Inhibition of fibrin monomer polymerisation by myeloma immunoglobulin.

abstract：:During the last decade, a dramatic rise in the development and application of artificial intelligence (AI) tools for use in pathology services has occurred. This trend is often expected to continue and reshape the field of pathology in the coming years. The deployment of computational pathology and applications of AI ...

journal_title：Journal of clinical pathology

authors： Rakha EA,Toss M,Shiino S,Gamble P,Jaroensri R,Mermel CH,Chen PC

更新日期：2020-08-06 00:00:00

abstract：:A simple, standardised procedure was used for processing data from External Quality Assessment Schemes and for producing performance charts. A graphic presentation of cumulative performance is generated for each test, using an integrated software package to display results in a standardised format. This permits interp...

journal_title：Journal of clinical pathology

authors： Ardern JC,Hyde K,Hickman L,Urmston A,Burgess R,Burn AM,Geary CG

更新日期：1991-01-01 00:00:00

abstract：:The pathological findings of an intradural and extramedullary cyst in the mid cervical spinal canal are described in a 55 year old woman who presented with a short history of pain and paraesthesia of the right arm. Intradural well defined solitary cystic lesions in the spinal canal are uncommon, their pathogenesis is ...

journal_title：Journal of clinical pathology

authors： Wilkinson N,Reid H,Hughes D

更新日期：1992-11-01 00:00:00

abstract：:This report describes a case of refractory enteropathy with circulating intestinal goblet cell autoantibodies (IGA). A 19 year old man with hyperthyroidism had suffered from protracted diarrhoea for nearly 10 years. Histological examination showed evidence of collagenous enterocolitis. The diarrhoea did not improve de...

journal_title：Journal of clinical pathology

authors： Hori K,Fukuda Y,Tomita T,Kosaka T,Tamura K,Nishigami T,Kubota A,Shimoyama T

更新日期：2003-08-01 00:00:00

abstract：:Targeted next-generation sequencing using the 50-gene Ion AmpliSeq Cancer Hotspot Panel v2 identified two significant point mutations in endometrial stromal sarcomas (ESS). Case 1 is a uterine mass from a quadragenarian woman with a karyotype lacking any known ESS rearrangements but demonstrated to have a CTNNB1-activ...

journal_title：Journal of clinical pathology

authors： Patel SB,McCormack C,Hodge JC

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Optimal management of patients with lung cancer requires accurate cell typing of tumours and staging at the time of diagnosis. Endobronchial ultrasound-guided lymph node aspiration as a method of diagnosing and staging lung cancer is a relatively new technique. AIM:To report the use of liquid-based-thin-lay...

journal_title：Journal of clinical pathology

authors： Wallace WA,Monaghan HM,Salter DM,Gibbons MA,Skwarski KM

更新日期：2007-04-01 00:00:00

abstract：:The T(4)-free thyroxine index was used as the thyroid function test of first choice in a district general hospital for one year. Ninety-two patients were assessed both initially and at follow up by a single physician. The index agreed with clinical assessment in 69 out of 74 patients in whom diagnosis was unequivocal....

journal_title：Journal of clinical pathology

authors： Howorth PJ,Ward RL

更新日期：1972-03-01 00:00:00

abstract：:Although Neisseria species other than N gonorrhoeae and N meningitidis normally comprise part of the commensal bacterial flora of the oropharynx, they may occasionally act as opportunistic pathogens. Infections in which these organisms have been implicated include cases of endocarditis, meningitis, septicaemia, otitis...

journal_title：Journal of clinical pathology

authors： Johnson AP

更新日期：1983-02-01 00:00:00

abstract：:Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal ep...

journal_title：Journal of clinical pathology

authors： Jenkins D,Stephenson PM,Scott BB

更新日期：1985-03-01 00:00:00

abstract：:Visceral botryomycosis is rare, and documented sites are lung, brain, kidney, liver and prostate. This report describes a rare autopsy case of disseminated visceral botryomycosis, with bulky, grape-like botryomycotic vegetations in the heart, and similar abscesses in the lungs and bone marrow. This is the first such r...

