate (SA) were measured in patients who had sustained an acute cerebrovascular accident. There was a significant fall in LA and Sa within 24 hours of the incident and this persisted for several weeks. The "stress" of the event resulted in a rise in serum cortisol concentration a...

journal_title：Journal of clinical pathology

authors： Hume R,Vallance BD,Muir MM

更新日期：1982-02-01 00:00:00

abstract：:Performance of CHROMagar Acinetobacter was assessed for the selective isolation and identification of Acinetobacter baumannii. The medium was effective in suppressing the growth of other Gram-positive and Gram-negative species while the addition of KPC supplement ensured growth of only carbapenem resistant A baumannii...

journal_title：Journal of clinical pathology

authors： Wareham DW,Gordon NC

更新日期：2011-02-01 00:00:00

abstract：:Advanced non-small cell lung cancer samples are tested for epidermal growth factor receptor (EGFR) gene mutations. Their detection by direct sequencing is time-consuming. Conversely, the length analysis of fluorescently labelled PCR products is easier. To avoid labelled primers and the automated capillary electrophore...

journal_title：Journal of clinical pathology

authors： Malapelle U,Russo S,Pepe F,Sgariglia R,De Luca C,Bellevicine C,Pallante P,Troncone G

更新日期：2013-11-01 00:00:00

abstract：AIMS:Traditionally, advanced stage ovarian carcinoma is treated by debulking surgery followed by chemotherapy. However, in some circumstances preoperative chemotherapy may be given before optimal surgical debulking. This study aims to describe the morphological features found in ovarian carcinoma after chemotherapy bec...

journal_title：Journal of clinical pathology

authors： McCluggage WG,Lyness RW,Atkinson RJ,Dobbs SP,Harley I,McClelland HR,Price JH

更新日期：2002-01-01 00:00:00

abstract：AIM:To determine whether the pattern of involvement of the gastric mucosa in lymphocytic gastritis is predictive of the presence or absence of duodenal pathology. METHODS:50 cases (M:F, 26:24; median age 57 years) diagnosed as lymphocytic gastritis between 1986 and 1998 with concurrent duodenal (D2) biopsies were iden...

journal_title：Journal of clinical pathology

authors： Hayat M,Arora DS,Wyatt JI,O'Mahony S,Dixon MF

更新日期：1999-11-01 00:00:00

abstract：:An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at al...

journal_title：Journal of clinical pathology

authors： Tapper-Jones L,Aldred M,Walker DM

更新日期：1980-03-01 00:00:00

abstract：:The indirect immunofluorescence technique was used to study the expression of the blood group A and H antigens in fresh-frozen and formalin-fixed paraffin-embedded sections of the bladder mucosa of 21 patients with non-neoplastic diseases of the bladder. Reliable assessment of these antigens could only be made using c...

journal_title：Journal of clinical pathology

authors： Thorpe SJ,Abel P,Slavin G,Feizi T

更新日期：1983-08-01 00:00:00

abstract：:The effect of acute hypoglycaemia on platelet function was examined in patients undergoing an insulin stress test. Enhanced platelet aggregation was observed in all cases but platelet count, platelet adenine nucleotides, and the plasma level of von Willebrand factor were unchanged overall. The onset of the hypoglycaem...

journal_title：Journal of clinical pathology

authors： Hutton RA,Mikhailidis D,Dormandy KM,Ginsburg J

更新日期：1979-05-01 00:00:00

abstract：:This study has shown that different supplies/batches of orcein perform differently and may fail. The "natural" forms generally performed better although the most informative results were obtained with a "synthetic" product. Orcein dye solutions can be used soon after preparation and for up to 7 days without the need f...

journal_title：Journal of clinical pathology

authors： Kirkpatrick P

更新日期：1982-04-01 00:00:00

abstract：:The usefulness of placental alkaline phosphatase (PLAP) as a diagnostic marker of malignancy was assessed in pleural fluid from 60 patients with effusions. Pleural fluid PLAP activities were measured by an enzyme linked immunoassay (ELISA) using the two monoclonal antibodies H17E2 and H317. Similar values were found i...

journal_title：Journal of clinical pathology

authors： Fergusson RJ,Fisken J,McIntyre MA,Roulston JE,Leonard RC

更新日期：1992-12-01 00:00:00

abstract：AIM:To investigate the tissue specificity of a novel monoclonal antibody raised to a tissue fraction of normal human liver and which identified certain cells of gastric and duodenal mucosa. METHODS:A total of 155 samples of various tissues obtained from 100 surgical specimens were fixed in cold ethanol-paraformaldehyd...

journal_title：Journal of clinical pathology

authors： Hughes NR,Bhathal PS,Francis DM

更新日期：1994-01-01 00:00:00

abstract：:Polymorphous low-grade adenocarcinoma (PLGA) is a rare tumour that mostly affects oral minor salivary glands. Our review of the literature found that there are only two reported cases of PLGA originating in the nasopharynx. Another nasopharyngeal PLGA in a 14-year-old boy is reported, focusing on the histopathological...

journal_title：Journal of clinical pathology

authors： Wei YC,Huang CC,Chien CY,Hwang JC,Chen WJ

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Acute B lymphoblastic leukaemia (B-ALL) is the most common type of childhood malignancy worldwide but little is known of its origin. Recently, many studies showed both a high incidence of Epstein-Barr virus (EBV) infection and high levels of CD4+CD25+Foxp3+(Treg cells) in children with B-ALL. In our study, we...

journal_title：Journal of clinical pathology

authors： Ateyah ME,Hashem ME,Abdelsalam M

更新日期：2017-02-01 00:00:00

abstract：:Two cases of Wegener's granulomatosis are described in which the early and predominating lesions were found in the breast. The histological features of breast necrosis with granulomatous inflammation and widespread vasculitis in the breast in the absence of any demonstrable pathogens enabled a presumptive diagnosis to...

journal_title：Journal of clinical pathology

authors： Pambakian H,Tighe JR

更新日期：1971-05-01 00:00:00

abstract：BACKGROUND:In experimental glomerulonephritis, inhibition of cyclooxygenase 2 (COX-2) enhances the renocortical expression of pathogenic alpha(v) integrins. AIMS:To study whether this effect is mediated by prostaglandin E(2) (PGE(2)) acting through its EP(3) receptor in cultured rat mesangial cells (MCs). METHODS:MCs...

journal_title：Journal of clinical pathology

authors： Waldner C,Schrör K,Heering P

更新日期：2004-05-01 00:00:00