Loss of heterozygosity of the BRCA1 and FHIT genes in patients with sporadic breast cancer from Southern Brazil.

abstract：AIMS:The authors previously demonstrated that nasal mucus cyclic adenosine 3', 5'-monophosphate (cAMP) and cyclic 3', 5'-guanosine monophosphate (cGMP) were lower in patients with smell and taste dysfunction than in normal individuals. To learn more about these differences this study related levels of nasal mucus cAMP ...

journal_title：Journal of clinical pathology

authors： Henkin RI,Velicu I

更新日期：2012-05-01 00:00:00

abstract：:A patient with hyperparathyroidism due to a parathyroid adenoma was found to have metastatic medullary carcinoma in lymph nodes close to the thyroid gland. The finding of normal calcitonin and parathormone concentrations after removal of the adenoma suggested that the parathyroid lesion was not the result of the hypoc...

journal_title：Journal of clinical pathology

authors： MacGillivray JB,Anderson CJ

更新日期：1971-12-01 00:00:00

abstract：:Nasal biopsy findings in malignant histiocytosis presenting clinically as lethal midline granuloma are characterised by necrosis and infiltration of atypical histiocytic cells with a diffuse positive reaction for non-specific esterase. This cellular character was common to midline malignant reticulosis, and midline ma...

journal_title：Journal of clinical pathology

authors： Aozasa K

更新日期：1982-06-01 00:00:00

abstract：AIMS:To evaluate and compare the long term prognostic value of the WHO classification and the computerised multivariate morphometrical D score in endometrial hyperplasia. To test the reproducibility of the D score in two different centres. METHODS:Histopathological WHO classification and computerised morphometrical an...

journal_title：Journal of clinical pathology

authors： Orbo A,Baak JP,Kleivan I,Lysne S,Prytz PS,Broeckaert MA,Slappendel A,Tichelaar HJ

更新日期：2000-09-01 00:00:00

abstract：:The assessment of emphysema in human lungs has traditionally been based on observations made on whole lung slices. These methods are inappropriate for the study of early emphysema, because as much as 75% of the alveolar wall surface area may have been lost by the time airspaces are visible to the naked eye. A new, aut...

journal_title：Journal of clinical pathology

authors： Gillooly M,Lamb D,Farrow AS

更新日期：1991-12-01 00:00:00

abstract：:Sera from 20 cases of toxoplasmic lymphadenopathy were examined by an enzyme linked immunosorbent assay toxoplasma IgG avidity (ELISA) at two laboratories. The results obtained were largely in agreement and showed that sera from patients with acute infection had low avidity IgG (30% or less), whereas sera from patient...

journal_title：Journal of clinical pathology

authors： Joynson DH,Payne RA,Rawal BK

更新日期：1990-12-01 00:00:00

abstract：AIMS:Dysfunctional prothrombin residue Arg596 associated mutation has been found to precipitate venous thromboembolism (VTE). In the current study we investigated the prevalence of Arg596 associated mutations in Chinese patients with VTE and explored the functional impact of Arg596Gln mutation on coagulation function i...

journal_title：Journal of clinical pathology

authors： Wu X,Li L,Ding Q,Wang X,Wu F,Wu W

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:Intraduct papillary mucinous neoplasm (IPMN) is a pancreatic tumour that is often associated with chronic pancreatitis (CP) in the surrounding pancreas. Type 1 autoimmune pancreatitis (AIP) is a fibro-inflammatory condition with characteristic histological features and prominent IgG4+ plasma cells and is par...

journal_title：Journal of clinical pathology

authors： Bateman AC,Culver EL,Sommerlad M,Chetty R

更新日期：2013-08-01 00:00:00

abstract：:Sentinel lymph node biopsy is a novel method for the surgical management of patients with cervical cancer. Sentinel nodes have a higher chance of harbouring metastases than non-sentinel nodes. Assessment of sentinel nodes provides an opportunity to stage patients intraoperatively and avoid complete pelvic lymph node d...

journal_title：Journal of clinical pathology

authors： Rasty G,Hauspy J,Bandarchi B

更新日期：2009-12-01 00:00:00

abstract：:The air of three hospital wards was examined frequently for staphylococci for a period of nearly four years using slit samplers. ;Broadcasts' of staphylococci into the air were observed with the air count rising well above the mean of 0.2 staphylococcal particle per cubic foot and these broadcasts often appeared to be...

