Quantitation of intraepithelial lymphocytes in human duodenum: what is normal?

abstract：AIMS:Immunohistochemical stains have greatly improved the diagnostic accuracy of renal cell carcinoma (RCC) for primary and distant tumours. We evaluate a marker that has recently been incorporated in clinical practice, PAX-8, in primary and metastatic RCCs. METHODS:Two distinct tissue microarrays were used, one consi...

journal_title：Journal of clinical pathology

authors： Barr ML,Jilaveanu LB,Camp RL,Adeniran AJ,Kluger HM,Shuch B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Somatic mutations are important determinants of cancer behaviour and response to therapy. However, molecular testing in this context has a relatively low profile within the clinical community, despite publicity surrounding targeted therapies such as Herceptin. AIMS:As the testing process affects many stakeh...

journal_title：Journal of clinical pathology

authors： Wordsworth S,Buchanan J,Papanicolas I,Taylor J,Frayling I,Tomlinson I

更新日期：2008-06-01 00:00:00

abstract：:Taking a kidney biopsy is not a trivial procedure. The sample is almost invariably smaller than the pathologist would like. Investigation usually requires division into even smaller samples to permit the application of specialist techniques. In some cases the biopsy is taken not for diagnosis, but to assess the extent...

journal_title：Journal of clinical pathology

authors： Furness PN

更新日期：2000-06-01 00:00:00

abstract：:A 45-year-old man is described in whom there is currently ERCP and histological evidence of primary sclerosing cholangitis (PSC). A liver biopsy obtained 29 years ago shows similar histological features confirming that he had PSC at that time. This case indicates that PSC may follow a relatively benign course. ...

journal_title：Journal of clinical pathology

authors： Goudie BM,Birnie GG,Watkinson G,MacSween RN

更新日期：1983-11-01 00:00:00

abstract：:Electron microscopy od duodenal mucosa from children with acute non-bacterial enteritis has shown virus particles in epithelial cells. Indirect immunofluorescent techniques applied to the same tissue showed virus antigen localized in the cytoplasm of epithelial cells of the villi. Specific IgM antibody was present in ...

journal_title：Journal of clinical pathology

authors： Davidson GP,Goller I,Bishop RF,Townley RR,Holmes IH,Ruck BJ

更新日期：1975-04-01 00:00:00

abstract：AIMS:To investigate the histopathological features of the synovial lining of the knee following implantation of an artificial cruciate ligament. METHODS:Eighty two patients underwent anterior cruciate ligament reconstruction for chronic, symptomatic instability of the knee. The cruciate ligament was reconstructed with...

journal_title：Journal of clinical pathology

authors： Barry M,Thomas SM,Rees A,Shafighian B,Mowbray MA

更新日期：1995-06-01 00:00:00

abstract：AIMS:To compare the expression of immunohistochemical variables between benign and malignant components of malignant peripheral nerve sheath tumour (MPNST) arising within neurofibroma. METHODS:Eight cases of MPNST arising within a neurofibroma, associated with neurofibromatosis type 1 (NF1), were studied. The areas of...

journal_title：Journal of clinical pathology

authors： Watanabe T,Oda Y,Tamiya S,Masuda K,Tsuneyoshi M

更新日期：2001-08-01 00:00:00

abstract：:Non-Hodgkin's lymphoma is not commonly a familial condition. This is believed to be the first two cases of primary pancreatic lymphoma within a single family. The two cases, a brother and sister, both presented in their 60s and were diagnosed histologically as having high grade B cell lymphoma affecting the pancreas, ...

journal_title：Journal of clinical pathology

authors： James JA,Milligan DW,Morgan GJ,Crocker J

更新日期：1998-01-01 00:00:00

abstract：AIMS:To investigate whether cholesterol and lactate dehydrogenase (LDH) measurements in fluids are more sensitive and specific markers for differentiating between exudates and transudates, as confirmed clinically, than the measurement of fluid total protein concentrations alone. PATIENTS/METHODS:Serum, pleural fluid, ...

journal_title：Journal of clinical pathology

authors： Paramothayan NS,Barron J

更新日期：2002-01-01 00:00:00

abstract：:The finding of raised growth hormone concentrations in patients with secondary malignancy in the liver is reported. These concentrations were significantly higher than those found in patients with primary malignancy only or in those with non-hepatic secondaries. A wide range of malignancies was investigated and the hi...

