Effect of automation on prothrombin time test in NEQAS surveys.

abstract：AIM:To ascertain the views of Scottish hospital laboratory users on aspects of regional and supraregional biochemical services offered by the Institute of Biochemistry at Glasgow Royal Infirmary. METHODS:A questionnaire was circulated asking questions or inviting opinions under various headings, including current patt...

journal_title：Journal of clinical pathology

authors： Murphy MJ,Dryburgh FJ,Shepherd J

更新日期：1994-05-01 00:00:00

abstract：AIMS:To develop a rapid, sensitive, and specific non-isotopic in situ hybridisation (NISH) procedure for the detection of Epstein-Barr virus in formalin fixed, paraffin wax embedded tissues. METHODS:Two low molecular weight RNAs, designated EBER-1 and EBER-2 (Epstein-Barr encoded RNA), were used: cells latently infect...

journal_title：Journal of clinical pathology

authors： Khan G,Coates PJ,Kangro HO,Slavin G

更新日期：1992-07-01 00:00:00

abstract：:This review surveys the staging systems used for the classification of colorectal carcinomas, including the TNM system, and focuses on the assessment of the nodal stage of the disease. It reviews the quantitative requirements for a regional metastatic work up, and some qualitative features of lymph nodes that may help...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：2003-05-01 00:00:00

abstract：:Seven commercially available screening tests for rheumatoid factor and two quantitative tests have been compared with the standard Rose-Waaler test in a series of 477 sera from patients with various joint diseases. Markedly different results were obtained, and on the basis of our findings suggestions are made as to wh...

journal_title：Journal of clinical pathology

authors： MacSween RN,Hughes H,Breen C,Kitchen P,Cathcart B,Buchanan WW

更新日期：1974-05-01 00:00:00

abstract：:One hundred and seventyone antenatal patients were examined for the presence of ;large colony' mycoplasmas in the vagina, and for complement-fixing antibody to Mycoplasma hominis. In 25 patients the findings before and after delivery were compared. In patients from whom M. hominis was grown, antibody was twice as comm...

journal_title：Journal of clinical pathology

authors： Jones DM

更新日期：1967-07-01 00:00:00

abstract：:Cyclospora cayetanensis is a cause of prolonged diarrhoea, mainly in travellers. Laboratory diagnosis may be achieved by a number of methods such as the staining of faecal smears by the modified Ziehl-Neelsen (ZN) technique. Safer methods using this technique have been described for the staining of acid fast bacilli a...

journal_title：Journal of clinical pathology

authors： Clarke SC,McIntyre M

更新日期：1996-06-01 00:00:00

abstract：:In two cases of infected total hip replacements, Peptococcus magnus was isolated in pure culture from the implant when it was removed. Fluorescent antibody and ELISA studies have shown that both patients developed an antibody response to this anaerobic coccus soon after the replacement operation. These results suggest...

journal_title：Journal of clinical pathology

authors： Taylor AG,Fincham WJ,Golding MA,Cook J

更新日期：1979-01-01 00:00:00

abstract：AIMS:To determine important factors influencing recurrence after local excision of duct carcinoma in situ (DCIS) of the breast. MATERIALS AND METHODS:The extent (size) in millimetres, classification (by cytonuclear grade (NHSBSP system), by extent of necrosis, and by the Van Nuys system), and excision margins of 115 c...

journal_title：Journal of clinical pathology

authors： Douglas-Jones AG,Logan J,Morgan JM,Johnson R,Williams R

更新日期：2002-08-01 00:00:00

abstract：:A new staining method was developed for the detection of inclusions of Chlamydia psittaci and Chlamydia trachomatis inclusions in cell cultures. Using a combination of methyl green and neutral red stains and washing at pH 5.0, inclusions were stained red while cell cytoplasm was pale pink and cell nuclei were pale gre...

journal_title：Journal of clinical pathology

authors： Woodland RM,Malam J,Darougar S

更新日期：1982-06-01 00:00:00

abstract：:The air of three hospital wards was examined frequently for staphylococci for a period of nearly four years using slit samplers. ;Broadcasts' of staphylococci into the air were observed with the air count rising well above the mean of 0.2 staphylococcal particle per cubic foot and these broadcasts often appeared to be...

