Handwashing and antiseptic-containing soaps in hospital.

abstract：:A knowledge-based computer system, designed to assist pathologists in the histological diagnosis of breast disease, is described. This system represents knowledge in the form of "disease profiles" and uses a novel inference model based on the mathematical technique of hypergraphs. Its design overcomes many of the limi...

journal_title：Journal of clinical pathology

authors： Heathfield H,Bose D,Kirkham N

更新日期：1991-06-01 00:00:00

abstract：:The ability of erythrocytes to synthesize porphyrins from delta-aminolaevulic acid was compared in healthy people, patients with true iron-deficiency anaemia, and anaemic patients with rheumatoid arthritis. Porphyrin synthesis was found to be impaired in true iron deficiency but not in rheumatoid arthritis cases showi...

journal_title：Journal of clinical pathology

authors： Gutniak O,Kopéc M,Nieczaj J

更新日期：1971-05-01 00:00:00

abstract：:Bilateral adrenalectomy produces a reduction in the alkaline phosphatase concentration in rat intestine, which is not prevented by the administration of saline, but is prevented by the administration of cortisone. The administration of A.C.T.H. to normal rats leads to a rise in intestinal alkaline phosphatase levels a...

journal_title：Journal of clinical pathology

authors： Watson WC,Murray ES,Gardner MD

更新日期：1967-03-01 00:00:00

abstract：:Mesothelial lesions pose considerable diagnostic challenges not only because benign tumours, reactive proliferations and malignant mesothelioma can mimic one another, but also because the morphological patterns displayed by malignant mesothelioma can simulate a variety of epithelial and non-epithelial malignancies. Im...

journal_title：Journal of clinical pathology

authors： Butnor KJ

更新日期：2006-06-01 00:00:00

abstract：:A case of bacterial endocarditis was caused by Cardiobacterium hominis in a 41-year-old man with mitral and aortic incompetence due to a previous episode of rheumatic fever. The main distinguishing characteristics of C. hominis are described, and the incidence of endocarditis is reviewed. After six weeks of treatment ...

journal_title：Journal of clinical pathology

authors： Jobanputra RS,Moysey J

更新日期：1977-11-01 00:00:00

abstract：:The number of granulocyte/macrophage colonies grown in vitro from bone marrow cells obtained from 90 rib segments and 30 ;normal' bone marrow aspirates was found to be highly variable. Considerable variation was also noted in the relationship between colony number and the number of cells cultured in both groups. The a...

journal_title：Journal of clinical pathology

authors： Morris TC,McNeill TA,Bridges JM

更新日期：1974-10-01 00:00:00

abstract：AIMS:In the gastric antrum and body, foveolar hyperplasia is a feature of reactive gastritis resulting from--for example, duodenogastric bile reflux and the use of non-steroidal anti-inflammatory drugs (NSAIDs). The aim of this study was to examine the occurrence and clinical relevance of gastric cardiac foveolar hyper...

journal_title：Journal of clinical pathology

authors： Voutilainen M,Juhola M,Färkkilä M,Sipponen P

更新日期：2002-05-01 00:00:00

abstract：AIMS:To establish a three dimensional reconstruction of an invasive breast carcinoma using basic laboratory equipment to evaluate and characterise the spatial arrangement of the parenchymal cells of the breast. METHODS:One hundred and twenty eight sequential 4 microm sections (20 microm apart) of the tumour were stain...

journal_title：Journal of clinical pathology

authors： Kurien T,Boyce RW,Paish EC,Ronan J,Maddison J,Rakha EA,Green AR,Ellis IO

更新日期：2005-09-01 00:00:00

abstract：:Factor VIII procoagulant activity (VIII:C), factor VIII related antigen (VIIIR:AG), and the von Willebrand factor (VIII:WF) were measured in 19 patients with liver disease (8 cases of alcoholic cirrhosis and 11 with acute viral hepatitis). In both groups of patients the levels of VIII:C, VIIIR:AG, and VIIIR:WF were ab...

journal_title：Journal of clinical pathology

authors： Maisonneuve P,Sultan Y

更新日期：1977-03-01 00:00:00

abstract：:A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in gamma globulin was also noted from the...