journal_title：Journal of clinical pathology

authors： Andrews GS

更新日期：1983-08-01 00:00:00

abstract：:In a case of atypical mucin-producing bronchial carcinoid in a 40-year-old man covert metastases were present at the time of lobectomy and were revealed at necropsy--a feature highlighting the malignant potential of the atypical carcinoid. ...

journal_title：Journal of clinical pathology

authors： Sweeney EC,Cooney T

更新日期：1978-12-01 00:00:00

abstract：:Five hundred and seven strains of bacteria isolated from the urine of patients with significant bacteriuria (more than 10(8) colony-forming units per litre) were tested for sensitivity to co-trimoxazole by the agar diffusion technique. Each organism was tested with a combined disk containing trimethoprim and sulphamet...

journal_title：Journal of clinical pathology

authors： Amyes SG,Telfer Brunton WA

更新日期：1981-02-01 00:00:00

abstract：:Bone marrow aspirates and biopsy specimens were taken at diagnosis from 51 patients with acute myeloid leukaemia (AML). The diagnosis was based on morphological and cytochemical analyses, and the leukaemias were classified by FAB criteria. A considerable difference was observed between the results of bone marrow aspir...

journal_title：Journal of clinical pathology

authors： Islam A,Frisch B,Henderson ES

更新日期：1989-03-01 00:00:00

abstract：:A family with hypobetalipoproteinaemia was studied to examine the Lp(a) lipoprotein, lipoprotein cholesterol, and triglyceride composition of the serum lipids. Lp(a) lipoprotein was measured by immunoassay. Serum lipoproteins were separated by ultracentrifugation. Cholesterol and triglycerides were measured using stan...

journal_title：Journal of clinical pathology

authors： Crook M,Swaminathan R

更新日期：1995-06-01 00:00:00

abstract：AIMS:Meticillin-resistant Staphylococcus aureus (MRSA) strains isolated in Tawam Hospital, a tertiary care hospital in the United Arab Emirates, were examined in order to understand the reasons for a doubling of its incidence between 2003 and 2008 while maintaining the same infection control measures. METHODS:All cons...

journal_title：Journal of clinical pathology

authors： Sonnevend Á,Blair I,Alkaabi M,Jumaa P,Al Haj M,Ghazawi A,Akawi N,Jouhar FS,Hamadeh MB,Pál T

更新日期：2012-02-01 00:00:00

abstract：:Neoplastic and non-neoplastic oxyphil cells in thyroid disorders were investigated for enzyme and synthetic activity, ultrastructural features, and immune complex deposition. A reduced but definite content of thyroglobuliin and similar enzyme profiles and ultrastructural features in all types of oxyphill change were f...

journal_title：Journal of clinical pathology

authors： Kendall CH,McCluskey E,Meagles JN

更新日期：1986-08-01 00:00:00

abstract：AIMS:Soft tissue tumours are a heterogeneous group of neoplasms that can arise at almost every anatomical site. As they often show similar clinical and radiological findings, histology is the definitive diagnostic method and it is crucial that the surgical pathology report contains accurate, useful information for mana...

journal_title：Journal of clinical pathology

authors： Shah C,Wang J,Mubako T,Fisher C,Thway K

更新日期：2016-09-01 00:00:00

abstract：:A patient with hyperparathyroidism due to a parathyroid adenoma was found to have metastatic medullary carcinoma in lymph nodes close to the thyroid gland. The finding of normal calcitonin and parathormone concentrations after removal of the adenoma suggested that the parathyroid lesion was not the result of the hypoc...

journal_title：Journal of clinical pathology

authors： MacGillivray JB,Anderson CJ

更新日期：1971-12-01 00:00:00

abstract：:The clinical and pathological findings in 23 patients with ischaemic lesions of the alimentary tract (ischaemic enterocolitis) are described. These are compared with findings in 13 patients with occlusive thrombosis of the superior mesenteric artery. The pathological features distinguishing the two conditions are disc...

journal_title：Journal of clinical pathology

authors： McDonald GS,Hourihane DO

更新日期：1972-02-01 00:00:00

abstract：:A 45-year-old female patient underwent right hemihepatectomy for metastatic rectal adenocarcinoma. Preoperative imaging demonstrated an area of focal nodular hyperplasia (FNH) in segment VIII and metastatic carcinoma in segment VI of the liver. Gross and microscopic examination of the former lesion showed features typ...

