Combined sputum hypermethylation and eNose analysis for lung cancer diagnosis.

abstract：AIMS:Low-grade myofibroblastic sarcoma (LGMS) represents a rare soft tissue neoplasm with a predilection for the head and neck. Intra-abdominal LGMS are rare with only four unequivocal examples reported so far. Two further cases in females in their 60s and 70s are analysed here. METHODS:Immunohistochemical stains were...

journal_title：Journal of clinical pathology

authors： Agaimy A,Wünsch PH,Schroeder J,Gaumann A,Dietmaier W,Hartmann A,Hofstaedter F,Mentzel T

更新日期：2008-03-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the mismatch repair gene expression and their correlation with NF-kB in patients with oral squamous cell carcinoma (SCC). METHODS:Total RNA was isolated from 28 biopsy samples. A control group was composed of 20 volunteers. Differential expression of hMSH2, hMSH6 and NF-kB ge...

journal_title：Journal of clinical pathology

authors： Fonseca A,Perez M,Veiga G,Prosdócimi F,Nunes F,Bianco B,Fonseca F,Alves B

更新日期：2020-05-01 00:00:00

abstract：:Haematological malignancies are a diverse group of cancers that affect the blood, bone marrow and lymphatic systems. Laboratory diagnosis of haematological malignancies is dependent on combining several technologies, including morphology, immunophenotyping, cytogenetics and molecular genetics correlated clinical detai...

journal_title：Journal of clinical pathology

authors： Snowden JA,O'Connell S,Hawkins J,Dalley C,Jack A,Mannari D,McNamara C,Scott M,Shenton G,Soilleux E,Macbeth F,Guideline Committee.

更新日期：2017-06-01 00:00:00

abstract：:There is currently much speculation over the precise nature of lobular carcinoma in-situ of the breast and its significance. Histochemical study shows that it is rich in sialomucin. This has a characteristic intracellular distribution which distinghishes lobular carcinoma in-situ from cancerization of lobules. The sam...

journal_title：Journal of clinical pathology

authors： Gad A,Azzopardi JG

更新日期：1975-09-01 00:00:00

abstract：:Plasma fibronectin concentrations up to 85 mg/100 ml were found in hyperthyroid patients. There was a significant correlation between free thyroxine index and plasma fibronectin values. Hypothyroid patients had low to normal fibronectin concentrations. Parallel decreases of thyroid hormones and plasma fibronectin conc...

journal_title：Journal of clinical pathology

authors： Graninger W,Pirich K,Derfler K,Waldhäusl W

更新日期：1985-01-01 00:00:00

abstract：:Two aspects of handwashing in hospital were considered. A study was carried out to examine the contamination of bar soap and containers, and the use of antiseptic soaps in reducing the resident flora of the skin. Swabs were collected from soap dishes on six wards and from a bacteriology laboratory on four consecutive ...

journal_title：Journal of clinical pathology

authors： Jarvis JD,Wynne CD,Enwright L,Williams JD

更新日期：1979-07-01 00:00:00

abstract：:Lymphocyte-depleted classical Hodgkin lymphoma (LDCHL) is the rarest entity among the classical Hodgkin lymphoma (CHL) subtypes, accounting for <1% of CHL cases in Western countries. Similarly, primary splenic Hodgkin lymphoma is a rare diagnosis among all cases of lymphomatous involvement of spleen. Representing a co...

journal_title：Journal of clinical pathology

authors： Parekh V,Peker D

更新日期：2015-11-01 00:00:00

abstract：AIMS:Congenital neutropenia (CN) is a rare inherited disease that results in recurrent, life-threatening bacterial infections due to a deficiency of mature neutrophils. They are usually caused by heterozygous ELANE mutations although mutations in other genes like HAX-1, G6PC3 and GFI1 have also been reported. Identifyi...

journal_title：Journal of clinical pathology

authors： Arunachalam AK,Suresh H,Edison ES,Korula A,Aboobacker FN,George B,Shaji RV,Mathews V,Balasubramanian P

更新日期：2020-06-01 00:00:00

abstract：AIMS:To determine important factors influencing recurrence after local excision of duct carcinoma in situ (DCIS) of the breast. MATERIALS AND METHODS:The extent (size) in millimetres, classification (by cytonuclear grade (NHSBSP system), by extent of necrosis, and by the Van Nuys system), and excision margins of 115 c...

