Principal neuropathological and general necropsy findings in 24 renal transplant patients.

abstract：:A 45-year-old man is described in whom there is currently ERCP and histological evidence of primary sclerosing cholangitis (PSC). A liver biopsy obtained 29 years ago shows similar histological features confirming that he had PSC at that time. This case indicates that PSC may follow a relatively benign course. ...

journal_title：Journal of clinical pathology

authors： Goudie BM,Birnie GG,Watkinson G,MacSween RN

更新日期：1983-11-01 00:00:00

abstract：AIMS:To determine whether myelodysplastic syndromes (MDS) are associated with sea blue histiocytosis in the bone marrow. METHODS:A retrospective review of bone marrow aspirates from 35 patients presenting consecutively with MDS and from 20 patients with each of the following: normal marrow appearance (routine staging ...

journal_title：Journal of clinical pathology

authors： Howard MR,Kesteven PJ

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Although Bulgaria has one of the highest rates of cervical cancer incidence and mortality in the EU, data on HPV type distribution are limited. AIM:To determine the prevalence of HPV types 16 and 18 in archival specimens from cervical cancer cases from Bulgaria. METHODS:A total of 145 formalin-fixed, paraf...

journal_title：Journal of clinical pathology

authors： Todorova I,Ganchev G,Shikova E

更新日期：2010-12-01 00:00:00

abstract：:The lymphoid tissue of the normal colon is compared with that of colons with diverticular disease. Colons with diverticular disease show a significant increase in the number of lymphoid nodules in areas not containing diverticula. Lymphoid-glandular complexes of the colon were studied in relation to diverticular disea...

journal_title：Journal of clinical pathology

authors： Kealy WF

更新日期：1976-03-01 00:00:00

abstract：:The separation of mesothelial hyperplasia from early malignant mesothelioma remains one of the most difficult problems in histopathology. Inconclusive cases are termed "atypical mesothelial hyperplasia" and treated expectantly. A 49 year old male pipeline engineer was diagnosed as having atypical mesothelial hyperplas...

journal_title：Journal of clinical pathology

authors： Scurry J,Duggan MA

更新日期：1999-07-01 00:00:00

abstract：:A biochemical typing method is described for Klebsiella pneumoniae (sensu lato) and Enterobacter aerogenes. The technique depends on differences in metabolism of five carbon substrates--glycerol, inositol, lactose, glucose, and xylose--at two concentrations. Reproducibility is satisfactory and is monitored by the inco...

journal_title：Journal of clinical pathology

authors： Barr JG,Hogg GM

更新日期：1979-09-01 00:00:00

abstract：:Five hundred and seven strains of bacteria isolated from the urine of patients with significant bacteriuria (more than 10(8) colony-forming units per litre) were tested for sensitivity to co-trimoxazole by the agar diffusion technique. Each organism was tested with a combined disk containing trimethoprim and sulphamet...

journal_title：Journal of clinical pathology

authors： Amyes SG,Telfer Brunton WA

更新日期：1981-02-01 00:00:00

abstract：:The 24-hour urinary excretion of cyclic 3',5'-adenosine monophosphate (cAMP) was measured by a protein-binding assay in 55 healthy volunteers (aged 20-35 yr) and in 30 hospitalized elderly subjects (aged 70-93 yr). In the older subjects the mean 24-hour cAMP excretion was significantly lower; the correlation between c...

journal_title：Journal of clinical pathology

authors： Gennari C,Galli M,Montagnani M

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF) is the most common skin lymphoid neoplasm. In initial stages, differential diagnosis of MF from other benign dermal lymphoid infiltrates (BDLI) may be impossible on morphological basis alone. In previous studies, only deletion of CD7 in MF proved to be of diagnostic help, but not the r...

journal_title：Journal of clinical pathology

authors： Lira M,Schenka AA,Magna LA,Cotta AC,Cintra ML,de Souza EM,Brousset P,Vassallo J

更新日期：2008-02-01 00:00:00

abstract：AIMS/BACKGROUND:Telomerase, an enzyme associated with cellular immortality, is expressed by most malignant tumours, but is inactive in normal somatic cells except for male germ cells and proliferating stem cells. Thus, the measurement of telomerase activity in tissue samples may provide useful diagnostic and prognostic...

journal_title：Journal of clinical pathology

authors： Yashima K,Piatyszek MA,Saboorian HM,Virmani AK,Brown D,Shay JW,Gazdar AF

