Human papillomavirus prevalence in invasive cervical carcinomas in Bulgaria.

abstract：AIM:To investigate serum placental-type alkaline phosphatase (PLAP-type) activities in women with squamous and glandular malignancies of the reproductive tract using an immunoradiometric assay. METHODS:PLAP-type immunoreactivity was measured in 180 women with non-ovarian malignancies of the reproductive tract and the ...

journal_title：Journal of clinical pathology

authors： Ind TE,Iles RK,Carter PG,Lowe DG,Shepherd JH,Hudson CN,Chard T

更新日期：1994-11-01 00:00:00

abstract：:This review focuses on the pathological features of dysplasia in Barrett's oesophagus. Two categorisation schemes are used for grading dysplasia in the gastrointestinal tract, including Barrett's oesophagus. The inflammatory bowel disease dysplasia morphology study group system is the one most commonly used in the USA...

journal_title：Journal of clinical pathology

authors： Odze RD

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Periostin is a secreted adhesion protein, normally expressed in mesenchime-derived cells. Aberrant expression of the periostin gene in epithelial tumours seems to play a role in angiogenesis and metastases. AIMS:To investigate periostin expression in a consecutive series of breast carcinomas and correlate i...

journal_title：Journal of clinical pathology

authors： Puglisi F,Puppin C,Pegolo E,Andreetta C,Pascoletti G,D'Aurizio F,Pandolfi M,Fasola G,Piga A,Damante G,Di Loreto C

更新日期：2008-04-01 00:00:00

abstract：AIMS:Optical microscopic (OM) evaluation of peripheral blood (PB) cells is still a crucial step of the laboratory haematological workflow. The morphological cell analysis is time-consuming and expensive and it requires skilled operator. To address these challenges, automated image-processing systems, as digital morphol...

journal_title：Journal of clinical pathology

authors： Da Rin G,Benegiamo A,Di Fabio AM,Dima F,Francione S,Fanelli A,Germagnoli L,Lorubbio M,Marzoni A,Pajola R,Pipitone S,Rolla R,Seghezzi M,Baigorria Vaca MDC,Bartolini A,Buoro S

更新日期：2020-09-14 00:00:00

abstract：:A simple laboratory method for culture of continuous ambulatory peritoneal dialysis (CAPD) fluids is described. Guidelines for antimicrobial therapy are discussed based on results from 18 patients studied over an 11-week period. Cephalosporins appeared to be a rational choice for therapy while awaiting laboratory resu...

journal_title：Journal of clinical pathology

authors： Fenton P

更新日期：1982-11-01 00:00:00

abstract：AIM:The immunoproteasome is a specific proteasome isoform whose proteolytic activity enhances the generation of antigenic peptides to be presented by major histocompatibility complex class I molecules to CD8+ T cells. Physiologically, it is expressed abundantly in immune cells and is induced in somatic cells by cytokin...

journal_title：Journal of clinical pathology

authors： Kiuchi T,Tomaru U,Ishizu A,Imagawa M,Iwasaki S,Suzuki A,Otsuka N,Ohhara Y,Kinoshita I,Matsuno Y,Dosaka-Akita H,Kasahara M

更新日期：2020-09-17 00:00:00

abstract：:A 60 year old woman affected by Hashimoto's thyroiditis presented with a history of recurring episodes of urticaria and angio-oedema. Clinical and laboratory evaluation of the patient excluded allergy to external agents, hereditary angio-oedema, and occult infections. A pathogenic relation between Hashimoto's thyroidi...

journal_title：Journal of clinical pathology

authors： Amoroso A,Garzia P,Pasquarelli C,Sportelli G,Afeltra A

更新日期：1997-03-01 00:00:00

abstract：:Liver function was assessed in 38 Edinburgh haemophiliacs. Results before the introduction of NHS intermediate factor VIII concentrate from 1974 onwards were compared with values in 1979. Measurements of serum bile salts in 16 patients as well as conventional liver function tests gave useful evidence of deranged liver...

journal_title：Journal of clinical pathology

authors： Stirling ML,Beckett GJ,Percy-Robb IW

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To compare the whole genomes sequencing (WGS) results in the 100K Genomes project with the results of routine molecular diagnostics in precision medicine. MATERIALS AND METHODS:We analysed 374 cancers including a high tumour mutational burden (TMB-high) subgroup, defined as >10 non-synonymous single nucleoti...

journal_title：Journal of clinical pathology

authors： Echejoh G,Liu Y,Chung-Faye G,Charlton J,Moorhead J,Clark B,Davidson P,Sarker D,Ross P,Ooft ML

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Fibrinogen plays a crucial role in the pathophysiology of tumour cell growth, invasion and metastasis. The aim of this study was to evaluate the prognostic significance of pretreatment plasma fibrinogen levels in patients with diffuse large B cell lymphoma (DLBCL) METHODS: Data from 372 patients with DLBCL, ...