journal_title：Journal of clinical pathology

authors： RAWSTRON JR,FARTHING CP

更新日期：1962-03-01 00:00:00

abstract：:Metabolic balance studies for iron have been carried out on 24 apparently healthy elderly people (11 men and 13 women) aged 69.7 to 85.5 years living in their own homes and eating self selected diets. Several biochemical and haematological indices of iron state were also measured. The mean daily iron intake was 176 mu...

journal_title：Journal of clinical pathology

authors： Bunker VW,Lawson MS,Clayton BE

更新日期：1984-12-01 00:00:00

abstract：:The Kallestad Corporation recently suggested that their new buffer system for the nephelometric detection of rheumatoid factor conferred advantages over existing systems. Two rate nephelometric procedures, the Kallestad QM-300 and the Beckman ICS-II (RF), were therefore compared. Sera (n = 157) were selected on the ba...

journal_title：Journal of clinical pathology

authors： Collins RJ,Neil JC,Wilson RJ

更新日期：1990-03-01 00:00:00

abstract：:Late-stage ovarian carcinoma is almost universally fatal. BRCA mutations are associated with an improved outcome and enhanced sensitivity to platinum chemotherapy, yet recurrence and platinum resistance remain a major problem and highly effective regimens following platinum failure do not yet exist. Here we report a r...

journal_title：Journal of clinical pathology

authors： Osher DJ,Kushner YB,Arseneau J,Foulkes WD

更新日期：2011-10-01 00:00:00

abstract：:A method for accurately counting platelets is described using the Coulter counter model B fitted with a standard 100mu aperture tube. This enables the counter to be used for red and white cell as well as platelet counts using the same aperture tube. The method uses standard equipment except for a small inexpensive ele...

journal_title：Journal of clinical pathology

authors： Davis RE,Green RE

更新日期：1967-09-01 00:00:00

abstract：:Several studies have recently documented the presence of persistently abnormal liver function tests in asymptomatic haemophiliacs. While the aetiology is unknown it is possible that repeated exposure to agents transmitted in blood products may be important. This study has attempted to determine the prevalence of viral...

journal_title：Journal of clinical pathology

authors： McVerry BA,Ross MG,Knowles WA,Voke J

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Cytokeratin immunohistochemistry (IHC) reveals a higher rate of occult lymph node metastases among lobular carcinomas than among ductal breast cancers. IHC is widely used but is seldom recommended for the evaluation of sentinel lymph nodes in breast cancer patients. OBJECTIVE:To assess the value of cytokera...

journal_title：Journal of clinical pathology

authors： Cserni G,Bianchi S,Vezzosi V,Peterse H,Sapino A,Arisio R,Reiner-Concin A,Regitnig P,Bellocq JP,Marin C,Bori R,Penuela JM,Iturriagagoitia AC

更新日期：2006-05-01 00:00:00

abstract：AIM:To investigate the natural history of patients with non-alcoholic steatohepatitis by means of a prospective histological study. METHODS:One thousand five hundred and seventy one patients underwent liver biopsy at the Western Infirmary in Glasgow during the 10 year period 1985 to 1994. All biopsies were reported by...

journal_title：Journal of clinical pathology

authors： Evans CD,Oien KA,MacSween RN,Mills PR

更新日期：2002-09-01 00:00:00

abstract：AIMS:To determine how epithelial and stromal thymidine phosphorylase expression affects angiogenesis, rapid tumour growth, and decreased apoptotic activity in cervical cancer at varying stages of progression. METHODS:Epithelial and stromal thymidine phosphorylase expression, the microvessel count (reflected by factor ...

journal_title：Journal of clinical pathology

authors： Fujiwaki R,Hata K,Iida K,Maede Y,Koike M,Miyazaki K

更新日期：1999-08-01 00:00:00

abstract：:The indirect immunofluorescence technique was used to study the expression of the blood group A and H antigens in fresh-frozen and formalin-fixed paraffin-embedded sections of the bladder mucosa of 21 patients with non-neoplastic diseases of the bladder. Reliable assessment of these antigens could only be made using c...

journal_title：Journal of clinical pathology

authors： Thorpe SJ,Abel P,Slavin G,Feizi T

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Hepatic fibrosis is one of the main consequences of liver disease. Both fibrosis and steatosis may be seen in some patients with chronic hepatitis C and alcoholic liver disease (ALD). AIMS:To quantitate fibrosis and steatosis by stereological and morphometric techniques in patients with chronic hepatitis C ...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,Al Mardini H,Awad S,Ukabam S,Makadisi S,Record CO