journal_title：Journal of clinical pathology

authors： Noble WC

更新日期：1962-11-01 00:00:00

abstract：:This report describes the case of a 76 year old man who suffered from febrile ulceronecrotic Mucha-Habermann disease (FUMHD). Despite this patient's typical clinical and histological findings, the fulminating course led to death. Polymerase chain reaction (PCR) analysis of the skin lesions showed that the infiltrating...

journal_title：Journal of clinical pathology

authors： Miyamoto T,Takayama N,Kitada S,Hagari Y,Mihara M

更新日期：2003-10-01 00:00:00

abstract：:This report describes a case of mucinous carcinoma and Müllerian metaplasia arising within an appendiceal duplication cyst found incidentally during an emergency Caesarian section. Intestinal duplication cysts are rare and although there are occasional reports of malignant transformation, this is the first case where ...

journal_title：Journal of clinical pathology

authors： Sington JD,Warren BF,Manek S

更新日期：2002-07-01 00:00:00

abstract：:Results of blood culture examination using the radiometric (Bactec-460) system for one year showed no overall improvement compared with those of the previous three years when a manual system with early blind subculture was used. The isolates from the manual system were available more often on solid media, 24 hours ear...

journal_title：Journal of clinical pathology

authors： Ganguli LA,Keaney MG,Hyde WA,Fraser SB

更新日期：1985-10-01 00:00:00

abstract：:The neutrophil shape change response to a chemotactic formylpeptide was assessed. Neutrophil bipolar shape formation (BSF) was also simultaneously assessed with a Boyden chamber-based neutrophil migration assay. Both assays were precise and relatively reproducible; the average coefficient of variation for the BSF assa...

journal_title：Journal of clinical pathology

authors： Lord RA,Roath S

更新日期：1990-04-01 00:00:00

abstract：AIM:To determine the prognostic significance and clinical relevance of cathepsin D detected by immunocytochemical assays (ICAs) in breast carcinomas. METHODS:151 patients presenting with palpable or impalpable breast carcinomas and who had not received any kind of adjuvant chemotherapy or endocrine therapy who were op...

journal_title：Journal of clinical pathology

authors： Charpin C,Garcia S,Bouvier C,Martini F,Lavaut M,Allasia C,Bonnier P,Andrac L

更新日期：1997-07-01 00:00:00

abstract：:The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on ...

journal_title：Journal of clinical pathology

authors： NOBLE WC,WILLIAMS RE,JEVONS MP,SHOOTER RA

更新日期：1964-01-01 00:00:00

abstract：:This paper describes the value in diagnosis and the clinical implications of the detection of pneumococcal antigen in patients with lobar pneumonia. Ninety-eight patients with lobar pneumonia were investigated. Pneumococcal antigen was detected by counter-current immunoelectrophoresis in the sputum of 79% of patients ...

journal_title：Journal of clinical pathology

authors： Tugwell P,Greenwood BM

更新日期：1975-02-01 00:00:00

abstract：:The applicability of a hapten-antihapten sandwich technique incorporating a monoclonal antihapten bridge antibody to localisation of tissue antigen is described. The results show that the method is both versatile and selective and has the potential of being even more sensitive than currently used immunoperoxidase meth...

journal_title：Journal of clinical pathology

authors： Jasani B,Thomas DW,Williams ED

更新日期：1981-09-01 00:00:00

abstract：:The aim of this article is to provide knowledge of the origin of catecholamines and metabolites so that there can be an informed approach to the methods for biochemical screening for a possible phaeochromocytoma; The article includes a review of catecholamine and metadrenaline metabolism, with methods used in biochemi...

journal_title：Journal of clinical pathology

authors： Barron J

更新日期：2010-08-01 00:00:00

abstract：AIMS:To examine whether variations in pathology test requesting between different general practices can be accounted for by sociodemographic or other descriptive indicators of the practice. METHOD:This was a comparative analysis of requesting patterns across a range of pathology tests representing 95% of those request...

journal_title：Journal of clinical pathology

authors： Smellie WS,Galloway MJ,Chinn D,Gedling P

更新日期：2002-04-01 00:00:00

abstract：AIM:To evaluate the use of multimedia enhancements, using a computerised microscope, in the training of microscope skills. METHODS:The HOME microscope provides facilities to highlight features of interest in conjunction with either text display or aural presentation. A pilot study was carried out with 10 individuals, ...

