Nodal staging of colorectal carcinomas and sentinel nodes.

abstract：:Experiments were performed to evaluate five commercial kit assays used for the detection of antibodies to dsDNA. The kits were compared using a performance index score as recommended by the guidelines of the European Committee for Clinical Laboratory Standards. The highest performance score was obtained using the radi...

journal_title：Journal of clinical pathology

authors： McMillan SA,Fay AC

更新日期：1988-11-01 00:00:00

abstract：:The sensitivity of 12 commonly used anti-HIV-1/HIV-2 enzyme immunoassays was evaluated. The assays, each of which utilises at least one synthetic HIV antigen, were tested against a panel of 1092 specimens previously designated anti-HIV positive. In a total of 13 104 tests there were eight false negative results attrib...

journal_title：Journal of clinical pathology

authors： McAlpine L,Parry JV,Shanson D,Mortimer PP

更新日期：1995-05-01 00:00:00

abstract：:An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at al...

journal_title：Journal of clinical pathology

authors： Tapper-Jones L,Aldred M,Walker DM

更新日期：1980-03-01 00:00:00

abstract：AIMS:Hypomethylating agents (HMAs) exhibit clinical efficacy in patients with myelodysplastic syndromes (MDS) and myelodysplastic/myeloproliferative neoplasms (MDS/MPN). This study was performed to assess residual disease status by flow cytometry immunophenotyping (FCI) methods in patients with MDS or MDS/MPN treated w...

journal_title：Journal of clinical pathology

authors： Huang L,Garcia-Manero G,Jabbour E,Goswami M,Routbort MJ,Medeiros LJ,Jorgensen JL,Wang SA

更新日期：2016-04-15 00:00:00

abstract：AIMS:Venous invasion (VI) is a known independent prognostic indicator of recurrence and survival in colorectal cancer. The guidelines of the Royal College of Pathologists (RCPath) state that, in a series of resections, extramural VI should be detected in at least 25% of specimens. However, there is widespread variabili...

journal_title：Journal of clinical pathology

authors： Messenger DE,Driman DK,McLeod RS,Riddell RH,Kirsch R

更新日期：2011-11-01 00:00:00

abstract：:Assessment of ERBB2 (HER2) status in breast carcinomas has become critical in determining response to the humanised monoclonal antibody trastuzumab. The current joint College of American Pathologists and the American Society of Clinical Oncology guidelines for the evaluation of HER2 status in breast carcinoma involve ...

journal_title：Journal of clinical pathology

authors： Gruver AM,Peerwani Z,Tubbs RR

更新日期：2010-03-01 00:00:00

abstract：:Three patients with aplastic anaemia had a history of substantial previous exposure to organochlorine pesticides. The temporal association between chemical exposure and the onset of first symptoms of anaemia was strongly supportive. Organochlorines have the property of lipid affinity and accumulation in adipose tissue...

journal_title：Journal of clinical pathology

authors： Rugman FP,Cosstick R

更新日期：1990-02-01 00:00:00

abstract：:Gastrointestinal (GI) symptoms including abdominal pain, bloating and diarrhoea are a relatively common reason for consulting a physician. They may be due to inflammatory bowel disease (inflammatory bowel disease; Crohn's disease, ulcerative colitis and indeterminate colitis), malignancy (colorectal cancer), infectiou...

journal_title：Journal of clinical pathology

authors： Sherwood RA

更新日期：2012-11-01 00:00:00

abstract：:The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastrit...

journal_title：Journal of clinical pathology

authors： Stolte M,Eidt S

更新日期：1989-12-01 00:00:00

abstract：AIM:To investigate the fate of Streptococcus pneumoniae C-polysaccharide antigen in serum in patients with S pneumoniae bacteraemia. METHOD:In vitro dissociation experiments were performed to demonstrate that C-polysaccharide was masked by ligands in normal and acute phase serum. Serum samples from 22 patients with S ...

journal_title：Journal of clinical pathology

authors： Gillespie SH,Smith MD,Dickens A,Raynes JG,McAdam KP

更新日期：1995-09-01 00:00:00

abstract：:Methods of speciating Candida isolates from clinical specimens are described and the necessity of speciation is emphasized. Differences in susceptibility of C. albicans and C. tropicalis to amphotericin B were observed and the implications of this in relation to treatment with amphotericin B and the development of res...

