Factors affecting metastases to non-sentinel lymph nodes in breast cancer.

abstract：AIMS:To determine whether the monoclonal antibody (MoAb) 83D4, previously shown to be highly specific for carcinoma cells, can be used as an immunocytological marker to discriminate between benign and malignant cells in serous effusions; and to test for a correlation between expression of the antigen reacting with MoAb...

journal_title：Journal of clinical pathology

authors： Beuzelin-Yvraut M,Bourguignat A,Phillips E,Roseto A,Osinaga E

更新日期：1995-05-01 00:00:00

abstract：AIMS:To investigate the correlation between centrally assessed human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) results and response to treatment of patients with metastatic breast cancer enrolled in a first-line, phase II, open-label, 3-weekly tra...

journal_title：Journal of clinical pathology

authors： Hofmann M,Stoss O,Gaiser T,Kneitz H,Heinmöller P,Gutjahr T,Kaufmann M,Henkel T,Rüschoff J

更新日期：2008-01-01 00:00:00

abstract：:Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal ep...

journal_title：Journal of clinical pathology

authors： Jenkins D,Stephenson PM,Scott BB

更新日期：1985-03-01 00:00:00

abstract：:The use of the dye calcon (1-(2 hydroxy-1-naphthylazo)-2-naphthol-4 sulphonic acid) for the estimation of calcium using E.D.T.A. and a commercial photoelectric titrimeter is described. The interfering effects of magnesium and phosphate have been overcome. The method has been extended to estimations on biological mater...

journal_title：Journal of clinical pathology

authors： BOWDEN CH,PATSTON VJ

更新日期：1963-01-01 00:00:00

abstract：:Components of the blood fibrinolytic system were measured in 43 patients with leukaemia. Increased fibrinolytic activity, indicated by a reduced plasma plasminogen level, was found in 14 patients. The combination of severe thrombocytopenia and increased fibrinolysis appeared to be a determinant in the production of a ...

journal_title：Journal of clinical pathology

authors： Ogston D,McAndrew GM,Ogston CM

更新日期：1968-03-01 00:00:00

abstract：:The performance of coagulometers in the National Quality Assessment Scheme (NEQAS) surveys of the prothrombin time conducted between 1986 and 1987 was reviewed. There were sufficient data for analysis for eight types of coagulometer used with a single type of thromboplastin reagent and one instrument with an alternati...

journal_title：Journal of clinical pathology

authors： Poller L,Thomson JM,Taberner DA

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF) is the most common skin lymphoid neoplasm. In initial stages, differential diagnosis of MF from other benign dermal lymphoid infiltrates (BDLI) may be impossible on morphological basis alone. In previous studies, only deletion of CD7 in MF proved to be of diagnostic help, but not the r...

journal_title：Journal of clinical pathology

authors： Lira M,Schenka AA,Magna LA,Cotta AC,Cintra ML,de Souza EM,Brousset P,Vassallo J

更新日期：2008-02-01 00:00:00

abstract：:A radioimmunoassay for human growth hormone using activated charcoal is described and its precision, accuracy, and sensitivity are defined. Results are presented for growth hormone measurements in plasma obtained during hypoglycaemia induced with insulin in patients of short stature and during glucose tolerance tests ...

journal_title：Journal of clinical pathology

authors： Thomas FJ,Lloyd HM,Thomas MJ

更新日期：1972-09-01 00:00:00

abstract：:Sera obtained from 34 men with Chlamydia trachomatis positive non-gonococcal urethritis, 34 men with C trachomatis negative non-gonococcal urethritis, 42 women with acute salpingitis, 38 healthy women, and 34 healthy men were studied for the presence of specific serum C trachomatis IgA and IgG antibodies. Serological ...

journal_title：Journal of clinical pathology

authors： Cevenini R,Sarov I,Rumpianesi F,Donati M,Melega C,Varotti C,La Placa M

更新日期：1984-06-01 00:00:00

abstract：:A patient with megaloblastic anaemia due to nutritional folate deficiency is described. Partial villous atrophy and malabsorption of xylose showed progressive improvement to normal with folic acid therapy. ...

journal_title：Journal of clinical pathology

authors： Dawson DW

更新日期：1971-03-01 00:00:00

abstract：:The separation of mesothelial hyperplasia from early malignant mesothelioma remains one of the most difficult problems in histopathology. Inconclusive cases are termed "atypical mesothelial hyperplasia" and treated expectantly. A 49 year old male pipeline engineer was diagnosed as having atypical mesothelial hyperplas...

