Electron microscopic findings of parallel tubular granules in a case of chronic neutrophilic leukaemia.

abstract：:A case of IgD myeloma accompanied by diffuse osteosclerosis is reported. A trephine biopsy specimen showed only reticulin fibrosis, but histomorphometric analysis of a full thickness transiliac bone biopsy specimen showed increased trabecular bone mass, with no local deposit of tumour. An excess of bone surfaces were ...

journal_title：Journal of clinical pathology

authors： MacCallum PK,Freemont AJ,Geary CG,Liu Yin JA

更新日期：1988-05-01 00:00:00

abstract：AIMS:Venous invasion (VI) is a known independent prognostic indicator of recurrence and survival in colorectal cancer. The guidelines of the Royal College of Pathologists (RCPath) state that, in a series of resections, extramural VI should be detected in at least 25% of specimens. However, there is widespread variabili...

journal_title：Journal of clinical pathology

authors： Messenger DE,Driman DK,McLeod RS,Riddell RH,Kirsch R

更新日期：2011-11-01 00:00:00

abstract：:Publications describing aspects of the coccidian protozoan parasite Cryptosporidium, increased greatly during 1983 and 1984 as a result of not only increasing veterinary interest but also in the role of the parasite in the newly recognised acquired immune deficiency syndrome (AIDS). The reports reflected widespread co...

journal_title：Journal of clinical pathology

authors： Casemore DP,Sands RL,Curry A

更新日期：1985-12-01 00:00:00

abstract：AIMS:To compare intratumorous microvessel density (MVD) and clinicopathological features in two different groups of hepatocellular carcinoma (HCC), namely: hepatitis B virus (HBV) related HCC (B-HCC) and HCV related HCC (C-HCC). METHODS:Fifty consecutive cases each of B-HCC and of C-HCC were studied. Microvessel numbe...

journal_title：Journal of clinical pathology

authors： Messerini L,Novelli L,Comin CE

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori associated gastric cancer arises via a multistage process, with atrophic gastritis being the precursor lesion. Helicobacter pylori is typically acquired in childhood, yet little is known of the prevalence of atrophic gastritis in childhood. AIM:To study atrophic gastritis among children ...

journal_title：Journal of clinical pathology

authors： Ricuarte O,Gutierrez O,Cardona H,Kim JG,Graham DY,El-Zimaity HM

更新日期：2005-11-01 00:00:00

abstract：:A family with hypobetalipoproteinaemia was studied to examine the Lp(a) lipoprotein, lipoprotein cholesterol, and triglyceride composition of the serum lipids. Lp(a) lipoprotein was measured by immunoassay. Serum lipoproteins were separated by ultracentrifugation. Cholesterol and triglycerides were measured using stan...

journal_title：Journal of clinical pathology

authors： Crook M,Swaminathan R

更新日期：1995-06-01 00:00:00

abstract：AIMS:In the time of COVID-19, predictive molecular pathology laboratories must still timely select oncological patients for targeted treatments. However, the need to respect social distancing measures may delay results generated by laboratory-developed tests based on sequential steps a long hands-on time. Laboratory wo...

journal_title：Journal of clinical pathology

authors： Malapelle U,De Luca C,Iaccarino A,Pepe F,Pisapia P,Russo M,Sgariglia R,Nacchio M,Vigliar E,Bellevicine C,Schmitt FC,Troncone G

更新日期：2020-05-19 00:00:00

abstract：:Immunological methods of pregnancy diagnosis using both tanned red cell and latex particles are compared in a series of women (up to the fourteenth week of gestation) and also in negative controls. The tanned red cell test showed slightly more accurate and sensitive results throughout the trial. In 31 samples also sub...

journal_title：Journal of clinical pathology

authors： WORT AJ,VARDE KN,FAIRWEATHER DV,GREEN CA

更新日期：1963-11-01 00:00:00

abstract：AIMS:Our laboratory is a centralised centre receiving routine non-small cell lung cancer (NSCLC) samples for programmed death ligand-1 (PD-L1) immunohistochemical (IHC) evaluation. Since literature data are not concordant here we review our clinical records to assess the rate of PD-L1 positive and negative NSCLC cases ...

journal_title：Journal of clinical pathology

authors： Vigliar E,Malapelle U,Iaccarino A,Acanfora G,Pisapia P,Clery E,De Luca C,Bellevicine C,Troncone G

更新日期：2019-06-01 00:00:00

abstract：:The incidence of jaundice and of abnormal liver function tests has been assessed in 91 multitransfused patients with severe haemophilia A and B. Tests of hepatocyte function were within the normal range in the majority of patients. On the contrary, tests of biliary cell function, liver cell damage, and bromsulphthalei...

