Pathological evidence of rhabdomyolysis-induced acute tubulointerstitial nephritis accompanying Legionella pneumophila pneumonia.

Abstract:

:A case of Legionella pneumophila pneumonia with rhabdomyolysis-induced acute tubulointerstitial nephritis (ATIN) and prolonged renal dysfunction is presented. The patient was a 54-year-old man, admitted with high-grade fever, ataxia and muscle dysfunction; chest roentgenogram showed multilobular infiltrations. L pneumophila was detected in his sputum and urine, by PCR and by culture, and L pneumophila pneumonia was diagnosed. Despite antimicrobial treatment, he developed renal failure and rhabdomyolysis. Renal biopsy showed the presence of myoglobin casts that occluded the distal tubuli and tubulointerstitial nephritis, leading to the diagnosis of rhabdomyolysis-induced ATIN. Renal function subsequently normalised, and he was discharged. This is believed to be the first pathological evidence of involvement of rhabdomyolysis in legionellosis-associated ATIN.

journal_name

J Clin Pathol

authors

Shimura C,Saraya T,Wada H,Takata S,Mikura S,Yasutake T,Kato J,Kato A,Yamamoto M,Watanabe M,Yokoyama T,Kurai D,Ishii H,Aoshima M,Yamada A,Goto H

doi

10.1136/jcp.2008.057000

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

1062-3

issue

9

eissn

0021-9746

issn

1472-4146

pii

jcp.2008.057000

journal_volume

61

pub_type

杂志文章,评审
  • Friend leukaemia integration-1 expression in malignant and benign tumours: a multiple tumour tissue microarray analysis using polyclonal antibody.

    abstract:BACKGROUND:Friend leukaemia integration-1 (FLI-1) antibody is a useful marker for Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET) and vascular tumours. However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT). AIM:To de...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.2006.039230

    authors: Mhawech-Fauceglia P,Herrmann FR,Bshara W,Odunsi K,Terracciano L,Sauter G,Cheney RT,Groth J,Penetrante R,Mhawech-Fauceglia P

    更新日期:2007-06-01 00:00:00

  • Changes in cytomorphology of childhood lymphoblastic leukaemia at the time of disease relapse. Childhood Leukaemia Working Party of the United Kingdom Medical Research Council.

    abstract:AIMS:Children in a United Kingdom national trial for relapsed non-B lymphoblastic leukaemia (ALL) had their diagnostic and relapse marrow cytomorphology compared to see what changes occur during the evolution of the disease. METHODS:Each relapse slide was assessed blindly for French American British (FAB) type and oth...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.48.11.1051

    authors: Lilleyman JS,Stevens RF,Hann IM,Gibson BE,Britton JA,Darbyshire PJ,Oakhill A

    更新日期:1995-11-01 00:00:00

  • Plasma biotin levels in children with burns and scalds.

    abstract::The plasma concentrations of biotin were measured for up to 49 days after injury in nine children with burns and scalds which involved from 12% to 50% of the surface area of the body. Biotin levels below the minimum of the control range were observed in eight of the nine injured children at some stage during the episo...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.29.1.58

    authors: Barlow GB,Dickerson JA,Wilkinson AW

    更新日期:1976-01-01 00:00:00

  • Evaluation of sensitivity of 10 diagnostic assays for Chlamydia trachomatis by use of a simple laboratory procedure.

    abstract:AIMS:To determine the sensitivity of commercially available diagnostic assays for Chlamydia trachomatis using a simple method. METHODS:Nine commercial assays and an "in-house" polymerase chain reaction (PCR) were evaluated using serial dilutions of a laboratory grown H serovar--four of them using a laboratory grown E ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.46.5.408

    authors: Thomas BJ,MacLeod EJ,Taylor-Robinson D

    更新日期:1993-05-01 00:00:00

  • Simultaneous acute inflammation in entopic and ectopic pancreas.

    abstract::The necropsy findings in an elderly woman, who had been treated with methyldopa and who had died during treatment for accidental hypothermia, showed acute periductal inflammation of obviously similar duration in an entopic pancreas in the wall of the jejunum and in the ectopic pancreas. This supports the hypothesis th...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.41.4.430

    authors: Benbow EW

    更新日期:1988-04-01 00:00:00

  • Hepatic myospherulosis complicating portal vein embolisation.