journal_title：Journal of clinical pathology

authors： Scurry J,Duggan MA

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Clinical outcome in patients with diffuse large B cell lymphomas (DLBCL) is highly variable and poorly predictable. Microarray studies showed that patients with DLBCL with a germinal centre B cell-like (GCB) phenotype have a better prognosis than those with an activated B cell-like (ABC) phenotype. The BMI1 ...

journal_title：Journal of clinical pathology

authors： van Galen JC,Muris JJ,Oudejans JJ,Vos W,Giroth CP,Ossenkoppele GJ,Otte AP,Raaphorst FM,Meijer CJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Cytokeratin immunohistochemistry (IHC) reveals a higher rate of occult lymph node metastases among lobular carcinomas than among ductal breast cancers. IHC is widely used but is seldom recommended for the evaluation of sentinel lymph nodes in breast cancer patients. OBJECTIVE:To assess the value of cytokera...

journal_title：Journal of clinical pathology

authors： Cserni G,Bianchi S,Vezzosi V,Peterse H,Sapino A,Arisio R,Reiner-Concin A,Regitnig P,Bellocq JP,Marin C,Bori R,Penuela JM,Iturriagagoitia AC

更新日期：2006-05-01 00:00:00

abstract：:A 51 year old woman presented with rectal bleeding from a mass lying just above the dentate line. Multiple biopsies were taken before the diagnosis of a benign lymphoid polyp was made. This is a rare condition that more commonly presents in children and poses a diagnostic challenge. ...

journal_title：Journal of clinical pathology

authors： Lloyd J,Darzi A,Teare J,Goldin RD

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:Cellular blue naevi (CBN) measure 1-2 cm in diameter and affect the dermis, occasionally extending into the subcutaneous fat. The case of a 14-year-old boy with a giant CBN (GCBN) involving the right half of the face, the jugal mucosa and the lower eyelid with a tumour that had infiltrated the bone and the...

journal_title：Journal of clinical pathology

authors： Bittencourt AL,Monteiro DA,De Pretto OJ

更新日期：2007-01-01 00:00:00

abstract：:A unique case of a metastatic non-desmoplastic sarcomatoid malignant melanoma in an axillary lymph node showing smooth muscle differentiation in a 54 year old woman is described. The tumour cells exhibited alpha-smooth muscle actin, HHF-35 and desmin positivity but were negative for S100 protein and HMB-45. Ultrastruc...

journal_title：Journal of clinical pathology

authors： Banerjee SS,Bishop PW,Nicholson CM,Eyden BP

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVES:As the best characterised cancer/testis antigen family members, melanoma-associated antigens (MAGE) have been reported to be expressed in various malignant tumours. However, the expression pattern of MAGE-A family in lung adenocarcinoma (LAC) specimens and their prognostic and therapeutic significance for pa...

journal_title：Journal of clinical pathology

authors： Sang M,Gu L,Yin D,Liu F,Lian Y,Zhang X,Liu S,Huang W,Wu Y,Shan B

更新日期：2017-06-01 00:00:00

abstract：:As patients with multiple myeloma (MM) have a variable clinical course, predictive markers would help determine the appropriate treatment strategy. Clinical staging is commonly used to predict outcome, but tumour marker expression and the underlying genetic changes are increasingly used to assess the biological aggres...

journal_title：Journal of clinical pathology

authors： Yeung J,Chang H

更新日期：2008-07-01 00:00:00

abstract：:A miniaturised method for the identification of anaerobic bacteria is described which employs microtitre fermentation tests, a spot indole test and a nitrate reduction disc test. The results obtained are directly comparable with those produced by a standard conventional method in use at present. ...

journal_title：Journal of clinical pathology

authors： Levett PN

更新日期：1984-01-01 00:00:00

abstract：:The clinical, haematological, morphological and histological features of a series of 22 patients presenting with splenic lymphoma with circulating villous lymphocytes were assessed and compared with those of patients with other forms of chronic B cell leukaemia in an attempt to differentiate this condition from hairy ...

journal_title：Journal of clinical pathology

authors： Melo JV,Hegde U,Parreira A,Thompson I,Lampert IA,Catovsky D

更新日期：1987-06-01 00:00:00

abstract：AIMS:To study the pathogenicity and virulence characteristics of Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus sapro-phyticus. METHODS:BALB/c mice were challenged intraperitoneally with graded doses of three strains belonging to each species. LD50s were measured for each strain. Haemolysi...

