Bone marrow fibrosis in acute lymphoblastic leukaemia of childhood.

Abstract:

:A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provided useful information in different diagnosis and when aspiration was difficult, it provided little information of use for management.

journal_name

J Clin Pathol

authors

Hann IM,Evans DI,Marsden HB,Jones PM,Palmer MK

doi

10.1136/jcp.31.4.313

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

313-5

issue

4

eissn

0021-9746

issn

1472-4146

journal_volume

31

pub_type

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