Use of soluble swabs in the diagnosis of bladder neoplasia.

abstract：AIMS:To validate a method of assessment of low hepatic iron concentration based on a biochemical colorimetric assay plus histological scoring. METHODS:The within-day and day to day precision of the iron colorimetric assay was determined on frozen rat liver. The coefficient of variation (CV) of iron measurement in two ...

journal_title：Journal of clinical pathology

authors： Imbert-Bismut F,Charlotte F,Turlin B,Khalil L,Piton A,Brissot P,Le Charpentier Y,Delattre J,Opolon P,Deugnier Y,Poynard T

更新日期：1999-06-01 00:00:00

abstract：:A study has been made by clinical methods and by bio-assay of the effectiveness of a régime for prophylaxis against tetanus. The two principal objects of the method were to ensure that active immunization was offered to all patients who had received antitoxin and to measure the effect of the combined administration of...

journal_title：Journal of clinical pathology

authors： LAURENCE M,HOLT LB,GRAHAM CE,BONNEY GL

更新日期：1965-01-01 00:00:00

abstract：:Specimens of muscle were obtained from non-suppurating lesions of nine patients with tropical myositis. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure. Perimysial cells were also degenerate. Sections from two out of nine patients revealed intracellular vesicles,...

journal_title：Journal of clinical pathology

authors： Taylor JF,Fluck D,Fluck D

更新日期：1976-12-01 00:00:00

abstract：:Antibodies against alpha smooth muscle actin (ASMA) and S100 protein were applied to paraffin wax embedded sections from 40 salivary gland tumours and seven normal salivary glands. The results indicate that ASMA is useful in the diagnosis of epithelial-myoepithelial carcinoma, but is otherwise only of limited use in d...

journal_title：Journal of clinical pathology

authors： Jones H,Moshtael F,Simpson RH

更新日期：1992-10-01 00:00:00

abstract：AIMS:We aimed to study epidermal growth factor receptor (EGFR) expression in surgically resected pancreatic ductal adenocarcinomas (PDACs) by immunohistochemistry and their relationship to clinicopathological features, cell proliferation and cell adhesion protein expression. METHODS:A total of 99 PDACs were analysed o...

journal_title：Journal of clinical pathology

authors： Handra-Luca A,Hammel P,Sauvanet A,Lesty C,Ruszniewski P,Couvelard A

更新日期：2014-04-01 00:00:00

abstract：:A method is described for assessing thyroid status using Sephadex column chromatography of serum samples with added (125)I triiodothyronine. The method is simple and inexpensive. It gave a correct diagnostic result in 97% of 258 euthyroid, 90% of 80 hyperthyroid, 78% of 59 hypothyroid, and 67% of 50 euthyroid, ill pat...

journal_title：Journal of clinical pathology

authors： Gimlette TM

更新日期：1967-03-01 00:00:00

abstract：:Malignant histiocytosis (histiocytic medullary reticulosis) in a 45-year-old white man is described. Unusual features were presentation as a surgical emergency with signs of obstruction and peritonitis due to an ileal tumour and extensive spindle cell differentiation. Problems in the differential diagnosis of malignan...

journal_title：Journal of clinical pathology

authors： Macgillivray JB,Duthie JS

更新日期：1977-02-01 00:00:00

abstract：:Twenty-two known strains of the Bacteroides fragilis group of organisms and 67 clinical specimens from a variety of sites were examined by fluorescent antibody test (IFA) using two different antisera fro the rapid detection of B fragilis group of organisms. A previously reported Barts' pooled antisera was compared wit...

journal_title：Journal of clinical pathology

authors： Wills A,Taylor E,Pantosti A,Phillips I,Tabaqchali S

更新日期：1982-03-01 00:00:00

abstract：:This paper describes the value in diagnosis and the clinical implications of the detection of pneumococcal antigen in patients with lobar pneumonia. Ninety-eight patients with lobar pneumonia were investigated. Pneumococcal antigen was detected by counter-current immunoelectrophoresis in the sputum of 79% of patients ...

journal_title：Journal of clinical pathology

authors： Tugwell P,Greenwood BM

更新日期：1975-02-01 00:00:00

abstract：:Human papillomavirus antigen was found in 39 (16%) of 253 colposcopic biopsies from a group of women at high risk for cervical cancer who had been examined in the early 1970s. Immunohistochemical evidence of papillomavirus infection was found in 20 (30%) of 67 cervical intraepithelial neoplasia lesions infected with w...

