Ascorbate status and fibrinogen concentrations after cerebrovascular accident.

Abstract:

:Leucocyte ascorbate (LA) and serum ascorbate (SA) were measured in patients who had sustained an acute cerebrovascular accident. There was a significant fall in LA and Sa within 24 hours of the incident and this persisted for several weeks. The "stress" of the event resulted in a rise in serum cortisol concentration and depletion of both pituitary and adrenal glands of ascorbate when examined at post mortem. Serum fibrinogen concentrations also rose above normal. The role of ascorbate in pituitary and adrenal function and the relation of ascorbate to acute and chronic vascular disorders has still to be established.

journal_name

J Clin Pathol

authors

Hume R,Vallance BD,Muir MM

doi

10.1136/jcp.35.2.195

subject

Has Abstract

pub_date

1982-02-01 00:00:00

pages

195-9

issue

2

eissn

0021-9746

issn

1472-4146

journal_volume

35

pub_type

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