The estimation of heparin co-factor in serum.

abstract：:The clinical and pathological features of a case of malakoplakia of the adrenal gland occurring in a woman with Escherichia coli infection are described. This lesion mimicked a neoplasm, the true diagnosis only being revealed by histological examination. The light and electron microscopic features are described and it...

journal_title：Journal of clinical pathology

authors： Benjamin E,Fox H

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVES:To determine whether antibiotics are prescribed appropriately for acute tonsillitis in an emergency department (ED). METHODS:Cross-sectional observational study in large district general hospital in London. Patients diagnosed and coded with 'acute tonsillitis' in the ED over a 3-month period in 2015. Medica...

journal_title：Journal of clinical pathology

authors： Kanji K,Saatci D,Rao GG,Khanna P,Bassett P,Williams B,Khan M

更新日期：2016-09-01 00:00:00

abstract：:A comprehensive neuropathological study was undertaken on 87 children aged between 2 and 15 years with fatal head injuries to identify those features which occurred at the time of head injury (fractured skull, contusions, intracranial haematoma and diffuse axonal injury) and those which were subsequently produced by c...

journal_title：Journal of clinical pathology

authors： Graham DI,Ford I,Adams JH,Doyle D,Lawrence AE,McLellan DR,Ng HK

更新日期：1989-01-01 00:00:00

abstract：:Of the first 166 heart and 15 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 162 were investigated for cytomegalovirus (CMV) infection by serological methods. Altogether, 73 (45%) developed CMV infection after transplantation: 30 (18.5%...

journal_title：Journal of clinical pathology

authors： Wreghitt TG,Hakim M,Gray JJ,Kucia S,Wallwork J,English TA

更新日期：1988-06-01 00:00:00

abstract：AIMS:To test whether a hypoacidic environment may potentially "stress" Helicobacter pylori DNA, encouraging the emergence of strain variation. METHODS:This hypothesis was tested by inducing prolonged hypoacidity with omeprazole, a potent antisecretory drug. The genomic DNA of H pylori was studied by electrophoretic se...

journal_title：Journal of clinical pathology

authors： Fraser AG,Bickley J,Owen RJ,Pounder RE

更新日期：1992-12-01 00:00:00

abstract：AIMS:Because sentinel lymph node (SLN) biopsy for breast cancer has become well established, one of the challenges now is to determine which patients require a completion axillary dissection following a positive SLN biopsy. METHODS:A prospective database of patients who underwent SLN biopsy for invasive breast cancer ...

journal_title：Journal of clinical pathology

authors： Fleming FJ,Kavanagh D,Crotty TB,Quinn CM,McDermott EW,O'Higgins N,Hill AD

更新日期：2004-01-01 00:00:00

abstract：AIMS:EGFR tyrosine kinase inhibitors (TKIs) are first-line molecularly targeted therapies in patients with advanced non-small cell lung cancer (NSCLC) who carry sensitising EGFR mutations, due to its superior survival outcomes compared with conventional chemotherapy regimens. In this study, we sought to identify clinic...

journal_title：Journal of clinical pathology

authors： Ng IK,Kumarakulasinghe NB,Syn NL,Soo RA

更新日期：2021-02-01 00:00:00

abstract：:Laboratory studies on clotrimazole showed that it had marked activity in vitro against all the Candida spp. and Cryptococcus spp. tested, against almost all strains of dermatophytes, and against Aspergillus spp and other fungal genera responsible for systemic mycoses; it had limited activity towards Gram-positive bact...

journal_title：Journal of clinical pathology

authors： Holt RJ,Newman RL

更新日期：1972-12-01 00:00:00

abstract：:The biochemical classification of the Klebsiella proposed by Cowan, Steel, Shaw, and Duguid (1960) has been applied to 50 strains isolated as the pure or predominant growth from sputum, and Klebsiella species have been correlated with the severity of the chest infection in the patient. A modification in nomenclature i...

journal_title：Journal of clinical pathology

authors： FOSTER WD,BRAGG J

更新日期：1962-09-01 00:00:00

abstract：:The nitroblue tetrazolium (NBT) test has been evaluated as a means of differentiating episodes of infection and rejection in 10 cadaver kidney transplant recipients. Normal NBT values were observed during all 11 episodes of acute rejection. A significant elevation of the NBT score was encountered in six of eight episo...

journal_title：Journal of clinical pathology

authors： Gordon AM,Briggs JD,Bell PR

更新日期：1974-09-01 00:00:00

abstract：:In colonic biopsies of 33 patients with acute colitis caused by campylobacter, salmonella, or shigella immunoglobulin containing cells were determined quantitatively using an indirect immunoperoxidase technique and morphometry with a graphic tablet. The findings were compared with those of 10 patients without histolog...

