p53, c-myc p62 and proliferating cell nuclear antigen (PCNA) expression in non-Hodgkin's lymphomas.

abstract：:Dilated cardiomyopathy (DCM) represents a common genetic cause of mechanical and/or electrical dysfunction leading to heart failure (HF) onset for which truncating variants in titin (TTN) gene result in the most frequent mutations. Moreover, myocyte and endothelial cell apoptosis is a key endophenotype underlying card...

journal_title：Journal of clinical pathology

authors： Mansueto G,Benincasa G,Della Mura N,Nicoletti GF,Napoli C

更新日期：2020-09-01 00:00:00

abstract：:The cytological features of testicular germ cell tumours were established in smears from 15 freshly resected tumours. These features were applied to the fine needle aspiration cytology diagnosis of metastases in 27 patients referred for chemotherapy. There were 16 positive reports in 32 aspirates of which 13 were take...

journal_title：Journal of clinical pathology

authors： Highman WJ,Oliver RT

更新日期：1987-11-01 00:00:00

abstract：:Care in the preparation and preservation of reagents, together with certain modifications in apparatus and technique, have eliminated the difficulties from plasma ammonia analysis. Ammonia contamination from the laboratory atmosphere has not proved an especial hazard, and no major setback has been encountered in the a...

journal_title：Journal of clinical pathology

authors： Fenton JC,Williams AH

更新日期：1968-01-01 00:00:00

abstract：:Sera can produce nuclear or perinuclear immunofluorescence staining in neutrophils which may be caused by antibodies with differing antigenic specificities. These include perinuclear antineutrophil cytoplasmic antibodies (P-ANCA), granulocyte specific antinuclear antibody (GS-ANA), and antinuclear antibody (ANA). Ther...

journal_title：Journal of clinical pathology

authors： Chowdhury SM,Broomhead V,Spickett GP,Wilkinson R

更新日期：1999-06-01 00:00:00

abstract：:In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal p...

journal_title：Journal of clinical pathology

authors： Thielemans C,Aelbrecht W,Verbeelen D,Somers G,De Waele M,Van Camp B

更新日期：1982-03-01 00:00:00

abstract：:Laboratory studies on clotrimazole showed that it had marked activity in vitro against all the Candida spp. and Cryptococcus spp. tested, against almost all strains of dermatophytes, and against Aspergillus spp and other fungal genera responsible for systemic mycoses; it had limited activity towards Gram-positive bact...

journal_title：Journal of clinical pathology

authors： Holt RJ,Newman RL

更新日期：1972-12-01 00:00:00

abstract：:Plasma fibronectin concentrations up to 85 mg/100 ml were found in hyperthyroid patients. There was a significant correlation between free thyroxine index and plasma fibronectin values. Hypothyroid patients had low to normal fibronectin concentrations. Parallel decreases of thyroid hormones and plasma fibronectin conc...

journal_title：Journal of clinical pathology

authors： Graninger W,Pirich K,Derfler K,Waldhäusl W

更新日期：1985-01-01 00:00:00

abstract：:Chronic myelomonocytic leukaemia (CMML) is a myelodysplastic syndrome with a diverse clinical spectrum. A case of a 60 year old man with CMML who developed cardiac tamponade is reported. Cytological examination of the pericardial effusion fluid showed extramedullary haemopoiesis. Serous effusions are well recognised i...

journal_title：Journal of clinical pathology

authors： Bradford CR,Smith SR,Wallis JP

更新日期：1993-07-01 00:00:00

abstract：:This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass. ...

journal_title：Journal of clinical pathology

authors： Horwood E,Dowson H,Gupta R,Kaczmarski R,Williamson M

更新日期：2003-02-01 00:00:00

abstract：:Eosinophil polymorphonuclear leucocytes (polymorphs) were counted in 45 specimens from patients with Hodgkin's disease and five specimens from patients with reactive follicular hyperplasia. The use of chlorazol fast pink BK, a little known stain for eosinophil polymorphs, combined with image analysis facilitated rapid...