journal_title：Journal of clinical pathology

authors： Nisar PJ,Zaitoun AM,Damera A,Hodi Z,Tierney GM,Beckingham IJ

更新日期：2002-12-01 00:00:00

abstract：:Serum lysozyme levels were determined by a turbidometric method using egg white lysozyme as standard in 100 patients with Crohn's disease, 86 with ulcerative colitis, 31 with coeliac disease, and in 38 normal control subjects. Though the levels in Crohn's disease were significantly higher than those in ulcerative coli...

journal_title：Journal of clinical pathology

authors： Mallas E,Terry JM,Asquith P,Cooke WT

更新日期：1976-07-01 00:00:00

abstract：:The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on ...

journal_title：Journal of clinical pathology

authors： NOBLE WC,WILLIAMS RE,JEVONS MP,SHOOTER RA

更新日期：1964-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) is a recognised cause of morbidity and mortality in immunocompromised individuals. This review will concentrate on recent advances in the understanding of the complex interplay between the host and parasite and the pathological consequences of perturbation of the host immune system. The classic v...

journal_title：Journal of clinical pathology

authors： Emery VC

更新日期：2001-02-01 00:00:00

abstract：:The significance of seroconversion as detected by an ELISA screening test for hepatitis C virus (HCV) antibody with a negative supplemental/confirmatory recombinant immunoblot assay (RIBA) result was investigated. Of 118,220 established West Midlands blood donors with at least one negative HCV antibody screen, 43 had ...

journal_title：Journal of clinical pathology

authors： Atrah HI,Ahmed MM

更新日期：1996-03-01 00:00:00

abstract：:Gastrointestinal (GI) symptoms including abdominal pain, bloating and diarrhoea are a relatively common reason for consulting a physician. They may be due to inflammatory bowel disease (inflammatory bowel disease; Crohn's disease, ulcerative colitis and indeterminate colitis), malignancy (colorectal cancer), infectiou...

journal_title：Journal of clinical pathology

authors： Sherwood RA

更新日期：2012-11-01 00:00:00

abstract：AIMS:To assess the effect of cellulosic dialysis membranes on the production of complement degradation products to determine to the role of the classical pathway. METHOD:Complement activation was studied in 33 patients during a single haemodialysis session using cellulosic membranes. Pre- and post-dialysis plasma EDTA...

journal_title：Journal of clinical pathology

authors： Innes A,Farrell AM,Burden RP,Morgan AG,Powell RJ

更新日期：1994-02-01 00:00:00

abstract：:Immunoreactive plasminogen activators were studied in tissue sections using a peroxidase method and monospecific antibodies to tissue plasminogen activator produced by a melanoma. Tissue plasminogen activator reactivity was found in skin melanomas and in endothelial and smooth muscle cells of arteries and veins. Vesse...

journal_title：Journal of clinical pathology

authors： Larsson A,Astedt B

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Autoreactive humoral and cellular immune responses may be involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC). Certain human leucocyte antigens (HLA) could also be linked to the development of IDC. AIM:To determine whether various markers of autoimmunity are present in the final phase of...

journal_title：Journal of clinical pathology

authors： de Leeuw N,Melchers WJ,Ruiter DJ,Caforio AL,Balk AH,de Jonge N,Galama JM

更新日期：1999-10-01 00:00:00

abstract：:Leucocyte ascorbate (LA) and serum ascorbate (SA) were measured in patients who had sustained an acute cerebrovascular accident. There was a significant fall in LA and Sa within 24 hours of the incident and this persisted for several weeks. The "stress" of the event resulted in a rise in serum cortisol concentration a...

journal_title：Journal of clinical pathology

authors： Hume R,Vallance BD,Muir MM

更新日期：1982-02-01 00:00:00

abstract：AIMS:Our laboratory is a centralised centre receiving routine non-small cell lung cancer (NSCLC) samples for programmed death ligand-1 (PD-L1) immunohistochemical (IHC) evaluation. Since literature data are not concordant here we review our clinical records to assess the rate of PD-L1 positive and negative NSCLC cases ...

journal_title：Journal of clinical pathology

authors： Vigliar E,Malapelle U,Iaccarino A,Acanfora G,Pisapia P,Clery E,De Luca C,Bellevicine C,Troncone G

更新日期：2019-06-01 00:00:00