    abstract:AIMS:Myospherulosis is a rare condition characterised by sac-like structures containing spheroid bodies in cysts or cystic spaces in the tissue. This condition has not previously been reported in the liver. The association with previous portal vein embolisation using a mixture of butyl 2-cyanoacrylate and ethiodised oi...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.2003.11965

    authors: Lui PC,Luk IS,Lee CK,Lui YH,Leung CY,Choi CH

    更新日期:2004-02-01 00:00:00

  • Combined sputum hypermethylation and eNose analysis for lung cancer diagnosis.

    abstract:AIMS:The aim of this study is to explore DNA hypermethylation analysis in sputum and exhaled breath analysis for their complementary, non-invasive diagnostic capacity in lung cancer. METHODS:Sputum samples and exhaled breath were prospectively collected from 20 lung cancer patients and 31 COPD controls (Set 1). An add...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2014-202414

    authors: Hubers AJ,Brinkman P,Boksem RJ,Rhodius RJ,Witte BI,Zwinderman AH,Heideman DA,Duin S,Koning R,Steenbergen RD,Snijders PJ,Smit EF,Sterk PJ,Thunnissen E

    更新日期:2014-08-01 00:00:00

  • Immunocytological staining reactions of anti-carcinoembryonic antigen, Ca, and anti-human milk fat globule monoclonal antibodies on benign and malignant exfoliated mesothelial cells.

    abstract::A panel of three monoclonal antibodies were used in an immunoalkaline phosphatase staining method on a series of serous effusion samples from cases of mesothelioma, lung carcinoma, and benign disease. The antibodies used were anti-carcinoembryonic (CEA) antigen, Ca, and anti-human milk fat globule membrane antigen. An...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.40.12.1424

    authors: Ghosh AK,Butler EB

    更新日期:1987-12-01 00:00:00

  • Use of orcein in detecting hepatitis B antigen in paraffin sections of liver.

    abstract::This study has shown that different supplies/batches of orcein perform differently and may fail. The "natural" forms generally performed better although the most informative results were obtained with a "synthetic" product. Orcein dye solutions can be used soon after preparation and for up to 7 days without the need f...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.35.4.430

    authors: Kirkpatrick P

    更新日期:1982-04-01 00:00:00

  • Gonadal malignancy in 13 consecutive collected patients with disorders of sex development (DSD) from Semarang (Indonesia).

    abstract:AIMS:Caucasian patients with disorders of sex development (DSD) are at a high risk of developing germ cell cancer (GCC). GCC is prominent in young adults in Western countries, while the incidence is significantly lower in Asia. So far, the risk of GCC in Asian DSD patients is unknown. METHODS AND RESULTS:A detailed st...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2012-201062

    authors: Juniarto AZ,Setyawati BA,Miranti IP,Santosa A,Hersmus R,Stoop H,Cools M,Oosterhuis JW,Drop SL,Faradz SM,Looijenga LH

    更新日期:2013-03-01 00:00:00

  • Mixed lymphocyte reactions do not predict severity of graft versus host disease (GVHD) in HLA-DR compatible, sibling bone marrow transplants.

    abstract::Mixed lymphocyte reactions (MLRs) were measured in 25 HLA-A, B and DR compatible sibling bone marrow transplants. Only four of 25 MLRs were positive and in these the low reactivity was of doubtful clinical importance. There was no correlation between MLR and the subsequent development or severity of graft versus host ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.41.11.1155

    authors: Lim SH,Patton WN,Jobson S,Gentle TA,Baynham M,Franklin IM,Broughton BJ

    更新日期:1988-11-01 00:00:00

  • Histological and molecular diversity and heterogeneity of precancerous lesions associated with inflammatory bowel diseases.

    abstract:AIMS:Inflammatory bowel disease (IBD)-associated precancerous lesions may be adenomatous or non-adenomatous with various histomorphologies. We aim to validate the newly proposed classification, to explore the neoplastic nature of the non-adenomatous lesions and to elucidate the molecular mechanisms underlying the diffe...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2019-206247

    authors: Gui X,Köbel M,Ferraz JG,Iacucci M,Ghosh S,Liu S,Ou Y,Perizzolo M,Winkfein RJ,Rambau P,Demetrick DJ

    更新日期:2020-07-01 00:00:00

  • Lymphoid follicles in antral mucosa: immune response to Campylobacter pylori?

    abstract::The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastrit...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.42.12.1269

    authors: Stolte M,Eidt S

    更新日期:1989-12-01 00:00:00

  • Pathogenicity and virulence of coagulase negative staphylococci in relation to adherence, hydrophobicity, and toxin production in vitro.