journal_title：Journal of clinical pathology

authors： Stieritz DD,Law EJ,Holder IA

更新日期：1973-06-01 00:00:00

abstract：:Two cases are described in which clostridial invasion of the liver and spleen was noted at post-mortem examination. In each there was a history of debilitating disease and it is suggested that the infection was consequent upon impaired immunological and cellular defence mechanisms. ...

journal_title：Journal of clinical pathology

authors： ASHLEY DJ

更新日期：1965-03-01 00:00:00

abstract：:Inherited biochemical defects may present with acute life-threatening illness with a high mortality and morbidity. Some are treatable and have a good outcome with early appropriate intervention. However, because of their rarity, diagnosis is often delayed; they are not considered or investigated appropriately. This is...

journal_title：Journal of clinical pathology

authors： Cook P,Walker V

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Although Hashimoto thyroiditis (HT) is a predisposing factor for B-lineage thyroid lymphoma, clonal B-cell populations in HT are rare. AIM:To investigate whether there is a clonal relationship between HT and primary thyroid lymphoma. METHODS:Clonalilty and sequence similarity was determined by PCR followed...

journal_title：Journal of clinical pathology

authors： Moshynska OV,Saxena A

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:The study sought to determine whether mast cell counts in endobronchial biopsies of large airways are related to mast cell counts in the small airways. METHODS:Lungs, obtained postmortem from 10 subjects who had died of non-respiratory causes, were fixed in inflation. Mast cell densities (cells/mm(3)), de...

journal_title：Journal of clinical pathology

authors： Carroll ML,Carroll NG,Gundersen HJ,James AL

更新日期：2011-05-01 00:00:00

abstract：:Thirteen meningiomas of varying light microscopic features were studied immunohistologically using a panel of monoclonal antibodies directed against epithelial, mesenchymal, and neural components. All 13 meningiomas showed expression of epithelial membrane antigen, vimentin, and S100 protein, as did normal meninges. F...

journal_title：Journal of clinical pathology

authors： Theaker JM,Gatter KC,Esiri MM,Fleming KA

更新日期：1986-04-01 00:00:00

abstract：:The clinical features and special investigations in a case of multiple myelomatosis are described. The finding of exfoliated ;myeloma cells' in the urine of this case is thought to be unique, these cells closely resembling the myeloma cells seen in the bone marrow. The necropsy findings indicated that the origin of th...

journal_title：Journal of clinical pathology

authors： PROWSE CM,BLECHER TE

更新日期：1962-03-01 00:00:00

abstract：AIMS:To determine whether the monoclonal antibody (MoAb) 83D4, previously shown to be highly specific for carcinoma cells, can be used as an immunocytological marker to discriminate between benign and malignant cells in serous effusions; and to test for a correlation between expression of the antigen reacting with MoAb...

journal_title：Journal of clinical pathology

authors： Beuzelin-Yvraut M,Bourguignat A,Phillips E,Roseto A,Osinaga E

更新日期：1995-05-01 00:00:00

abstract：:Increasingly in the field of medicine, new therapeutic modalities, both surgical and non-surgical, are being introduced. Some of these may significantly alter the pathological appearance of normal and neoplastic tissue and result in problems for the pathologist. In this review, iatrogenic pathology within the female g...

journal_title：Journal of clinical pathology

authors： Clarke B,McCluggage WG

更新日期：2009-02-01 00:00:00

abstract：:The aim of this article is to provide knowledge of the origin of catecholamines and metabolites so that there can be an informed approach to the methods for biochemical screening for a possible phaeochromocytoma; The article includes a review of catecholamine and metadrenaline metabolism, with methods used in biochemi...

journal_title：Journal of clinical pathology

authors： Barron J

更新日期：2010-08-01 00:00:00

abstract：:Results of serological investigations on patients with joint pain, arthralgia or polyarthritis were analysed and this information was used to develop a diagnostic algorithm to ensure optimal utilisation of laboratory resources. Accordingly, all cases are now examined for parvovirus IgM, mycoplasma IgM and streptococca...

