Neisseria gonorrhoeae: a versatile pathogen.

abstract：:Isolates of Bacillus cereus from 118 cases, and two maternity unit outbreaks, of non-gastrointestinal infection were grouped on the basis of their estimated probable involvement in the infections from which they were isolated: (i) high probability--48 strains; (ii) intermediate--16 strains; (iii) low--7 strains; (iv) ...

journal_title：Journal of clinical pathology

authors： Turnbull PC,Kramer JM

更新日期：1983-10-01 00:00:00

abstract：:A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

journal_title：Journal of clinical pathology

authors： Green NE

更新日期：1979-06-01 00:00:00

abstract：:One hundred prostates from 20 to 40 year old men obtained at necropsy were completely sectioned and studied microscopically. Atypical hyperplasia was found in 10 (20%) of 20-29 year old men and in 12 (24%) of 30-40 year old men. The prostates with atypical hyperplasia had similar weights as those without, and the atyp...

journal_title：Journal of clinical pathology

authors： Brawn PN,Speights VO,Contin JU,Bayardo RJ,Kuhl DL

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:The prognosis of adenoid cystic carcinoma (ACC), a malignant salivary gland tumour, depends on clinicopathological parameters. To decipher the biological behaviour of ACC, and to identify patients at risk of developing metastases, additional markers are needed. METHODS:Expression of the cell cycle proteins ...

journal_title：Journal of clinical pathology

authors： Vékony H,Raaphorst FM,Otte AP,van Lohuizen M,Leemans CR,van der Waal I,Bloemena E

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Although Hashimoto thyroiditis (HT) is a predisposing factor for B-lineage thyroid lymphoma, clonal B-cell populations in HT are rare. AIM:To investigate whether there is a clonal relationship between HT and primary thyroid lymphoma. METHODS:Clonalilty and sequence similarity was determined by PCR followed...

journal_title：Journal of clinical pathology

authors： Moshynska OV,Saxena A

更新日期：2008-04-01 00:00:00

abstract：:Tuberous sclerosis is a rare disease with classic primary or secondary changes affecting mainly the cerebrum, skin, kidneys, and heart. Such lesions are generally hamartomatous and thus display malignant features only in rare cases. This paper describes four cases of tuberous sclerosis which were unique in their assoc...

journal_title：Journal of clinical pathology

authors： Ilgren EB,Westmoreland D

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:HER2/neu (HER2) is a significant prognostic marker for breast carcinomas. Recently, new guidelines defining HER2 genetic heterogeneity (GH) were published by the College of American Pathologists. AIMS:To determine the prevalence of HER2 GH as defined in primary invasive breast carcinoma, to determine its re...

journal_title：Journal of clinical pathology

authors： Shafi H,Astvatsaturyan K,Chung F,Mirocha J,Schmidt M,Bose S

更新日期：2013-08-01 00:00:00

abstract：:Serum C reactive protein concentrations measured by a laboratory based assay were compared with the semiquantitative results obtained with a visual agglutination method (Well-cotest, CRP kit). Using this agglutination kit, diluting serum 1/10 and 1/20 gave C reactive protein results which could be of more clinical val...

journal_title：Journal of clinical pathology

authors： Richards NP,Elliott TS,Powell RJ,O'Callaghan C,Franklin P

更新日期：1985-04-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：:Twenty five specimens of branchial cyst from the same number of patients have been examined. On staining with haematoxylin and eosin a consistent finding was that the mural lymphoid follicles were always aligned with their mantle zones towards the luminal epithelium. With conventional staining lymphatic sinuses were n...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R

更新日期：1985-07-01 00:00:00

abstract：:A rapid and reproducible electrophoretic method for the separation and quantitation of haemoglobins on cellulose acetate is described. The accuracy of the method and its possible sources of error are discussed. The normal range for haemoglobin A(2) by this method is 1% to 3% of the total haemoglobin concentration. Blo...

journal_title：Journal of clinical pathology

authors： Marengo-Rowe AJ

更新日期：1965-11-01 00:00:00

abstract：:Pathology review of gynaecological cancer specimens is often carried out as part of the working of gynaecological oncology multidisciplinary team meetings. This review describes the author's experience regarding the most common issues identified during this process. Ten subjects are covered; these range from histopath...