journal_title：Journal of clinical pathology

authors： Douglas-Jones AG,Logan J,Morgan JM,Johnson R,Williams R

更新日期：2002-08-01 00:00:00

abstract：AIM:Solid and papillary epithelial neoplasm (SPEN) is an uncommon pancreatic tumour. Very rarely it has also been described outside the pancreas, usually arising from heterotopic pancreatic tissue. This report summarises all the published extrapancreatic SPENs and documents the sixth such case arising from heterotopic ...

journal_title：Journal of clinical pathology

authors： Tornóczky T,Kálmán E,Jáksó P,Méhes G,Pajor L,Kajtár GG,Battyány I,Davidovics S,Sohail M,Krausz T

更新日期：2001-03-01 00:00:00

abstract：:Serum glutamic oxalacetic transaminase (G-OT), glutamic-pyruvic transaminase (G-PT), and isocitric dehydrogenase (ICD) have been estimated in six groups of subjects, namely, normal British adults, normal Nigerian adults, undernourished Nigerian adults and children, Nigerian children with florid protein malnutrition (k...

journal_title：Journal of clinical pathology

authors： BARON DN

更新日期：1960-05-01 00:00:00

abstract：:Two cases of chronic coronary periarteritis associated with chronic periaortitis are described. In one, the chronic periaortitis took the form of perianeurysmal fibrosis around a thoracic atherosclerotic aneurysm; in the other it resembled idiopathic retroperitoneal fibrosis. The findings in the two subjects support t...

journal_title：Journal of clinical pathology

authors： Mitchinson MJ,Wight DG,Arno J,Milstein BB

更新日期：1984-01-01 00:00:00

abstract：:The role of active hepatitis B virus (HBV) infection in chronic HBsAg positive hepatitis with and without hepatitis delta virus (HDV) superinfection was analysed in percutaneous liver biopsy specimens from 50 patients. Each specimen was divided into two--one part for histological evaluation and for the detection of HB...

journal_title：Journal of clinical pathology

authors： Villari D,Raimondo G,Smedile V,Rodinó G,Brancatelli S,Longo G,Squadrito G,Batolo D

更新日期：1989-07-01 00:00:00

abstract：AIMS:To investigate the correlation between centrally assessed human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) results and response to treatment of patients with metastatic breast cancer enrolled in a first-line, phase II, open-label, 3-weekly tra...

journal_title：Journal of clinical pathology

authors： Hofmann M,Stoss O,Gaiser T,Kneitz H,Heinmöller P,Gutjahr T,Kaufmann M,Henkel T,Rüschoff J

更新日期：2008-01-01 00:00:00

abstract：AIM:To develop a simple but reliable polymerase chain reaction (PCR) method to determine the HIV-1 status of patients on formalin fixed, paraffin wax embedded lymph node tissue. METHODS:Fifty lymph node specimens, 20 from HIV-1 seropositive and 30 from HIV-1 seronegative patients, were analysed. Lymph nodes with a var...

journal_title：Journal of clinical pathology

authors： Slavik T,Wolfaardt M,van Zyl H,Simson IW

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND/AIMS:In the natural history of gastric cancer, non-invasive neoplasia (NiN) precedes invasive carcinoma. A histological classification of gastric NiN has recently been proposed by a World Health Organisation international panel of experts. Genetic instability is known to be among the molecular pathways invol...

journal_title：Journal of clinical pathology

authors： Rugge M,Bersani G,Bertorelle R,Pennelli G,Russo VM,Farinati F,Bartolini D,Cassaro M,Alvisi V

更新日期：2005-08-01 00:00:00

abstract：:Transmembrane serine protease 2 is encoded by the TMPRSS2 gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the inactive zymogen form. A fusion gene between the TMPRSS2 gene and ERG (erythroblast-specific-related gene), an oncogenic transcription factor, is the most c...

journal_title：Journal of clinical pathology

authors： Thunders M,Delahunt B

更新日期：2020-12-01 00:00:00

abstract：:Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant hi...

journal_title：Journal of clinical pathology

authors： Salter DM,Krajewski AS,Dewar AE

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Periostin is a secreted adhesion protein, normally expressed in mesenchime-derived cells. Aberrant expression of the periostin gene in epithelial tumours seems to play a role in angiogenesis and metastases. AIMS:To investigate periostin expression in a consecutive series of breast carcinomas and correlate i...

journal_title：Journal of clinical pathology

authors： Puglisi F,Puppin C,Pegolo E,Andreetta C,Pascoletti G,D'Aurizio F,Pandolfi M,Fasola G,Piga A,Damante G,Di Loreto C

