More rapid identification of bacteraemia by manual rather than radiometric method.

abstract：UNLABELLED:Encapsulated papillary carcinoma (EPC) of the breast is a distinct histological subtype characterised by malignant epithelial proliferation supported by fibrovascular stalks. Although EPC typically lacks myoepithelial cells, it shows indolent clinical course. The classification of EPC as an in situ, or invas...

journal_title：Journal of clinical pathology

authors： Rakha EA,Tun M,Junainah E,Ellis IO,Green A

更新日期：2012-08-01 00:00:00

abstract：AIM:To establish the diagnostic value of in situ hybridisation and the nested polymerase chain reaction (PCR) in detecting clinically relevant cytomegalovirus (CMV) infection in upper gastrointestinal biopsies from heart transplant patients. METHODS:Test sensitivity and specificity for detection of CMV early gene RNA ...

journal_title：Journal of clinical pathology

authors： Muir SW,Murray J,Farquharson MA,Wheatley DJ,McPhaden AR

更新日期：1998-11-01 00:00:00

abstract：AIMS:Common variable immunodeficiency (CVID) is the most common serious primary immunodeficiency. This paper describes the immunological consequences of human immunodeficiency virus (HIV) infection in a patient with familial CVID subsequently treated with highly active antiretroviral therapy (HAART). METHODS:Serial me...

journal_title：Journal of clinical pathology

authors： Jolles S,Tyrer M,Johnson M,Webster D

更新日期：2001-09-01 00:00:00

abstract：:The aggregating effects of adenosine diphosphate, thrombin, 5-hydroxytryptamine, tryptamine, adrenaline and noradrenaline, and tri-ethyl tin have been carefully compared. The first three compounds in some circumstances produce remarkably similar effects although there are important differences. The kinetics of aggrega...

journal_title：Journal of clinical pathology

authors： O'BRIEN JR

更新日期：1964-05-01 00:00:00

abstract：:In a study of a group of 325 blood donors between the ages of 18 and 65 years, the total leucocyte and polymorph counts of the females aged 50 to 65 years were found to be significantly lower than those of the corresponding group of male donors. In the whole series of female donors, there were significantly lower tota...

journal_title：Journal of clinical pathology

authors： Allan RN,Alexander MK

更新日期：1968-11-01 00:00:00

abstract：:The only method currently available to perform Neisseria gonorrhoeae antimicrobial susceptibility testing (Ng-AST) requires a viable organism obtained by culture. Reports of in vitro resistance to extended-spectrum cephalosporins, the treatment of choice for gonorrhoea, coupled with increasing gonorrhoea diagnoses is ...

journal_title：Journal of clinical pathology

authors： Jain A,Cole MJ,Planche T,Ison CA

更新日期：2014-11-01 00:00:00

abstract：:Fluorigenic substrates prepared from 4-methylumbelliferone provide a simple, convenient method for detecting and assaying group-specific hydrolase activity in small quantities of whole mycobacteria. Physico-chemical properties of the enzymes such as pH dependence and heat stability may also be studied. A technique is ...

journal_title：Journal of clinical pathology

authors： Grange JM

更新日期：1978-04-01 00:00:00

abstract：:The case records and pathology of all children with kidney tumours treated in the West Midlands Health Authority Region (WMHAR) from 1957 to 1986 were reviewed. The histology was reviewed by a panel of three paediatric pathologists. Thirteen (6%) out of 211 cases were considered to have congenital mesoblastic nephroma...

journal_title：Journal of clinical pathology

authors： Barrantes JC,Toyn C,Muir KR,Parkes SE,Raafat F,Cameron AH,Marsden HB,Mann JR

更新日期：1991-04-01 00:00:00

abstract：:Mesothelial lesions pose considerable diagnostic challenges not only because benign tumours, reactive proliferations and malignant mesothelioma can mimic one another, but also because the morphological patterns displayed by malignant mesothelioma can simulate a variety of epithelial and non-epithelial malignancies. Im...

journal_title：Journal of clinical pathology

authors： Butnor KJ

更新日期：2006-06-01 00:00:00

abstract：AIMS:Cryptogenic organising pneumonia (COP) and acute fibrinous and organising pneumonia (AFOP) are recognised patterns of organising pneumonia (OP), a condition that resembles pneumonia but is not caused by infection. We have recognised granulomatous organising pneumonia (GOP) to be a similar histopathological entity ...

