Immunophenotype analysis of malignant histiocytosis of the intestine.

Abstract:

:Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant histiocytosis of the intestine and the case of histiocytic lymphoma expressed the epithelial membrane antigen. Cryostat sections in four cases of malignant histiocytosis of the intestine showed that most tumour cells reacted with anti-T cell monoclonal antibodies. Only a minority expressed a typical monocyte macrophage phenotype.

journal_name

J Clin Pathol

authors

Salter DM,Krajewski AS,Dewar AE

doi

10.1136/jcp.39.1.8

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

8-15

issue

1

eissn

0021-9746

issn

1472-4146

journal_volume

39

pub_type

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