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Parafibromin is a novel protein product of HRPT2, a recently identified tumour suppressor gene. Mutations of the HRPT2 gene are common in parathyroid carcinomas, and these exhibit reduced protein expression. Parafibromin expression in breast cancer has not been previously studied. AIMS:To determine the dist...

journal_title：Journal of clinical pathology

authors： Selvarajan S,Sii LH,Lee A,Yip G,Bay BH,Tan MH,Teh BT,Tan PH

更新日期：2008-01-01 00:00:00

abstract：:The test is an application of the method originally described by Boyden (1951) and adapted by Stavitsky and Arquilla (1958). Sera which contain anti-Panton-Valentine leucocidin agglutinate the prepared red cells, often to a very high dilution, and this has provided a useful serological test for the diagnosis of staphy...

journal_title：Journal of clinical pathology

authors： TOWERS AG

更新日期：1961-03-01 00:00:00

abstract：INTRODUCTION:Bone marrow aspiration and biopsy is an invasive procedure associated with morbidity and mortality risk. We compared a powered bone marrow aspiration and biopsy device to the traditional method by relatively assessing pain scores, procedure times, biopsy capture rates, quality of material retrieved, and sa...

journal_title：Journal of clinical pathology

authors： Swords RT,Anguita J,Higgins RA,Yunes AC,Naski M,Padmanabhan S,Kelly KR,Mahalingam D,Philbeck T,Miller L,Puga TA,Giles FJ,Kinney MC,Brenner AJ

更新日期：2011-09-01 00:00:00

abstract：:Sink drains in a medical-surgical intensive care unit (ICU) were cultured during six consecutive weeks as part of a seven month prospective study of acquisition of Pseudomonas aeruginosa by ICU patients. Isolates were typed serologically and by aminoglycoside and chlorhexidine susceptibility patterns. All 11 sinks con...

journal_title：Journal of clinical pathology

authors： Levin MH,Olson B,Nathan C,Kabins SA,Weinstein RA

更新日期：1984-04-01 00:00:00

abstract：AIMS:Low-grade myofibroblastic sarcoma (LGMS) represents a rare soft tissue neoplasm with a predilection for the head and neck. Intra-abdominal LGMS are rare with only four unequivocal examples reported so far. Two further cases in females in their 60s and 70s are analysed here. METHODS:Immunohistochemical stains were...

journal_title：Journal of clinical pathology

authors： Agaimy A,Wünsch PH,Schroeder J,Gaumann A,Dietmaier W,Hartmann A,Hofstaedter F,Mentzel T

更新日期：2008-03-01 00:00:00

abstract：:The clinical features and special investigations in a case of multiple myelomatosis are described. The finding of exfoliated ;myeloma cells' in the urine of this case is thought to be unique, these cells closely resembling the myeloma cells seen in the bone marrow. The necropsy findings indicated that the origin of th...

journal_title：Journal of clinical pathology

authors： PROWSE CM,BLECHER TE

更新日期：1962-03-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) to measure free serum IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis was developed. Seven strains of P aeruginosa cells, treated with glutaraldehyde and representing the most commonly isolated serotypes in our cystic fibrosis unit, were used. The ...

journal_title：Journal of clinical pathology

authors： Brett MM,Ghoneim AT,Littlewood JM,Losowsky MS

更新日期：1986-10-01 00:00:00

abstract：:Most patients with gonadoblastoma have dysgenetic gonads. This rare tumour has been described in three pregnant women. A fourth case in a 26 year old pregnant woman who presented with gonadoblastoma and dysgerminoma, is reported. She had a normal term pregnancy, 46XX chromosomes, normal genitalia, no history of menstr...

journal_title：Journal of clinical pathology

authors： Erhan Y,Toprak AS,Ozdemir N,Tiras B

更新日期：1992-09-01 00:00:00

abstract：AIMS:To investigate the histopathological changes in the livers of patients undergoing cholecystectomy and to relate these changes to the underlying biliary tract pathology. METHODS:Liver changes in 67 patients undergoing cholecystectomy were investigated. Sixty three had gall stones, one cholesterolosis only, and the...

journal_title：Journal of clinical pathology

authors： Geraghty JM,Goldin RD

更新日期：1994-05-01 00:00:00

abstract：:An indirect method of an enzyme-linked immunosorbent assay (ELISA) is described to assess the reactivity of antisera used for the identification of peptide hormone producing cells by immunocytochemistry. Compared with radioimmunoassay and immunodiffusion, the ELISA method has the advantages of simplicity and sensitivi...

