DNA replication regulation protein Mcm7 as a marker of proliferation in prostate cancer.

abstract：:In two families with severe sex-linked muscular dystrophy, high levels of alpha-hydroxybutyrate dehydrogenase (HBD), lactate dehydrogenase (LD), aspartate transaminase (AspT), aldolase, and creatine phosphokinase (CPK) were found in the sera of three young affected males. In both families the mother had a raised level...

journal_title：Journal of clinical pathology

authors： Johnston HA,Wilkinson JH,Withycombe WA,Raymond S

更新日期：1966-05-01 00:00:00

abstract：:Platelet concentrates were prepared for in vitro storage in either Fenwal PL-732 or Cutter CLX platelet packs. The units were stored at 22 degrees C for seven days with either horizontal or tumbler agitation. Measurement of pH, hypotonic shock response and serotonin uptake indicated in vitro viability was well maintai...

journal_title：Journal of clinical pathology

authors： Taylor MA,Tandy NP,Fraser ID

更新日期：1983-12-01 00:00:00

abstract：AIMS:The aim of this study is to explore DNA hypermethylation analysis in sputum and exhaled breath analysis for their complementary, non-invasive diagnostic capacity in lung cancer. METHODS:Sputum samples and exhaled breath were prospectively collected from 20 lung cancer patients and 31 COPD controls (Set 1). An add...

journal_title：Journal of clinical pathology

authors： Hubers AJ,Brinkman P,Boksem RJ,Rhodius RJ,Witte BI,Zwinderman AH,Heideman DA,Duin S,Koning R,Steenbergen RD,Snijders PJ,Smit EF,Sterk PJ,Thunnissen E

更新日期：2014-08-01 00:00:00

abstract：:Apocrine morphology is a common phenomenon encountered in everyday breast pathology practice, and is defined as cuboidal or columnar cells exhibiting abundant eosinophilic granular cytoplasm, prominent apical granules, a low nuclear-cytoplasmic ratio, and round nuclei with pale chromatin and prominent nucleoli. Apocri...

journal_title：Journal of clinical pathology

authors： D'Arcy C,Quinn C

更新日期：2019-01-01 00:00:00

abstract：:An indirect immunoperoxidase technique has been used for visualisation of cellular immunoglobulins in chronic lymphocytic leukaemia. Baker's formol calcium was used as fixative. Monoclonal light and heavy chain patterns were demonstrated in 24 out of 27 cases. Only one case did not have any demonstrable immunoglobulin...

journal_title：Journal of clinical pathology

authors： Markey GM,McConnell RE,Alexander HD,Morris TC,Robertson JH

更新日期：1983-12-01 00:00:00

abstract：AIMS:In everyday practice, epidermal growth factor receptor (EGFR) testing is centralised in referral laboratories that receive paucicellular cytological specimens. Ideally, EGFR testing should be carried out in the centre where the patient is diagnosed such that the most cellular slide can be selected from in-house co...

journal_title：Journal of clinical pathology

authors： De Luca C,Gragnano G,Pisapia P,Vigliar E,Malapelle U,Bellevicine C,Troncone G

更新日期：2017-04-01 00:00:00

abstract：:Eight strains of Pseudomonas putrefaciens have been received from among 466 strains of Pseudomonas submitted to the Computer Trials Laboratory for identification over the last eight years. Two of the strains of P. putrefaciens from patients with otitis media and otitis externa respectively appear to have played a path...

journal_title：Journal of clinical pathology

authors： Holmes B,Lapage SP,Malnick H

更新日期：1975-02-01 00:00:00

abstract：:DNA typing was requested to investigate a presumptive cancer diagnosis error by confirming whether benign and cancerous prostatic tissue in the same presurgical haematoxylin and eosin stained slide belonged to the same person. After independent histological re-examination of the slide by a pathologist, manual slide di...

journal_title：Journal of clinical pathology

authors： Alonso A,Alves C,Suárez-Mier MP,Albarrán C,Pereira L,Fernández de Simón L,Martín P,García O,Gusmão L,Sancho M,Amorim A

更新日期：2005-01-01 00:00:00

abstract：:During a 12-month period, 40 146 blood donors were tested for the presence of high titre antitetanus antibodies. An attempt has been made to define the most suitable donors, those with antitetanus antibody titres of 4 IU/ml or above, by virtue of titre, sex, location, and length of time since most recent immunisation...

