Immunofluorescence in duodenal mucosa of children with acute enteritis due to a new virus.

abstract：:Neoplastic and non-neoplastic oxyphil cells in thyroid disorders were investigated for enzyme and synthetic activity, ultrastructural features, and immune complex deposition. A reduced but definite content of thyroglobuliin and similar enzyme profiles and ultrastructural features in all types of oxyphill change were f...

journal_title：Journal of clinical pathology

authors： Kendall CH,McCluskey E,Meagles JN

更新日期：1986-08-01 00:00:00

abstract：AIMS:To investigate treatment with glycerol/washing as a potential substitute for freeze-thawing in the production of leucocyte depleted red cell concentrates for patients with a history of non-haemolytic reactions following transfusion. METHODS:The standard procedure of treatment with glycerol/-80 degrees C freezing/...

journal_title：Journal of clinical pathology

authors： Farrugia A,Shea N,Knowles S,Holdsworth R,Piouronowski H,Portbury D,Romeo A

更新日期：1993-08-01 00:00:00

abstract：:A sensitive gas chromatography-mass spectrometric method was used to measure the generation in whole blood of leukotriene B4 (LTB4), a potent stimulator of neutrophil chemotaxis, in eight patients with chronic granulocytic leukaemia (CGL) and 12 healthy controls. LTB4 was detectable in unstimulated samples from all th...

journal_title：Journal of clinical pathology

authors： Reilly IA,Knapp HR,Fitzgerald GA

更新日期：1988-11-01 00:00:00

abstract：:Concentration of factor VIII from fresh plasma by cryoprecipitation remains the basis for preparation of products used to treat haemophilia A. This paper describes the preparation of a factor VIII concentrate from small plasma pools in transfusion centres with drying facilities. The dried concentrate from one litre of...

journal_title：Journal of clinical pathology

authors： Millgan G,Graham R,Hanratty S,Muir W,Mitchell R

更新日期：1981-10-01 00:00:00

abstract：:A quantitative histological analysis of the major salivary glands was carried out at necropsy in 28 alcoholics and in a series of age and sex matched controls. The findings were related to the different types of histologically diagnosed liver disease present. Significant quantitative changes of salivary gland structur...

journal_title：Journal of clinical pathology

authors： Scott J,Burns J,Flower EA

更新日期：1988-08-01 00:00:00

abstract：:Cryostat sections from 160 rectal suction biopsies were stained for cholinesterases by the method of Karnovsky and Roots (1964) in an attempt to facilitate the diagnosis of Hirschsprung's disease. The method proved at least as reliable as experienced assessment of paraffin haematoxylin-eosin sections, and appeared to ...

journal_title：Journal of clinical pathology

authors： Trigg PH,Belin R,Haberkorn S,Long WJ,Nixon HH,Plaschkes J,Spitz L,Willital GH

更新日期：1974-03-01 00:00:00

abstract：:The Fisher Hem-Alyzer is a multitest sequential discrete analyser with automatic printout of digitized results on paper tape. The instrument is well designed, soundly constructed, and reliable in routine use. Cross contamination from the sampler probe or between the cuvettes is minimal. Accuracy and precision are both...

journal_title：Journal of clinical pathology

authors： Lappin TR,Lamont A,Nelson MG

更新日期：1970-02-01 00:00:00

abstract：AIM:To establish whether infection with Epstein-Barr virus (EBV) contributed to the development of coronary artery lesions in a six year old child with an aneurysm and stenoses of the coronary arteries and suspected Kawasaki disease. METHODS:Postmortem paraffin wax sections of the coronary artery and myocardium were e...

journal_title：Journal of clinical pathology

authors： Culora GA,Moore IE

更新日期：1997-02-01 00:00:00

abstract：:Morphometric techniques were applied to cytocentrifuge smears from 27 patients with histologically confirmed follicular non-Hodgkin's lymphoma to determine the usefulness of this method in diagnosis. Analysis of quantitative data confirmed that most subtypes were classified correctly on the basis of the proportion of ...

journal_title：Journal of clinical pathology

authors： Stevens MW,Crowley KS,Fazzalari NL,Woods AE

更新日期：1988-04-01 00:00:00

abstract：AIMS:An increase in the proliferative state of the gastric epithelium has been attributed to infection with Helicobacter pylori. In order to obtain a more precise estimate of the magnitude of this change, the proliferative state of 17 cases of florid H pylori associated follicular gastritis was examined using the antib...