journal_title：Journal of clinical pathology

authors： Troppan KT,Melchardt T,Wenzl K,Schlick K,Deutsch A,Bullock MD,Reitz D,Beham-Schmid C,Weiss L,Neureiter D,Tränkenschuh W,Greil R,Neumeister P,Egle A,Pichler M

更新日期：2016-04-01 00:00:00

abstract：:The incidence of placenta accreta, defined as the abnormal adherence of the placenta to the uterine wall, has been increasing alarmingly in the developed as well as the developing world. There is considerable maternal morbidity and mortality related to the condition. The pathophysiology focuses on the balance between ...

journal_title：Journal of clinical pathology

authors： Khong TY

更新日期：2008-12-01 00:00:00

abstract：:In a study of a group of 325 blood donors between the ages of 18 and 65 years, the total leucocyte and polymorph counts of the females aged 50 to 65 years were found to be significantly lower than those of the corresponding group of male donors. In the whole series of female donors, there were significantly lower tota...

journal_title：Journal of clinical pathology

authors： Allan RN,Alexander MK

更新日期：1968-11-01 00:00:00

abstract：AIMS:N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been shown to be useful for ruling out heart failure in primary care. In this study, we examined the accuracy of the Cobas h232 point-of-care (POC) instrument in primary care compared with an in-hospital measurement. Furthermore, we investigated the user-fr...

journal_title：Journal of clinical pathology

authors： Hex C,Smeets M,Penders J,Van Hoof V,Verbakel J,Buntinx F,Vaes B

更新日期：2018-06-01 00:00:00

abstract：AIMS:To ascertain the effect of enhanced surveillance following an outbreak of waterborne cryptosporidiosis on the number of faecal specimens submitted to the local microbiology laboratory and the number positive for common enteric pathogens. The outbreak provided an opportunity to estimate the extent of routine under ...

journal_title：Journal of clinical pathology

authors： Qamruddin AO,Keaney MG,McCann R,Chadwick PR

更新日期：2002-04-01 00:00:00

abstract：:Sera from 5171 inpatients have been tested for HBAg and HBAb during the 18-month period ending in December 1972. The incidence of HBAg (0.116%) was similar to that in blood donors (0.119%) in the same area, being tested for the first time by the same technique. By contrast the incidence of HBAb in patients (0.271%) wa...

journal_title：Journal of clinical pathology

authors： Payne RW,Barr A,Wallace J

更新日期：1974-02-01 00:00:00

abstract：:The diagnostic value of the Becton Dickinson Radioassay Kit (125I) for the the assay of red cell folate has been investigated. The assay was acceptable with regards to precision but was non-linear with changing packed cell volume. Sensitivity of the assay was satisfactory, with 24 of 25 folate deficient patients givin...

journal_title：Journal of clinical pathology

authors： Bain BJ,Wickramasinghe SN,Broom GN,Litwinczuk RA,Sims J

更新日期：1984-08-01 00:00:00

abstract：:Current techniques for lymphocyte transformation are evaluated and criticised. A simple technique, designed to meet these criticisms, is described in detail, with particular reference to lymphocyte separation and scoring methods. ...

journal_title：Journal of clinical pathology

authors： Pentycross CR

更新日期：1968-03-01 00:00:00

abstract：OBJECTIVE:We explore factors such as the blood sampling site (capillary vs venous), the equipment (HemoCue vs automated haematology analyser) and the model of the HemoCue device (201+ vs 301) that may impact haemoglobin measurements in capillary and venous blood. METHODS:Eleven studies were identified, and bias, conco...

journal_title：Journal of clinical pathology

authors： Rappaport AI,Karakochuk CD,Hess SY,Whitehead RD Jr,Namaste SML,Dary O,Parker ME,Neufeld LM,Larson LM,Newton S,Wegmuller R,Moorthy D

更新日期：2020-10-06 00:00:00

abstract：AIMS:To investigate the relation between sarcoidosis and lymphoma. METHODS:The hospital notes of five patients with sarcoidosis and a lymphoproliferative disorder were reviewed. Histological material on which the diagnoses of sarcoidosis and lymphoma were made was re-analysed. RESULTS:Four of the five patients had we...

journal_title：Journal of clinical pathology

authors： Karakantza M,Matutes E,MacLennan K,O'Connor NT,Srivastava PC,Catovsky D

更新日期：1996-03-01 00:00:00

abstract：AIMS:Pim-1 is a serine/threonine kinase that has been shown to play an integral role in the development of a number of human cancers, such as haematolymphoid malignancies. Recently, evidence has shown Pim-1 to be important in prostatic carcinogenesis. In order to further our understanding of its role in prostate cancer...