journal_title：Journal of clinical pathology

authors： McCluggage WG

更新日期：2012-04-01 00:00:00

abstract：AIMS:Positive direct antiglobulin tests (DATs) are valuable in identifying the aetiology of autoimmune haemolysis and in guiding therapeutic intervention. However, in HIV-positive individuals with background polyclonal gammopathy, a positive DAT in the absence of haemolysis is common. In this setting, IgG quantificatio...

journal_title：Journal of clinical pathology

authors： Chetty T,Bouwer N,Wan YO,Mahlangu J

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:Friend leukaemia integration-1 (FLI-1) antibody is a useful marker for Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET) and vascular tumours. However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT). AIM:To de...

journal_title：Journal of clinical pathology

authors： Mhawech-Fauceglia P,Herrmann FR,Bshara W,Odunsi K,Terracciano L,Sauter G,Cheney RT,Groth J,Penetrante R,Mhawech-Fauceglia P

更新日期：2007-06-01 00:00:00

abstract：AIMS:Immunohistochemical stains have greatly improved the diagnostic accuracy of renal cell carcinoma (RCC) for primary and distant tumours. We evaluate a marker that has recently been incorporated in clinical practice, PAX-8, in primary and metastatic RCCs. METHODS:Two distinct tissue microarrays were used, one consi...

journal_title：Journal of clinical pathology

authors： Barr ML,Jilaveanu LB,Camp RL,Adeniran AJ,Kluger HM,Shuch B

更新日期：2015-01-01 00:00:00

abstract：:Platelet adhesiveness was measured in patients undergoing operation. With the rotating bulb technique adhesiveness increased steadily to the sixth and ninth days following surgery. The glass bead filter technique demonstrated a marked increase in platelet adhesiveness on the day following operation. ...

journal_title：Journal of clinical pathology

authors： Bennett PN

更新日期：1967-09-01 00:00:00

abstract：AIMS:Clot waveform analysis (CWA) has been reported to extend the interpretation of clotting time measurement. The parameters obtained from successive derivatives of the clotting reaction curves reflect the rates of activation of individual coagulation factors, theoretically dissecting the cascade pathway. This study a...

journal_title：Journal of clinical pathology

authors： Wakui M,Fujimori Y,Katagiri H,Nakamura S,Kondo Y,Kuroda Y,Nakagawa T,Shimizu N,Murata M

更新日期：2019-03-01 00:00:00

abstract：:Xanthine oxidase (XO) activity was found to be negligible in sterile human urines (less than 480 units, as presently defined, per litre). Significant XO activity was found in all urines containing more than 10(5) bacteria/ml, except for urines infected with Staphylococcus aureus, in which XO activity ranged from 347 t...

journal_title：Journal of clinical pathology

authors： Giler S,Henig EF,Urca I,Sperling O,de Vries A

更新日期：1978-05-01 00:00:00

abstract：:This article reviews recent information concerning the origin of osteoclasts and the local and systemic regulation of their activity. It appears that much of the environmental responsiveness of osteoclasts is mediated by cells of the osteoblastic lineage, which exert a major influence on the localisation, induction, s...

journal_title：Journal of clinical pathology

authors： Chambers TJ

更新日期：1985-03-01 00:00:00

abstract：:As part of a wider survey of infections and defence mechanisms, concentrations of serum immunoglobulins IgG, IgA, and IgM were measured regularly by single radial immunodiffusion in a group of children receiving treatment for acute lymphoblastic leukaemia while in their first remission. IgM concentrations were often m...

journal_title：Journal of clinical pathology

authors： Reid MM,Craft AW,Cox JR

更新日期：1981-05-01 00:00:00

abstract：:Sera from 5171 inpatients have been tested for HBAg and HBAb during the 18-month period ending in December 1972. The incidence of HBAg (0.116%) was similar to that in blood donors (0.119%) in the same area, being tested for the first time by the same technique. By contrast the incidence of HBAb in patients (0.271%) wa...

