Viral exposure and abnormal liver function in haemophilia.

abstract：:These guidelines update the previous UK HER2 testing guidelines and have been formulated to give advice on methodology, interpretation and quality assurance to ensure that HER2 testing results are accurate, reliable and timely with the expansion of testing to all patients with breast cancer at the time of primary diag...

journal_title：Journal of clinical pathology

authors： Walker RA,Bartlett JM,Dowsett M,Ellis IO,Hanby AM,Jasani B,Miller K,Pinder SE

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori associated gastric cancer arises via a multistage process, with atrophic gastritis being the precursor lesion. Helicobacter pylori is typically acquired in childhood, yet little is known of the prevalence of atrophic gastritis in childhood. AIM:To study atrophic gastritis among children ...

journal_title：Journal of clinical pathology

authors： Ricuarte O,Gutierrez O,Cardona H,Kim JG,Graham DY,El-Zimaity HM

更新日期：2005-11-01 00:00:00

abstract：:Attempts to detect hepatitis B antigen in faeces and bile should take into account the degradation and disappearance of the surface antigens in an environment containing proteolytic enzymes in the presence of bile salts as in the intestinal lumen. The cores of the Dane particles are much more stable than the surface a...

journal_title：Journal of clinical pathology

authors： Moodie JW,Stannard LM,Kipps A

更新日期：1974-09-01 00:00:00

abstract：:Isolates of Bacillus cereus from 118 cases, and two maternity unit outbreaks, of non-gastrointestinal infection were grouped on the basis of their estimated probable involvement in the infections from which they were isolated: (i) high probability--48 strains; (ii) intermediate--16 strains; (iii) low--7 strains; (iv) ...

journal_title：Journal of clinical pathology

authors： Turnbull PC,Kramer JM

更新日期：1983-10-01 00:00:00

abstract：AIMS:To assess the possible role of hypoxia in the formation of axonal bulbs. METHODS:Study material comprised sections from 28 brains showing evidence of cerebral hypoxia with no history of head injury, four with a history of head trauma but no evidence of hypoxic change, eight with a history of head trauma and hypox...

journal_title：Journal of clinical pathology

authors： Kaur B,Rutty GN,Timperley WR

更新日期：1999-03-01 00:00:00

abstract：AIMS:To study the incidence, investigation, and management of severe hyponatraemia (serum sodium < 120 mmol/litre) over a period of six months in a district general hospital. METHODS:The laboratory computer was used to identify all inpatients who had a serum sodium concentration of less than 120 mmol/litre over a six ...

journal_title：Journal of clinical pathology

authors： Saeed BO,Beaumont D,Handley GH,Weaver JU

更新日期：2002-12-01 00:00:00

abstract：:Partial myoepithelial differentiation is common in simple epithelial hyperplasia (epitheliosis) of the breast but functional myoepithelial differentiation with basement membrane production is exceedingly rare. A peculiar change of hyaline globules within benign epithelial hyperplasia has been recognised before as "col...

journal_title：Journal of clinical pathology

authors： Wells CA,Wells CW,Yeomans P,Viña M,Jordan S,d'Ardenne AJ

更新日期：1990-11-01 00:00:00

abstract：:When the posture was changed from horizontal to vertical, or the reverse, the alteration in plasma volume and in the levels of haematocrit, haemoglobin, and plasma protein was much greater in patients with oedema or low plasma protein or albumin concentrations ("the pathological group") than in patients without these ...

journal_title：Journal of clinical pathology

authors： FAWCETT JK,WYNN V

更新日期：1960-07-01 00:00:00

abstract：:Tests of iron and folate nutrition have been carried out in early pregnancy and at delivery in 63 Bantu females. Accepted normal values for serum iron, and percentage saturation of transferrin, but not for unsaturated iron-binding capacity, for non-pregnant subjects were found to apply equally well in pregnancy. Conco...

journal_title：Journal of clinical pathology

authors： Metz J,Turchetti L,Combrink B,Krawitz S

更新日期：1966-03-01 00:00:00

abstract：:The discovery of ETS gene fusions as common events in prostate cancer represents a paradigmatic shift in the significance attributed to chromosomal translocations as a key mechanistic player in carcinogenesis. However, these chromosomal fusion events are poorly understood, as their functional significance and therapeu...