journal_title：Journal of clinical pathology

authors： Wiseman IC,Gascoigne ME

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Friend leukaemia integration-1 (FLI-1) antibody is a useful marker for Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET) and vascular tumours. However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT). AIM:To de...

journal_title：Journal of clinical pathology

authors： Mhawech-Fauceglia P,Herrmann FR,Bshara W,Odunsi K,Terracciano L,Sauter G,Cheney RT,Groth J,Penetrante R,Mhawech-Fauceglia P

更新日期：2007-06-01 00:00:00

abstract：:The activities of phosphohexose isomerase and 6-phosphogluconate dehydrogenase have been studied in the vaginal fluid of women from the gynaecological departments. Women from these departments gave a very high false positive rate, though no cases of carcinoma in situ were not detected by estimating phosphohexose isome...

journal_title：Journal of clinical pathology

authors： Muir GG

更新日期：1966-07-01 00:00:00

abstract：AIMS:To investigate whether increasing the daily baseline of gut calcium can cause a gradual downregulation of the active intestinal transport of calcium via reduced parathyroid hormone (PTH) mediated activation of vitamin D, and to discuss why such a mechanism might prevent calcium oxalate rich stones. To demonstrate ...

journal_title：Journal of clinical pathology

authors： Williams CP,Child DF,Hudson PR,Davies GK,Davies MG,John R,Anandaram PS,De Bolla AR

更新日期：2001-01-01 00:00:00

abstract：AIMS:To develop a strategy for neonatal screening of sickle cell disease (SCD) and effective enrollment of affected neonates in a comprehensive follow-up programme adapted to the socioeconomic conditions, health structures and cultural background of an African setting. METHODS:The strategy implemented at the two large...

journal_title：Journal of clinical pathology

authors： Rahimy MC,Gangbo A,Ahouignan G,Alihonou E

更新日期：2009-01-01 00:00:00

abstract：:Of the first 250 heart and 35 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 217 heart and 33 heart and lung patients were investigated serologically for evidence of Toxoplasma gondii infection. Six patients acquired primary T gondii in...

journal_title：Journal of clinical pathology

authors： Wreghitt TG,Hakim M,Gray JJ,Balfour AH,Stovin PG,Stewart S,Scott J,English TA,Wallwork J

更新日期：1989-02-01 00:00:00

abstract：:A modified nitroblue tetrazolium test (NBT) is described which is suitable for routine application in the haematology or bacteriology laboratory and which provides a rapid aid to the diagnosis of bacterial infection. Hitherto published methods have recommended the use of heparinized whole blood samples for the perform...

journal_title：Journal of clinical pathology

authors： Gordon AM,Rowan RM,Brown T,Carson HG

更新日期：1973-01-01 00:00:00

abstract：AIM:To develop a polymerase chain reaction (PCR) for the specific detection of the C protein gene in strains of group B Streptococcus. METHODS:A single primer pair derived from the nucleotide sequence of the IgA binding beta antigen of the C protein complex permitted the specific amplification of a 592 base pair DNA f...

journal_title：Journal of clinical pathology

authors： Mawn JA,Simpson AJ,Heard SR

更新日期：1993-07-01 00:00:00

abstract：AIMS:The aims of this study were (1) to determine the measurement accuracy of a widely used guaiac faecal occult blood test (gFOBT) compared with an immunochemical faecal occult blood test (iFOBT) during in vitro studies, including their analytical stability over time at ambient temperature and at 4°C; and (2) to compa...

journal_title：Journal of clinical pathology

authors： Lee CS,O'Gorman P,Walsh P,Qasim A,McNamara D,O'Morain CA,Boran GP

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Thyrotropin-secreting adenomas (TSH-As) are rare and, according to the World Health Organization criteria (WHO 2004), a significant proportion of them present features of atypical adenomas at the time of diagnosis. AIMS:To determine the frequency of "atypical adenomas" and the significance of this definitio...

journal_title：Journal of clinical pathology

authors： Marucci G,Faustini-Fustini M,Righi A,Pasquini E,Frank G,Agati R,Foschini MP

更新日期：2009-05-01 00:00:00

abstract：:Neutropenia is a rare complication of Diamond-Blackfan syndrome (congenital hypoplastic anaemia). Three patients are reported: all had neutropenia as well as anaemia, and to investigate the cause of the neutropenia culture of bone marrow for granulocyte-macrophage colony forming cells (GMCFCs) was performed. Two cases...