journal_title：Journal of clinical pathology

authors： Cibull TL,Jones TD,Li L,Eble JN,Ann Baldridge L,Malott SR,Luo Y,Cheng L

更新日期：2006-03-01 00:00:00

abstract：:A quantitative method of estimating heparin co-factor in terms of percentage activity is presented. The activity in sera from 75 normal subjects varied little from 100%. Low results were obtained in sera from 50 cases of varying types of malignancy. ...

journal_title：Journal of clinical pathology

authors： TEMPERLEY IJ

更新日期：1963-03-01 00:00:00

abstract：AIMS:To determine whether the recommended methods for the handling of breast excision biopsy specimens from screening patients cause more laboratory work than those used for non-screening patients. METHODS:All breast excision biopsy specimens from 1990 were identified. Ninety one came from patients identified during t...

journal_title：Journal of clinical pathology

authors： Green B,McDicken IW,Turnbull LS

更新日期：1992-06-01 00:00:00

abstract：AIM:To establish the diagnostic value of in situ hybridisation and the nested polymerase chain reaction (PCR) in detecting clinically relevant cytomegalovirus (CMV) infection in upper gastrointestinal biopsies from heart transplant patients. METHODS:Test sensitivity and specificity for detection of CMV early gene RNA ...

journal_title：Journal of clinical pathology

authors： Muir SW,Murray J,Farquharson MA,Wheatley DJ,McPhaden AR

更新日期：1998-11-01 00:00:00

abstract：AIM:The evaluation of allelic losses at the FHIT and the BRCA1 genes and at three other loci at the 17q region in a series of 34 sporadic breast cancer cases from Southern Brazil. METHODS:The samples were evaluated for loss of heterozygosity (LOH) at the FHIT and the BRCA1 genes and at three other microsatellite marke...

journal_title：Journal of clinical pathology

authors： Santos SC,Cavalli LR,Cavalli IJ,Lima RS,Haddad BR,Ribeiro EM

更新日期：2004-04-01 00:00:00

abstract：:This review deals with difficulties of diagnosis in cutaneous malignant melanoma encountered by histopathologists of variable seniority and is based on referred material at The Royal Marsden Hospital over a 20-year period and on the experience of more than two-and-a-half thousand cases referred to The World Health Org...

journal_title：Journal of clinical pathology

authors： Levene A

更新日期：1980-02-01 00:00:00

abstract：:In an era when immunohistochemistry (IHC) is increasingly depended on for histological subtyping, and IHC-determined biomarker informing rapid treatment choices is on the horizon; reproducible, quantifiable techniques are required. This study aimed to compare automated IHC scoring to quantify 6 DNA damage response pro...

journal_title：Journal of clinical pathology

authors： Gentles L,Howarth R,Lee WJ,Sharma-Saha S,Ralte A,Curtin N,Drew Y,O'Donnell RL

更新日期：2020-11-19 00:00:00

abstract：:Routine anaerobic culture of urine identified the urinary tract as the primary focus of sepsis in a postoperative patient with Bacteroides fragilis septicaemia. Specimens of urine from six other symptomatic patients grew > 10(8) cfu/litre of a Bacteroides species in pure growth. The significance of these isolates is d...

journal_title：Journal of clinical pathology

authors： Bannon J,Hatem MH,Noone M

更新日期：1998-09-01 00:00:00

abstract：:The test is an application of the method originally described by Boyden (1951) and adapted by Stavitsky and Arquilla (1958). Sera which contain anti-Panton-Valentine leucocidin agglutinate the prepared red cells, often to a very high dilution, and this has provided a useful serological test for the diagnosis of staphy...

journal_title：Journal of clinical pathology

authors： TOWERS AG

更新日期：1961-03-01 00:00:00

abstract：:Although the UK National Institute for Health and Care Excellence guidelines recommend that in patients with biopsy-proven invasive lobular carcinoma (ILC), preoperative MRI scan is considered, the accuracy of diagnosis of ILC in core biopsy of the breast has not been previously investigated. Eleven pathology laborato...

journal_title：Journal of clinical pathology

authors： Naidoo K,Beardsley B,Carder PJ,Deb R,Fish D,Girling A,Hales S,Howe M,Wastall LM,Lane S,Lee AH,Philippidou M,Quinn C,Stephenson T,Pinder SE

更新日期：2016-12-01 00:00:00

abstract：AIM:To determine the prognostic significance and clinical relevance of cathepsin D detected by immunocytochemical assays (ICAs) in breast carcinomas. METHODS:151 patients presenting with palpable or impalpable breast carcinomas and who had not received any kind of adjuvant chemotherapy or endocrine therapy who were op...

journal_title：Journal of clinical pathology

authors： Charpin C,Garcia S,Bouvier C,Martini F,Lavaut M,Allasia C,Bonnier P,Andrac L

更新日期：1997-07-01 00:00:00