journal_title：Journal of clinical pathology

authors： Gray E,Duvall E,Sprey J,Bird CC

更新日期：1998-04-01 00:00:00

abstract：:A recently developed procedure, that has been shown to be suitable for detailed immunohistological analysis, has been used to prepare cryostat sections of bone marrow to investigate whether enzyme-histochemical techniques are also feasible on such material. A selected group of enzymes, some of which are inhibited or d...

journal_title：Journal of clinical pathology

authors： Chilosi M,Pizzolo G,Janossy G,Bofill M,Fiore-Donati L

更新日期：1982-11-01 00:00:00

abstract：:Serum haptoglobin levels have been studied in patients with a number of haemolytic disorders. In general, serum haptoglobins were low in patients with increased haemolysis. Values were reduced irrespective of whether haemolysis occurred intravascularly or extravascularly. The reduction was related to the amount of hae...

journal_title：Journal of clinical pathology

authors： Owen JA,de Gruchy GC,Smith H

更新日期：1960-11-01 00:00:00

abstract：:A new staining method was developed for the detection of inclusions of Chlamydia psittaci and Chlamydia trachomatis inclusions in cell cultures. Using a combination of methyl green and neutral red stains and washing at pH 5.0, inclusions were stained red while cell cytoplasm was pale pink and cell nuclei were pale gre...

journal_title：Journal of clinical pathology

authors： Woodland RM,Malam J,Darougar S

更新日期：1982-06-01 00:00:00

abstract：:A 19 year old man presented with unilateral testicular swelling and pain. An initial diagnosis of epididymo-orchitis was modified to a presumed testicular neoplasm following ultrasonography. The final diagnosis of isolated testicular vasculitis was established following histological examination of the orchidectomy spe...

journal_title：Journal of clinical pathology

authors： Warfield AT,Lee SJ,Phillips SM,Pall AA

更新日期：1994-12-01 00:00:00

abstract：AIMS:Meticillin-resistant Staphylococcus aureus (MRSA) strains isolated in Tawam Hospital, a tertiary care hospital in the United Arab Emirates, were examined in order to understand the reasons for a doubling of its incidence between 2003 and 2008 while maintaining the same infection control measures. METHODS:All cons...

journal_title：Journal of clinical pathology

authors： Sonnevend Á,Blair I,Alkaabi M,Jumaa P,Al Haj M,Ghazawi A,Akawi N,Jouhar FS,Hamadeh MB,Pál T

更新日期：2012-02-01 00:00:00

abstract：:A 43-year-old man, admitted with a swollen right thigh, was diagnosed with a deep vein thrombosis. On day 6 he became septic. A CT scan demonstrated a right-sided hydronephrosis and a large retroperitoneal collection. Blood cultures and perinephric pus grew Escherichia coli resistant to amoxicillin only. On day 12 a v...

journal_title：Journal of clinical pathology

authors： Alleyne SA,Bukhari SS,Fraser M,Spiers P

更新日期：2010-04-01 00:00:00

abstract：:A method for the simultaneous labelling of terminal deoxynucleotidyl transferase (TdT) and membrane antigens is described. TdT is visualised in the cell nucleus with the peroxidase-antiperoxidase (PAP) method, and the immunogold method is used in combination with monoclonal antibodies against membrane antigens. The mo...

journal_title：Journal of clinical pathology

authors： Tavares de Castro J,San Miguel JF,Soler J,Catovsky D

更新日期：1984-06-01 00:00:00

abstract：:Twenty five specimens of branchial cyst from the same number of patients have been examined. On staining with haematoxylin and eosin a consistent finding was that the mural lymphoid follicles were always aligned with their mantle zones towards the luminal epithelium. With conventional staining lymphatic sinuses were n...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R

更新日期：1985-07-01 00:00:00

abstract：:Automation in clinical chemistry is a powerful tool. Like most innovations it is posing many questions as well as resolving some. Its use in population screening has led to questioning the validity of the old system of ;normal values' and to the search for better methods of indicating the significance of laboratory te...

journal_title：Journal of clinical pathology

authors： Wilson JM

更新日期：1973-08-01 00:00:00