journal_title：Journal of clinical pathology

authors： Fuggle WJ,Crocker J,Smith PJ

更新日期：1984-03-01 00:00:00

abstract：:It was postulated that the short chain fatty acids (SCFA) produced by anaerobic bacteria might serve as microbial markers in purulent material. Eighteen pus specimens from various sources were analysed by gas-liquid chromatography (GLC), and the SCFA detected were compared with the microorganisms isolated by conventio...

journal_title：Journal of clinical pathology

authors： Ladas S,Arapakis G,Malamou-Ladas H,Palikaris G,Arseni A

更新日期：1979-11-01 00:00:00

abstract：AIMS:To assess the relevance of genetic variants of hepatitis B virus (HBV) and to demonstrate the usefulness of the polymerase chain reaction (PCR) in cases of HBV diagnostic difficulty. METHODS:Five serum samples from patients that presented diagnostic difficulty in routine laboratories were sent to a research labor...

journal_title：Journal of clinical pathology

authors： van Deursen FJ,Hino K,Wyatt D,Molyneaux P,Yates P,Wallace LA,Dow BC,Carman WF

更新日期：1998-02-01 00:00:00

abstract：:The production of heparinase by a wide range of anaerobic bacteria isolated from clinical specimens was investigated. None of the 29 strains of Bacteroides fragilis produced heparinase. Of 62 other Bacteroides tested, only two of four strains of B ovatus, two of three strains of B thetaiotaomicron, and two of four str...

journal_title：Journal of clinical pathology

authors： Riley TV

更新日期：1987-04-01 00:00:00

abstract：:During 1971 and 1972, 71 cultures of neisseriae that attacked lactose were received by this laboratory. All strains except one from an eye swab were from the nasopharynx of healthy subjects. Nineteen similar strains from the nasopharynx were isolated in this laboratory. The characteristics of these strains were compar...

journal_title：Journal of clinical pathology

authors： Pykett AH

更新日期：1973-06-01 00:00:00

abstract：:A simple, standardised procedure was used for processing data from External Quality Assessment Schemes and for producing performance charts. A graphic presentation of cumulative performance is generated for each test, using an integrated software package to display results in a standardised format. This permits interp...

journal_title：Journal of clinical pathology

authors： Ardern JC,Hyde K,Hickman L,Urmston A,Burgess R,Burn AM,Geary CG

更新日期：1991-01-01 00:00:00

abstract：:Pathological findings are described in four cases of a new aminoaciduria in which homocystine is excreted in the urine. All the patients were mentally retarded children. Three of them presented diagnostic features of Marfan's syndrome. Necropsy on one case and biopsy findings in the others are described. Fatty change ...

journal_title：Journal of clinical pathology

authors： GIBSON JB,CARSON NA,NEILL DW

更新日期：1964-07-01 00:00:00

abstract：AIM:To compare the sensitivity and staining pattern of the new immunohistochemical antibody to tyrosinase (T311) with S-100, HMB45, and the recently evaluated antibody to melan-A (A103) in a range of melanocytic lesions. METHOD:Archival, formalin fixed, paraffin wax embedded sections from 50 benign and malignant melan...

journal_title：Journal of clinical pathology

authors： Clarkson KS,Sturdgess IC,Molyneux AJ

更新日期：2001-03-01 00:00:00

abstract：:Fourteen formalin fixed and paraffin wax embedded biopsy specimens from 10 women (age range 34-68) presenting with pseudomembranous trigonitis were studied using a combination of anti-oestrogen receptor monoclonal antibodies in an avidin-biotin immunoperoxidase technique. All epithelial areas showing vaginal metaplasi...

journal_title：Journal of clinical pathology

authors： Stephenson TJ,Henry L,Harris SC,Giri DD,Fox M,Underwood JC

更新日期：1989-09-01 00:00:00

abstract：:This paper records the results of the intravenous inoculation of chick embryos with type 5 gonococci and establishes that these strains are pathogenic. ...

