Cardiac botryomycosis: an autopsy report.

abstract：:The relation between the choline containing surfactant phospholipids lecithin and sphingomyelin in amniotic fluid and fetal lung maturity is well established. An enzymatic method that had been automated and optimised for use on a centrifugal analyser was used to measure the total choline containing phospholipids in am...

journal_title：Journal of clinical pathology

authors： Teng SH,Andrews AG,Horacek I

更新日期：1985-11-01 00:00:00

abstract：:The isotopic estimation of the cortisol secretion rate in man is now an accepted and reliable method of assaying adrenal cortical function.Seven years' experience with its clinical use is reviewed and some practical aspects of technique are considered. The mean normal resting cortisol secretion rate is 16.2 +/- 5.7 mg...

journal_title：Journal of clinical pathology

authors： COPE CL,PEARSON J

更新日期：1965-01-01 00:00:00

abstract：:A rapid and reproducible technique for in situ hybridisation, using biotin labelled probes for the Y chromosome, human DNA, hepatitis B virus DNA and cytomegalovirus DNA on formalin fixed, paraffin embedded liver tissue, was developed. The degree of proteolytic digestion of tissue specimens is critical to ensure adequ...

journal_title：Journal of clinical pathology

authors： Naoumov NV,Alexander GJ,Eddleston AL,Williams R

更新日期：1988-07-01 00:00:00

abstract：:Factor VIII procoagulant activity (VIII:C), factor VIII related antigen (VIIIR:AG), and the von Willebrand factor (VIII:WF) were measured in 19 patients with liver disease (8 cases of alcoholic cirrhosis and 11 with acute viral hepatitis). In both groups of patients the levels of VIII:C, VIIIR:AG, and VIIIR:WF were ab...

journal_title：Journal of clinical pathology

authors： Maisonneuve P,Sultan Y

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:An increase in intraepithelial lymphocytes (IELs) is mandatory for the histological diagnosis of coeliac disease (CD). Currently, duodenal biopsies are used almost exclusively to establish the diagnosis, yet published work continues to cite an upper limit of 40 lymphocytes/100 epithelial cells, a figure deri...

journal_title：Journal of clinical pathology

authors： Hayat M,Cairns A,Dixon MF,O'Mahony S

更新日期：2002-05-01 00:00:00

abstract：AIMS:To elucidate potential mechanisms of drug resistance, levels of topoisomerase II alpha mRNA, a target for cytostatic drugs, were measured in cryopreserved tumour tissue from 36 patients with non-Hodgkin's lymphoma. To evaluate the potential association between topoisomerase II alpha and cell proliferation, Ki-67 i...

journal_title：Journal of clinical pathology

authors： Lohri A,Reuter J,Gudat F,Herrmann R

更新日期：1997-01-01 00:00:00

abstract：AIMS:Myospherulosis is a rare condition characterised by sac-like structures containing spheroid bodies in cysts or cystic spaces in the tissue. This condition has not previously been reported in the liver. The association with previous portal vein embolisation using a mixture of butyl 2-cyanoacrylate and ethiodised oi...

journal_title：Journal of clinical pathology

authors： Lui PC,Luk IS,Lee CK,Lui YH,Leung CY,Choi CH

更新日期：2004-02-01 00:00:00

abstract：:A rapid technique using a non-radioactive receptor molecule (digoxigenin) for intrahepatic hepatitis B virus (HBV) DNA detection using in situ hybridisation was developed. It can be adapted for use in combination with standard immunohistochemistry for simultaneous detection of both HBV DNA and HBV antigens. The total ...

journal_title：Journal of clinical pathology

authors： Lau JY,Naoumov NV,Alexander GJ,Williams R

更新日期：1991-11-01 00:00:00

abstract：AIMS:The aim of the present study was to immunohistochemically investigate the expression and prognostic significance of putative cancer stem cell markers CD117 (c-kit), CD34, CD20 and CD15 in a cohort of patients with primary choroidal and ciliary body melanoma. METHODS:The immunohistochemical expression of these mar...

journal_title：Journal of clinical pathology

authors： Lukenda A,Dotlic S,Vukojevic N,Saric B,Vranic S,Zarkovic K

更新日期：2016-03-01 00:00:00

abstract：:The effect of the new beta-lactam antibiotic FL 1060 on urinary tract pathogens, of which 71 were sensitive to and 100 resistant to ampicillin, is presented here. When tested by conventional methods FL 1060 was found to be highly active against ampicillin-sensitive strains of E. coli but phenotypically resistant varia...

