Pathology of astrovirus associated diarrhoea in a paediatric bone marrow transplant recipient.

abstract：AIMS:To investigate the morphological and histopathological associations between an individual pit seen on stereomicroscopy or magnifying colonoscopy and an individual crypt seen in histological sections; and to examine these associations in colorectal tumours. METHODS:Fourteen thousand and twenty three cases were exa...

journal_title：Journal of clinical pathology

authors： Kudo S,Hirota S,Nakajima T,Hosobe S,Kusaka H,Kobayashi T,Himori M,Yagyuu A

更新日期：1994-10-01 00:00:00

abstract：:Human papillomavirus antigen was found in 39 (16%) of 253 colposcopic biopsies from a group of women at high risk for cervical cancer who had been examined in the early 1970s. Immunohistochemical evidence of papillomavirus infection was found in 20 (30%) of 67 cervical intraepithelial neoplasia lesions infected with w...

journal_title：Journal of clinical pathology

authors： Singer A,Wilters J,Walker P,Jenkins D,Slavin G,Cowdell H,To A,Husain O

更新日期：1985-08-01 00:00:00

abstract：:Small cell neuroendocrine carcinoma of the breast is a rare tumour with less than 30 cases reported in the literature. The clinicopathological findings of three cases of primary neuroendocrine carcinoma of the breast and a review of the pertinent literature are presented. The morphological and immunohistochemical patt...

journal_title：Journal of clinical pathology

authors： Adegbola T,Connolly CE,Mortimer G

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The terminology applied to vascular anomalies has been variable in previously published literature making interpretation suboptimal. The International Society for the Study of Vascular Anomalies (ISSVA) has proposed a revised classification based on clinical features and histopathological findings. This clas...

journal_title：Journal of clinical pathology

authors： Al-Adnani M,Williams S,Rampling D,Ashworth M,Malone M,Sebire NJ

更新日期：2006-12-01 00:00:00

abstract：AIMS:To describe and evaluate two apparently unique cases of inverted hyperplastic (metaplastic) polyposis of the colon. METHODS:The cases were analysed by standard histopathological, histochemical, and immunohistochemical techniques and the findings compared with those of regular hyperplastic polyps of the colorectum...

journal_title：Journal of clinical pathology

authors： Shepherd NA

更新日期：1993-01-01 00:00:00

abstract：AIMS:To assess the prevalence of gastric giardiasis in patients undergoing upper gastrointestinal endoscopy, and to define the clinicopathological correlates of gastric Giardia lamblia infection. METHODS:Consecutive gastric biopsy specimens (n = 15,023) from 11,085 patients, taken at Feltre City Hospital (north easter...

journal_title：Journal of clinical pathology

authors： Doglioni C,De Boni M,Cielo R,Laurino L,Pelosio P,Braidotti P,Viale G

更新日期：1992-11-01 00:00:00

abstract：:Preoperative (neoadjuvant) chemoradiation therapy/treatment (NCRT) is emerging as an important treatment modality in borderline resectable pancreatic ductal adenocarcinoma (PDAC). The constellation of histopathological changes secondary to chemoradiation is diverse and has been well documented, particularly in other g...

journal_title：Journal of clinical pathology

authors： Kalimuthu SN,Serra S,Dhani N,Chetty R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Many patients with advanced cancer are malnourished. Anorexia is common, as is the use of chemotherapy, which may cause nausea and poor appetite. Ten per cent of these patients experience haemorrhagic events. AIM:Since vitamin K deficiency (VKD) causes bleeding, to establish the prevalence of VKD in patient...

journal_title：Journal of clinical pathology

authors： Harrington DJ,Western H,Seton-Jones C,Rangarajan S,Beynon T,Shearer MJ

更新日期：2008-04-01 00:00:00

abstract：:In an era when immunohistochemistry (IHC) is increasingly depended on for histological subtyping, and IHC-determined biomarker informing rapid treatment choices is on the horizon; reproducible, quantifiable techniques are required. This study aimed to compare automated IHC scoring to quantify 6 DNA damage response pro...

journal_title：Journal of clinical pathology

authors： Gentles L,Howarth R,Lee WJ,Sharma-Saha S,Ralte A,Curtin N,Drew Y,O'Donnell RL

