Lymphocyte tubular structures in rheumatoid arthritis.

abstract：:When the posture was changed from horizontal to vertical, or the reverse, the alteration in plasma volume and in the levels of haematocrit, haemoglobin, and plasma protein was much greater in patients with oedema or low plasma protein or albumin concentrations ("the pathological group") than in patients without these ...

journal_title：Journal of clinical pathology

authors： FAWCETT JK,WYNN V

更新日期：1960-07-01 00:00:00

abstract：:The fetal antigen i has been demonstrated by indirect immunofluorescence on cord erythrocytes and placental trophoblast. A patient with disseminated choriocarcinoma developed high-tire anti-i cold agglutinins, and minor elevation of anti-i titres was seen in four out of six further patients with treated choriocarcinom...

journal_title：Journal of clinical pathology

authors： Boughton BJ

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Over 90% of Ewing's sarcoma/primitive neuroectodermal tumour (ES/PNET) cases have the t(11;22) chromosomal rearrangement, which is also found in other small round cell tumours, including desmoplastic small round cell tumour (DSRCT) and clear cell sarcoma (CCS). Although this rearrangement can be analysed by ...

journal_title：Journal of clinical pathology

authors： Yamaguchi U,Hasegawa T,Morimoto Y,Tateishi U,Endo M,Nakatani F,Kawai A,Chuman H,Beppu Y,Endo M,Kurotaki H,Furuta K

更新日期：2005-10-01 00:00:00

abstract：AIMS:To evaluate and compare the long term prognostic value of the WHO classification and the computerised multivariate morphometrical D score in endometrial hyperplasia. To test the reproducibility of the D score in two different centres. METHODS:Histopathological WHO classification and computerised morphometrical an...

journal_title：Journal of clinical pathology

authors： Orbo A,Baak JP,Kleivan I,Lysne S,Prytz PS,Broeckaert MA,Slappendel A,Tichelaar HJ

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Friend leukaemia integration-1 (FLI-1) antibody is a useful marker for Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET) and vascular tumours. However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT). AIM:To de...

journal_title：Journal of clinical pathology

authors： Mhawech-Fauceglia P,Herrmann FR,Bshara W,Odunsi K,Terracciano L,Sauter G,Cheney RT,Groth J,Penetrante R,Mhawech-Fauceglia P

更新日期：2007-06-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the mismatch repair gene expression and their correlation with NF-kB in patients with oral squamous cell carcinoma (SCC). METHODS:Total RNA was isolated from 28 biopsy samples. A control group was composed of 20 volunteers. Differential expression of hMSH2, hMSH6 and NF-kB ge...

journal_title：Journal of clinical pathology

authors： Fonseca A,Perez M,Veiga G,Prosdócimi F,Nunes F,Bianco B,Fonseca F,Alves B

更新日期：2020-05-01 00:00:00

abstract：:As part of a quality assurance programme at the Aga Khan University Medical Centre, Karachi, Pakistan, all hysterectomy specimens were reviewed from January 1986 to December 1989. Adenomyosis was found in 237 of the 419 (56.5%) specimens studied. Of these 237 patients, 232 (97.9%) were parous and 196 (82.8%) were in t...

journal_title：Journal of clinical pathology

authors： Shaikh H,Khan KS

更新日期：1990-10-01 00:00:00

abstract：AIM:The earlier detection of breast cancer through mammographic screening has resulted in a shift in stage distribution with patients who are node-positive tending to present with a lower number of positive lymph nodes (LN). This study aims to assess the prognostic value of absolute number of positive nodes in the pN1 ...

journal_title：Journal of clinical pathology

authors： Rakha EA,Morgan D,Macmillan D

更新日期：2012-07-01 00:00:00

abstract：:Serum lysozyme levels were determined by a turbidometric method using egg white lysozyme as standard in 100 patients with Crohn's disease, 86 with ulcerative colitis, 31 with coeliac disease, and in 38 normal control subjects. Though the levels in Crohn's disease were significantly higher than those in ulcerative coli...

journal_title：Journal of clinical pathology

authors： Mallas E,Terry JM,Asquith P,Cooke WT

更新日期：1976-07-01 00:00:00

abstract：:Visceral candidiasis in 56 patients, 39 of whom were thought to be immune deficient, was investigated using three serological detection methods--whole cell agglutination, haemagglutination, and counterimmunoelectrophoresis for antibodies; two determinations of circulating antigens--haemagglutination inhibition and lat...

