Unusually high incidence of tuberculosis among boys with haemophilia during an outbreak of the disease in hospital.

abstract：BACKGROUND/AIMS:In the natural history of gastric cancer, non-invasive neoplasia (NiN) precedes invasive carcinoma. A histological classification of gastric NiN has recently been proposed by a World Health Organisation international panel of experts. Genetic instability is known to be among the molecular pathways invol...

journal_title：Journal of clinical pathology

authors： Rugge M,Bersani G,Bertorelle R,Pennelli G,Russo VM,Farinati F,Bartolini D,Cassaro M,Alvisi V

更新日期：2005-08-01 00:00:00

abstract：AIMS:To investigate the correlation between centrally assessed human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) results and response to treatment of patients with metastatic breast cancer enrolled in a first-line, phase II, open-label, 3-weekly tra...

journal_title：Journal of clinical pathology

authors： Hofmann M,Stoss O,Gaiser T,Kneitz H,Heinmöller P,Gutjahr T,Kaufmann M,Henkel T,Rüschoff J

更新日期：2008-01-01 00:00:00

abstract：AIMS:To use the polymerase chain reaction to detect monoclonality at the immunoglobulin heavy chain gene locus in cells derived from lymph node aspirates. METHODS:A nested two-stage polymerase chain reaction (PCR) for the VDJ region of the immunoglobulin heavy chain gene was used to detect monoclonality. The total num...

journal_title：Journal of clinical pathology

authors： Wan JH,Sykes PJ,Orell SR,Morley AA

更新日期：1992-05-01 00:00:00

abstract：:Haemoglobin (Hb) Bonn is a newly described benign Hb variant that causes falsely depressed oxygen saturation as measured by pulse oximetry. It was found to be associated with mild haemolysis. Since its first report in a German family, no further cases have been documented in the literature. We report the first Chinese...

journal_title：Journal of clinical pathology

authors： So CC,Chan AY,Chow EY,Lin SY,Yip SF,Szeto SC,Chan LC

更新日期：2010-10-01 00:00:00

abstract：:This report describes a case of refractory enteropathy with circulating intestinal goblet cell autoantibodies (IGA). A 19 year old man with hyperthyroidism had suffered from protracted diarrhoea for nearly 10 years. Histological examination showed evidence of collagenous enterocolitis. The diarrhoea did not improve de...

journal_title：Journal of clinical pathology

authors： Hori K,Fukuda Y,Tomita T,Kosaka T,Tamura K,Nishigami T,Kubota A,Shimoyama T

更新日期：2003-08-01 00:00:00

abstract：:The effect of the new beta-lactam antibiotic FL 1060 on urinary tract pathogens, of which 71 were sensitive to and 100 resistant to ampicillin, is presented here. When tested by conventional methods FL 1060 was found to be highly active against ampicillin-sensitive strains of E. coli but phenotypically resistant varia...

journal_title：Journal of clinical pathology

authors： Greenwood D,Brooks HL,Gargan R,O'Grady F

更新日期：1974-03-01 00:00:00

abstract：:A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discusse...

journal_title：Journal of clinical pathology

authors： Burns GF,Cawley JC,Flemans RJ,Higgy KE,Worman CP,Barker CR,Roberts BE,Hayhoe FG

更新日期：1977-10-01 00:00:00

abstract：:The thyroids of primary thyrotoxicosis patients prepared for partial thyroidectomy with propranolol contained much more lymphoid infiltrate than those prepared with carbimazole. No relation was found between the extent of lymphoid infiltrate in the thyroid and the development of postoperative hypothyroidism either bet...

journal_title：Journal of clinical pathology

authors： Young RJ,Sherwood MB,Simpson JG,Nicol AG,Michie W,Beck JS

更新日期：1976-05-01 00:00:00

abstract：:Using a radioimmunoassay technique serum alpha-fetoprotein could be detected in healthy adults in concentrations of less than 20 microgram/l. Of patients with acute, viral hepatitis 43% exhibited a transient rise of serum alpha-fetoprotein, the peak occurring eight to nine days after the maximum recorded serum asparta...

journal_title：Journal of clinical pathology

authors： Eleftheriou N,Heathcote J,Thomas HC,Sherlock S

更新日期：1977-08-01 00:00:00

abstract：AIMS:To investigate the physical status of human papillomavirus 16 (HPV-16) in low grade squamous intraepithelial lesions (LSILs) as a means of determining the percentage of viral integration. METHODS:Ninety two LSIL/HPV positive Thin Prep(TM) samples were initially tested for the E6 gene by the polymerase chain react...

