Pseudomonas in the sinks in an intensive care unit: relation to patients.

Abstract:

:Sink drains in a medical-surgical intensive care unit (ICU) were cultured during six consecutive weeks as part of a seven month prospective study of acquisition of Pseudomonas aeruginosa by ICU patients. Isolates were typed serologically and by aminoglycoside and chlorhexidine susceptibility patterns. All 11 sinks contained multiple strains of P aeruginosa; some strains persisted for weeks while others were isolated once. Of the sink isolates 56% had high level resistance to gentamicin and tobramycin whereas none of the strains found in patients. In sink isolates chlorhexidine resistance correlated with aminoglycoside resistance and with the presence of a chlorhexidine dispenser at a sink. The sequence of recovery of phenotypically similar isolates suggested that sinks were the source of at most two acquisitions of P aeruginosa by patients during the six weeks. Our study confirms that sinks may be reservoirs for large numbers of highly resistant P aeruginosa but are rarely the source of organisms colonising patients in our ICU.

journal_name

J Clin Pathol

authors

Levin MH,Olson B,Nathan C,Kabins SA,Weinstein RA

doi

10.1136/jcp.37.4.424

subject

Has Abstract

pub_date

1984-04-01 00:00:00

pages

424-7

issue

4

eissn

0021-9746

issn

1472-4146

journal_volume

37

pub_type

杂志文章
  • Lymphoid tissue and lymphoid-glandular complexes of the colon: relation to diverticulosis.

    abstract::The lymphoid tissue of the normal colon is compared with that of colons with diverticular disease. Colons with diverticular disease show a significant increase in the number of lymphoid nodules in areas not containing diverticula. Lymphoid-glandular complexes of the colon were studied in relation to diverticular disea...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.29.3.245

    authors: Kealy WF

    更新日期:1976-03-01 00:00:00

  • Bacteriocine typing of Proteus.

    abstract::A method of typing isolates of Proteus mirabilis and Proteus vulgaris is described based on the sensitivity of the organisms to bacteriocine. Twelve standard proteocine producing strains were selected from a large number of isolates tested, and from these liquid proteocine preparations were prepared. The sensitivities...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.28.10.784

    authors: Al-Jumaili IJ

    更新日期:1975-10-01 00:00:00

  • The diagnostic challenge of congenital dyserythropoietic anaemia: two cases of 'CDA type II'.

    abstract::The congenital dyserythropoietic anaemias (CDAs) are a group of rare hereditary disorders characterised by ineffective erythropoiesis and morphological abnormalities in the erythroblasts. Patients may present with jaundice or with symptoms of anaemia, gall stones or iron overload. The diagnosis can be challenging and ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2013-201779

    authors: Dukka S,King MJ,Hill QA

    更新日期:2014-04-01 00:00:00

  • Molecular testing for somatic mutations in common cancers: the views of UK oncologists.

    abstract:BACKGROUND:Somatic mutations are important determinants of cancer behaviour and response to therapy. However, molecular testing in this context has a relatively low profile within the clinical community, despite publicity surrounding targeted therapies such as Herceptin. AIMS:As the testing process affects many stakeh...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.2007.054510

    authors: Wordsworth S,Buchanan J,Papanicolas I,Taylor J,Frayling I,Tomlinson I

    更新日期:2008-06-01 00:00:00

  • Implementing NGS-based BRCA tumour tissue testing in FFPE ovarian carcinoma specimens: hints from a real-life experience within the framework of expert recommendations.

    abstract:AIMS:Next Generation Sequencing (NGS)-based BRCA tumour tissue testing poses several challenges. As a first step of its implementation within a regional health service network, an in-house validation study was compared with published recommendations. METHODS:Epithelial ovarian cancer (EOC) formalin-fixed paraffin-embe...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2020-206840

    authors: Rivera D,Paudice M,Gismondi V,Anselmi G,Vellone VG,Varesco L,Ligurian BRCA Working Group.

