Frozen section simulation of trabecular adenoma and medullary cancer by papillary thyroid carcinoma.

abstract：AIMS:To clarify a clinical entity of juvenile polyposis of the stomach compared with generalised juvenile gastrointestinal polyposis. METHODS:The clinicopathological features of juvenile polyposis dominantly involving the stomach at initial presentation were reviewed in 12 patients (three new patients and nine from th...

journal_title：Journal of clinical pathology

authors： Hizawa K,Iida M,Yao T,Aoyagi K,Fujishima M

更新日期：1997-09-01 00:00:00

abstract：AIMS:Ki-67 is a prognostic marker in breast cancer; however, the use of the Ki-67 labelling index (LI) in clinical practice requires a consistent and easily accessible scoring method. The present study evaluated the use of the free internet-based image analysis program ImmunoRatio to score Ki-67 LI in breast cancer in ...

journal_title：Journal of clinical pathology

authors： Yeo MK,Kim HE,Kim SH,Chae BJ,Song BJ,Lee A

更新日期：2017-08-01 00:00:00

abstract：:The effect of radiotherapy on normal buccal mucosa was investigated using the quantitative techniques of cytomorphology (measurement of nuclear and cytoplasmic area) and DNA cytophotometry. These techniques were applied to smears obtained before, during, and after irradiation. Nuclear area and cytoplasmic area increas...

journal_title：Journal of clinical pathology

authors： Ogden GR,Cowpe JG,Green MW

更新日期：1989-09-01 00:00:00

abstract：:Metabolic balance studies for iron have been carried out on 24 apparently healthy elderly people (11 men and 13 women) aged 69.7 to 85.5 years living in their own homes and eating self selected diets. Several biochemical and haematological indices of iron state were also measured. The mean daily iron intake was 176 mu...

journal_title：Journal of clinical pathology

authors： Bunker VW,Lawson MS,Clayton BE

更新日期：1984-12-01 00:00:00

abstract：:A panel of three monoclonal antibodies were used in an immunoalkaline phosphatase staining method on a series of serous effusion samples from cases of mesothelioma, lung carcinoma, and benign disease. The antibodies used were anti-carcinoembryonic (CEA) antigen, Ca, and anti-human milk fat globule membrane antigen. An...

journal_title：Journal of clinical pathology

authors： Ghosh AK,Butler EB

更新日期：1987-12-01 00:00:00

abstract：:Tissue microarray (TMA) is an established and valuable tool, particularly in translational research and clinical trials, allowing resource-efficient use, and high-throughput profiling, of large numbers of tumours. Despite this, there is little evidence, or guidance, on the optimum manufacture, use and assessment of TM...

journal_title：Journal of clinical pathology

authors： Pinder SE,Brown JP,Gillett C,Purdie CA,Speirs V,Thompson AM,Shaaban AM,Translational Subgroup of the NCRI Breast Clinical Studies Group.

更新日期：2013-03-01 00:00:00

abstract：:The applicability of a recently developed non-radioactive DNA labelling and detection method, which uses the digoxigenin (DIG) enzyme linked immunosorbent assay (ELISA) system, for the detection of viral infections in pathology specimens by in situ hybridisation, was examined. Its efficacy was compared with that of bi...

journal_title：Journal of clinical pathology

authors： Furuta Y,Shinohara T,Sano K,Meguro M,Nagashima K

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:EpCAM is an adhesion molecule of the basolateral membranes in a variety of epithelial cells. Over-expression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. AIMS:To assess the prognostic value of EpCAM in urothelial ...

journal_title：Journal of clinical pathology

authors： Brunner A,Prelog M,Verdorfer I,Tzankov A,Mikuz G,Ensinger C

更新日期：2008-03-01 00:00:00

abstract：:A case of Legionella pneumophila pneumonia with rhabdomyolysis-induced acute tubulointerstitial nephritis (ATIN) and prolonged renal dysfunction is presented. The patient was a 54-year-old man, admitted with high-grade fever, ataxia and muscle dysfunction; chest roentgenogram showed multilobular infiltrations. L pneum...

journal_title：Journal of clinical pathology

authors： Shimura C,Saraya T,Wada H,Takata S,Mikura S,Yasutake T,Kato J,Kato A,Yamamoto M,Watanabe M,Yokoyama T,Kurai D,Ishii H,Aoshima M,Yamada A,Goto H

更新日期：2008-09-01 00:00:00

abstract：AIMS:To test whether a hypoacidic environment may potentially "stress" Helicobacter pylori DNA, encouraging the emergence of strain variation. METHODS:This hypothesis was tested by inducing prolonged hypoacidity with omeprazole, a potent antisecretory drug. The genomic DNA of H pylori was studied by electrophoretic se...