journal_title：Journal of clinical pathology

authors： Havard TJ,Sarsfield P,Wotherspoon AC,Steer HW

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:A twofold increased risk for breast cancer has been reported recently for women with late onset diabetes. Most studies showed that there were differences in serum concentrations of insulin-like growth factors and related proteins between women with and without diabetes who have breast cancer. This study...

journal_title：Journal of clinical pathology

authors： Nardon E,Buda I,Stanta G,Buratti E,Fonda M,Cattin L

更新日期：2003-08-01 00:00:00

abstract：:An immunohistochemical study of the tissue CEA content of 82 epithelial neoplasms of the ovary has shown that mucinous tumours contain more of this substance than do their serous counterparts; otherwise a knowledge of tissue CEA content appears to be of little value in the differential histological diagnosis of this g...

journal_title：Journal of clinical pathology

authors： Heald J,Buckley CH,Fox H

更新日期：1979-09-01 00:00:00

abstract：:Advanced non-small cell lung cancer samples are tested for epidermal growth factor receptor (EGFR) gene mutations. Their detection by direct sequencing is time-consuming. Conversely, the length analysis of fluorescently labelled PCR products is easier. To avoid labelled primers and the automated capillary electrophore...

journal_title：Journal of clinical pathology

authors： Malapelle U,Russo S,Pepe F,Sgariglia R,De Luca C,Bellevicine C,Pallante P,Troncone G

更新日期：2013-11-01 00:00:00

abstract：:A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discusse...

journal_title：Journal of clinical pathology

authors： Burns GF,Cawley JC,Flemans RJ,Higgy KE,Worman CP,Barker CR,Roberts BE,Hayhoe FG

更新日期：1977-10-01 00:00:00

abstract：:Serum alanine aminotransferase (ALT) and gamma-glutamyltransferase (gamma-GT) activities were measured in over 2000 north London blood donors. The results were compared with those from the United States. The percentage of the total donor population with ALT activities above 40 IU/l in 1986 was greater than that found ...

journal_title：Journal of clinical pathology

authors： Mijovic V,Contreras M,Barbara J

更新日期：1987-11-01 00:00:00

abstract：:The use of liquid media to detect the production of beta-lactamase by beta-lactamase producing organisms has been compared with the conventional method of inoculation on to agar media. Pharyngeal cultures were obtained from 162 children treated with penicillin for acute tonsillitis. beta-lactamase producing organisms ...

journal_title：Journal of clinical pathology

authors： Brook I,Gober AE

更新日期：1984-12-01 00:00:00

abstract：:Mixed lymphocyte reactions (MLRs) were measured in 25 HLA-A, B and DR compatible sibling bone marrow transplants. Only four of 25 MLRs were positive and in these the low reactivity was of doubtful clinical importance. There was no correlation between MLR and the subsequent development or severity of graft versus host ...

journal_title：Journal of clinical pathology

authors： Lim SH,Patton WN,Jobson S,Gentle TA,Baynham M,Franklin IM,Broughton BJ

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:A genetic component to the development of chronic fatigue syndrome (CFS) has been proposed, and a possible association between human leucocyte antigen (HLA) class II antigens and chronic fatigue immune dysfunction has been shown in some, but not all, studies. AIMS:To investigate the role of HLA class II ant...

journal_title：Journal of clinical pathology

authors： Smith J,Fritz EL,Kerr JR,Cleare AJ,Wessely S,Mattey DL

更新日期：2005-08-01 00:00:00

abstract：AIM:To determine whether sampling the anterior and posterior cervical lips in hysterectomy specimens provides the best opportunity for detecting unsuspected cervical intraepithelial neoplasia (CIN). METHODS:The frequency with which CIN was identified at a range of positions on the anterior and posterior lips and left ...

journal_title：Journal of clinical pathology

authors： Heatley M

更新日期：1995-04-01 00:00:00

abstract：:The effect of acute hypoglycaemia on platelet function was examined in patients undergoing an insulin stress test. Enhanced platelet aggregation was observed in all cases but platelet count, platelet adenine nucleotides, and the plasma level of von Willebrand factor were unchanged overall. The onset of the hypoglycaem...

journal_title：Journal of clinical pathology

authors： Hutton RA,Mikhailidis D,Dormandy KM,Ginsburg J

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that minichromosome maintenance (MCM) proteins (Mcm2-7) may be useful proliferation markers in dysplasia and cancer in various tissues. AIMS:To investigate the use of Mcm7 as a proliferation marker in 79 lymph node negative prostate cancers and compare it with Ki-67, a commonly use...

