An immunohistochemical study of branchial cysts.

abstract：:A case of Cryptococcus neoformans meningitis is described in an HIV negative patient with undiagnosed systemic sarcoidosis. The patient presented with signs of meningitis together with generalised lymphadenopathy and hepatosplenomegaly. Cryptococcal meningitis was diagnosed on lumbar puncture. She was treated with int...

journal_title：Journal of clinical pathology

authors： Botha RJ,Wessels E

更新日期：1999-12-01 00:00:00

abstract：:The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on ...

journal_title：Journal of clinical pathology

authors： NOBLE WC,WILLIAMS RE,JEVONS MP,SHOOTER RA

更新日期：1964-01-01 00:00:00

abstract：BACKGROUND:A previous survey has highlighted the fact that most individuals in chemical pathology identifiable from specialist society membership failed to publish material in Medline cited journals during a five year period. It could be considered that published research that is not cited in other work is not useful u...

journal_title：Journal of clinical pathology

authors： Reynolds TM,Wierzbicki AS

更新日期：2004-04-01 00:00:00

abstract：:Muscle biopsy samples were analysed from five control subjects, four patients with mild to moderate fibre atrophy and four patients with severe atrophy. Patchy increase in lipid was noted with oil red O staining but there was no consistent association of lipid with selective fibre types. Ultrastructural studies demons...

journal_title：Journal of clinical pathology

authors： Sunnasy D,Cairns SR,Martin F,Slavin G,Peters TJ

更新日期：1983-07-01 00:00:00

abstract：:A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discusse...

journal_title：Journal of clinical pathology

authors： Burns GF,Cawley JC,Flemans RJ,Higgy KE,Worman CP,Barker CR,Roberts BE,Hayhoe FG

更新日期：1977-10-01 00:00:00

abstract：:Staining with naphthol AS phosphate and Fast Blue BB salt has been used for the estimation of neutrophil alkaline phosphatase (NAP) scores in patients with chronic granulocytic leukaemia (CGL). The very low scores found at diagnosis rise when the disease is treated, and there is some inverse correlation between the NA...

journal_title：Journal of clinical pathology

authors： Spiers AS,Liew A,Baikie AG

更新日期：1975-07-01 00:00:00

abstract：:Bone marrow aspirates and biopsy specimens were taken at diagnosis from 51 patients with acute myeloid leukaemia (AML). The diagnosis was based on morphological and cytochemical analyses, and the leukaemias were classified by FAB criteria. A considerable difference was observed between the results of bone marrow aspir...

journal_title：Journal of clinical pathology

authors： Islam A,Frisch B,Henderson ES

更新日期：1989-03-01 00:00:00

abstract：:An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment. ...

journal_title：Journal of clinical pathology

authors： Canning DM,Crane RS,Huntsman RG,Yawson GI

更新日期：1972-04-01 00:00:00

abstract：:The effect of temperature, time of storage, and presence of air bubbles in specimens for blood gas analysis was studied. The results show that air bubbles in a 10% proportion are undesirable because of significant elevation in the PO2, and the storage of anaerobic blood samples at room temperature (25 degrees C) is ac...

journal_title：Journal of clinical pathology

authors： Madiedo G,Sciacca R,Hause L

更新日期：1980-09-01 00:00:00

abstract：:An enzyme immunoassay technique based on the direct detection of Chlamydia trachomatis antigen in urethral or cervical swabs was used for the rapid diagnosis of chlamydial genital infection. Urethral and cervical samples from 140 patients were tested in parallel by enzyme immunoassay and cell culture using iodine stai...

journal_title：Journal of clinical pathology

authors： Mumtaz G,Mellars BJ,Ridgway GL,Oriel JD

更新日期：1985-07-01 00:00:00

abstract：AIMS:We aimed to study epidermal growth factor receptor (EGFR) expression in surgically resected pancreatic ductal adenocarcinomas (PDACs) by immunohistochemistry and their relationship to clinicopathological features, cell proliferation and cell adhesion protein expression. METHODS:A total of 99 PDACs were analysed o...