journal_title：Journal of clinical pathology

authors： Gallo G,Bibbo M,Bagella L,Zamparelli A,Sanseverino F,Giovagnoli MR,Vecchione A,Giordano A

更新日期：2003-07-01 00:00:00

abstract：:The incidence of jaundice and of abnormal liver function tests has been assessed in 91 multitransfused patients with severe haemophilia A and B. Tests of hepatocyte function were within the normal range in the majority of patients. On the contrary, tests of biliary cell function, liver cell damage, and bromsulphthalei...

journal_title：Journal of clinical pathology

authors： Mannucci PM,Capitanio A,Del Ninno E,Colombo M,Pareti F,Ruggeri ZM

更新日期：1975-08-01 00:00:00

abstract：AIMS:To show that medullary carcinomas of the thyroid are morphologically indistinguishable from gut carcinoids: the value of histochemistry in their identification and differential diagnosis from metastatic carcinoid tumours to the thyroid and some follicular cell neoplasms. METHODS:15 thyroid medullary carcinomas wi...

journal_title：Journal of clinical pathology

authors： Harach HR,Bergholm U

更新日期：1993-02-01 00:00:00

abstract：AIMS:To investigate the occurrence of abnormal patterns of HLA-ABC and HLA-DR expression in enteropathy associated T cell lymphoma and to relate such abnormalities to the Epstein Barr virus (EBV) status of the tumours. METHODS:Eleven enteropathy associated T cell lymphomas were immunostained with HC10 (HLA-ABC heavy c...

journal_title：Journal of clinical pathology

authors： Ashton-Key M,Singh N,Pan LX,Smith ME

更新日期：1996-07-01 00:00:00

abstract：:Results of blood culture examination using the radiometric (Bactec-460) system for one year showed no overall improvement compared with those of the previous three years when a manual system with early blind subculture was used. The isolates from the manual system were available more often on solid media, 24 hours ear...

journal_title：Journal of clinical pathology

authors： Ganguli LA,Keaney MG,Hyde WA,Fraser SB

更新日期：1985-10-01 00:00:00

abstract：AIMS:To compare the sensitivity and specificity of new rabbit monoclonal antibody SP3 with those of mouse monoclonal and rabbit polyclonal antibodies using HER2 amplification defined by chromogenic in situ hybridisation (CISH) as the gold standard. METHODS:Serial sections from tissue microarrays (TMAs) containing 84 b...

journal_title：Journal of clinical pathology

authors： Nunes CB,Rocha RM,Reis-Filho JS,Lambros MB,Rocha GF,Sanches FS,Oliveira FN,Gobbi H

更新日期：2008-08-01 00:00:00

abstract：:Three cases of islet cell necrosis in neonates are reported. The association of this rare condition with antepartum haemorrhage, anoxia, shock and intravascular coagulation are discussed. The clinical and morphological appearances were compared with previous descriptions of this condition and an association with neona...

journal_title：Journal of clinical pathology

authors： Roberts PF

更新日期：1987-10-01 00:00:00

abstract：:This report describes a patient with a gastric biopsy specimen showing histomorphological and immunohistochemical appearances indistinguishable from those usually present in lymphocytic gastritis, a rare condition of unknown aetiology with a distinctive phenotype. The patient had a history of a biopsy confirmed T cell...

journal_title：Journal of clinical pathology

authors： Nga ME,Tan SH,Teh M,Koay ES,Chong SM,Putti TC,Salto-Tellez M

更新日期：2004-11-01 00:00:00

abstract：:Antibodies against alpha smooth muscle actin (ASMA) and S100 protein were applied to paraffin wax embedded sections from 40 salivary gland tumours and seven normal salivary glands. The results indicate that ASMA is useful in the diagnosis of epithelial-myoepithelial carcinoma, but is otherwise only of limited use in d...

journal_title：Journal of clinical pathology

authors： Jones H,Moshtael F,Simpson RH

更新日期：1992-10-01 00:00:00

abstract：:The excretion of 2,3-dinor-6-keto prostaglandin F1 alpha, a major urinary metabolite of prostacyclin, and the formation of thromboxane B2, a stable metabolite of thromboxane A2, by platelets stimulated by adenosine diphosphate, were studied in alcoholics, who had been admitted for detoxification. Once prolonged heavy ...

journal_title：Journal of clinical pathology

authors： Neiman J,Hillbom M,Benthin G,Anggård EE

更新日期：1987-05-01 00:00:00

abstract：:An elution technique is described which gives eluates at least as potent as previously described methods. Elution can be completed in only 15 minutes. The method, a modification of that of Vos and Kelsall, is simple to carry out and requires the minimum of equipment. Studies have shown that the coating antibody is alm...