journal_title：Journal of clinical pathology

authors： Gupta K,Das A,Radotra BD,Bhalla A

更新日期：2008-08-01 00:00:00

abstract：:Plasma antithrombin levels were measured by clotting, immunological, and amidolytic methods on two groups of subjects: 20 normal individuals and nine patients studied serially post-operatively (hip replacement). The postoperative patients were observed for the emergence of deep-vein thrombosis using 125I-fibrinogen up...

journal_title：Journal of clinical pathology

authors： McLellan DS,Devlin JD,Heyse-Moore GH,Aronstam A

更新日期：1980-05-01 00:00:00

abstract：AIMS:To ascertain the effect of enhanced surveillance following an outbreak of waterborne cryptosporidiosis on the number of faecal specimens submitted to the local microbiology laboratory and the number positive for common enteric pathogens. The outbreak provided an opportunity to estimate the extent of routine under ...

journal_title：Journal of clinical pathology

authors： Qamruddin AO,Keaney MG,McCann R,Chadwick PR

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Although Bulgaria has one of the highest rates of cervical cancer incidence and mortality in the EU, data on HPV type distribution are limited. AIM:To determine the prevalence of HPV types 16 and 18 in archival specimens from cervical cancer cases from Bulgaria. METHODS:A total of 145 formalin-fixed, paraf...

journal_title：Journal of clinical pathology

authors： Todorova I,Ganchev G,Shikova E

更新日期：2010-12-01 00:00:00

abstract：AIMS:Meticillin-resistant Staphylococcus aureus (MRSA) strains isolated in Tawam Hospital, a tertiary care hospital in the United Arab Emirates, were examined in order to understand the reasons for a doubling of its incidence between 2003 and 2008 while maintaining the same infection control measures. METHODS:All cons...

journal_title：Journal of clinical pathology

authors： Sonnevend Á,Blair I,Alkaabi M,Jumaa P,Al Haj M,Ghazawi A,Akawi N,Jouhar FS,Hamadeh MB,Pál T

更新日期：2012-02-01 00:00:00

abstract：AIMS:To determine the value of squamous mucosal histology in the assessment of patients with gastro-oesophageal reflux symptoms. METHODS:Sixty six patients with reflux symptoms underwent endoscopy with oesophageal biopsy, manometry, and 24 hour oesophageal pH testing. The following histological features were assessed ...

journal_title：Journal of clinical pathology

authors： Bowrey DJ,Williams GT,Clark GW

更新日期：2003-03-01 00:00:00

abstract：:The technique devised by Moore (1960) for determining the sensitivity of staphylococci to mercuric chloride was investigated and the effect of variations in the medium determined. An alternative technique, in which paper discs impregnated with phenyl mercuric nitrate are used, was found to give identical results. Thre...

journal_title：Journal of clinical pathology

authors： GREEN SM

更新日期：1962-05-01 00:00:00

abstract：AIMS:To establish a mechanism to examine the components of turnaround time in a representative cross-section of laboratory users; and to identify potential areas for improvement. METHODS:Information was collected manually from result reports received by eight laboratory users: three wards in the main hospital, four GP...

journal_title：Journal of clinical pathology

authors： Smellie WS,Johnston J,Galloway PJ

更新日期：1994-07-01 00:00:00

abstract：:As patients with multiple myeloma (MM) have a variable clinical course, predictive markers would help determine the appropriate treatment strategy. Clinical staging is commonly used to predict outcome, but tumour marker expression and the underlying genetic changes are increasingly used to assess the biological aggres...

journal_title：Journal of clinical pathology

authors： Yeung J,Chang H

更新日期：2008-07-01 00:00:00

abstract：AIMS:To determine whether the recommended methods for the handling of breast excision biopsy specimens from screening patients cause more laboratory work than those used for non-screening patients. METHODS:All breast excision biopsy specimens from 1990 were identified. Ninety one came from patients identified during t...

journal_title：Journal of clinical pathology

authors： Green B,McDicken IW,Turnbull LS

更新日期：1992-06-01 00:00:00

abstract：:An ultramicro electrophoretic technique for the separation of serum lipoproteins is described using agarose gel on microscope slides.The interaction between the agarose gel and lipoproteins has been reduced and the separation between beta- and pre-beta-lipoproteins has been improved over existing methods. A semiquanti...

journal_title：Journal of clinical pathology

authors： Elphick MC

更新日期：1971-02-01 00:00:00

abstract：:Accurate histopathological assessment of biopsies is important for the diagnosis, subclassification, and management of chronic idiopathic inflammatory bowel disease (IBD). British Society of Gastroenterology (BSG) guidelines for the initial histopathological diagnosis of IBD were published in 1997. Changes since then ...

journal_title：Journal of clinical pathology

authors： Feakins RM,British Society of Gastroenterology.