journal_title：Journal of clinical pathology

authors： Attard G,Ang JE,Olmos D,de Bono JS

更新日期：2008-08-01 00:00:00

abstract：:A case of squamous cell carcinoma of the terminal ileum with no underlying duplication or inflammatory disorder is described. The neoplasm seemed to have originated from the surface epithelium, invading the wall and metastasising to the regional lymph nodes. The 65 year old patient was free of disease three years afte...

journal_title：Journal of clinical pathology

authors： Platt CC,Haboubi NY,Schofield PF

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:The mitogenic kinin peptides formed by the serine protease, tissue kallikrein (TK1), stimulate the proliferation of tumour cells and, by increasing vascular permeability, enhance metastasis. Oesophageal mucosal epithelial cells are derived from the epithelial cell germ layer, which expresses the kallikrein-k...

journal_title：Journal of clinical pathology

authors： Dlamini Z,Bhoola KD

更新日期：2005-09-01 00:00:00

abstract：:An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment. ...

journal_title：Journal of clinical pathology

authors： Canning DM,Crane RS,Huntsman RG,Yawson GI

更新日期：1972-04-01 00:00:00

abstract：PURPOSE:To investigate p53 and hepatoma-derived growth factor (HDGF) expression and their association with clinicopathological features of Ewing family tumour (EFT). EXPERIMENTAL DESIGN:A total of 108 cases of EFT were retrospectively analysed. p53 and HDGF expression were detected using immunohistochemistry, and the ...

journal_title：Journal of clinical pathology

authors： Yang Y,Zhen T,Zhang F,Dai S,Kang L,Liang Y,Xue L,Han A

更新日期：2014-03-01 00:00:00

abstract：:A case of nodular regenerative hyperplasia (NRH) of the liver is described in association with exposure to the radiographic contrast medium Thorotrast. This is the first case in which the pathological findings have been fully documented. It is suggested that NRH may have developed through Thorotrast induced damage to ...

journal_title：Journal of clinical pathology

authors： Beer TW,Carr NJ,Buxton PJ

更新日期：1998-12-01 00:00:00

abstract：:An inhibitor of plasminogen activator has been identified in human platelets by the technique of sodium dodecyl sulphate polyacrylamide gel electrophoresis and zymography. The inhibitor has a molecular weight of about 40 000 and is distinct from known plasma protease inhibitors. It is associated almost exclusively wit...

journal_title：Journal of clinical pathology

authors： Booth NA,Anderson JA,Bennett B

更新日期：1985-07-01 00:00:00

abstract：:Macroscopic evidence of bruising from human bite marks may be inconclusive and routine histochemical methods of showing extravasated erythrocytes can be unreliable. Leuco patent blue staining, for the presence of peroxidase, Amido black B, a tinctorial staining method for haemoglobin, Perls's reaction for ferric iron ...

journal_title：Journal of clinical pathology

authors： Allison RT,Whittaker DK

更新日期：1990-07-01 00:00:00

abstract：:HeLa 229 cells were infected with genital tract strains of Chlamydia trachomatis. After incubation for varying times the infected cells were fixed and stained with the fluorescent DNA binding dyes Hoechst 33258 or DAPI for comparison with conventional Giemsa stain. Fluorochrome-treated preparations were examined by in...

journal_title：Journal of clinical pathology

authors： Salari SH,Ward ME

更新日期：1979-11-01 00:00:00

abstract：:One hundred prostates from 20 to 40 year old men obtained at necropsy were completely sectioned and studied microscopically. Atypical hyperplasia was found in 10 (20%) of 20-29 year old men and in 12 (24%) of 30-40 year old men. The prostates with atypical hyperplasia had similar weights as those without, and the atyp...

journal_title：Journal of clinical pathology

authors： Brawn PN,Speights VO,Contin JU,Bayardo RJ,Kuhl DL

更新日期：1989-04-01 00:00:00

abstract：:Results of serological investigations on patients with joint pain, arthralgia or polyarthritis were analysed and this information was used to develop a diagnostic algorithm to ensure optimal utilisation of laboratory resources. Accordingly, all cases are now examined for parvovirus IgM, mycoplasma IgM and streptococca...

journal_title：Journal of clinical pathology

authors： Jones JW,Pether JV,Frost RW

更新日期：1995-08-01 00:00:00

abstract：:Two hundred and forty-seven strains of micro-organisms were isolated from the urinary tract of 121 patients with neurological complaints leading to paraplegia. The commonest infecting organism was E. coli and the commonest type of Proteus was P. mirabilis. Infections with more than one type of organism were present in...