journal_title：Journal of clinical pathology

authors： Mannucci PM,Capitanio A,Del Ninno E,Colombo M,Pareti F,Ruggeri ZM

更新日期：1975-08-01 00:00:00

abstract：:The Scottish Meningococcus and Pneumococcus Reference Laboratory provides a national service for the laboratory confirmation of meningococcal and pneumococcal disease in Scotland. The main tests used for the laboratory confirmation of meningococcal disease are culture, the polymerase chain reaction (PCR), antibody tes...

journal_title：Journal of clinical pathology

authors： Clarke SC,Diggle MA,Reid JA,Thom L,Edwards GF

更新日期：2001-07-01 00:00:00

abstract：:Agar gel, cellulose acetate, and starch gel electrophoresis are all capable of diagnosing sickle-cell anaemia, sickle-cell haemoglobin C disease, and haemoglobin C disease in cord blood samples. Of these three electrophoretic techniques, agar gel is the easiest to interpret.Paper electrophoresis can reliably and rapid...

journal_title：Journal of clinical pathology

authors： Yaswon GI,Huntsman RG,Metters JS

更新日期：1970-09-01 00:00:00

abstract：:Immunoreactive trypsin (IRT) content in blood spots from 17 cystic fibrosis (CF) children born between 1975-80 were assayed with reagents from two commercial radioimmunoassay kits. The manufacturers' procedures were modified to allow assay of blood spot IRT. Half of the CF samples had a significantly raised IRT conten...

journal_title：Journal of clinical pathology

authors： Ryley HC,Robinson PG,Yamashiro Y,Bradley DM

更新日期：1981-08-01 00:00:00

abstract：AIM:To evaluate a new enzyme immunoassay (EIA) method for detection of Clostridium difficile toxin by comparing it to cytotoxicity assay. To investigate the nature of false negative and false positive EIA results by evaluating clinical and therapeutic parameters. METHODS:737 consecutive diarrhoeal specimens collected ...

journal_title：Journal of clinical pathology

authors： Vargas SO,Horensky D,Onderdonk AB

更新日期：1997-12-01 00:00:00

abstract：AIMS:To identify the amyloid protein in a patient with amyloidosis localised to the urinary bladder, and to see whether subtyping of the protein by sequence analysis increases the understanding of the selection of the urinary bladder as the site of amyloid deposition. METHODS:A patient with gross haematuria and a cong...

journal_title：Journal of clinical pathology

authors： Livneh A,Shtrasburg S,Martin BM,Baniel J,Gal R,Pras M

更新日期：2001-12-01 00:00:00

abstract：:A pancreatic endocrine tumour arising within a serous cystadenoma is reported. A 49 year old woman was admitted with a history of epigastric pain, nausea, vomiting, and weight loss of two months duration. She had been diabetic for 12 years. An epigastric mass was palpated in the physical examination, and computed tomo...

journal_title：Journal of clinical pathology

authors： Ustün MO,Tuğyan N,Tunakan M

更新日期：2000-10-01 00:00:00

abstract：:The API 20 STREP system was used to identify 146 known strains from seven species of the genus Listeria, including both pathogenic and environmental strains. The gallery was easy to use and tests, with the exception of leucine arylamidase (LAP) and starch fermentation (AMD), were simple to interpret. Identification to...

journal_title：Journal of clinical pathology

authors： MacGowan AP,Marshall RJ,Reeves DS

更新日期：1989-05-01 00:00:00

abstract：AIMS:The authors previously demonstrated that nasal mucus cyclic adenosine 3', 5'-monophosphate (cAMP) and cyclic 3', 5'-guanosine monophosphate (cGMP) were lower in patients with smell and taste dysfunction than in normal individuals. To learn more about these differences this study related levels of nasal mucus cAMP ...

journal_title：Journal of clinical pathology

authors： Henkin RI,Velicu I

更新日期：2012-05-01 00:00:00

abstract：:The distribution and quantitative expression of HBcAg in relation to serum HBeAg and liver histology before and after a trial of interferon in 50 patients with chronic type B hepatitis were evaluated using polyclonal and monoclonal antibodies. In general, both antisera showed a similar pattern in terms of the distribu...

journal_title：Journal of clinical pathology

authors： Chu CM,Lin SM,Liaw YF

更新日期：1991-01-01 00:00:00

abstract：:As part of a study to establish the prevalence of renal calculus disease, alkaline phosphatase activity was measured by the method recommended by the Scandinavian Society for Clinical Chemistry and Clinical Physiology in the plasma of 3823 adults from the Scottish new town of Cumbernauld. The enzyme activity differs i...