更新日期：2013-12-01 00:00:00

abstract：AIM:To determine the frequency, pattern and distribution of stromal keratin expression in phyllodes tumours if any, which may impact diagnostic approaches. METHODS:The clinicopathological features of 109 phyllodes tumours comprising 70 (64.2%) benign, 30 (27.5%) borderline and nine (8.3%) malignant grades were evaluat...

journal_title：Journal of clinical pathology

authors： Chia Y,Thike AA,Cheok PY,Yong-Zheng Chong L,Man-Kit Tse G,Tan PH

更新日期：2012-04-01 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the risk factors for proximal resection margin involvement and its impact on survival outcome in patients with proximal gastric cancer. METHODS:A total of 488 patients who underwent potentially curative resection for proximal gastric cancer were retrospectively reviewed. Clini...

journal_title：Journal of clinical pathology

authors： Zhao B,Lu H,Bao S,Luo R,Mei D,Xu H,Huang B

更新日期：2020-08-01 00:00:00

abstract：:The histological appearances of the breast in a patient with mucoviscidosis are those of complete lobular agenesis. Ducts and ductules are well developed, and there is abundant fibrous tissue giving the breast a normal contour. The appearances are contrasted with those of gynaecomastia, and the aetiology is discussed....

journal_title：Journal of clinical pathology

authors： Ward AM

更新日期：1972-02-01 00:00:00

abstract：:Six fetal and 10 neonatal rat or mouse stomachs and a 14-week human fetal stomach were examined for immunofluorescence reactivity with four sera containing parietal cell antibody (PCA) and four other sera containing smooth muscle antibody (SMA). In rat and mouse stomachs, parietal cells first reacted with PCA in 19-da...

journal_title：Journal of clinical pathology

authors： Ceredig R,Toh BH

更新日期：1978-06-01 00:00:00

abstract：:In the course of the Paris study on risk factors of cardiovascular disease in a large professional group, 7710 active and apparently healthy men aged between 48 and 54 were examined. This study measured the relationship between clinical abnormalities suggesting alcoholic liver disease (ALD) and the following blood par...

journal_title：Journal of clinical pathology

authors： Eschwege E,Papoz L,Lellouch J,Claude JR,Cubeau J,Pequignot G,Richard JL,Schwartz D

更新日期：1978-07-01 00:00:00

abstract：AIMS:Soft tissue tumours are a heterogeneous group of neoplasms that can arise at almost every anatomical site. As they often show similar clinical and radiological findings, histology is the definitive diagnostic method and it is crucial that the surgical pathology report contains accurate, useful information for mana...

journal_title：Journal of clinical pathology

authors： Shah C,Wang J,Mubako T,Fisher C,Thway K

更新日期：2016-09-01 00:00:00

abstract：:The apparent volumes of distribution of Evans blue and (59)Fe-dextran were determined in 18 studies.(59)Fe-dextran volume was 5% lower than Evans blue volume, a highly significant difference. The rate of loss of (59)Fe dextran from the circulation was significantly less than that of Evans blue. ...

journal_title：Journal of clinical pathology

authors： Wilson RJ,Mills IH

更新日期：1970-05-01 00:00:00

abstract：AIMS:To investigate the expression of catenins (alpha, beta, and gamma) in non-small cell lung carcinoma (NSCLC) and its relation to clinicopathological factors and prognosis. METHODS:The expression of catenins was analysed immunohistochemically in 261 patients with resected NSCLC, diagnosed between 1978 and 1996 in e...

journal_title：Journal of clinical pathology

authors： Pirinen RT,Hirvikoski P,Johansson RT,Hollmén S,Kosma VM

更新日期：2001-05-01 00:00:00