    abstract:AIMS:To study the pathogenicity and virulence characteristics of Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus sapro-phyticus. METHODS:BALB/c mice were challenged intraperitoneally with graded doses of three strains belonging to each species. LD50s were measured for each strain. Haemolysi...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.47.8.743

    authors: Molnàr C,Hevessy Z,Rozgonyi F,Gemmell CG

    更新日期:1994-08-01 00:00:00

  • Evidence of novel pathogenic pathways for the formation of antigastric autoantibodies in Helicobacter pylori gastritis.

    abstract::Autoantibodies against gastric epithelial cells are detectable in up to 50% of patients with chronic, active Helicobacter pylori gastritis. Presence of autoantibodies against canalicular structures within human parietal cells (anticanalicular autoantibodies) correlate with gastric mucosa atrophy. It has been suggested...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.51.3.244

    authors: Faller G,Steininger H,Appelmelk B,Kirchner T

    更新日期:1998-03-01 00:00:00

  • Use of PCR in resolving diagnostic difficulties potentially caused by genetic variation of hepatitis B virus.

    abstract:AIMS:To assess the relevance of genetic variants of hepatitis B virus (HBV) and to demonstrate the usefulness of the polymerase chain reaction (PCR) in cases of HBV diagnostic difficulty. METHODS:Five serum samples from patients that presented diagnostic difficulty in routine laboratories were sent to a research labor...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.51.2.149

    authors: van Deursen FJ,Hino K,Wyatt D,Molyneaux P,Yates P,Wallace LA,Dow BC,Carman WF

    更新日期:1998-02-01 00:00:00

  • Validation of the Singapore nomogram for outcome prediction in breast phyllodes tumours in a large patient cohort.

    abstract:AIMS:To validate the Singapore nomogram for outcome prediction in breast phyllodes tumours in a large cohort of Singaporean patients, as previous validation studies were conducted on small numbers of patients. We also investigate the association of fibroadenomas and phyllodes tumours within a subset of our cohort. MET...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2017-204568

    authors: Chng TW,Gudi M,Lim SH,Li H,Tan PH

    更新日期:2018-02-01 00:00:00

  • PD-L1 expression is an unfavourable prognostic indicator in Asian renal cell carcinomas.

    abstract:BACKGROUND/AIMS:The programmed cell death receptor 1 (PD-1) checkpoint inhibitor, nivolumab, has been approved for the treatment of metastatic renal cell carcinoma (RCC). However, the understanding of the expression and distribution of PD ligand 1 (PD-L1) in the tumour immune microenvironment and its prognostic role in...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2019-206092

    authors: Yeong J,Zhao Z,Lim JCT,Li H,Thike AA,Koh VCY,Teh BT,Kanesvaran R,Toh CK,Tan PH,Khor LY

    更新日期:2020-08-01 00:00:00

  • Modification of Michaëlsson's method for the measurement of plasma total bilirubin.

    abstract::Michaëlsson's (1961) method for the measurement of plasma bilirubin concentration was found to be complicated by conjugated bilirubin. Delaying the addition of the accelerator, diphylline, corrected this fault. The method was calibrated using serum or plasma, since reconstituted protein solutions introduced large erro...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.22.4.439

    authors: Thompson RP

    更新日期:1969-07-01 00:00:00

  • My approach to atypical melanocytic lesions.

    abstract::Histological assessment of melanocytic naevi constitutes a substantial proportion of a dermatopathologist's daily workload. Although they may be excised for cosmetic reasons, most lesions encountered are clinically atypical and are biopsied or excised to exclude melanoma. Although dysplastic naevi are most often encou...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1136/jcp.2003.008516

    authors: Culpepper KS,Granter SR,McKee PH

    更新日期:2004-11-01 00:00:00

  • DNA-EIA to detect high and low risk HPV genotypes in cervical lesions with E6/E7 primer mediated multiplex PCR.

    abstract:BACKGROUND:Oncogenicity of human papillomavirus (HPV) DNA in premalignant and malignant uterine cervical diseases is mainly induced by E6/E7 open reading frame (ORF). The presence of an oncogenic HPV DNA may be a diagnostic marker for the detection of cytologically negative smears. AIMS:To evaluate an original polymer...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.51.1.38

    authors: Clavel C,Rihet S,Masure M,Chypre C,Boulanger JC,Quereux C,Birembaut P

    更新日期:1998-01-01 00:00:00

  • Myelofibrosis presenting as spinal cord compression.