journal_title：Journal of clinical pathology

authors： Gardner MD,Scott R

更新日期：1978-12-01 00:00:00

abstract：AIMS:The purpose of this study was to compare the DNA-methylation signature in classic chronic Philadelphia negative myeloproliferative neoplasms (MPN), polycythaemia vera (PV) and essential thrombocythaemia (ET), in order to obtain a global insight into DNA-methylation changes associated with these malignancies. METH...

journal_title：Journal of clinical pathology

authors： Barrio S,Gallardo M,Albizua E,Jimenez A,Rapado I,Ayala R,Gilsanz F,Martin-Subero JI,Martinez-Lopez J

更新日期：2011-11-01 00:00:00

abstract：AIMS:Soft tissue tumours are a heterogeneous group of neoplasms that can arise at almost every anatomical site. As they often show similar clinical and radiological findings, histology is the definitive diagnostic method and it is crucial that the surgical pathology report contains accurate, useful information for mana...

journal_title：Journal of clinical pathology

authors： Shah C,Wang J,Mubako T,Fisher C,Thway K

更新日期：2016-09-01 00:00:00

abstract：:Starch gel electrophoresis has demonstrated that graded concentrations of sodium sulphate do not precipitate the serum globulins in any reasonable degree of purity. The use of this form of electrophoresis has shown that caeruloplasmin is associated with a globulin in the Fa(2) position.This technique can be employed a...

journal_title：Journal of clinical pathology

authors： CUMINGS JN,EARL CJ

更新日期：1960-01-01 00:00:00

abstract：:Sections from 100 cervical biopsy specimens were studied by 12 consultant histopathologists to determine the robustness of the existing pathology terminology and classification. Analysis by kappa statistics showed good agreement in the diagnosis of CIN 3 and squamous carcinoma but an inability to distinguish accuratel...

journal_title：Journal of clinical pathology

authors： Robertson AJ,Anderson JM,Beck JS,Burnett RA,Howatson SR,Lee FD,Lessells AM,McLaren KM,Moss SM,Simpson JG

更新日期：1989-03-01 00:00:00

abstract：:Tubercle bacilli, which survived heat fixation, were detected with a slide culture technique which allowed the entire smear to be examined. Both conventional flame fixation and the use of a controlled hot-plate failed to render tuberculous sputum smears safe for further handling. Smears which were stained with the ph...

journal_title：Journal of clinical pathology

authors： Allen BW

更新日期：1981-07-01 00:00:00

abstract：:Cancer lineage/tissue-of-origin assignment in cancers of unknown primary remains a challenge even when aided by massively parallel sequencing. The stakes are high for patients as many contemporary therapeutic strategies are disease-specific, and the biological differences can influence the patients' responses. Herein,...

journal_title：Journal of clinical pathology

authors： Yoon JY,Rosenbaum JN,Vergara N,Cohen RB,Wilson RB

更新日期：2020-08-27 00:00:00

abstract：:Two patients are reported in whom initial misdiagnoses of medullary cancer or trabecular hyaline adenoma for papillary carcinoma were made. ...

journal_title：Journal of clinical pathology

authors： Andrew AC,Williamson JM

更新日期：1993-08-01 00:00:00

abstract：:Malignant histiocytosis (histiocytic medullary reticulosis) in a 45-year-old white man is described. Unusual features were presentation as a surgical emergency with signs of obstruction and peritonitis due to an ileal tumour and extensive spindle cell differentiation. Problems in the differential diagnosis of malignan...

journal_title：Journal of clinical pathology

authors： Macgillivray JB,Duthie JS

更新日期：1977-02-01 00:00:00

abstract：:Michaëlsson's (1961) method for the measurement of plasma bilirubin concentration was found to be complicated by conjugated bilirubin. Delaying the addition of the accelerator, diphylline, corrected this fault. The method was calibrated using serum or plasma, since reconstituted protein solutions introduced large erro...

journal_title：Journal of clinical pathology

authors： Thompson RP

更新日期：1969-07-01 00:00:00

abstract：:Visceral botryomycosis is rare, and documented sites are lung, brain, kidney, liver and prostate. This report describes a rare autopsy case of disseminated visceral botryomycosis, with bulky, grape-like botryomycotic vegetations in the heart, and similar abscesses in the lungs and bone marrow. This is the first such r...

journal_title：Journal of clinical pathology

authors： Gupta K,Das A,Radotra BD,Bhalla A

更新日期：2008-08-01 00:00:00