journal_title：Journal of clinical pathology

authors： RUBIN H

更新日期：1963-01-01 00:00:00

abstract：AIMS:The chemokine receptor CXCR7 is found on glioma cells and glioma-associated vessels and dependent upon its localisation on tumour or endothelial cells the CXCR7 receptor can mediate glioma cell invasion and tumour angiogenesis. Its expression predicts survival in several types of cancers. METHODS:We immunohistoch...

journal_title：Journal of clinical pathology

authors： Birner P,Tchorbanov A,Natchev S,Tuettenberg J,Guentchev M

更新日期：2015-10-01 00:00:00

abstract：:This paper illustrates a simple method of necropsy dissection of the abdominal organs after abdominal surgery. The organs are removed in one block as per the method described by Letulle. A retroperitoneal approach is then used. Structures are dissected away in a series of layers using the vasculature for guidance. Thi...

journal_title：Journal of clinical pathology

authors： Culora GA,Roche WR

更新日期：1996-09-01 00:00:00

abstract：:Pseudomonas cepacia (Ps. multivorans) can become adapted to a 1 in 30 dilution of Savlon hospital concentrate in distilled water, and can multiply in it. The organism so adapted did not survive in Savlon of the same strength made with hard tap water (pH 7.2). This effect was due to the difference of pH between the two...

journal_title：Journal of clinical pathology

authors： Bassett DC

更新日期：1971-11-01 00:00:00

abstract：:Thirty two fire victims with smoke inhalation, with or without burns, and 26 control subjects had bronchoalveolar lavage performed. Cell yields and differential cell counts were assessed. All patients and controls were cigarette smokers. Patients with smoke inhalation (SI) injury generally showed higher total bronchoa...

journal_title：Journal of clinical pathology

authors： Riyami BM,Tree R,Kinsella J,Clark CJ,Reid WH,Campbell D,Gemmell CG

更新日期：1990-01-01 00:00:00

abstract：:Routine endometrial cytology was used instead of curettage as the first step in a morphological investigation of the endometrium in patients with postmenopausal bleeding. Premenopausal women with symptoms or signs indicative of premalignant or malignant disease were also studied using this method. Patients with alarmi...

journal_title：Journal of clinical pathology

authors： Skaarland E

更新日期：1986-01-01 00:00:00

abstract：:This review of the histomorphometry of bone outlines methods of biopsy and processing of specimens in the laboratory, the basic principles of morphometry, and the measurements made in order to obtain estimates of the proportional volumes and surfaces occupied by different components of bone. Variability such as that b...

journal_title：Journal of clinical pathology

authors： Revell PA

更新日期：1983-12-01 00:00:00

abstract：AIMS:To evaluate the efficacy of biochemical parameters in different fluids in the diagnosis of myocardial infarction of different causes, analysed after death. METHODS:The myoglobin concentration and total creatine kinase (CK) and creatine kinase MB isoenzyme (CK-MB) activities were measured in serum, pericardial flu...

journal_title：Journal of clinical pathology

authors： Perez-Cárceles MD,Osuna E,Vieira DN,Martínez A,Luna A

更新日期：1995-02-01 00:00:00

abstract：AIMS:To evaluate the effect of 10 day triple treatment on H pylori eradication and associated gastritis. METHODS:Fifty patients with H pylori positive non-ulcer dyspepsia were treated for 10 days with amoxicillin, tinidazole, and bismuth salts. Histological examination of the antral mucosa was performed before (T0), s...

journal_title：Journal of clinical pathology

authors： Di Napoli A,Petrino R,Boero M,Bellis D,Chiandussi L

更新日期：1992-09-01 00:00:00

abstract：AIM:To investigate morphological changes in the tumour vessel adventitia, particularly the distribution of vascular adventitial fibroblastic cells (VAFCs)--namely, CD34 positive fibroblastic cells just outside the vascular media--in diffuse-type gastric carcinomas. METHOD:In total, 18 surgically resected advanced typi...

journal_title：Journal of clinical pathology

authors： Nakayama H,Enzan H,Miyazaki E,Kuroda N,Toi M,Hiroi M,Yasui W

更新日期：2004-09-01 00:00:00

abstract：:A method for identifying Helicobacter pylori using a non-isotopic in situ hybridisation technique is described. A probe generated by polymerase chain reaction (PCR) with primers directed against parts of the Helicobacter pylori 16SrRNA sequence was used. Paraffin wax embedded gastric biopsy specimens from patients wit...

journal_title：Journal of clinical pathology

authors： Bashir MS,Lewis FA,Quirke P,Lee A,Dixon MF

更新日期：1994-09-01 00:00:00