journal_title：Journal of clinical pathology

authors： Payne RW,Barr A,Wallace J

更新日期：1974-02-01 00:00:00

abstract：:Severe osteomalacia (confirmed by the examination of thin undecalcified bone biopsy sections) associated with hypophosphataemia developed in a 60 year old woman. A skeletal x-ray survey showed a lytic lesion in the right proximal femur, and this was curetted, showing a vascular tumour. The patient's symptoms improved ...

journal_title：Journal of clinical pathology

authors： McClure J,Smith PS

更新日期：1987-04-01 00:00:00

abstract：:A case of cirrhosis of the liver, associated with false-positive serological tests for syphilis and an antibody active against stored red cells, is presented. Methods used in the identification of the ;stored red cell' antibody are described. ...

journal_title：Journal of clinical pathology

authors： EASTON JA,PRIEST CJ,GILES CM

更新日期：1965-07-01 00:00:00

abstract：AIMS:To validate a method of assessment of low hepatic iron concentration based on a biochemical colorimetric assay plus histological scoring. METHODS:The within-day and day to day precision of the iron colorimetric assay was determined on frozen rat liver. The coefficient of variation (CV) of iron measurement in two ...

journal_title：Journal of clinical pathology

authors： Imbert-Bismut F,Charlotte F,Turlin B,Khalil L,Piton A,Brissot P,Le Charpentier Y,Delattre J,Opolon P,Deugnier Y,Poynard T

更新日期：1999-06-01 00:00:00

abstract：AIMS:The Royal College of Pathologists recommend that a median of at least 12 lymph nodes should be harvested during pathological staging of colorectal cancer. It is not always easy to harvest the required number, especially in patients with rectal cancer receiving neoadjuvant therapy. Lymph node revealing solutions, f...

journal_title：Journal of clinical pathology

authors： Horne J,Carr NJ,Bateman AC,Kandala N 2nd,Adams J,Silva S,Ryder I

更新日期：2016-06-01 00:00:00

abstract：:The costs of a clinical chemistry laboratory in a district general hospital were studied. The system used has certain advantages over the conventional Cooper Lybrand method. The time taken by technicians to perform tests was more variable than expected and the cost of sample collection was higher than process-cost for...

journal_title：Journal of clinical pathology

authors： Stilwell JA

更新日期：1981-06-01 00:00:00

abstract：:Specimens of muscle were obtained from non-suppurating lesions of nine patients with tropical myositis. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure. Perimysial cells were also degenerate. Sections from two out of nine patients revealed intracellular vesicles,...

journal_title：Journal of clinical pathology

authors： Taylor JF,Fluck D,Fluck D

更新日期：1976-12-01 00:00:00

abstract：:A post-mortem examination, in the case of a 34-year-old man dying suddenly from head injuries sustained in a road accident, showed early cirrhosis of the liver and associated splenomegaly 17 years after an attack of infective hepatitis. The histology of the thymus showed abnormal changes in the medulla, consisting of ...

journal_title：Journal of clinical pathology

authors： CORRIDAN M

更新日期：1963-09-01 00:00:00

abstract：:Factor VIII-containing materials were administered to four severely affected haemophiliacs twice weekly in doses calculated to raise the factor VIII level to either 15% or 30% of average normal. The pooled results from those patients with statistically similar baseline bleeding frequencies showed a significant reducti...

journal_title：Journal of clinical pathology

authors： Aronstam A,Kirk PJ,McHardy J,Culver-James JW,McLellan DS,Turk P,Rainsford SG,Slattery M

更新日期：1977-01-01 00:00:00

abstract：AIMS:To develop a rapid, sensitive, and safe method for the analysis of von Willebrand factor (vWf) multimers in plasma or platelet lysates. METHOD:Analysis of vWf multimers was carried out by sodium dodecyl sulphate-agarose discontinuous gel electrophoresis followed by protein transfer to nitrocellulose membranes by ...

journal_title：Journal of clinical pathology

authors： Cumming AM,Wensley RT

更新日期：1993-05-01 00:00:00