journal_title：Journal of clinical pathology

authors： Padmanabhan V,Callas P,Philips G,Trainer TD,Beatty BG

更新日期：2004-10-01 00:00:00

abstract：:In 12 normal subjects plasma calcium and phosphorus concentrations were estimated during a normal working day. In the individual subjects fluctuations from the fasting values occurred during the period of study, but at no time during that period did the mean values differ significantly from the fasting plasma calcium ...

journal_title：Journal of clinical pathology

authors： Wills MR

更新日期：1970-12-01 00:00:00

abstract：BACKGROUND:Receptor activator of nuclear factor kappabeta ligand (RANKL) has an important role in bone remodelling, and tumour necrosis factor related, apoptosis inducing ligand (TRAIL) can induce apoptosis in cancer cells. Their functions are linked by their interactions with osteoprotegerin (OPG). OBJECTIVE:To inves...

journal_title：Journal of clinical pathology

authors： Cross SS,Harrison RF,Balasubramanian SP,Lippitt JM,Evans CA,Reed MW,Holen I

更新日期：2006-07-01 00:00:00

abstract：:The pathological findings of an intradural and extramedullary cyst in the mid cervical spinal canal are described in a 55 year old woman who presented with a short history of pain and paraesthesia of the right arm. Intradural well defined solitary cystic lesions in the spinal canal are uncommon, their pathogenesis is ...

journal_title：Journal of clinical pathology

authors： Wilkinson N,Reid H,Hughes D

更新日期：1992-11-01 00:00:00

abstract：AIMS:To isolate RNA and DNA simultaneously from formalin fixed paraffin wax embedded tissue to assess the clonality of enteropathy associated T cell lymphomas and to analyse it in detail by a non-radioactive method of T cell receptor complementarity determining region 3 (CDR3) spectratyping. METHODS:DNA and RNA were i...

journal_title：Journal of clinical pathology

authors： O'Shea U,Wyatt JI,Howdle PD

更新日期：1997-10-01 00:00:00

abstract：:The titre of antibodies to Toxoplasma gondii was compared in 1985 sera by use of an indirect haemagglutination test (ToxHA test--Wellcome Reagents Ltd) and the dye test. Sera from 42 patients with clinical or serological indications of recent toxoplasmosis were also examined to determine if the ToxHA test would be of ...

journal_title：Journal of clinical pathology

authors： Balfour AH,Bridges JB,Harford JP

更新日期：1980-07-01 00:00:00

abstract：:Urines from patients with symptoms of urinary tract infection yielded mixed growths of different colony types of Escherichia coli. The different colony types were found to be variants of single infecting strains caused by mutation or by phase action. It is suggested that care should be exercised in the interpretation ...

journal_title：Journal of clinical pathology

authors： Nichols GL

更新日期：1975-09-01 00:00:00

abstract：UNLABELLED:Encapsulated papillary carcinoma (EPC) of the breast is a distinct histological subtype characterised by malignant epithelial proliferation supported by fibrovascular stalks. Although EPC typically lacks myoepithelial cells, it shows indolent clinical course. The classification of EPC as an in situ, or invas...

journal_title：Journal of clinical pathology

authors： Rakha EA,Tun M,Junainah E,Ellis IO,Green A

更新日期：2012-08-01 00:00:00

abstract：AIMS:As part of the UK antimicrobial resistance strategy and action plan, the Public Health Laboratory Service (PHLS) is required to collect antibiotic susceptibility data so that resistance trends and patterns can be monitored. Most laboratories report urine Gram negative isolates, as "coliforms" according to morpholo...

journal_title：Journal of clinical pathology

authors： Fallon D,Andrews N,Frodsham D,Gee B,Howe S,Iliffe A,Nye KJ,Warren RE

更新日期：2002-07-01 00:00:00

abstract：:A case of Cryptococcus neoformans meningitis is described in an HIV negative patient with undiagnosed systemic sarcoidosis. The patient presented with signs of meningitis together with generalised lymphadenopathy and hepatosplenomegaly. Cryptococcal meningitis was diagnosed on lumbar puncture. She was treated with int...

journal_title：Journal of clinical pathology

authors： Botha RJ,Wessels E

更新日期：1999-12-01 00:00:00