journal_title：Journal of clinical pathology

authors： Platenkamp GJ,Van Duin AM,Porsius JC,Schouten HJ,Zondervan PE,Michel MF

更新日期：1987-10-01 00:00:00

abstract：AIMS:To determine whether the recommended methods for the handling of breast excision biopsy specimens from screening patients cause more laboratory work than those used for non-screening patients. METHODS:All breast excision biopsy specimens from 1990 were identified. Ninety one came from patients identified during t...

journal_title：Journal of clinical pathology

authors： Green B,McDicken IW,Turnbull LS

更新日期：1992-06-01 00:00:00

abstract：:The use of the dye calcon (1-(2 hydroxy-1-naphthylazo)-2-naphthol-4 sulphonic acid) for the estimation of calcium using E.D.T.A. and a commercial photoelectric titrimeter is described. The interfering effects of magnesium and phosphate have been overcome. The method has been extended to estimations on biological mater...

journal_title：Journal of clinical pathology

authors： BOWDEN CH,PATSTON VJ

更新日期：1963-01-01 00:00:00

abstract：:Statistical tables including 50 and 95 percentile ranges are presented of the combined kidney weights compared with body weight, crown-rump length, and gestation age of foetuses and newborn children, and also a table of kidney weights related to post-natal age. The importance of relating kidney weight to more than one...

journal_title：Journal of clinical pathology

authors： EMERY JL,MITHAL A

更新日期：1960-11-01 00:00:00

abstract：:Evaluation of histological diagnosis requires an index of agreement (to measure repeatability and validity) together with a method of assessing bias. Cohen's kappa statistic appears to be the most suitable tool for measuring levels of agreement, which if unsatisfactory may be caused by bias. Further study of bias is p...

journal_title：Journal of clinical pathology

authors： Silcocks PB

更新日期：1983-11-01 00:00:00

abstract：CLINICAL QUESTION:A 45-year-old woman presented with painless vaginal bleeding for 2 months. A biopsy was taken from the uterine cervix, and poorly differentiated adenocarcinoma was suspected. After three cycles of neoadjuvant chemotherapy treatment, the patient underwent radical hysterectomy with bilateral salpingo-oo...

journal_title：Journal of clinical pathology

authors： Ling C,Shen Y

更新日期：2018-11-01 00:00:00

abstract：:Liver function was assessed in 38 Edinburgh haemophiliacs. Results before the introduction of NHS intermediate factor VIII concentrate from 1974 onwards were compared with values in 1979. Measurements of serum bile salts in 16 patients as well as conventional liver function tests gave useful evidence of deranged liver...

journal_title：Journal of clinical pathology

authors： Stirling ML,Beckett GJ,Percy-Robb IW

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The prognosis of adenoid cystic carcinoma (ACC), a malignant salivary gland tumour, depends on clinicopathological parameters. To decipher the biological behaviour of ACC, and to identify patients at risk of developing metastases, additional markers are needed. METHODS:Expression of the cell cycle proteins ...

journal_title：Journal of clinical pathology

authors： Vékony H,Raaphorst FM,Otte AP,van Lohuizen M,Leemans CR,van der Waal I,Bloemena E

更新日期：2008-06-01 00:00:00

abstract：:The T(4)-free thyroxine index was used as the thyroid function test of first choice in a district general hospital for one year. Ninety-two patients were assessed both initially and at follow up by a single physician. The index agreed with clinical assessment in 69 out of 74 patients in whom diagnosis was unequivocal....

journal_title：Journal of clinical pathology

authors： Howorth PJ,Ward RL

更新日期：1972-03-01 00:00:00

abstract：AIMS:The perforin mediated pathway is the major pathway of cytotoxicity induced by activated T cells and natural killer cells, and may be involved in the development of pulmonary fibrosis. METHODS:Perforin and granzyme B expression were examined in idiopathic pulmonary fibrosis by means of immunohistochemistry, and pe...

journal_title：Journal of clinical pathology

authors： Miyazaki H,Kuwano K,Yoshida K,Maeyama T,Yoshimi M,Fujita M,Hagimoto N,Yoshida R,Nakanishi Y