journal_title：Journal of clinical pathology

authors： van Spreeuwel JP,Lindeman J,Meijer CJ

更新日期：1985-07-01 00:00:00

abstract：:Performance of CHROMagar Acinetobacter was assessed for the selective isolation and identification of Acinetobacter baumannii. The medium was effective in suppressing the growth of other Gram-positive and Gram-negative species while the addition of KPC supplement ensured growth of only carbapenem resistant A baumannii...

journal_title：Journal of clinical pathology

authors： Wareham DW,Gordon NC

更新日期：2011-02-01 00:00:00

abstract：:Myelomatosis was diagnosed in a 64 year old man on the basis of a serum paraprotein band (type IgG lambda, 42 g/l), plasma cell infiltration of bone marrow, and multiple lytic lesions evident on skull x ray picture. Blood specimens taken into plain glass tubes showed bulky gelatinous clot formation with minimal clot r...

journal_title：Journal of clinical pathology

authors： O'Kane MJ,Wisdom GB,Desai ZR,Archbold GP

更新日期：1994-03-01 00:00:00

abstract：:Antibodies against alpha smooth muscle actin (ASMA) and S100 protein were applied to paraffin wax embedded sections from 40 salivary gland tumours and seven normal salivary glands. The results indicate that ASMA is useful in the diagnosis of epithelial-myoepithelial carcinoma, but is otherwise only of limited use in d...

journal_title：Journal of clinical pathology

authors： Jones H,Moshtael F,Simpson RH

更新日期：1992-10-01 00:00:00

abstract：:An elution technique is described which gives eluates at least as potent as previously described methods. Elution can be completed in only 15 minutes. The method, a modification of that of Vos and Kelsall, is simple to carry out and requires the minimum of equipment. Studies have shown that the coating antibody is alm...

journal_title：Journal of clinical pathology

authors： RUBIN H

更新日期：1963-01-01 00:00:00

abstract：AIMS:The development of a technique for simultaneous in situ hybridisation for native mRNA and conventional immunofluorescence for cytoplasmic antigens in routine pathology specimens. METHODS:Cocktails of synthetic deoxyoligonucleotides coding for immunoglobulin J chain and kappa light chain were 3' end labelled enzym...

journal_title：Journal of clinical pathology

authors： Harper SJ,Pringle JH,Gillies A,Allen AC,Layward L,Feehally J,Lauder I

更新日期：1992-02-01 00:00:00

abstract：:Eosinophil polymorphonuclear leucocytes (polymorphs) were counted in 45 specimens from patients with Hodgkin's disease and five specimens from patients with reactive follicular hyperplasia. The use of chlorazol fast pink BK, a little known stain for eosinophil polymorphs, combined with image analysis facilitated rapid...

journal_title：Journal of clinical pathology

authors： Fuggle WJ,Crocker J,Smith PJ

更新日期：1984-03-01 00:00:00

abstract：:Splenic pathology was analysed in 73 patients with immune thrombocytopenic purpura who underwent splenectomy for bleeding that had been resistant to adrenocorticosteroids. The mean splenic weight was 100 g. The only notable macroscopic feature was the prominence of Malpighian corpuscles in 15 cases. Microscopic examin...

journal_title：Journal of clinical pathology

authors： Hayes MM,Jacobs P,Wood L,Dent DM

更新日期：1985-09-01 00:00:00

abstract：:Phyllodes tumours (PTs) of the breast are true biphasic neoplasms within which interactions between the epithelium and stroma are critical for tumour development and progression. Despite numerous studies reporting the results of ancillary marker investigations in PTs, the current histological grading systems remain un...

journal_title：Journal of clinical pathology

authors： Karim RZ,O'Toole SA,Scolyer RA,Cooper CL,Chan B,Selinger C,Yu B,Carmalt H,Mak C,Tse GM,Tan PH,Putti TC,Lee CS

更新日期：2013-06-01 00:00:00

abstract：:Sera can produce nuclear or perinuclear immunofluorescence staining in neutrophils which may be caused by antibodies with differing antigenic specificities. These include perinuclear antineutrophil cytoplasmic antibodies (P-ANCA), granulocyte specific antinuclear antibody (GS-ANA), and antinuclear antibody (ANA). Ther...