journal_title：Journal of clinical pathology

authors： Fraser AG,Bickley J,Owen RJ,Pounder RE

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:The disorders associated with metabolic syndrome (MS) can lead to renal disease. IgA nephropathy is the most common form of glomerulonephritis, and many patients with this disorder progress to renal failure. AIMS:To identify the effect of MS on IgA nephropathy by retrospectively comparing patients who had I...

journal_title：Journal of clinical pathology

authors： Wang L,Zhang Y,Chen S,Chen J,Zhuang Y,Chen J

更新日期：2010-08-01 00:00:00

abstract：AIMS:We aimed to study epidermal growth factor receptor (EGFR) expression in surgically resected pancreatic ductal adenocarcinomas (PDACs) by immunohistochemistry and their relationship to clinicopathological features, cell proliferation and cell adhesion protein expression. METHODS:A total of 99 PDACs were analysed o...

journal_title：Journal of clinical pathology

authors： Handra-Luca A,Hammel P,Sauvanet A,Lesty C,Ruszniewski P,Couvelard A

更新日期：2014-04-01 00:00:00

abstract：:The possible use of sodium hypochlorite solution buffered to pH 7.6 and containing 100 ppm available chlorine (avCl) for disinfecting fibrescopes was investigated. A flexible fibrescope experimentally contaminated with Pseudomonas putida, Mycobacterium fortuitum, or Bacillus subtilis spores was effectively disinfected...

journal_title：Journal of clinical pathology

authors： Coates D,Death JE

更新日期：1982-03-01 00:00:00

abstract：AIMS:The IHC4+C score combines assessment of oestrogen receptor (ER), progesterone receptor (PgR), HER2 and Ki67 with clinicopathological parameters to identify the risk of distant disease recurrence in patients with breast cancer, so, aiding treatment decision-making on adjuvant chemotherapy. Despite low cost and wide...

journal_title：Journal of clinical pathology

authors： Dodson A,Zabaglo L,Yeo B,Miller K,Smith I,Dowsett M

更新日期：2016-02-01 00:00:00

abstract：:One hundred and two bone marrow samples were analysed by histological and immunohistochemical methods for neurone specific enolase (NSE). The biopsies were performed to determine the extent of bone marrow disease in 84 neuroblastomas, nine embryonal rhabdomyosarcomas, five Ewing's sarcomas, two cases of Hodgkin's dise...

journal_title：Journal of clinical pathology

authors： Caillaud JM,Martinez-Madrigal F,Hartmann O,Carlu C

更新日期：1991-04-01 00:00:00

abstract：:A radioimmunoassay for human growth hormone using activated charcoal is described and its precision, accuracy, and sensitivity are defined. Results are presented for growth hormone measurements in plasma obtained during hypoglycaemia induced with insulin in patients of short stature and during glucose tolerance tests ...

journal_title：Journal of clinical pathology

authors： Thomas FJ,Lloyd HM,Thomas MJ

更新日期：1972-09-01 00:00:00

abstract：AIMS/BACKGROUND:Telomerase is an enzyme that is expressed in most human neoplasms and is associated with tumour immortality. Determination of the point in neoplastic transformation at which telomerase is expressed may aid the understanding of tumour pathogenesis and progression. Despite numerous reports on telomerase, ...

journal_title：Journal of clinical pathology

authors： Kleinschmidt-DeMasters BK,Hashizumi TL,Sze CI,Lillehei KO,Shroyer AL,Shroyer KR

更新日期：1998-04-01 00:00:00

abstract：:Circulating immune complexes have been detected in the sera of 24 Nigerian children with acute poststreptococcal glomerulonephritis using two methods. There was a significant correlation between levels of soluble complexes, detected in samples taken from patients in the oliguric phase of acute nephritis, and severity ...

journal_title：Journal of clinical pathology

authors： Onyewotu II,Mee J

更新日期：1978-09-01 00:00:00

abstract：AIM:To investigate morphological changes in the tumour vessel adventitia, particularly the distribution of vascular adventitial fibroblastic cells (VAFCs)--namely, CD34 positive fibroblastic cells just outside the vascular media--in diffuse-type gastric carcinomas. METHOD:In total, 18 surgically resected advanced typi...

journal_title：Journal of clinical pathology

authors： Nakayama H,Enzan H,Miyazaki E,Kuroda N,Toi M,Hiroi M,Yasui W

更新日期：2004-09-01 00:00:00

abstract：:Veno-occlusive disease of the liver with clinical and pathological features similar to those of the condition occurring in the Caribbean is described in a young woman resident in Britain. The diagnosis was made from liver biopsies and hepatic venography and was confirmed at necropsy. Small amounts of pyrroliziding alk...