更新日期：2004-12-01 00:00:00

abstract：:As part of a study to establish the prevalence of renal calculus disease, alkaline phosphatase activity was measured by the method recommended by the Scandinavian Society for Clinical Chemistry and Clinical Physiology in the plasma of 3823 adults from the Scottish new town of Cumbernauld. The enzyme activity differs i...

journal_title：Journal of clinical pathology

authors： Gardner MD,Scott R

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:The "classical" antineutrophil cytoplasmic antibody (C-ANCA) pattern seen on indirect immunofluorescence (IIF) is characterised by granular cytoplasmic staining showing central or interlobular accentuation, and is strongly associated with antiproteinase-3 antibodies (PR3-ANCA) and Wegener's granulomatosis. H...

journal_title：Journal of clinical pathology

authors： Wong RC,Silvestrini RA,Savige JA,Fulcher DA,Benson EM

更新日期：1999-02-01 00:00:00

abstract：:Leucocyte ascorbate (LA) and serum ascorbate (SA) were measured in patients who had sustained an acute cerebrovascular accident. There was a significant fall in LA and Sa within 24 hours of the incident and this persisted for several weeks. The "stress" of the event resulted in a rise in serum cortisol concentration a...

journal_title：Journal of clinical pathology

authors： Hume R,Vallance BD,Muir MM

更新日期：1982-02-01 00:00:00

abstract：:Malignant extrarenal rhabdoid tumour (MERT) of the gastrointestinal tract is rarely reported in the literature. This report describes the clinical and pathological features of a malignant rhabdoid tumour of the oesophagus in a Chinese man. Ivor-Lewis oesophagectomy had been performed. The tumour behaved aggressively a...

journal_title：Journal of clinical pathology

authors： Ng WC,Leong HT,Ma KF,Yip WL,Suen WM

更新日期：2003-09-01 00:00:00

abstract：AIMS:To evaluate the IRIS flow microscope for the examination of urine specimens and to compare its performance with that of manual methods; in addition, to assess its usefulness as a screening system for the detection of significant bacteriuria in a routine clinical laboratory. METHODS:The IRIS system was compared wi...

journal_title：Journal of clinical pathology

authors： Hughes C,Roebuck MJ

更新日期：2003-11-01 00:00:00

abstract：:A radioimmunoassay for the measurement of gonadotrophin releasing hormone (GnRH) in plasma and urine using readily available reagents was developed. The GnRH assay showed good precision, recovery, and parallelism over a wide range of GnRH concentrations with a sensitivity of 15 pg/ml. The assay was compared with a com...

journal_title：Journal of clinical pathology

authors： Mosby VA,Knapp ML,Fink RS,Osgood VM,Mayne PD

更新日期：1989-05-01 00:00:00

abstract：INTRODUCTION:Modification of the spiral arteries with loss of the muscular vascular wall, invaded by the trophoblasts, represents the goal of the physiological vascular adaptation during human implantation. When physiological vascular changes do not occur, an unfavourable evolution of gestation may develop as suggested...

journal_title：Journal of clinical pathology

authors： Avagliano L,Bulfamante GP,Morabito A,Marconi AM

更新日期：2011-12-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00

abstract：AIMS:To investigate proliferative activity in leukaemic and lymphomatous bone marrow infiltrates and to assess the feasibility of transport of specimens among institutions. METHODS:Proliferative activity in bone marrow trephine cryosections from 99 patients with non-Hodgkin's lymphoma (NHL), 23 patients with acute mye...

journal_title：Journal of clinical pathology

authors： White DM,Smith AG,Smith JL

更新日期：1994-03-01 00:00:00

abstract：:Gastrointestinal cell proliferation plays an important role in the maintenance of the integrity of the gastrointestinal system. The study of gastrointestinal proliferation kinetics allows a better understanding of the complexity of the system, and also has important implications for the study of gastrointestinal carci...

journal_title：Journal of clinical pathology

authors： Wong WM,Wright NA

更新日期：1999-05-01 00:00:00

abstract：:A middle aged man developed very high fever, status epilepticus, and terminal acute renal failure with myoglobinuria after surgery. A post mortem examination showed widespread muscle necrosis with hypercontraction bands. Muscle enzyme studies and electron microscopic examination disclosed central core disease, a condi...

journal_title：Journal of clinical pathology

authors： Prescott RJ,Roberts SP,Williams G

更新日期：1992-04-01 00:00:00