Tuberous sclerosis: unusual associations in four cases.

abstract：:Autoinfective strongyloidiasis is often fatal in immunosuppressed patients or in immunocomprised hosts. An interesting case of Strongyloides stercolaris hyperinfection was seen in an immunocompetent patient. This report describes a case of fatal strogyloidiasis in a 79 year old man, who had suffered gastrointestinal d...

journal_title：Journal of clinical pathology

authors： Mayayo E,Gomez-Aracil V,Azua-Blanco J,Azua-Romeo J,Capilla J,Mayayo R

更新日期：2005-04-01 00:00:00

abstract：:In order to determine the cellular distribution of androgen receptors (AR) in normal liver and to examine whether phenotypic changes occur in a variety of non-neoplastic liver diseases, cryostat sections of explanted livers removed from 52 consecutive patients undergoing orthotopic transplantation were immunostained u...

journal_title：Journal of clinical pathology

authors： Hinchliffe SA,Woods S,Gray S,Burt AD

更新日期：1996-05-01 00:00:00

abstract：:The biochemical assay for the oestrogen receptor has shown the clinical value of knowing the concentration of the receptor within tissue. The immunohistochemical assay is rapidly taking over from the biochemical assay. Therefore, it is vital to have an equivalent scoring system that will have the same predictive value...

journal_title：Journal of clinical pathology

authors： Leake R,Barnes D,Pinder S,Ellis I,Anderson L,Anderson T,Adamson R,Rhodes T,Miller K,Walker R

更新日期：2000-08-01 00:00:00

abstract：:A polyclonal antiserum, produced in sheep and reactive against purified human leucocyte elastase, has been applied to paraffin sections from a range of human tissues by means of the indirect immunoperoxidase method. Striking and consistent results have been obtained. Normal or inflammatory granulocytes were intensely ...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R,Burnett D

更新日期：1984-10-01 00:00:00

abstract：AIMS:To determine the causes of death in patients with osteogenesis imperfecta, excluding infants with the perinatal lethal form (type II). METHODS:Seventy nine patients with known osteogenesis imperfecta were identified, 37 of whom had been seen clinically in life. Causes of death were identified from death certifica...

journal_title：Journal of clinical pathology

authors： McAllion SJ,Paterson CR

更新日期：1996-08-01 00:00:00

abstract：:The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastrit...

journal_title：Journal of clinical pathology

authors： Stolte M,Eidt S

更新日期：1989-12-01 00:00:00

abstract：:Human astrovirus infection often causes outbreaks of self limiting diarrhoea, but may also infect patients who are immunodeficient or immunocompromised. Although there are previous publications relating to various aspects of astroviruses, there is a minimal amount of literature on the histopathological features of gas...

journal_title：Journal of clinical pathology

authors： Sebire NJ,Malone M,Shah N,Anderson G,Gaspar HB,Cubitt WD

更新日期：2004-09-01 00:00:00

abstract：:This review surveys the staging systems used for the classification of colorectal carcinomas, including the TNM system, and focuses on the assessment of the nodal stage of the disease. It reviews the quantitative requirements for a regional metastatic work up, and some qualitative features of lymph nodes that may help...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：2003-05-01 00:00:00

abstract：:Candida spp are the fourth most common group of nosocomial pathogens isolated from patients on medical, surgical, and intensive care wards. Polymicrobial candidaemia has rarely been described. The diagnosis of candidaemia from peripheral blood smears has not been widely reported. This report describes the case of a yo...

journal_title：Journal of clinical pathology

authors： Yera H,Poulain D,Lefebvre A,Camus D,Sendid B

更新日期：2004-02-01 00:00:00

abstract：:Serum lysozyme levels were determined by a turbidometric method using egg white lysozyme as standard in 100 patients with Crohn's disease, 86 with ulcerative colitis, 31 with coeliac disease, and in 38 normal control subjects. Though the levels in Crohn's disease were significantly higher than those in ulcerative coli...

journal_title：Journal of clinical pathology

authors： Mallas E,Terry JM,Asquith P,Cooke WT

更新日期：1976-07-01 00:00:00

abstract：AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...