更新日期：2001-06-01 00:00:00

abstract：AIMS:To use the polymerase chain reaction to detect monoclonality at the immunoglobulin heavy chain gene locus in cells derived from lymph node aspirates. METHODS:A nested two-stage polymerase chain reaction (PCR) for the VDJ region of the immunoglobulin heavy chain gene was used to detect monoclonality. The total num...

journal_title：Journal of clinical pathology

authors： Wan JH,Sykes PJ,Orell SR,Morley AA

更新日期：1992-05-01 00:00:00

abstract：:In an investigation of the in vitro phagocytic and microbicidal function of granulocytes collected by filtration leucapheresis (FL) from 18 donors and by discontinuous flow centrifugation leucapheresis (DFC) from six donors, comparison was made with the function of granulocytes obtained from the same donors by venepun...

journal_title：Journal of clinical pathology

authors： Martin S,Ghoneim AT,Robinson EA,Child JA

更新日期：1983-05-01 00:00:00

abstract：AIMS:To establish the current sensitivity of two commercial kits for culture confirmation of Neisseria gonorrhoeae strains circulating in the UK. METHODS:A total of 544 strains were studied (199 gonococci from male patients attending hospitals in the county of Avon, 204 unselected N gonorrhoeae isolates from male pati...

journal_title：Journal of clinical pathology

authors： Turner A,Gough KR,Jephcott AE

更新日期：1995-10-01 00:00:00

abstract：:Blood cultures drawn from a patient with clinically diagnosed invasive meningococcal disease, who had been previously administered benzylpenicillin, had beta-lactamases added to increase the probability of recovery of the causative organism. The blood cultures subsequently yielded Neisseria meningitidis but direct sus...

journal_title：Journal of clinical pathology

authors： Weightman NC

更新日期：2001-11-01 00:00:00

abstract：:Urine specimens were collected from 26 normal subjects, 10 patients with proven primary hyperparathyroidism, and eight patients with hypercalcaemia due to other causes. After overnight urine concentration, an oral water load was given to induce a diuresis and provide urine specimens with a relatively wide range of cre...

journal_title：Journal of clinical pathology

authors： Wills MR

更新日期：1969-05-01 00:00:00

abstract：:Four strains of Corynebacterium diphtheriae were sent to UK participants in the UK National External Microbiological Quality Assessment Scheme, who were asked to examine the strains for toxin production by in vitro methods. Laboratories achieved 162/176 (92%) and 160/175 (91%) correct results with two rapid toxin prod...

journal_title：Journal of clinical pathology

authors： Snell JJ,Demello JV,Gardner PS,Kwantes W,Brooks R

更新日期：1984-07-01 00:00:00

abstract：:The T(4)-free thyroxine index was used as the thyroid function test of first choice in a district general hospital for one year. Ninety-two patients were assessed both initially and at follow up by a single physician. The index agreed with clinical assessment in 69 out of 74 patients in whom diagnosis was unequivocal....

journal_title：Journal of clinical pathology

authors： Howorth PJ,Ward RL

更新日期：1972-03-01 00:00:00

abstract：AIMS:The purpose of this study was to compare the DNA-methylation signature in classic chronic Philadelphia negative myeloproliferative neoplasms (MPN), polycythaemia vera (PV) and essential thrombocythaemia (ET), in order to obtain a global insight into DNA-methylation changes associated with these malignancies. METH...

journal_title：Journal of clinical pathology

authors： Barrio S,Gallardo M,Albizua E,Jimenez A,Rapado I,Ayala R,Gilsanz F,Martin-Subero JI,Martinez-Lopez J

更新日期：2011-11-01 00:00:00

abstract：AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...

journal_title：Journal of clinical pathology

authors： González MV,Pello MF,López-Larrea C,Suárez C,Menéndez MJ,Coto E

更新日期：1997-06-01 00:00:00

abstract：:Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant hi...

journal_title：Journal of clinical pathology

authors： Salter DM,Krajewski AS,Dewar AE

更新日期：1986-01-01 00:00:00