journal_title：Journal of clinical pathology

authors： Noble WC

更新日期：1962-11-01 00:00:00

abstract：:Apocrine morphology is a common phenomenon encountered in everyday breast pathology practice, and is defined as cuboidal or columnar cells exhibiting abundant eosinophilic granular cytoplasm, prominent apical granules, a low nuclear-cytoplasmic ratio, and round nuclei with pale chromatin and prominent nucleoli. Apocri...

journal_title：Journal of clinical pathology

authors： D'Arcy C,Quinn C

更新日期：2019-01-01 00:00:00

abstract：AIMS:Soft tissue tumours are a heterogeneous group of neoplasms that can arise at almost every anatomical site. As they often show similar clinical and radiological findings, histology is the definitive diagnostic method and it is crucial that the surgical pathology report contains accurate, useful information for mana...

journal_title：Journal of clinical pathology

authors： Shah C,Wang J,Mubako T,Fisher C,Thway K

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The TNM classification for renal cell cancer (RCC) should accurately predict and assign prognostic information for patients. In this study the recent 2010 revision to the TNM classification was compared with the previous 2002 classification with regard to survival outcomes. METHODS:All patients having radic...

journal_title：Journal of clinical pathology

authors： Veeratterapillay R,Simren R,El-Sherif A,Johnson MI,Soomro N,Heer R

更新日期：2012-04-01 00:00:00

abstract：AIMS:The JAK2 V617F mutation is highly recurrent in many of the myeloproliferative neoplasms, a molecular variant that can be easily detected using sensitive and minimally invasive techniques. Given the ease of JAK2 V617F testing, this test may be improperly requested for the purposes of patient 'screening' and to opti...

journal_title：Journal of clinical pathology

authors： Mahe E,Pedersen KM,Çolak Y,Bojesen SE,Lynch T,Sinclair G,Khan F,Shabani-Rad MT

更新日期：2019-02-01 00:00:00

abstract：:Patients with congenital lung cysts are at increased risk of developing carcinoma, but the mechanisms concerned are not clear. The case of a young adult who developed a bronchioloalveolar carcinoma associated with a cystic congenital adenomatoid malformation is reported. The adjacent lung showed an unusual intra-alveo...

journal_title：Journal of clinical pathology

authors： Sheffield EA,Addis BJ,Corrin B,McCabe MM

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The disorders associated with metabolic syndrome (MS) can lead to renal disease. IgA nephropathy is the most common form of glomerulonephritis, and many patients with this disorder progress to renal failure. AIMS:To identify the effect of MS on IgA nephropathy by retrospectively comparing patients who had I...

journal_title：Journal of clinical pathology

authors： Wang L,Zhang Y,Chen S,Chen J,Zhuang Y,Chen J

更新日期：2010-08-01 00:00:00

abstract：:A method is described for the quantitative separation of radioactive bile acids and neutral sterols in human faeces on a potassium hydroxide-treated silicic acid column. Results obtained with faecal extracts containing metabolites derived from radioactive cholesterol, cholic acid, and chenodeoxycholic acid show that t...

journal_title：Journal of clinical pathology

authors： LEWIS B,MYANT NB

更新日期：1965-01-01 00:00:00

abstract：AIMS:To investigate the immunohistochemical expression of p53 protein in non-Hodgkin's lymphomas (NHL) and its relation to that of c-myc p62 oncoprotein and proliferating cell nuclear antigen (PCNA). METHODS:Paraffin wax embedded tissue from 90 non-Hodgkin's lymphomas (72 B cell and 18 T cell) was stained immunohistoc...

journal_title：Journal of clinical pathology

authors： Korkolopoulou P,Oates J,Kittas C,Crocker J

更新日期：1994-01-01 00:00:00

abstract：:Bone marrow aspirates and biopsy specimens were taken at diagnosis from 51 patients with acute myeloid leukaemia (AML). The diagnosis was based on morphological and cytochemical analyses, and the leukaemias were classified by FAB criteria. A considerable difference was observed between the results of bone marrow aspir...

journal_title：Journal of clinical pathology

authors： Islam A,Frisch B,Henderson ES

更新日期：1989-03-01 00:00:00

abstract：:If native or heparinized blood is passed slowly through a column of glass beads at room temperature, the number of platelets removed from the initial drop emerging from the column is less than that removed from the final drop. At 4 degrees C. this difference disappears. If the blood is passed rapidly through such colu...