journal_title：Journal of clinical pathology

authors： Feinstein MB,DeSouza SA,Moreira AL,Stover DE,Heelan RT,Iyriboz TA,Taur Y,Travis WD

更新日期：2015-06-01 00:00:00

abstract：AIMS:To report the clinicopathological characteristics of patients with ocular adnexal marginal zone B cell lymphoma (MZBL) with IgG4-positive plasma cells. METHODS:114 biopsy samples of ocular adnexal MZBLs were analysed. MZBLs with IgG4-positive plasma cells were included when the IgG4:IgG ratio was >40% (IgG4-relat...

journal_title：Journal of clinical pathology

authors： Kubota T,Moritani S,Yoshino T,Nagai H,Terasaki H

更新日期：2010-12-01 00:00:00

abstract：:A polyclonal antiserum, produced in sheep and reactive against purified human leucocyte elastase, has been applied to paraffin sections from a range of human tissues by means of the indirect immunoperoxidase method. Striking and consistent results have been obtained. Normal or inflammatory granulocytes were intensely ...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R,Burnett D

更新日期：1984-10-01 00:00:00

abstract：:Three hundred and ninety eight serum samples from 270 human immunodeficiency virus (HIV) antibody positive asymptomatic homosexual men were tested in the Abbott and Dupont HIV antigen ELISA tests. In the Abbott test 62 (16%) of the sera were positive, according to the manufacturer's instructions, compared with 55 (14%...

journal_title：Journal of clinical pathology

authors： Shanson DC,Brown KE,Goonesekera S,Gazzard B,Coates AR

更新日期：1990-05-01 00:00:00

abstract：AIMS:To investigate the problems involved in undertaking immunohistochemistry (IHC) and nuclear morphometry using Bouin's fixed prostate biopsies. METHODS:Archival Bouin's fixed and formalin fixed, paraffin wax embedded prostatic biopsies were immunostained for three nuclear biomarkers (minichromosome maintenance prot...

journal_title：Journal of clinical pathology

authors： Ananthanarayanan V,Pins MR,Meyer RE,Gann PH

更新日期：2005-03-01 00:00:00

abstract：:A comprehensive neuropathological study was undertaken on 87 children aged between 2 and 15 years with fatal head injuries to identify those features which occurred at the time of head injury (fractured skull, contusions, intracranial haematoma and diffuse axonal injury) and those which were subsequently produced by c...

journal_title：Journal of clinical pathology

authors： Graham DI,Ford I,Adams JH,Doyle D,Lawrence AE,McLellan DR,Ng HK

更新日期：1989-01-01 00:00:00

abstract：:Methods for detecting insulin binding or transporting antibodies are described, involving the use of radioactively labelled insulin (insulin (131)I). These antibodies are detected in a high proportion of patients receiving insulin, particularly those requiring large doses. The protein fractions concerned appear to be ...

journal_title：Journal of clinical pathology

authors： HARRIS-JONES JN,MILLER H,OWEN G

更新日期：1963-03-01 00:00:00

abstract：AIMS:To establish a three dimensional reconstruction of an invasive breast carcinoma using basic laboratory equipment to evaluate and characterise the spatial arrangement of the parenchymal cells of the breast. METHODS:One hundred and twenty eight sequential 4 microm sections (20 microm apart) of the tumour were stain...

journal_title：Journal of clinical pathology

authors： Kurien T,Boyce RW,Paish EC,Ronan J,Maddison J,Rakha EA,Green AR,Ellis IO

更新日期：2005-09-01 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：:Several studies have recently documented the presence of persistently abnormal liver function tests in asymptomatic haemophiliacs. While the aetiology is unknown it is possible that repeated exposure to agents transmitted in blood products may be important. This study has attempted to determine the prevalence of viral...

journal_title：Journal of clinical pathology

authors： McVerry BA,Ross MG,Knowles WA,Voke J

更新日期：1979-04-01 00:00:00

abstract：:Blood cultures drawn from a patient with clinically diagnosed invasive meningococcal disease, who had been previously administered benzylpenicillin, had beta-lactamases added to increase the probability of recovery of the causative organism. The blood cultures subsequently yielded Neisseria meningitidis but direct sus...

journal_title：Journal of clinical pathology

authors： Weightman NC

更新日期：2001-11-01 00:00:00

abstract：:Two cases are described in which clostridial invasion of the liver and spleen was noted at post-mortem examination. In each there was a history of debilitating disease and it is suggested that the infection was consequent upon impaired immunological and cellular defence mechanisms. ...