    更新日期:2020-09-07 00:00:00

  • Immunocytological staining reactions of anti-carcinoembryonic antigen, Ca, and anti-human milk fat globule monoclonal antibodies on benign and malignant exfoliated mesothelial cells.

    abstract::A panel of three monoclonal antibodies were used in an immunoalkaline phosphatase staining method on a series of serous effusion samples from cases of mesothelioma, lung carcinoma, and benign disease. The antibodies used were anti-carcinoembryonic (CEA) antigen, Ca, and anti-human milk fat globule membrane antigen. An...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.40.12.1424

    authors: Ghosh AK,Butler EB

    更新日期:1987-12-01 00:00:00

  • Endothelial nitric oxide synthase immunoreactivity in early gestation and in trophoblastic disease.

    abstract:AIMS:To study the localisation of the endothelial nitric oxide synthase (eNOS) in the normal placenta, with special emphasis on the implantation site in the first trimester of pregnancy, and in the different subtypes of trophoblastic cells in gestational trophoblastic disease. METHODS:The immunoperoxidase technique wi...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.51.6.427

    authors: Ariel I,Hochberg A,Shochina M

    更新日期:1998-06-01 00:00:00

  • Structure and ultrastructure of the labial salivary glands in patients with cystic fibrosis.

    abstract::The morphology of the labial salivary glands in subjects with and without cystic fibrosis has been studied by light and electron microscopy. The terms ;light' cell, ;dark' cell, ;clear' cell, and ;myoepithelial' cell are used to describe the four cell types distinguished at the level of the electron microscope. The da...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.24.3.270

    authors: Doggett RG,Bentinck B,Harrison GM

    更新日期:1971-04-01 00:00:00

  • Histological evidence of initiating factors in acute necrotising pancreatitis in man.

    abstract::In this necropsy review of 37 cases of acute pancreatitis, evidence is presented that there are at least two different initiating mechanisms in acute necrotising pancreatitis in man. Firstly, there is primary duct inflammation, with subsequent inflammation and necrosis of the pancreatic parenchyma surrounding the excr...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.33.12.1125

    authors: Foulis AK

    更新日期:1980-12-01 00:00:00

  • Coxsackie B virus infection in coronary care unit patients.

    abstract::It has been suggested that Coxsackie B virus infections may play a part in causing or triggering myocardial infarction. This study was designed to compare the incidence of such infections in Coronary Care Unit patients and normal controls. The choice of a suitable criterion for diagnosis of Coxsackie infection is disc...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.36.6.658

    authors: O'Neill D,McArthur JD,Kennedy JA,Clements G

    更新日期:1983-06-01 00:00:00

  • Some interactions between human platelets and glass: von Willebrand's disease compared with normal.

    abstract::If native or heparinized blood is passed slowly through a column of glass beads at room temperature, the number of platelets removed from the initial drop emerging from the column is less than that removed from the final drop. At 4 degrees C. this difference disappears. If the blood is passed rapidly through such colu...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.20.1.56

    authors: O'Brien JR,Heywood JB

    更新日期:1967-01-01 00:00:00

  • Comparison of antisera in the fluorescent antibody test for detection of Bacteroides spp in clinical specimens.

    abstract::Twenty-two known strains of the Bacteroides fragilis group of organisms and 67 clinical specimens from a variety of sites were examined by fluorescent antibody test (IFA) using two different antisera fro the rapid detection of B fragilis group of organisms. A previously reported Barts' pooled antisera was compared wit...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.35.3.304

    authors: Wills A,Taylor E,Pantosti A,Phillips I,Tabaqchali S

    更新日期:1982-03-01 00:00:00

  • Lymphocytic gastritis-like T cell lymphoma: molecular evidence of an unusual recurrence.

    abstract::This report describes a patient with a gastric biopsy specimen showing histomorphological and immunohistochemical appearances indistinguishable from those usually present in lymphocytic gastritis, a rare condition of unknown aetiology with a distinctive phenotype. The patient had a history of a biopsy confirmed T cell...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.2004.017350

    authors: Nga ME,Tan SH,Teh M,Koay ES,Chong SM,Putti TC,Salto-Tellez M

    更新日期:2004-11-01 00:00:00

  • Inverted hyperplastic polyposis of the colon.

    abstract:AIMS:To describe and evaluate two apparently unique cases of inverted hyperplastic (metaplastic) polyposis of the colon. METHODS:The cases were analysed by standard histopathological, histochemical, and immunohistochemical techniques and the findings compared with those of regular hyperplastic polyps of the colorectum...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.46.1.56

    authors: Shepherd NA

    更新日期:1993-01-01 00:00:00

  • Continuous assessment of performance in External Quality Assessment Schemes.