更新日期：2008-04-01 00:00:00

abstract：:IgD myeloma is a rare disorder with a very poor prognosis. An unusual case is reported where prolonged remission was obtained. Immunohistochemical staining of the bone marrow trephine biopsy specimen proved invaluable in documenting early relapse. It is suggested that immunohistochemistry should be adopted more widely...

journal_title：Journal of clinical pathology

authors： Kettle P,Morris TC

更新日期：1994-08-01 00:00:00

abstract：:Leucocyte ascorbate (LA) and serum ascorbate (SA) were measured in patients who had sustained an acute cerebrovascular accident. There was a significant fall in LA and Sa within 24 hours of the incident and this persisted for several weeks. The "stress" of the event resulted in a rise in serum cortisol concentration a...

journal_title：Journal of clinical pathology

authors： Hume R,Vallance BD,Muir MM

更新日期：1982-02-01 00:00:00

abstract：AIMS:Because sentinel lymph node (SLN) biopsy for breast cancer has become well established, one of the challenges now is to determine which patients require a completion axillary dissection following a positive SLN biopsy. METHODS:A prospective database of patients who underwent SLN biopsy for invasive breast cancer ...

journal_title：Journal of clinical pathology

authors： Fleming FJ,Kavanagh D,Crotty TB,Quinn CM,McDermott EW,O'Higgins N,Hill AD

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is an important diagnosis. New criteria have been defined for impaired glucose metabolism and, accordingly, there is a need for precise and accurate glucose analysis for the correct classification of patients. However, neither the World Health Organisation nor the National Service Framework...

journal_title：Journal of clinical pathology

authors： Twomey PJ

更新日期：2004-07-01 00:00:00

abstract：AIMS:Traditionally, advanced stage ovarian carcinoma is treated by debulking surgery followed by chemotherapy. However, in some circumstances preoperative chemotherapy may be given before optimal surgical debulking. This study aims to describe the morphological features found in ovarian carcinoma after chemotherapy bec...

journal_title：Journal of clinical pathology

authors： McCluggage WG,Lyness RW,Atkinson RJ,Dobbs SP,Harley I,McClelland HR,Price JH

更新日期：2002-01-01 00:00:00

abstract：:A method is described for the separation and determination of individual bile acids in serum and in intestinal contents, employing thin-layer chromatography and fluorimetry. The mean recovery from intestinal juice was 94% and from serum 82%. Normal values for the individual bile acids of serum and examples of clinical...

journal_title：Journal of clinical pathology

authors： Panveliwalla D,Lewis B,Wootton ID,Tabaqchali S

更新日期：1970-05-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00

abstract：AIM:To investigate whether there is loss of the p27Kip1 protein in developing cervical cancer and whether p27Kip1 immunoreactivity has any relation to the proliferative indicator Ki-67. METHODS:The expression of p27Kip1 and Ki-67 was assessed by immunohistochemistry in serial sections from normal epithelium (13), low ...

journal_title：Journal of clinical pathology

authors： Troncone G,Vetrani A,de Rosa G,Gerbasio D,Palombini L

更新日期：1999-12-01 00:00:00

abstract：:Splenic pathology was analysed in 73 patients with immune thrombocytopenic purpura who underwent splenectomy for bleeding that had been resistant to adrenocorticosteroids. The mean splenic weight was 100 g. The only notable macroscopic feature was the prominence of Malpighian corpuscles in 15 cases. Microscopic examin...

journal_title：Journal of clinical pathology

authors： Hayes MM,Jacobs P,Wood L,Dent DM

更新日期：1985-09-01 00:00:00

abstract：AIMS:To compare prognostic information obtained by image analysis cytometry of paraffin wax embedded soft tissue sarcomas with conventional assessment. METHODS:A CAS 200 image analyser was used to determine DNA content of Feulgen stained cytology preparations and tissue sections and to quantify immunostaining by Ki67 ...

journal_title：Journal of clinical pathology

authors： Michie BA,Black C,Reid RP,Barrett A,Hamblen DL

更新日期：1994-05-01 00:00:00

abstract：AIM:To better understand the spectrum of primary lymphomas in the upper aerodigestive tract, a common site of extranodal lymphoma. MATERIALS AND METHODS:Lymphoma cases diagnosed at an institution in southern Taiwan from 1992 to 2007 were retrospectively studied with pathology and history review, immunohistochemistry, ...

journal_title：Journal of clinical pathology

authors： Chen SW,Chang ST,Lu CL,Hwang WS,Tsao CJ,Huang WT,Chang KY,Chuang SS

更新日期：2010-10-01 00:00:00