journal_title：Journal of clinical pathology

authors： ASHLEY DJ

更新日期：1965-03-01 00:00:00

abstract：AIMS:N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been shown to be useful for ruling out heart failure in primary care. In this study, we examined the accuracy of the Cobas h232 point-of-care (POC) instrument in primary care compared with an in-hospital measurement. Furthermore, we investigated the user-fr...

journal_title：Journal of clinical pathology

authors： Hex C,Smeets M,Penders J,Van Hoof V,Verbakel J,Buntinx F,Vaes B

更新日期：2018-06-01 00:00:00

abstract：:Autoinfective strongyloidiasis is often fatal in immunosuppressed patients or in immunocomprised hosts. An interesting case of Strongyloides stercolaris hyperinfection was seen in an immunocompetent patient. This report describes a case of fatal strogyloidiasis in a 79 year old man, who had suffered gastrointestinal d...

journal_title：Journal of clinical pathology

authors： Mayayo E,Gomez-Aracil V,Azua-Blanco J,Azua-Romeo J,Capilla J,Mayayo R

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Oncogenicity of human papillomavirus (HPV) DNA in premalignant and malignant uterine cervical diseases is mainly induced by E6/E7 open reading frame (ORF). The presence of an oncogenic HPV DNA may be a diagnostic marker for the detection of cytologically negative smears. AIMS:To evaluate an original polymer...

journal_title：Journal of clinical pathology

authors： Clavel C,Rihet S,Masure M,Chypre C,Boulanger JC,Quereux C,Birembaut P

更新日期：1998-01-01 00:00:00

abstract：AIMS:Dysfunctional prothrombin residue Arg596 associated mutation has been found to precipitate venous thromboembolism (VTE). In the current study we investigated the prevalence of Arg596 associated mutations in Chinese patients with VTE and explored the functional impact of Arg596Gln mutation on coagulation function i...

journal_title：Journal of clinical pathology

authors： Wu X,Li L,Ding Q,Wang X,Wu F,Wu W

更新日期：2018-07-01 00:00:00

abstract：:These guidelines update the previous UK HER2 testing guidelines and have been formulated to give advice on methodology, interpretation and quality assurance to ensure that HER2 testing results are accurate, reliable and timely with the expansion of testing to all patients with breast cancer at the time of primary diag...

journal_title：Journal of clinical pathology

authors： Walker RA,Bartlett JM,Dowsett M,Ellis IO,Hanby AM,Jasani B,Miller K,Pinder SE

更新日期：2008-07-01 00:00:00

abstract：:Morphometric techniques were applied to cytocentrifuge smears from 27 patients with histologically confirmed follicular non-Hodgkin's lymphoma to determine the usefulness of this method in diagnosis. Analysis of quantitative data confirmed that most subtypes were classified correctly on the basis of the proportion of ...

journal_title：Journal of clinical pathology

authors： Stevens MW,Crowley KS,Fazzalari NL,Woods AE

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVES:As the best characterised cancer/testis antigen family members, melanoma-associated antigens (MAGE) have been reported to be expressed in various malignant tumours. However, the expression pattern of MAGE-A family in lung adenocarcinoma (LAC) specimens and their prognostic and therapeutic significance for pa...

journal_title：Journal of clinical pathology

authors： Sang M,Gu L,Yin D,Liu F,Lian Y,Zhang X,Liu S,Huang W,Wu Y,Shan B

更新日期：2017-06-01 00:00:00

abstract：AIMS:To assess the association between Helicobacter pylori-associated gastritis and HLA-DR antigen (class II antigen) expression. METHODS:Fifty endoscopic gastric biopsy specimens were studied for the presence of H pylori, degree and type of inflammation, and for HLA-DR antigen expression in the epithelium. The cases ...

journal_title：Journal of clinical pathology

authors： Wee A,Teh M,Kang JY

更新日期：1992-01-01 00:00:00

abstract：:A 57 year old woman presented complaining of increasing abdominal swelling of six months duration. A mixed solid cystic left ovarian tumour measuring 24 cm in diameter was excised. Histology showed numerous cysts lined by benign mucinous epithelium blending imperceptibly into borderline clear cell and mucinous areas t...

journal_title：Journal of clinical pathology

authors： Dutt N,Berney DM

更新日期：2000-12-01 00:00:00