journal_title：Journal of clinical pathology

authors： Greenwood D,Brooks HL,Gargan R,O'Grady F

更新日期：1974-03-01 00:00:00

abstract：:Rapid diagnoses were made on 510 breast lumps by three methods in sequence and the results compared with those obtained by paraffin histology.Naked-eye examination of the excised lumps correctly distinguished between benign and malignant tumours in 95.1% of cases with 23 (4.5%) false negative and two (0.4%) false posi...

journal_title：Journal of clinical pathology

authors： Tribe CR

更新日期：1973-04-01 00:00:00

abstract：:Preoperative (neoadjuvant) chemoradiation therapy/treatment (NCRT) is emerging as an important treatment modality in borderline resectable pancreatic ductal adenocarcinoma (PDAC). The constellation of histopathological changes secondary to chemoradiation is diverse and has been well documented, particularly in other g...

journal_title：Journal of clinical pathology

authors： Kalimuthu SN,Serra S,Dhani N,Chetty R

更新日期：2016-06-01 00:00:00

abstract：AIM:To compare the histological characteristics of Helicobacter pylori positive chronic gastritis in patients with and without associated duodenitis. METHODS:Gastric mucosal biopsy specimens were obtained from patients undergoing endoscopy for dyspepsia. Severity of gastritis and density of H pylori infection were gra...

journal_title：Journal of clinical pathology

authors： Phull PS,Price AB,Stephens J,Rathbone BJ,Jacyna MR

更新日期：1996-05-01 00:00:00

abstract：:A case of extramedullary myeloblastic transformation of chronic myeloid leukaemia is reported. This was characterised by an unusual clinical and haematological course and showed a unique cytogenetic pattern. ...

journal_title：Journal of clinical pathology

authors： Flanagan NG,Harrison CJ,Harry DS,Ridway JC

更新日期：1985-07-01 00:00:00

abstract：AIMS:It has been suggested that adenocarcinomas of the lower oesophagus and gastric cardia should be reclassified as oesophagogastric junction (OGJ) cancers. This study aimed to define the frequency of OGJ cancers in a geographically defined population of 4.3 million people. METHODS:All cases of oesophageal and gastri...

journal_title：Journal of clinical pathology

authors： Byrne JP,Mathers JM,Parry JM,Attwood SE,Bancewicz J,Woodman CB

更新日期：2002-03-01 00:00:00

abstract：:Of the first 166 heart and 15 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 162 were investigated for cytomegalovirus (CMV) infection by serological methods. Altogether, 73 (45%) developed CMV infection after transplantation: 30 (18.5%...

journal_title：Journal of clinical pathology

authors： Wreghitt TG,Hakim M,Gray JJ,Kucia S,Wallwork J,English TA

更新日期：1988-06-01 00:00:00

abstract：:Factor VII levels have been measured in 100 patients with liver disease following parenteral vitamin K1 therapy. There was good agreement between specific factor VII measurements and the one-stage prothrombin time apart from six patients with compensated cirrhosis in whom the prothrombin time was prolonged despite the...

journal_title：Journal of clinical pathology

authors： Green G,Poller L,Thomson JM,Dymock IW

更新日期：1976-11-01 00:00:00

abstract：AIMS:To determine the sensitivity and specificity of a multiplex PCR assay for the contemporary identification of major species involved in oral candidiasis, without extraction and purification of DNA from the samples under investigation; and evaluation of this method in comparison with routine phenotypic culture ident...

journal_title：Journal of clinical pathology

authors： Liguori G,Lucariello A,Colella G,De Luca A,Marinelli P

更新日期：2007-09-01 00:00:00

abstract：:A case of IgD myeloma accompanied by diffuse osteosclerosis is reported. A trephine biopsy specimen showed only reticulin fibrosis, but histomorphometric analysis of a full thickness transiliac bone biopsy specimen showed increased trabecular bone mass, with no local deposit of tumour. An excess of bone surfaces were ...

journal_title：Journal of clinical pathology

authors： MacCallum PK,Freemont AJ,Geary CG,Liu Yin JA

更新日期：1988-05-01 00:00:00

abstract：:The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastrit...