journal_title：Journal of clinical pathology

authors： Handra-Luca A,Hammel P,Sauvanet A,Lesty C,Ruszniewski P,Couvelard A

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:RCAS1 (receptor binding cancer antigen expressed on SiSo cells) is a tumour associated antigen. It is involved in immune evasion by tumour cells, by binding to receptors on cells involved in the immune response, such as T cells and natural killer cells, and inducing apoptosis. High expression of RCAS1 has be...

journal_title：Journal of clinical pathology

authors： Leelawat K,Watanabe T,Nakajima M,Tujinda S,Suthipintawong C,Leardkamolkarn V

更新日期：2003-10-01 00:00:00

abstract：:Factor VII levels have been measured in 100 patients with liver disease following parenteral vitamin K1 therapy. There was good agreement between specific factor VII measurements and the one-stage prothrombin time apart from six patients with compensated cirrhosis in whom the prothrombin time was prolonged despite the...

journal_title：Journal of clinical pathology

authors： Green G,Poller L,Thomson JM,Dymock IW

更新日期：1976-11-01 00:00:00

abstract：AIMS:Marked thrombocytosis is uncommon in chronic myelogenous leukaemia (CML) but may be associated with mutation of JAK2 V617F, calreticulin (CALR) and/or phospho-STAT5 (p-STAT5) activation in other myeloproliferative neoplasms (MPNs), particularly essential thrombocythaemia (ET). We investigated the JAK2 V617F, CALR ...

journal_title：Journal of clinical pathology

authors： Turakhia SK,Murugesan G,Cotta CV,Theil KS

更新日期：2016-08-01 00:00:00

abstract：AIMS:The aim of the present study was to immunohistochemically investigate the expression and prognostic significance of putative cancer stem cell markers CD117 (c-kit), CD34, CD20 and CD15 in a cohort of patients with primary choroidal and ciliary body melanoma. METHODS:The immunohistochemical expression of these mar...

journal_title：Journal of clinical pathology

authors： Lukenda A,Dotlic S,Vukojevic N,Saric B,Vranic S,Zarkovic K

更新日期：2016-03-01 00:00:00

abstract：:A case of florid rheumatoid heart disease with complete heart block is described, and the histopathology of the atrioventricular conducting tissue is described in detail. ...

journal_title：Journal of clinical pathology

authors： Harris M

更新日期：1970-10-01 00:00:00

abstract：:A young woman presented with bilateral ovarian tumours. Multiple sections of each tumour were shown to many pathologists for consultation; some considered the tumours to be borderline, whereas others thought that one or both of them was malignant. Morphometry showed that the numerical classification probabilities for ...

journal_title：Journal of clinical pathology

authors： Baak JP,Van der Ley G

更新日期：1984-10-01 00:00:00

abstract：:Transmembrane serine protease 2 is encoded by the TMPRSS2 gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the inactive zymogen form. A fusion gene between the TMPRSS2 gene and ERG (erythroblast-specific-related gene), an oncogenic transcription factor, is the most c...

journal_title：Journal of clinical pathology

authors： Thunders M,Delahunt B

更新日期：2020-12-01 00:00:00

abstract：:Results of blood culture examination using the radiometric (Bactec-460) system for one year showed no overall improvement compared with those of the previous three years when a manual system with early blind subculture was used. The isolates from the manual system were available more often on solid media, 24 hours ear...

journal_title：Journal of clinical pathology

authors： Ganguli LA,Keaney MG,Hyde WA,Fraser SB

更新日期：1985-10-01 00:00:00

abstract：AIM:To investigate the tissue specificity of a novel monoclonal antibody raised to a tissue fraction of normal human liver and which identified certain cells of gastric and duodenal mucosa. METHODS:A total of 155 samples of various tissues obtained from 100 surgical specimens were fixed in cold ethanol-paraformaldehyd...

journal_title：Journal of clinical pathology

authors： Hughes NR,Bhathal PS,Francis DM

更新日期：1994-01-01 00:00:00

abstract：AIM:To examine lymphocyte subsets in patients with myelodysplastic syndromes (MDS); and to correlate immunohistological variables with prognosis. METHODS:Bone marrow trephine biopsy specimens from 65 patients with MDS were immunophenotyped using a panel of antibodies. A minimum of 1000 cells from representative areas ...