journal_title：Journal of clinical pathology

authors： McGee J,Patrick RS,Wood CB,Blumgart LH

更新日期：1976-09-01 00:00:00

abstract：:Four strains of Corynebacterium diphtheriae were sent to UK participants in the UK National External Microbiological Quality Assessment Scheme, who were asked to examine the strains for toxin production by in vitro methods. Laboratories achieved 162/176 (92%) and 160/175 (91%) correct results with two rapid toxin prod...

journal_title：Journal of clinical pathology

authors： Snell JJ,Demello JV,Gardner PS,Kwantes W,Brooks R

更新日期：1984-07-01 00:00:00

abstract：:This study was undertaken to determine the interrelations between clinico-biochemical parameters and hepatic morphology in markedly obese patients. One hundred and sixty-six women and 52 men comprise this series. There was a statistically significant association of carbohydrate metabolism disturbance with increasing a...

journal_title：Journal of clinical pathology

authors： Manes JL,Taylor HB,Starkloff GB

更新日期：1973-10-01 00:00:00

abstract：:One hundred catalase-positive, coagulase-negative, Gram-positive cocci isolated in significant numbers from the urine of patients with urinary tract infections, provisionally subdivided by their sensitivity to nonoviocin, were classified according to a slightly model version of Baird-Parker's schemes (1965 and 1972). ...

journal_title：Journal of clinical pathology

authors： Meers PD,Whyte W,Sandys G

更新日期：1975-04-01 00:00:00

abstract：:Experience after 18 months' work with the SMA-4 system of multiple analysis for routine haematology is described, as well as the modifications to the machine which have been made for smoother operation. ...

journal_title：Journal of clinical pathology

authors： Green AE,Middleton VL,Prentis KG,Signy AG

更新日期：1969-01-01 00:00:00

abstract：AIMS:The aim of this study was to develop a computer-aided diagnosis (CADx) system for identifying breast pathology. METHODS:Two sets of 100 consecutive core needle biopsy (CNB) specimens were collected for test and validation studies. All 200 CNB specimens were stained with antibodies targeting oestrogen receptor (ER...

journal_title：Journal of clinical pathology

authors： Maeda I,Kubota M,Ohta J,Shinno K,Tajima S,Ariizumi Y,Doi M,Oana Y,Kanemaki Y,Tsugawa K,Ueno T,Takagi M

更新日期：2017-12-01 00:00:00

abstract：:Two examples of intraplacental choriocarcinoma are described. Both were small and had arisen in otherwise normal third trimester placentas. The covering mantle of many of the villi adjacent to the choriocarcinomas was formed, either focally or wholly, of neoplastic trophoblastic tissue: it is only at this stage of the...

journal_title：Journal of clinical pathology

authors： Fox H,Laurini RN

更新日期：1988-10-01 00:00:00

abstract：:The isotopic estimation of the cortisol secretion rate in man is now an accepted and reliable method of assaying adrenal cortical function.Seven years' experience with its clinical use is reviewed and some practical aspects of technique are considered. The mean normal resting cortisol secretion rate is 16.2 +/- 5.7 mg...

journal_title：Journal of clinical pathology

authors： COPE CL,PEARSON J

更新日期：1965-01-01 00:00:00

abstract：AIMS:To assess the clinical efficacy of diagnostic procedures for breast cancer at a teaching hospital using internal auditing tools and quality control measures. METHODS:A retrospective assessment of 500 patients who underwent core needle biopsy (wide-bore needle biopsy; WBN) of palpable or non-palpable breast nodes ...

journal_title：Journal of clinical pathology

authors： Verenhitach BD,Elias S,Patrocínio AC,Nazário AC,Waizberg A

更新日期：2011-10-01 00:00:00

abstract：AIMS:To determine how epithelial and stromal thymidine phosphorylase expression affects angiogenesis, rapid tumour growth, and decreased apoptotic activity in cervical cancer at varying stages of progression. METHODS:Epithelial and stromal thymidine phosphorylase expression, the microvessel count (reflected by factor ...

journal_title：Journal of clinical pathology

authors： Fujiwaki R,Hata K,Iida K,Maede Y,Koike M,Miyazaki K

更新日期：1999-08-01 00:00:00

abstract：:Inhibition of streptolysin O activity by cholesterol depends on the latter being in free form. The normal esterified and protein-bound cholesterol fractions in serum do not influence streptolysin O activity. However, high cholesterol levels in rabbits fed cholesterol with cholic acid were associated with an increased ...

journal_title：Journal of clinical pathology

authors： Watson KC,Rose TP,Kerr EJ

更新日期：1972-10-01 00:00:00