journal_title：Journal of clinical pathology

authors： González MV,Pello MF,López-Larrea C,Suárez C,Menéndez MJ,Coto E

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:EpCAM is an adhesion molecule of the basolateral membranes in a variety of epithelial cells. Over-expression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. AIMS:To assess the prognostic value of EpCAM in urothelial ...

journal_title：Journal of clinical pathology

authors： Brunner A,Prelog M,Verdorfer I,Tzankov A,Mikuz G,Ensinger C

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Fibrinogen plays a crucial role in the pathophysiology of tumour cell growth, invasion and metastasis. The aim of this study was to evaluate the prognostic significance of pretreatment plasma fibrinogen levels in patients with diffuse large B cell lymphoma (DLBCL) METHODS: Data from 372 patients with DLBCL, ...

journal_title：Journal of clinical pathology

authors： Troppan KT,Melchardt T,Wenzl K,Schlick K,Deutsch A,Bullock MD,Reitz D,Beham-Schmid C,Weiss L,Neureiter D,Tränkenschuh W,Greil R,Neumeister P,Egle A,Pichler M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Although in vitro breast cancer models have demonstrated a role for protein kinase C (PKC) alpha and delta isoforms in endocrine insensitivity and resistance respectively, there is currently little clinical evidence to support these observations. AIMS:To define the pattern of PKC alpha and delta expression ...

journal_title：Journal of clinical pathology

authors： Assender JW,Gee JM,Lewis I,Ellis IO,Robertson JF,Nicholson RI

更新日期：2007-11-01 00:00:00

abstract：:Targeted next-generation sequencing using the 50-gene Ion AmpliSeq Cancer Hotspot Panel v2 identified two significant point mutations in endometrial stromal sarcomas (ESS). Case 1 is a uterine mass from a quadragenarian woman with a karyotype lacking any known ESS rearrangements but demonstrated to have a CTNNB1-activ...

journal_title：Journal of clinical pathology

authors： Patel SB,McCormack C,Hodge JC

更新日期：2020-12-01 00:00:00

abstract：AIMS:To determine the possible histogenesis of the intracranial variant of olfactory neuroblastoma. METHODS:Four specimens from three cases of intracranial olfactory neuroblastoma were studied by light microscopy and immuno-histochemistry, and electron microscopy in two cases. RESULTS:Light microscopical examination ...

journal_title：Journal of clinical pathology

authors： Banerjee AK,Sharma BS,Vashista RK,Kak VK

更新日期：1992-04-01 00:00:00

abstract：:The haematological features of 118 cases of primary myelodysplastic syndromes (PMDS) were reviewed to see how these could be related and classified according to the recent FAB proposals. A majority of the cases were elderly who presented with a macrocytic or normocytic anaemia and reticulocytopenia. Cases of acquired ...

journal_title：Journal of clinical pathology

authors： Juneja SK,Imbert M,Jouault H,Scoazec JY,Sigaux F,Sultan C

更新日期：1983-10-01 00:00:00

abstract：AIMS:To investigate proliferative activity in leukaemic and lymphomatous bone marrow infiltrates and to assess the feasibility of transport of specimens among institutions. METHODS:Proliferative activity in bone marrow trephine cryosections from 99 patients with non-Hodgkin's lymphoma (NHL), 23 patients with acute mye...

journal_title：Journal of clinical pathology

authors： White DM,Smith AG,Smith JL

更新日期：1994-03-01 00:00:00

abstract：:The Fisher Hem-Alyzer is a multitest sequential discrete analyser with automatic printout of digitized results on paper tape. The instrument is well designed, soundly constructed, and reliable in routine use. Cross contamination from the sampler probe or between the cuvettes is minimal. Accuracy and precision are both...

journal_title：Journal of clinical pathology

authors： Lappin TR,Lamont A,Nelson MG

更新日期：1970-02-01 00:00:00

abstract：AIMS:To evaluate the prevalence of pseudoangiomatous hyperplasia of mammary stroma in gynaecomastia and its immunohistochemical profile in this setting. METHODS:Eighty eight cases of gynaecomastia recovered from the files of the department of pathology, Botucatu School of Medicine from 1976 to 1996 were studied. In th...