    abstract::A simple, standardised procedure was used for processing data from External Quality Assessment Schemes and for producing performance charts. A graphic presentation of cumulative performance is generated for each test, using an integrated software package to display results in a standardised format. This permits interp...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.44.1.17

    authors: Ardern JC,Hyde K,Hickman L,Urmston A,Burgess R,Burn AM,Geary CG

    更新日期:1991-01-01 00:00:00

  • Diagnostic equipment outside the laboratory.

    abstract::A questionnaire was circulated to clinical biochemistry laboratories in the North West Thames region of the United Kingdom requesting information on extralaboratory equipment. Data on the types and numbers of instruments in use, their relationship with the laboratory, and quality assurance procedures were obtained. La...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.41.9.925

    authors: Burrin JM,Fyffe JA

    更新日期:1988-09-01 00:00:00

  • Detection of circulating fetal nucleic acids: a review of methods and applications.

    abstract::The discovery of cell-free circulating fetal nucleic acids in maternal plasma has opened up new possibilities in non-invasive prenatal diagnosis. The rapid advancement of this field in the past decade is catalysed by the discovery of new classes of fetal nucleic acid markers and technological developments in nucleic a...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1136/jcp.2007.048470

    authors: Hung EC,Chiu RW,Lo YM

    更新日期:2009-04-01 00:00:00

  • How morphometric analysis of metastatic load predicts the (un)usefulness of PET scanning: the case of lymph node staging in melanoma.

    abstract:BACKGROUND:In primary cutaneous melanoma, the sentinel node (SN) biopsy is an accurate method for the staging of the lymph nodes. Positron emission tomography (PET) has been suggested as a useful alternative. However, the sensitivity of PET may be too low to detect SN metastases, which are often small. AIM:To predict ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.56.4.283

    authors: Mijnhout GS,Hoekstra OS,van Lingen A,van Diest PJ,Adèr HJ,Lammertsma AA,Pijpers R,Meijer S,Teule GJ

    更新日期:2003-04-01 00:00:00

  • Electron microscopic findings of parallel tubular granules in a case of chronic neutrophilic leukaemia.

    abstract::A case of chronic neutrophilic leukaemia (CNL) is reported. The diagnosis was based on leucocytosis with mature neutrophils, a raised leucocyte alkaline phosphatase score, negative Philadelphia chromosome, and extensive infiltration of neutrophils in various differentiation stages into the bone marrow. When viewed by ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.47.4.367

    authors: Takemori N,Hirai K,Onodera R,Saito N,Namiki M

    更新日期:1994-04-01 00:00:00

  • Artificial factor VIII deficient plasma: preparation using monoclonal antibodies and its use in one stage coagulation assays.

    abstract::Monoclonal antibodies to factor VIII antigen (VIII:Ag) and von Willebrand factor (vWf:Ag) were immobilised on Sephacryl S-1000 and tested for their ability to deplete normal human citrated plasma of factor VIII. A combination of two antibodies to VIII:Ag and one antibody to vWf:Ag was required to produce plasma contai...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.41.5.562

    authors: Hornsey VS,Waterston YG,Prowse CV

    更新日期:1988-05-01 00:00:00

  • Modification of Michaëlsson's method for the measurement of plasma total bilirubin.

    abstract::Michaëlsson's (1961) method for the measurement of plasma bilirubin concentration was found to be complicated by conjugated bilirubin. Delaying the addition of the accelerator, diphylline, corrected this fault. The method was calibrated using serum or plasma, since reconstituted protein solutions introduced large erro...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.22.4.439

    authors: Thompson RP

    更新日期:1969-07-01 00:00:00

  • Increased stool sampling during a waterborne outbreak of cryptosporidiosis does not increase the detection of other faecal pathogens.

    abstract:AIMS:To ascertain the effect of enhanced surveillance following an outbreak of waterborne cryptosporidiosis on the number of faecal specimens submitted to the local microbiology laboratory and the number positive for common enteric pathogens. The outbreak provided an opportunity to estimate the extent of routine under ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.55.4.271

    authors: Qamruddin AO,Keaney MG,McCann R,Chadwick PR

    更新日期:2002-04-01 00:00:00

  • Use of histological examination to assess ultrastructure of liver in patients with long standing jejuno-ileal bypass for morbid obesity.