journal_title：Journal of clinical pathology

authors： Schofield KP,Evans DI

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Venous invasion (VI) is an important prognosis predictor after colorectal carcinoma (CRC) resection, enabling more accurate staging and influencing postoperative management. AIMS:To assess/compare various tissue block types (perpendicular, tangential, across mesentery (AM), from major vessels or lymph nodes...

journal_title：Journal of clinical pathology

authors： Sternberg A,Mizrahi A,Amar M,Groisman G

更新日期：2006-02-01 00:00:00

abstract：:Cryostat sections from 160 rectal suction biopsies were stained for cholinesterases by the method of Karnovsky and Roots (1964) in an attempt to facilitate the diagnosis of Hirschsprung's disease. The method proved at least as reliable as experienced assessment of paraffin haematoxylin-eosin sections, and appeared to ...

journal_title：Journal of clinical pathology

authors： Trigg PH,Belin R,Haberkorn S,Long WJ,Nixon HH,Plaschkes J,Spitz L,Willital GH

更新日期：1974-03-01 00:00:00

abstract：BACKGROUND:Fibrinogen plays a crucial role in the pathophysiology of tumour cell growth, invasion and metastasis. The aim of this study was to evaluate the prognostic significance of pretreatment plasma fibrinogen levels in patients with diffuse large B cell lymphoma (DLBCL) METHODS: Data from 372 patients with DLBCL, ...

journal_title：Journal of clinical pathology

authors： Troppan KT,Melchardt T,Wenzl K,Schlick K,Deutsch A,Bullock MD,Reitz D,Beham-Schmid C,Weiss L,Neureiter D,Tränkenschuh W,Greil R,Neumeister P,Egle A,Pichler M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In primary cutaneous melanoma, the sentinel node (SN) biopsy is an accurate method for the staging of the lymph nodes. Positron emission tomography (PET) has been suggested as a useful alternative. However, the sensitivity of PET may be too low to detect SN metastases, which are often small. AIM:To predict ...

journal_title：Journal of clinical pathology

authors： Mijnhout GS,Hoekstra OS,van Lingen A,van Diest PJ,Adèr HJ,Lammertsma AA,Pijpers R,Meijer S,Teule GJ

更新日期：2003-04-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：:A patient with multiple injuries developed a severe coagulation defect due to a deficiency of vitamin K. None of the usual predisposing factors was present and the patient's diet was very poor. Dietary deficiency of vitamin K and the importance of antibiotic therapy in its production are discussed. ...

journal_title：Journal of clinical pathology

authors： Colvin BT,Lloyd MJ

更新日期：1977-12-01 00:00:00

abstract：:Immunoreactive trypsin (IRT) content in blood spots from 17 cystic fibrosis (CF) children born between 1975-80 were assayed with reagents from two commercial radioimmunoassay kits. The manufacturers' procedures were modified to allow assay of blood spot IRT. Half of the CF samples had a significantly raised IRT conten...

journal_title：Journal of clinical pathology

authors： Ryley HC,Robinson PG,Yamashiro Y,Bradley DM

更新日期：1981-08-01 00:00:00

abstract：AIMS:To investigate the serological cross reaction between legionella and campylobacter using the rapid microagglutination test (RMAT). METHODS:Serum samples from 49 patients with campylobacter infection were tested for legionella antibodies using the indirect fluorescent antibody test (IFAT) and the RMAT. Serum sampl...

journal_title：Journal of clinical pathology

authors： Boswell TC

更新日期：1996-07-01 00:00:00

abstract：:A technique is described for obtaining samples of bladder epithelium using soluble swabs. Changes indicating neoplasia were seen in a large proportion of patients with bladder carcinoma. These changes were absent in the non-neoplastic control cases. The method provided tissue similar to that obtained by biopsy and sur...

journal_title：Journal of clinical pathology

authors： Trott PA,Williams G,Attridge PW

更新日期：1969-11-01 00:00:00

abstract：:Visceral botryomycosis is rare, and documented sites are lung, brain, kidney, liver and prostate. This report describes a rare autopsy case of disseminated visceral botryomycosis, with bulky, grape-like botryomycotic vegetations in the heart, and similar abscesses in the lungs and bone marrow. This is the first such r...

journal_title：Journal of clinical pathology

authors： Gupta K,Das A,Radotra BD,Bhalla A

更新日期：2008-08-01 00:00:00

abstract：:A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in gamma globulin was also noted from the...

journal_title：Journal of clinical pathology

authors： RAWSTRON JR,FARTHING CP

更新日期：1962-03-01 00:00:00