journal_title：Journal of clinical pathology

authors： Jones JW,Pether JV,Frost RW

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The Wnt pathway is important in cell signalling transduction and is involved in the pathogenesis of multiple tumour types. A comprehensive analysis of the expression of Wnt signalling pathway proteins in mammary phyllodes tumours (PTs) has not been previously performed. AIMS:To evaluate the immunohistochemi...

journal_title：Journal of clinical pathology

authors： Karim RZ,Gerega SK,Yang YH,Horvath L,Spillane A,Carmalt H,Scolyer RA,Lee CS

更新日期：2009-11-01 00:00:00

abstract：AIMS:To investigate how clinical microbiology laboratories should report and interpret mixed mould isolates including Aspergillus species from clinical samples and the criteria for susceptibility testing of the isolates. METHODS:Retrospectively collected data from our laboratory information system of moulds isolated b...

journal_title：Journal of clinical pathology

authors： Purcell J,McKenna J,Critten P,Denning DW,Hassan IA

更新日期：2011-06-01 00:00:00

abstract：AIMS:To compare prognostic information obtained by image analysis cytometry of paraffin wax embedded soft tissue sarcomas with conventional assessment. METHODS:A CAS 200 image analyser was used to determine DNA content of Feulgen stained cytology preparations and tissue sections and to quantify immunostaining by Ki67 ...

journal_title：Journal of clinical pathology

authors： Michie BA,Black C,Reid RP,Barrett A,Hamblen DL

更新日期：1994-05-01 00:00:00

abstract：AIMS:To investigate treatment with glycerol/washing as a potential substitute for freeze-thawing in the production of leucocyte depleted red cell concentrates for patients with a history of non-haemolytic reactions following transfusion. METHODS:The standard procedure of treatment with glycerol/-80 degrees C freezing/...

journal_title：Journal of clinical pathology

authors： Farrugia A,Shea N,Knowles S,Holdsworth R,Piouronowski H,Portbury D,Romeo A

更新日期：1993-08-01 00:00:00

abstract：:A 65-year-old woman with a history of a left heminephrectomy for renal carcinoma developed hypercalcaemia 11 years after the operation. The same kidney was found to contain a recurrent renal carcinoma. After the radical nephrectomy of the left kidney, hypercalcaemia remitted but reappeared 11 months later. The right k...

journal_title：Journal of clinical pathology

authors： Szwed JJ,Gott LJ,Lempke RE,Seo IS

更新日期：1979-03-01 00:00:00

abstract：:Of 22 patients with Kaposi's sarcoma, 16 had the acquired immune deficiency syndrome (AIDS). The histological pattern in AIDS differs from the more familiar classical Kaposi's sarcoma. The features most useful in making the diagnosis are: dissection of collagen; lymphatic vessel like spaces; angiomatoid lesions; premo...

journal_title：Journal of clinical pathology

authors： Francis ND,Parkin JM,Weber J,Boylston AW

更新日期：1986-05-01 00:00:00

abstract：AIMS:To institute recommendations from a laboratory turnround time study; to evaluate audit methods; and to quantify improvements achieved. METHODS:Changes to result report distribution and specimen delivery were affected by posting results directly from the laboratory followed by the introduction of a twice daily cou...

journal_title：Journal of clinical pathology

authors： Smellie WS,Galloway PJ,Johnston JI

更新日期：1995-04-01 00:00:00

abstract：:This report describes the case of a 76 year old man who suffered from febrile ulceronecrotic Mucha-Habermann disease (FUMHD). Despite this patient's typical clinical and histological findings, the fulminating course led to death. Polymerase chain reaction (PCR) analysis of the skin lesions showed that the infiltrating...

journal_title：Journal of clinical pathology

authors： Miyamoto T,Takayama N,Kitada S,Hagari Y,Mihara M

更新日期：2003-10-01 00:00:00

abstract：:A rapid technique using a non-radioactive receptor molecule (digoxigenin) for intrahepatic hepatitis B virus (HBV) DNA detection using in situ hybridisation was developed. It can be adapted for use in combination with standard immunohistochemistry for simultaneous detection of both HBV DNA and HBV antigens. The total ...

journal_title：Journal of clinical pathology

authors： Lau JY,Naoumov NV,Alexander GJ,Williams R

更新日期：1991-11-01 00:00:00