    abstract::This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass. ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.56.2.154

    authors: Horwood E,Dowson H,Gupta R,Kaczmarski R,Williamson M

    更新日期:2003-02-01 00:00:00

  • Distribution of cervical intraepithelial neoplasia: are hysterectomy specimens sampled appropriately?

    abstract:AIM:To determine whether sampling the anterior and posterior cervical lips in hysterectomy specimens provides the best opportunity for detecting unsuspected cervical intraepithelial neoplasia (CIN). METHODS:The frequency with which CIN was identified at a range of positions on the anterior and posterior lips and left ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.48.4.323

    authors: Heatley M

    更新日期:1995-04-01 00:00:00

  • Multiple microcarcinoids in a patient with long standing ulcerative colitis.

    abstract::A male patient with a 17 year history of intractable ulcerative colitis of the entire type was treated by total proctocolectomy. Colonoscopy before surgery did not identify dysplasia. Histological examination of the resected colorectum revealed that, in addition to chronic inflammatory infiltrates, there were 21 areas...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.56.12.963

    authors: Matsumoto T,Jo Y,Mibu R,Hirahashi M,Yao T,Iida M

    更新日期:2003-12-01 00:00:00

  • Malakoplakia of the adrenal gland.

    abstract::The clinical and pathological features of a case of malakoplakia of the adrenal gland occurring in a woman with Escherichia coli infection are described. This lesion mimicked a neoplasm, the true diagnosis only being revealed by histological examination. The light and electron microscopic features are described and it...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.34.6.606

    authors: Benjamin E,Fox H

    更新日期:1981-06-01 00:00:00

  • Cytochemical reactions of normal and neoplastic lymphocytes.

    abstract::Rosetting and non-rosetting lymphocytes collected from normal individuals were stained for the presence of beta-glucuronidase, periodic-acid Schiff activity, gamma glutamyl transpeptidase, acid phosphatase, and alpha-naphthyl butyrate esterase. Lymphocytes which formed rosettes with sheep erythrocytes and non-rosette ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.30.7.653

    authors: Davey FR,Huntington SJ,Maccallum J,Macmath JM

    更新日期:1977-07-01 00:00:00

  • The weights of kidneys in late intrautrine life and childhood.

    abstract::Statistical tables including 50 and 95 percentile ranges are presented of the combined kidney weights compared with body weight, crown-rump length, and gestation age of foetuses and newborn children, and also a table of kidney weights related to post-natal age. The importance of relating kidney weight to more than one...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.13.6.490

    authors: EMERY JL,MITHAL A

    更新日期:1960-11-01 00:00:00

  • Infrequent DNA methylation of miR-9-1 and miR-9-3 in multiple myeloma.

    abstract:AIMS:The miR-9 family microRNAs (miRNAs) are tumour suppressor miRNAs implicated in carcinogenesis. We postulated that miR-9-1, miR-9-2 and miR-9-3 may be inactivated by aberrant promoter methylation in multiple myeloma (MM). METHODS:Methylation of miR-9-1, miR-9-2 and miR-9-3 was studied by methylation-specific PCR (...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2014-202817

    authors: Zhang Q,Wang LQ,Wong KY,Li ZY,Chim CS

    更新日期:2015-07-01 00:00:00

  • Clinical evaluation of the urinary sediment after renal allotransplantation.

    abstract::The detection of lymphoid cells by routine examination of the urine after renal allotransplantation has proved to be a useful early indication of rejection. In a study of 36 rejection episodes, 20 (56%) were associated with a significant number of lymphocytes in the urine. The incidence was much higher when rejection ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.23.2.99

    authors: Papadimitriou M,Chisholm GD,Kulatilake AE,Shackman R

    更新日期:1970-03-01 00:00:00

  • Stromal keratin expression in phyllodes tumours of the breast: a comparison with other spindle cell breast lesions.

    abstract:AIM:To determine the frequency, pattern and distribution of stromal keratin expression in phyllodes tumours if any, which may impact diagnostic approaches. METHODS:The clinicopathological features of 109 phyllodes tumours comprising 70 (64.2%) benign, 30 (27.5%) borderline and nine (8.3%) malignant grades were evaluat...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2011-200377

    authors: Chia Y,Thike AA,Cheok PY,Yong-Zheng Chong L,Man-Kit Tse G,Tan PH

    更新日期:2012-04-01 00:00:00