journal_title：Journal of clinical pathology

authors： Milanezi MF,Saggioro FP,Zanati SG,Bazan R,Schmitt FC

更新日期：1998-03-01 00:00:00

abstract：:Prostaglandin E(2) (PGE(2)) was infused intravenously to eight women for the termination of pregnancy and tests of platelet function: coagulation and fibrinolysis were studied before and during the infusion.Platelet adhesiveness, as measured by a cellophane membrane test-cell system, was significantly diminished by PG...

journal_title：Journal of clinical pathology

authors： Howie PW,Calder AA,Forbes CD,Prentice CR

更新日期：1973-05-01 00:00:00

abstract：:Rocket-line immunoelectrophoresis (R-LIE) with antigen containing intermediate gel, and co-agglutination utilising protein A-containing staphylococci coated with specific antibodies, were adapted for serotyping the prototypes of group B meningococci. Both were found to have the same specificity as agar gel double diff...

journal_title：Journal of clinical pathology

authors： Danielsson D,Olcén P

更新日期：1979-02-01 00:00:00

abstract：:A method is described of measuring the response of human lymphocytes to phytohaemagglutinin stimulation using iododeoxyuridine labelled with the gamma-emitting isotope (125)I. The results indicate useful clinical applications. ...

journal_title：Journal of clinical pathology

authors： Craig AW,Garrett JV,Jackson SM

更新日期：1969-09-01 00:00:00

abstract：:Colonising Campylobacter pyloridis were identified histologically in gastric biopsy specimens from 89% of 83 patients with non-ulcer dyspepsia and chronic gastritis, but not in 58 dyspeptic patients with normal mucosa. The presence and population density of organisms was associated with the presence of intraepithelial...

journal_title：Journal of clinical pathology

authors： Wyatt JI,Rathbone BJ,Heatley RV

更新日期：1986-08-01 00:00:00

abstract：:Using a radioimmunoassay technique serum alpha-fetoprotein could be detected in healthy adults in concentrations of less than 20 microgram/l. Of patients with acute, viral hepatitis 43% exhibited a transient rise of serum alpha-fetoprotein, the peak occurring eight to nine days after the maximum recorded serum asparta...

journal_title：Journal of clinical pathology

authors： Eleftheriou N,Heathcote J,Thomas HC,Sherlock S

更新日期：1977-08-01 00:00:00

abstract：:A case of cryptococcal meningo-encephalitis is described. Treatment with the fungicidal agent amphotericin B resulted in temporary improvement, but the patient relapsed and died 17 months after diagnosis. The pathology and treatment of the disease are discussed. ...

journal_title：Journal of clinical pathology

authors： RIPPEY JJ,ROPER WA,JEANES AL,BRIGHT MV

更新日期：1965-05-01 00:00:00

abstract：:Fluorigenic substrates prepared from 4-methylumbelliferone provide a simple, convenient method for detecting and assaying group-specific hydrolase activity in small quantities of whole mycobacteria. Physico-chemical properties of the enzymes such as pH dependence and heat stability may also be studied. A technique is ...

journal_title：Journal of clinical pathology

authors： Grange JM

更新日期：1978-04-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) to measure free serum IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis was developed. Seven strains of P aeruginosa cells, treated with glutaraldehyde and representing the most commonly isolated serotypes in our cystic fibrosis unit, were used. The ...

journal_title：Journal of clinical pathology

authors： Brett MM,Ghoneim AT,Littlewood JM,Losowsky MS

更新日期：1986-10-01 00:00:00

abstract：:An unusually severe hypersensitivity reaction to carbamazepine is described, in which the patient presented with lymphadenopathy, hepatosplenomegaly, bone marrow suppression, immunosuppression and other features strongly suggestive of a lymphoma. ...

journal_title：Journal of clinical pathology

authors： Yates P,Stockdill G,McIntyre M

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:In experimental glomerulonephritis, inhibition of cyclooxygenase 2 (COX-2) enhances the renocortical expression of pathogenic alpha(v) integrins. AIMS:To study whether this effect is mediated by prostaglandin E(2) (PGE(2)) acting through its EP(3) receptor in cultured rat mesangial cells (MCs). METHODS:MCs...

journal_title：Journal of clinical pathology

authors： Waldner C,Schrör K,Heering P

更新日期：2004-05-01 00:00:00