journal_title：Journal of clinical pathology

authors： Stolte M,Eidt S

更新日期：1989-12-01 00:00:00

abstract：:Urines from patients with symptoms of urinary tract infection yielded mixed growths of different colony types of Escherichia coli. The different colony types were found to be variants of single infecting strains caused by mutation or by phase action. It is suggested that care should be exercised in the interpretation ...

journal_title：Journal of clinical pathology

authors： Nichols GL

更新日期：1975-09-01 00:00:00

abstract：:Guinea-pigs, rats, dogs, rabbits, monkeys, sheep, and goats were screened for G-6PD activity in erythrocytes by the methaemoglobin reduction test, the brilliant cresyl blue decolorization test, and the spectrophotometric determination of the NADPH generation rate. Guinea-pigs, rats, dogs, rabbits, and monkeys were fou...

journal_title：Journal of clinical pathology

authors： Cheun LH

更新日期：1966-11-01 00:00:00

abstract：AIMS:To describe characteristics of a series of people accidentally and deliberately killed by air powered weapons. METHODS:Five cases of fatal airgun injury were identified by forensic pathologists and histopathologists. The circumstances surrounding the case, radiological examination, and pathological findings are d...

journal_title：Journal of clinical pathology

authors： Milroy CM,Clark JC,Carter N,Rutty G,Rooney N

更新日期：1998-07-01 00:00:00

abstract：:In this necropsy review of 37 cases of acute pancreatitis, evidence is presented that there are at least two different initiating mechanisms in acute necrotising pancreatitis in man. Firstly, there is primary duct inflammation, with subsequent inflammation and necrosis of the pancreatic parenchyma surrounding the excr...

journal_title：Journal of clinical pathology

authors： Foulis AK

更新日期：1980-12-01 00:00:00

abstract：AIMS:The JAK2 V617F mutation is highly recurrent in many of the myeloproliferative neoplasms, a molecular variant that can be easily detected using sensitive and minimally invasive techniques. Given the ease of JAK2 V617F testing, this test may be improperly requested for the purposes of patient 'screening' and to opti...

journal_title：Journal of clinical pathology

authors： Mahe E,Pedersen KM,Çolak Y,Bojesen SE,Lynch T,Sinclair G,Khan F,Shabani-Rad MT

更新日期：2019-02-01 00:00:00

abstract：:Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years and there is growing evidence from validation studies that WSI is comparable to glass slides for histopathology diagnosis, although with some limitations, which can be appropriately minimised. Whether the...

journal_title：Journal of clinical pathology

authors： Cheng CL,Tan PH

更新日期：2017-05-01 00:00:00

abstract：:We present the pathological findings in a case of acquired immunodeficiency syndrome (AIDS) in a patient with no known risk factor. Postmortem examination showed klebsiella lung abscess, generalised cytomegalovirus infection, cerebral toxoplasmosis, and a primary cerebral lymphoma. An additional feature was the presen...

journal_title：Journal of clinical pathology

authors： Burt AD,Scott G,Shiach CR,Isles CG

更新日期：1984-04-01 00:00:00

abstract：:This review deals with difficulties of diagnosis in cutaneous malignant melanoma encountered by histopathologists of variable seniority and is based on referred material at The Royal Marsden Hospital over a 20-year period and on the experience of more than two-and-a-half thousand cases referred to The World Health Org...

journal_title：Journal of clinical pathology

authors： Levene A

更新日期：1980-02-01 00:00:00

abstract：:A technique is described for obtaining samples of bladder epithelium using soluble swabs. Changes indicating neoplasia were seen in a large proportion of patients with bladder carcinoma. These changes were absent in the non-neoplastic control cases. The method provided tissue similar to that obtained by biopsy and sur...

journal_title：Journal of clinical pathology

authors： Trott PA,Williams G,Attridge PW

更新日期：1969-11-01 00:00:00

abstract：AIM:To investigate the natural history of patients with non-alcoholic steatohepatitis by means of a prospective histological study. METHODS:One thousand five hundred and seventy one patients underwent liver biopsy at the Western Infirmary in Glasgow during the 10 year period 1985 to 1994. All biopsies were reported by...

journal_title：Journal of clinical pathology

authors： Evans CD,Oien KA,MacSween RN,Mills PR

更新日期：2002-09-01 00:00:00