journal_title：Journal of clinical pathology

authors： Hilbe W,Eisterer W,Schmid C,Starz I,Silly H,Duba C,Ludescher C,Thaler J

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Although in vitro breast cancer models have demonstrated a role for protein kinase C (PKC) alpha and delta isoforms in endocrine insensitivity and resistance respectively, there is currently little clinical evidence to support these observations. AIMS:To define the pattern of PKC alpha and delta expression ...

journal_title：Journal of clinical pathology

authors： Assender JW,Gee JM,Lewis I,Ellis IO,Robertson JF,Nicholson RI

更新日期：2007-11-01 00:00:00

abstract：:This is a retrospective study of the results of 4,642 blood cultures taken from 2,190 patients from 1960 to 1967 in one London hospital. The results suggested that an increased incidence of bacteraemias at this particular hospital was mainly due to the increase in the number of patients having blood cultures. Some of ...

journal_title：Journal of clinical pathology

authors： Crowley N

更新日期：1970-03-01 00:00:00

abstract：BACKGROUND:Clinical outcome in patients with diffuse large B cell lymphomas (DLBCL) is highly variable and poorly predictable. Microarray studies showed that patients with DLBCL with a germinal centre B cell-like (GCB) phenotype have a better prognosis than those with an activated B cell-like (ABC) phenotype. The BMI1 ...

journal_title：Journal of clinical pathology

authors： van Galen JC,Muris JJ,Oudejans JJ,Vos W,Giroth CP,Ossenkoppele GJ,Otte AP,Raaphorst FM,Meijer CJ

更新日期：2007-02-01 00:00:00

abstract：:Specimens of muscle were obtained from non-suppurating lesions of nine patients with tropical myositis. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure. Perimysial cells were also degenerate. Sections from two out of nine patients revealed intracellular vesicles,...

journal_title：Journal of clinical pathology

authors： Taylor JF,Fluck D,Fluck D

更新日期：1976-12-01 00:00:00

abstract：:Two patients are reported in whom initial misdiagnoses of medullary cancer or trabecular hyaline adenoma for papillary carcinoma were made. ...

journal_title：Journal of clinical pathology

authors： Andrew AC,Williamson JM

更新日期：1993-08-01 00:00:00

abstract：AIMS:Ki-67 is a prognostic marker in breast cancer; however, the use of the Ki-67 labelling index (LI) in clinical practice requires a consistent and easily accessible scoring method. The present study evaluated the use of the free internet-based image analysis program ImmunoRatio to score Ki-67 LI in breast cancer in ...

journal_title：Journal of clinical pathology

authors： Yeo MK,Kim HE,Kim SH,Chae BJ,Song BJ,Lee A

更新日期：2017-08-01 00:00:00

abstract：:A sensitive gas chromatography-mass spectrometric method was used to measure the generation in whole blood of leukotriene B4 (LTB4), a potent stimulator of neutrophil chemotaxis, in eight patients with chronic granulocytic leukaemia (CGL) and 12 healthy controls. LTB4 was detectable in unstimulated samples from all th...

journal_title：Journal of clinical pathology

authors： Reilly IA,Knapp HR,Fitzgerald GA

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Ewing's sarcoma and peripheral primitive neuroectodermal tumour (pPNET) are now regarded as two morphological ends of a spectrum of neoplasms, characterised by a t(11;22) or other related chromosomal translocation involving the EWS gene on chromosome 22 and referred to as Ewing family of tumours (EFTs). EFTs...

journal_title：Journal of clinical pathology

authors： McCluggage WG,Sumathi VP,Nucci MR,Hirsch M,Dal Cin P,Wells M,Flanagan AM,Fisher C

更新日期：2007-06-01 00:00:00

abstract：AIMS:To describe the prostatic adenectomy specimens of six patients with symptomatic benign prostatic hyperplasia (BPH) who failed to respond to long term treatment with a 5-alpha-reductase inhibitor, finasteride. METHODS:Histological sections from six cases of BPH who had been treated with finasteride were investigat...

journal_title：Journal of clinical pathology

authors： Montironi R,Valli M,Fabris G

更新日期：1996-04-01 00:00:00