journal_title：Journal of clinical pathology

authors： Nierwenhuijzen Kruseman AC

更新日期：1983-04-01 00:00:00

abstract：:Mixed lymphocyte reactions (MLRs) were measured in 25 HLA-A, B and DR compatible sibling bone marrow transplants. Only four of 25 MLRs were positive and in these the low reactivity was of doubtful clinical importance. There was no correlation between MLR and the subsequent development or severity of graft versus host ...

journal_title：Journal of clinical pathology

authors： Lim SH,Patton WN,Jobson S,Gentle TA,Baynham M,Franklin IM,Broughton BJ

更新日期：1988-11-01 00:00:00

abstract：:This review focuses on the pathological features of dysplasia in Barrett's oesophagus. Two categorisation schemes are used for grading dysplasia in the gastrointestinal tract, including Barrett's oesophagus. The inflammatory bowel disease dysplasia morphology study group system is the one most commonly used in the USA...

journal_title：Journal of clinical pathology

authors： Odze RD

更新日期：2006-10-01 00:00:00

abstract：:Histological examination of the lower margin of the internal sphincter has demonstrated an increased amount of fibrous tissue in patients with haemorrhoids compared with controls. This finding may be of relevance to the treatment of haemorrhoids by maximal anal dilatation. ...

journal_title：Journal of clinical pathology

authors： Haqqani MT,Hancock BD

更新日期：1978-03-01 00:00:00

abstract：:Bilateral adrenalectomy produces a reduction in the alkaline phosphatase concentration in rat intestine, which is not prevented by the administration of saline, but is prevented by the administration of cortisone. The administration of A.C.T.H. to normal rats leads to a rise in intestinal alkaline phosphatase levels a...

journal_title：Journal of clinical pathology

authors： Watson WC,Murray ES,Gardner MD

更新日期：1967-03-01 00:00:00

abstract：:Idoxuridine-treated McCoy cells grown as monolayers in 96 well microplates provide a convenient method for the isolation of Chlamydia trachomatis. Staining of infected monolayers with periodic acid-Schiff reagent (PAS) allows easy recognition of C trachomatis inclusions without the need for dark-ground microscopy. By ...

journal_title：Journal of clinical pathology

authors： Mallinson H,Sikotra S,Arya OP

更新日期：1981-07-01 00:00:00

abstract：:A radial immunodiffusion technique has been used to measure levels of four serum proteins in preeclampsia with or without proteinuria and in normal pregnant and non-pregnant controls. In preeclampsia unaccompanied by proteinuria, albumin and transferrin levels are similar to those found in the normal pregnant controls...

journal_title：Journal of clinical pathology

authors： Horne CH,Howie PW,Goudie RB

更新日期：1970-09-01 00:00:00

abstract：AIMS:Glypican 3 (GPC3) is a heparan sulphate proteoglycan that shows elevated levels in the serum of patients with hepatocellular carcinoma (HCC), but not in healthy blood donors or patients with benign liver disease. This study explores the value of GPC3 expression for diagnosis of HCC by immunohistochemistry in liver...

journal_title：Journal of clinical pathology

authors： Wang FH,Yip YC,Zhang M,Vong HT,Chan KI,Wai KC,Wen JM

更新日期：2010-07-01 00:00:00

abstract：:Group-specific polysaccharides of Neisseria meningitidis groups A and C have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. In this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by ...

journal_title：Journal of clinical pathology

authors： Severin WP

更新日期：1972-12-01 00:00:00

abstract：BACKGROUND:Cytokeratin immunohistochemistry (IHC) reveals a higher rate of occult lymph node metastases among lobular carcinomas than among ductal breast cancers. IHC is widely used but is seldom recommended for the evaluation of sentinel lymph nodes in breast cancer patients. OBJECTIVE:To assess the value of cytokera...

journal_title：Journal of clinical pathology

authors： Cserni G,Bianchi S,Vezzosi V,Peterse H,Sapino A,Arisio R,Reiner-Concin A,Regitnig P,Bellocq JP,Marin C,Bori R,Penuela JM,Iturriagagoitia AC

更新日期：2006-05-01 00:00:00

abstract：:Haemoglobin, haematocrit, and plasma iron values were estimated on blood samples collected from 100 male and 113 female National Blood Transfusion Service blood donors, and from 83 male and 66 female age-matched control subjects. No significant differences in any of these values were found to exist between the donors ...

journal_title：Journal of clinical pathology

authors： French EA,Sitlani PK

更新日期：1969-11-01 00:00:00