journal_title：Journal of clinical pathology

authors： O'Brien JR,Heywood JB

更新日期：1967-01-01 00:00:00

abstract：AIMS:Pim-1 is a serine/threonine kinase that has been shown to play an integral role in the development of a number of human cancers, such as haematolymphoid malignancies. Recently, evidence has shown Pim-1 to be important in prostatic carcinogenesis. In order to further our understanding of its role in prostate cancer...

journal_title：Journal of clinical pathology

authors： Cibull TL,Jones TD,Li L,Eble JN,Ann Baldridge L,Malott SR,Luo Y,Cheng L

更新日期：2006-03-01 00:00:00

abstract：AIMS:The probabilistic approach is widely adopted for breast fine needle aspiration cytology. However, a definite cytological diagnosis is not always possible for C3 (atypia) cases, which poses a management dilemma as this represents a mixed category of benign and malignant cases. It would be beneficial to be able to p...

journal_title：Journal of clinical pathology

authors： Yu SN,Li J,Wong SI,Tsang JYS,Ni YB,Chen J,Tse GM

更新日期：2017-12-01 00:00:00

abstract：:A post-mortem examination, in the case of a 34-year-old man dying suddenly from head injuries sustained in a road accident, showed early cirrhosis of the liver and associated splenomegaly 17 years after an attack of infective hepatitis. The histology of the thymus showed abnormal changes in the medulla, consisting of ...

journal_title：Journal of clinical pathology

authors： CORRIDAN M

更新日期：1963-09-01 00:00:00

abstract：:An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment. ...

journal_title：Journal of clinical pathology

authors： Canning DM,Crane RS,Huntsman RG,Yawson GI

更新日期：1972-04-01 00:00:00

abstract：AIM:To develop a simple but reliable polymerase chain reaction (PCR) method to determine the HIV-1 status of patients on formalin fixed, paraffin wax embedded lymph node tissue. METHODS:Fifty lymph node specimens, 20 from HIV-1 seropositive and 30 from HIV-1 seronegative patients, were analysed. Lymph nodes with a var...

journal_title：Journal of clinical pathology

authors： Slavik T,Wolfaardt M,van Zyl H,Simson IW

更新日期：1995-08-01 00:00:00

abstract：:Mallory bodies were isolated from necropsy livers from patients with alcoholic hepatitis with and without cirrhosis with a Ficoll viscosity barrier. The purity of Mallory bodies in the isolate varied between 70 and 90%, estimated by counting Mallory bodies and non-Mallory body structures in haematoxylin-eosin stained ...

journal_title：Journal of clinical pathology

authors： Gluud C,Hardt F,Aldershvile J,Christoffersen P,Lyon H,Nielsen J

更新日期：1981-09-01 00:00:00

abstract：:Specimens from 95 patients attending a venereal diseases clinic were examined for gonococci by three methods--a conventional culture technique using modified Thayer-Martin medium, microscopy of a Gram-stained direct smear, and the Microcult system. For 56% of the specimens the results by all three methods agreed. Assu...

journal_title：Journal of clinical pathology

authors： Williams RJ,Ratnatunga CS,Hamilton-Miller JM,Brumfitt W

更新日期：1978-03-01 00:00:00

abstract：AIMS:This is a qualitative study of the perceived learning needs of trainees for graded responsibility in histopathological training in the UK. METHODS:A focus group with trainees and interviews with consultants was carried out. Participants were asked 'What do you perceive are the learning needs of histopathology tra...

journal_title：Journal of clinical pathology

authors： Finall A,Allery L

更新日期：2016-01-01 00:00:00

abstract：AIMS:Glypican 3 (GPC3) is a heparan sulphate proteoglycan that shows elevated levels in the serum of patients with hepatocellular carcinoma (HCC), but not in healthy blood donors or patients with benign liver disease. This study explores the value of GPC3 expression for diagnosis of HCC by immunohistochemistry in liver...

journal_title：Journal of clinical pathology

authors： Wang FH,Yip YC,Zhang M,Vong HT,Chan KI,Wai KC,Wen JM

更新日期：2010-07-01 00:00:00

abstract：:The number of granulocyte/macrophage colonies grown in vitro from bone marrow cells obtained from 90 rib segments and 30 ;normal' bone marrow aspirates was found to be highly variable. Considerable variation was also noted in the relationship between colony number and the number of cells cultured in both groups. The a...

journal_title：Journal of clinical pathology

authors： Morris TC,McNeill TA,Bridges JM

更新日期：1974-10-01 00:00:00