    abstract::To assess the pattern and severity of liver disease in patients who had undergone jejuno-ileal bypass for the treatment of morbid obesity, 23 patients were biopsied, all of whom had had intact bypasses for more than 10 years. These were examined by light and electron microscopy. Previous biopsy specimens from each pat...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.41.12.1281

    authors: Boon AP,Thompson H,Baddeley RM

    更新日期:1988-12-01 00:00:00

  • Coexistence of an endocrine tumour in a serous cystadenoma (microcystic adenoma) of the pancreas, an unusual association.

    abstract::A pancreatic endocrine tumour arising within a serous cystadenoma is reported. A 49 year old woman was admitted with a history of epigastric pain, nausea, vomiting, and weight loss of two months duration. She had been diabetic for 12 years. An epigastric mass was palpated in the physical examination, and computed tomo...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.53.10.800

    authors: Ustün MO,Tuğyan N,Tunakan M

    更新日期:2000-10-01 00:00:00

  • Tracheopathia osteoplastica.

    abstract::Only four cases of tracheopathia osteoplastica have been reported in Britain in the past 110 years. Ten further cases are now reported; in two the diagnosis was made at bronchoscopy. It is suggested that the reputed rarity of the condition in Britain is not the whole picture. ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.20.6.814

    authors: Way SP

    更新日期:1967-11-01 00:00:00

  • Pathologists dislike sound? Evaluation of a computerised training microscope.

    abstract:AIM:To evaluate the use of multimedia enhancements, using a computerised microscope, in the training of microscope skills. METHODS:The HOME microscope provides facilities to highlight features of interest in conjunction with either text display or aural presentation. A pilot study was carried out with 10 individuals, ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.51.4.330

    authors: Gray E,Duvall E,Sprey J,Bird CC

    更新日期:1998-04-01 00:00:00

  • A new selective medium for Streptococcus pneumoniae.

    abstract::The development and evaluation of a new selective medium for Streptococcus pneumoniae is described. It is shown that the new medium (crystal violet-nalidixic acid-gentamicin agar:CVNG) is highly selective for Strep. pneumoniae in sputum specimens containing other organisms and is also sensitive, being only marginally ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.33.8.770

    authors: Nichols T,Freeman R

    更新日期:1980-08-01 00:00:00

  • Aetiology, pathogenesis, and pathology of cervical neoplasia.

    abstract::Early epidemiological studies of cervical neoplasia suggested a causal relation with sexual activity and human papillomaviruses (HPVs) have emerged as prime suspects as venerally transmitted carcinogens. HPVs fall into two broad camps: low risk types, associated with cervical condylomas and CIN 1; and high risk types ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1136/jcp.51.2.96

    authors: Arends MJ,Buckley CH,Wells M

    更新日期:1998-02-01 00:00:00

  • Antithrombin activities in childhood malnutrition.

    abstract::Antithrombin activities in 30 severely malnourished children and 40 normal children were estimated in clotting tests by thrombin neutralisation as anti-Xa and by a heparin antithrombin assay; and by immunodiffusion as alpha 2-globulin and alpha 1-antitrypsin. The patients' mean alpha 2-globulin was severely depressed,...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.32.10.1025

    authors: Jiménez RA,Jiménez E,Ingram GI,Mora LA,Atmetlla F,Carrillo JM,Vargas W

    更新日期:1979-10-01 00:00:00

  • Coverage analysis in a targeted amplicon-based next-generation sequencing panel for myeloid neoplasms.

    abstract:AIMS:PCR amplicon-based next-generation sequencing (NGS) panels are increasingly used for clinical diagnostic assays. Amplification bias is a well-known limitation of PCR amplicon-based approaches. We sought to characterise lower-performance amplicons in an off-the-shelf NGS panel (TruSight Myeloid Sequencing Panel) fo...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2015-203580

    authors: Yan B,Hu Y,Ng C,Ban KH,Tan TW,Huan PT,Lee PL,Chiu L,Seah E,Ng CH,Koay ES,Chng WJ

    更新日期:2016-09-01 00:00:00