更新日期：2020-11-19 00:00:00

abstract：:The development and evaluation of a new selective medium for Streptococcus pneumoniae is described. It is shown that the new medium (crystal violet-nalidixic acid-gentamicin agar:CVNG) is highly selective for Strep. pneumoniae in sputum specimens containing other organisms and is also sensitive, being only marginally ...

journal_title：Journal of clinical pathology

authors： Nichols T,Freeman R

更新日期：1980-08-01 00:00:00

abstract：:The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on ...

journal_title：Journal of clinical pathology

authors： NOBLE WC,WILLIAMS RE,JEVONS MP,SHOOTER RA

更新日期：1964-01-01 00:00:00

abstract：:Performance of CHROMagar Acinetobacter was assessed for the selective isolation and identification of Acinetobacter baumannii. The medium was effective in suppressing the growth of other Gram-positive and Gram-negative species while the addition of KPC supplement ensured growth of only carbapenem resistant A baumannii...

journal_title：Journal of clinical pathology

authors： Wareham DW,Gordon NC

更新日期：2011-02-01 00:00:00

abstract：:Nearly two thousand clinical samples were examined by direct gas-liquid chromatography over a three year period. Absence of volatile fatty acids (VFAs) in the samples correlated well with negative culture results for anaerobic bacteria. In general the presence of acetic acid alone correlated well with the presence of ...

journal_title：Journal of clinical pathology

authors： Watt B,Geddes PA,Greenan OA,Napier SK,Mitchell A

更新日期：1982-07-01 00:00:00

abstract：:The principal neuropathological and general pathological findings in a group of 24 patients with renal transplants who died in a nine-year period at the Western Infirmary, Glasgow, are described. Opportunistic infections--bacterial, protozoal, and fungal--were the commonest causes of death. Other causes included cardi...

journal_title：Journal of clinical pathology

authors： Morton R,Graham DI,Briggs JD,Hamilton DN

更新日期：1982-01-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the mismatch repair gene expression and their correlation with NF-kB in patients with oral squamous cell carcinoma (SCC). METHODS:Total RNA was isolated from 28 biopsy samples. A control group was composed of 20 volunteers. Differential expression of hMSH2, hMSH6 and NF-kB ge...

journal_title：Journal of clinical pathology

authors： Fonseca A,Perez M,Veiga G,Prosdócimi F,Nunes F,Bianco B,Fonseca F,Alves B

更新日期：2020-05-01 00:00:00

abstract：:Myelomatosis was diagnosed in a 64 year old man on the basis of a serum paraprotein band (type IgG lambda, 42 g/l), plasma cell infiltration of bone marrow, and multiple lytic lesions evident on skull x ray picture. Blood specimens taken into plain glass tubes showed bulky gelatinous clot formation with minimal clot r...

journal_title：Journal of clinical pathology

authors： O'Kane MJ,Wisdom GB,Desai ZR,Archbold GP

更新日期：1994-03-01 00:00:00

abstract：:Of the first 166 heart and 15 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 162 were investigated for cytomegalovirus (CMV) infection by serological methods. Altogether, 73 (45%) developed CMV infection after transplantation: 30 (18.5%...

journal_title：Journal of clinical pathology

authors： Wreghitt TG,Hakim M,Gray JJ,Kucia S,Wallwork J,English TA

更新日期：1988-06-01 00:00:00

abstract：AIMS:To determine the possible histogenesis of the intracranial variant of olfactory neuroblastoma. METHODS:Four specimens from three cases of intracranial olfactory neuroblastoma were studied by light microscopy and immuno-histochemistry, and electron microscopy in two cases. RESULTS:Light microscopical examination ...

journal_title：Journal of clinical pathology

authors： Banerjee AK,Sharma BS,Vashista RK,Kak VK

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Somatic mutations are important determinants of cancer behaviour and response to therapy. However, molecular testing in this context has a relatively low profile within the clinical community, despite publicity surrounding targeted therapies such as Herceptin. AIMS:As the testing process affects many stakeh...

journal_title：Journal of clinical pathology

authors： Wordsworth S,Buchanan J,Papanicolas I,Taylor J,Frayling I,Tomlinson I

更新日期：2008-06-01 00:00:00

abstract：INTRODUCTION:Bone marrow aspiration and biopsy is an invasive procedure associated with morbidity and mortality risk. We compared a powered bone marrow aspiration and biopsy device to the traditional method by relatively assessing pain scores, procedure times, biopsy capture rates, quality of material retrieved, and sa...