journal_title：Journal of clinical pathology

authors： Hafiz S,Jennings R,McEntegart MG,Jephcott AE

更新日期：1978-05-01 00:00:00

abstract：:Lymphocyte-depleted classical Hodgkin lymphoma (LDCHL) is the rarest entity among the classical Hodgkin lymphoma (CHL) subtypes, accounting for <1% of CHL cases in Western countries. Similarly, primary splenic Hodgkin lymphoma is a rare diagnosis among all cases of lymphomatous involvement of spleen. Representing a co...

journal_title：Journal of clinical pathology

authors： Parekh V,Peker D

更新日期：2015-11-01 00:00:00

abstract：:The activities of phosphohexose isomerase and 6-phosphogluconate dehydrogenase have been studied in the vaginal fluid of women from the gynaecological departments. Women from these departments gave a very high false positive rate, though no cases of carcinoma in situ were not detected by estimating phosphohexose isome...

journal_title：Journal of clinical pathology

authors： Muir GG

更新日期：1966-07-01 00:00:00

abstract：:The association between asymptomatic primary sclerosing cholangitis and exocrine pancreatic disease was underlined by the findings in a patient with cystic fibrosis and in another with chronic pancreatitis. In each case hepatocytes showed extensive microvesicular steatosis and studies of drug metabolism suggested hepa...

journal_title：Journal of clinical pathology

authors： Benett I,Salh B,Haboubi NY,Braganza JM

更新日期：1989-05-01 00:00:00

abstract：:Partial myoepithelial differentiation is common in simple epithelial hyperplasia (epitheliosis) of the breast but functional myoepithelial differentiation with basement membrane production is exceedingly rare. A peculiar change of hyaline globules within benign epithelial hyperplasia has been recognised before as "col...

journal_title：Journal of clinical pathology

authors： Wells CA,Wells CW,Yeomans P,Viña M,Jordan S,d'Ardenne AJ

更新日期：1990-11-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the mismatch repair gene expression and their correlation with NF-kB in patients with oral squamous cell carcinoma (SCC). METHODS:Total RNA was isolated from 28 biopsy samples. A control group was composed of 20 volunteers. Differential expression of hMSH2, hMSH6 and NF-kB ge...

journal_title：Journal of clinical pathology

authors： Fonseca A,Perez M,Veiga G,Prosdócimi F,Nunes F,Bianco B,Fonseca F,Alves B

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Squamous differentiation/squamous metaplasia is often associated with endometrial adenocarcinoma and benign lesions, such as endometrial hyperplasia and chronic endometritis. Morules have distinct histological characteristics, and are referred to as squamous metaplasia or squamoid metaplasia. AIM:To focus o...

journal_title：Journal of clinical pathology

authors： Chinen K,Kamiyama K,Kinjo T,Arasaki A,Ihama Y,Hamada T,Iwamasa T

更新日期：2004-09-01 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：:An automated method for the microbiological assay of vitamin B(12) is described. A chloramphenicol-resistant strain of Lactobacillus leichmannii is used as the test organism and this eliminates the need for sterilization or aseptic addition. Precipitation of the serum protein is avoided by dilution of the serum with a...

journal_title：Journal of clinical pathology

authors： Davis RE,Moulton J,Kelly A

更新日期：1973-07-01 00:00:00

abstract：:Nearly two thousand clinical samples were examined by direct gas-liquid chromatography over a three year period. Absence of volatile fatty acids (VFAs) in the samples correlated well with negative culture results for anaerobic bacteria. In general the presence of acetic acid alone correlated well with the presence of ...

journal_title：Journal of clinical pathology

authors： Watt B,Geddes PA,Greenan OA,Napier SK,Mitchell A

更新日期：1982-07-01 00:00:00

abstract：AIM:To develop a unified diagnostic approach for the detection of human papillomavirus (HPV) DNA in skin and mucosal biopsies from both immunocompetent and immunosuppressed individuals using a degenerate polymerase chain reaction (PCR) method. METHODS:The sensitivity and specificity of three published degenerate prime...

journal_title：Journal of clinical pathology

authors： Surentheran T,Harwood CA,Spink PJ,Sinclair AL,Leigh IM,Proby CM,McGregor JM,Breuer J

更新日期：1998-08-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00