journal_title：Journal of clinical pathology

authors： SCOTT TG

更新日期：1960-01-01 00:00:00

abstract：:Apocrine morphology is a common phenomenon encountered in everyday breast pathology practice, and is defined as cuboidal or columnar cells exhibiting abundant eosinophilic granular cytoplasm, prominent apical granules, a low nuclear-cytoplasmic ratio, and round nuclei with pale chromatin and prominent nucleoli. Apocri...

journal_title：Journal of clinical pathology

authors： D'Arcy C,Quinn C

更新日期：2019-01-01 00:00:00

abstract：:An ultrastructural cytochemical study of lysosomal acid phosphatase was performed on leukemic cells in a case of chronic lymphocytic leukaemia of T cell origin (T-CLL). The cells showed inclusion bodies known as parallel tubular arrays, which often lay within acid phosphatase-positive, membrane-bound spaces. This sugg...

journal_title：Journal of clinical pathology

authors： Capron F,PErrot JY,Boucheix C,Reynes M,Tricottet V,Bernadou A,Diebold J

更新日期：1982-02-01 00:00:00

abstract：:The immunofluorescent examination of nasopharyngeal secretions has been compared with conventional cell culture for the diagnosis of respiratory syncytial (RS) virus infection in children under the age of 2 years in Newcastle upon Tyne and Manchester. Two hundred and sixty-eight identifications of RS virus were made b...

journal_title：Journal of clinical pathology

authors： Cradock-Watson JE,McQuillin J,Gardner PS

更新日期：1971-05-01 00:00:00

abstract：AIMS:This is a qualitative study of the perceived learning needs of trainees for graded responsibility in histopathological training in the UK. METHODS:A focus group with trainees and interviews with consultants was carried out. Participants were asked 'What do you perceive are the learning needs of histopathology tra...

journal_title：Journal of clinical pathology

authors： Finall A,Allery L

更新日期：2016-01-01 00:00:00

abstract：:The development and evaluation of a new selective medium for Streptococcus pneumoniae is described. It is shown that the new medium (crystal violet-nalidixic acid-gentamicin agar:CVNG) is highly selective for Strep. pneumoniae in sputum specimens containing other organisms and is also sensitive, being only marginally ...

journal_title：Journal of clinical pathology

authors： Nichols T,Freeman R

更新日期：1980-08-01 00:00:00

abstract：:Eight strains of Moraxella phenylpyruvica have been isolated from clinical material in the United Kingdom, the first to be reported from this country. They were characterized, together with three strains of M. phenylpyruvica of the National Collection of Type Cultures (NCTC), and compared with NCTC strains of eight ot...

journal_title：Journal of clinical pathology

authors： Snell JJ,Hill LR,Lapage SP

更新日期：1972-11-01 00:00:00

abstract：:A quantitative method of estimating heparin co-factor in terms of percentage activity is presented. The activity in sera from 75 normal subjects varied little from 100%. Low results were obtained in sera from 50 cases of varying types of malignancy. ...

journal_title：Journal of clinical pathology

authors： TEMPERLEY IJ

更新日期：1963-03-01 00:00:00

abstract：AIMS:Personalised breast cancer therapy requires pathological characterisation of tumours. The proliferative index, based on Ki67, is pivotal, but a standard method has not been established. Here we look for an easy and practical way to evaluate Ki67. METHODS:Immunohistochemical staining of estrogen receptors, progest...

journal_title：Journal of clinical pathology

authors： Hida AI,Bando K,Sugita A,Maeda T,Ueda N,Matsukage S,Nakanishi M,Kito K,Miyazaki T,Ohtsuki Y,Oshiro Y,Inoue H,Kawaguchi H,Yamashita N,Aogi K,Moriya T

更新日期：2015-05-01 00:00:00

abstract：:The hepatic and splenic storage iron, including the relative distribution between ferritin and haemosiderin, was estimated in 130 necropsies including normal accident cases and cases with a variety of diseases. The storage iron was also examined histochemically. It was found that in the normal subjects, on the average...

journal_title：Journal of clinical pathology

authors： Morgan EH,Walters MN

更新日期：1963-03-01 00:00:00