journal_title：Journal of clinical pathology

authors： Swords RT,Anguita J,Higgins RA,Yunes AC,Naski M,Padmanabhan S,Kelly KR,Mahalingam D,Philbeck T,Miller L,Puga TA,Giles FJ,Kinney MC,Brenner AJ

更新日期：2011-09-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the risk factors for proximal resection margin involvement and its impact on survival outcome in patients with proximal gastric cancer. METHODS:A total of 488 patients who underwent potentially curative resection for proximal gastric cancer were retrospectively reviewed. Clini...

journal_title：Journal of clinical pathology

authors： Zhao B,Lu H,Bao S,Luo R,Mei D,Xu H,Huang B

更新日期：2020-08-01 00:00:00

abstract：AIMS:To assess the occurrence of diagnostic delay in primary antibody deficiency in the period 1989-2002, since a similar study in 1989, and to assess the impact of UK national guidelines communicated in 1995. METHODS:A retrospective case note review was performed of 89 consecutive patients with antibody deficiency re...

journal_title：Journal of clinical pathology

authors： Seymour B,Miles J,Haeney M

更新日期：2005-05-01 00:00:00

abstract：:Visual differential counts were examined for efficiency, cost effectiveness, and staff acceptability within our laboratory. A comparison with the Hemalog D system was attempted. The advantages and disadvantages of each system are enumerated and discussed in the context of a large general hospital. ...

journal_title：Journal of clinical pathology

authors： Hudson MJ,Green AE

更新日期：1980-11-01 00:00:00

abstract：:The results have been compared of microbiological and radioisotope dilution (RID) assay of serum vitamin B12 by participants in national interlaboratory trials in Britain. There was wide variation between the individual participants, especially marked in the L. leichmannii microbiological assay and in the RID methods,...

journal_title：Journal of clinical pathology

authors： Mollin DL,Hoffbrand AV,Ward PG,Lewis SM

更新日期：1980-03-01 00:00:00

abstract：AIM:To examine tumour samples immunohistochemically for MUC1 (episialin), epidermal growth factor receptor (EGFR), and c-erbB-2, since the disruption of the cell-cell adhesion system by MUC1 and the c-erbB oncoprotein family is known to be important in the development of metastasis in human cancers. METHODS:93 tumour ...

journal_title：Journal of clinical pathology

authors： Guddo F,Giatromanolaki A,Koukourakis MI,Reina C,Vignola AM,Chlouverakis G,Hilkens J,Gatter KC,Harris AL,Bonsignore G

更新日期：1998-09-01 00:00:00

abstract：:Two groups of women with non-specific genital infection were treated for two weeks with tetracycline 250 mg six-hourly and minocycline 100 mg twice daily respectively. Cultures for yeasts were performed before treatment and at the end of the first and second weeks. Before treatment yeasts, mostly Candida albicans, wer...

journal_title：Journal of clinical pathology

authors： Oriel JD,Waterworth PM

更新日期：1975-05-01 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：:Mixed lymphocyte reactions (MLRs) were measured in 25 HLA-A, B and DR compatible sibling bone marrow transplants. Only four of 25 MLRs were positive and in these the low reactivity was of doubtful clinical importance. There was no correlation between MLR and the subsequent development or severity of graft versus host ...

journal_title：Journal of clinical pathology

authors： Lim SH,Patton WN,Jobson S,Gentle TA,Baynham M,Franklin IM,Broughton BJ

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor (EGFR) gene mutation at the kinase domain and EGFR gene amplification are reported to be predictors of the response to EGFR tyrosine kinase inhibitors in lung cancer cases. In malignant mesothelioma (MM), the role of EGFR is less clear. METHODS:Thirty-eight MM specimens were...

journal_title：Journal of clinical pathology

authors： Enomoto Y,Kasai T,Takeda M,Takano M,Morita K,Kadota E,Iizuka N,Maruyama H,Haratake J,Kojima Y,Ikeda N,Inatsugi N,Nonomura A

更新日期：2012-06-01 00:00:00

abstract：:Routine anaerobic culture of urine identified the urinary tract as the primary focus of sepsis in a postoperative patient with Bacteroides fragilis septicaemia. Specimens of urine from six other symptomatic patients grew > 10(8) cfu/litre of a Bacteroides species in pure growth. The significance of these isolates is d...

journal_title：Journal of clinical pathology

authors： Bannon J,Hatem MH,Noone M

更新日期：1998-09-01 00:00:00