journal_title：Journal of clinical pathology

authors： Chowdhury SM,Broomhead V,Spickett GP,Wilkinson R

更新日期：1999-06-01 00:00:00

abstract：AIM:The earlier detection of breast cancer through mammographic screening has resulted in a shift in stage distribution with patients who are node-positive tending to present with a lower number of positive lymph nodes (LN). This study aims to assess the prognostic value of absolute number of positive nodes in the pN1 ...

journal_title：Journal of clinical pathology

authors： Rakha EA,Morgan D,Macmillan D

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Thymidine phosphorylase (TP) is the key enzyme for capecitabine activation in tumour cells. AIMS:To examine whether TP expression in tumour cells and stroma is predictive of the tumour response to capecitabine plus docetaxel chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). METHODS...

journal_title：Journal of clinical pathology

authors： Han JY,Hong EK,Lee SY,Yoon SM,Lee DH,Lee JS

更新日期：2005-06-01 00:00:00

abstract：:A case of a 20 year old Japanese woman who developed thyroid cancer exhibiting unusual cribriform structures while being followed up for familial adenomatous polyposis/Gardner's syndrome is reported. The patient presented with osteomas, pigmented retinal lesions, and adenomas of the duodenum and the papilla of Vater, ...

journal_title：Journal of clinical pathology

authors： Hizawa K,Iida M,Yao T,Aoyagi K,Oohata Y,Mibu R,Yamasaki K,Hirata T,Fujishima M

更新日期：1996-07-01 00:00:00

abstract：:This paper illustrates a simple method of necropsy dissection of the abdominal organs after abdominal surgery. The organs are removed in one block as per the method described by Letulle. A retroperitoneal approach is then used. Structures are dissected away in a series of layers using the vasculature for guidance. Thi...

journal_title：Journal of clinical pathology

authors： Culora GA,Roche WR

更新日期：1996-09-01 00:00:00

abstract：AIM:To establish whether infection with Epstein-Barr virus (EBV) contributed to the development of coronary artery lesions in a six year old child with an aneurysm and stenoses of the coronary arteries and suspected Kawasaki disease. METHODS:Postmortem paraffin wax sections of the coronary artery and myocardium were e...

journal_title：Journal of clinical pathology

authors： Culora GA,Moore IE

更新日期：1997-02-01 00:00:00

abstract：:Immunoreactive plasminogen activators were studied in tissue sections using a peroxidase method and monospecific antibodies to tissue plasminogen activator produced by a melanoma. Tissue plasminogen activator reactivity was found in skin melanomas and in endothelial and smooth muscle cells of arteries and veins. Vesse...

journal_title：Journal of clinical pathology

authors： Larsson A,Astedt B

更新日期：1985-02-01 00:00:00

abstract：:Malignant extrarenal rhabdoid tumour (MERT) of the gastrointestinal tract is rarely reported in the literature. This report describes the clinical and pathological features of a malignant rhabdoid tumour of the oesophagus in a Chinese man. Ivor-Lewis oesophagectomy had been performed. The tumour behaved aggressively a...

journal_title：Journal of clinical pathology

authors： Ng WC,Leong HT,Ma KF,Yip WL,Suen WM

更新日期：2003-09-01 00:00:00

abstract：AIMS:To determine whether Ki-67 immunoexpression in penile squamous cell carcinoma (PSCC) has a prognostic value and correlates with lymph node metastasis, human papillomavirus (HPV) infection and patient survival. METHODS:148 formalin-fixed paraffin-embedded PSCC samples were tissue-microarrayed, including 97 usual-t...

journal_title：Journal of clinical pathology

authors： Stankiewicz E,Ng M,Cuzick J,Mesher D,Watkin N,Lam W,Corbishley C,Berney DM

更新日期：2012-06-01 00:00:00

abstract：:One hundred cases of transitional cell carcinoma of the bladder were studied to determine whether squamous metaplasia and other histological features within the bladder can be of value in predicting outcome of treatment with radiotherapy. Sixty cases showed the changes of squamous metaplasia, and of this group 46 (78%...

journal_title：Journal of clinical pathology

authors： Martin JE,Jenkins BJ,Zuk RJ,Blandy JP,Baithun SI

更新日期：1989-03-01 00:00:00

abstract：AIM:To determine the frequency, pattern and distribution of stromal keratin expression in phyllodes tumours if any, which may impact diagnostic approaches. METHODS:The clinicopathological features of 109 phyllodes tumours comprising 70 (64.2%) benign, 30 (27.5%) borderline and nine (8.3%) malignant grades were evaluat...

journal_title：Journal of clinical pathology

authors： Chia Y,Thike AA,Cheok PY,Yong-Zheng Chong L,Man-Kit Tse G,Tan PH

更新日期：2012-04-01 00:00:00