journal_title：Journal of clinical pathology

authors： Molnàr C,Hevessy Z,Rozgonyi F,Gemmell CG

更新日期：1994-08-01 00:00:00

abstract：:A correlative clinical and Hemalog D study of 80 cases of chronic lymphocytic leukaemia (CLL) was performed and the results compared with those in other lymphoproliferative disorders affecting the blood (eight cases of hairy-cell leukaemia, HCL; three cases of prolymphocytic leukaemia, PLL: two cases of lymphoplasmacy...

journal_title：Journal of clinical pathology

authors： Patterson KG,Goldstone AH,Richards JD,Cawley JC

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Venous invasion (VI) is an important prognosis predictor after colorectal carcinoma (CRC) resection, enabling more accurate staging and influencing postoperative management. AIMS:To assess/compare various tissue block types (perpendicular, tangential, across mesentery (AM), from major vessels or lymph nodes...

journal_title：Journal of clinical pathology

authors： Sternberg A,Mizrahi A,Amar M,Groisman G

更新日期：2006-02-01 00:00:00

abstract：AIMS:The histopathological diagnosis of low-grade dysplasia (LGD) in Barrett's oesophagus (BO) is associated with poor interobserver agreement and guidelines dictate expert review. To facilitate nationwide expert review in the Netherlands, a web-based digital review panel has been set up, which currently consists of ei...

journal_title：Journal of clinical pathology

authors： Klaver E,van der Wel M,Duits L,Pouw R,Seldenrijk K,Offerhaus J,Visser M,Ten Kate F,Biermann K,Brosens L,Doukas M,Huysentruyt C,Karrenbeld A,Kats-Ugurlu G,van der Laan J,van Lijnschoten I,Moll F,Ooms A,Tijssen J,Meij

更新日期：2021-01-01 00:00:00

abstract：:The routine estimation of large numbers of serum folic acid and vitamin B(12) levels using the Baird and Tatlock(1) Analmatic clinical system is described and the method evaluated.Precision, accuracy, and carryover are shown to be at acceptable levels, and the advantages and disadvantages of the use of the system are ...

journal_title：Journal of clinical pathology

authors： Colvin G,Gibson GL,Neill DW

更新日期：1971-02-01 00:00:00

abstract：:Ten patients with severe megaloblastic anaemia were studied to investigate whether the causative metabolic defects might predispose them to lactic or other acidosis. One patient had compensated acidosis with hyperlactataemia before treatment but there were obvious causes other than anaemia. No other patient developed ...

journal_title：Journal of clinical pathology

authors： Franklin IM,Kernoff PB,Isherwood D,Leek J,Morgan DB

更新日期：1982-09-01 00:00:00

abstract：:Macroscopic evidence of bruising from human bite marks may be inconclusive and routine histochemical methods of showing extravasated erythrocytes can be unreliable. Leuco patent blue staining, for the presence of peroxidase, Amido black B, a tinctorial staining method for haemoglobin, Perls's reaction for ferric iron ...

journal_title：Journal of clinical pathology

authors： Allison RT,Whittaker DK

更新日期：1990-07-01 00:00:00

abstract：:In a study of a group of 325 blood donors between the ages of 18 and 65 years, the total leucocyte and polymorph counts of the females aged 50 to 65 years were found to be significantly lower than those of the corresponding group of male donors. In the whole series of female donors, there were significantly lower tota...

journal_title：Journal of clinical pathology

authors： Allan RN,Alexander MK

更新日期：1968-11-01 00:00:00

abstract：BACKGROUND:RCAS1 (receptor binding cancer antigen expressed on SiSo cells) is a tumour associated antigen. It is involved in immune evasion by tumour cells, by binding to receptors on cells involved in the immune response, such as T cells and natural killer cells, and inducing apoptosis. High expression of RCAS1 has be...

journal_title：Journal of clinical pathology

authors： Leelawat K,Watanabe T,Nakajima M,Tujinda S,Suthipintawong C,Leardkamolkarn V

更新日期：2003-10-01 00:00:00

abstract：AIMS:To detect cells bearing BRAF mutations in colorectal tumour samples and peritoneal washings, using a mismatch ligation assay (MLA). METHODS:DNA from 46 colorectal tumours was studied. Part of exon 15 of the BRAF gene was amplified using the polymerase chain reaction, and T-->A mutations at codon 600 were detected...

journal_title：Journal of clinical pathology

authors： Busby K,Morris A

更新日期：2005-04-01 00:00:00