journal_title：Journal of clinical pathology

authors： Singer A,Wilters J,Walker P,Jenkins D,Slavin G,Cowdell H,To A,Husain O

更新日期：1985-08-01 00:00:00

abstract：AIM:To analyse whether the mean nuclear area of the 10 largest nuclei (MNA-10), the mitotic activity index (MAI), and Ki-67 immunoquantitative features have additional value to discriminate different grades of T(A,1) transitional cell carcinoma (TCC) of the urinary bladder. MATERIALS/METHODS:One hundred and fifty of 2...

journal_title：Journal of clinical pathology

authors： Bol MG,Baak JP,de Bruin PC,Rep S,Marx W,Bos S,Kisman O

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Inflammatory cells contribute to the growth and spread of human malignancies by producing molecules that enhance tumour invasiveness. AIMS:To characterise the inflammatory infiltrate in pancreatic ductal adenocarcinoma and to analyse its contribution to angiogenesis and its prognostic relevance. METHODS:Im...

journal_title：Journal of clinical pathology

authors： Esposito I,Menicagli M,Funel N,Bergmann F,Boggi U,Mosca F,Bevilacqua G,Campani D

更新日期：2004-06-01 00:00:00

abstract：:The effect of the new beta-lactam antibiotic FL 1060 on urinary tract pathogens, of which 71 were sensitive to and 100 resistant to ampicillin, is presented here. When tested by conventional methods FL 1060 was found to be highly active against ampicillin-sensitive strains of E. coli but phenotypically resistant varia...

journal_title：Journal of clinical pathology

authors： Greenwood D,Brooks HL,Gargan R,O'Grady F

更新日期：1974-03-01 00:00:00

abstract：:Fluorigenic substrates prepared from 4-methylumbelliferone provide a simple, convenient method for detecting and assaying group-specific hydrolase activity in small quantities of whole mycobacteria. Physico-chemical properties of the enzymes such as pH dependence and heat stability may also be studied. A technique is ...

journal_title：Journal of clinical pathology

authors： Grange JM

更新日期：1978-04-01 00:00:00

abstract：:A rapid and simple enzyme linked immunosorbent assay (ELISA) for the detection of specific IgG against Toxoplasma gondii was compared with the dye test on 533 serum samples. In general, results were comparable but not with sera that contained high concentrations of toxoplasma specific IgM or that had been heated at 56...

journal_title：Journal of clinical pathology

authors： Francis JM,Payne RA,Joynson DH

更新日期：1988-07-01 00:00:00

abstract：:The results of the measurement of vitamin B(12) absorption by counting the radioactivity of 5 ml. serum obtained eight to 10 hours after the ingestion of an oral dose of 0.5 mug. vitamin B(12) labelled with 0.5 muc. (57)Co are compared with those obtained with the urinary excretion (Schilling) test. Inadequate urine c...

journal_title：Journal of clinical pathology

authors： Forshaw J,Harwood L

更新日期：1966-11-01 00:00:00

abstract：:The clinical and pathological features of a case of malakoplakia of the adrenal gland occurring in a woman with Escherichia coli infection are described. This lesion mimicked a neoplasm, the true diagnosis only being revealed by histological examination. The light and electron microscopic features are described and it...

journal_title：Journal of clinical pathology

authors： Benjamin E,Fox H

更新日期：1981-06-01 00:00:00

abstract：AIMS:To evaluate the influence of involvement of the peritoneal surface by carcinoma of the rectum on local recurrence and prognosis. METHODS:Prospective analysis of pathological prognostic factors in 209 resections for rectal carcinoma between 1988 and 1993 with meticulous pathological technique particularly to asses...

journal_title：Journal of clinical pathology

authors： Shepherd NA,Baxter KJ,Love SB

更新日期：1995-09-01 00:00:00

abstract：:A "Centrifichem" centrifugal analyser was found using a double fluorescence/bacterial tracer method to be a source of airborne and surface contamination in the laboratory. The airborne contamination was controlled by a modification incorporating a filter. Ubiquitous surface contamination generally accompanied the proc...

journal_title：Journal of clinical pathology

authors： Kennedy DA,Stevens JF,Horn AN

更新日期：1988-11-01 00:00:00

abstract：:Lung tissue from 13 cases of unexplained non-immunological hydrops fetalis was examined by in situ hybridisation to detect parvovirus. Four specimens contained parvovirus DNA in cells in the blood vessel lumina and alveoli. Twenty six control cases were negative for parvovirus DNA. As there was no known epidemic of pa...

journal_title：Journal of clinical pathology

authors： Porter HJ,Khong TY,Evans MF,Chan VT,Fleming KA

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:An increased level of serum C-reactive protein (CRP) is a known prognostic factor for acute coronary events and sudden cardiac death, and it is associated with coronary calcification. CRP is expressed in coronary arteries, but its role in the development of coronary plaques is unclear. AIM:To investigate CR...

journal_title：Journal of clinical pathology

authors： Norja S,Nuutila L,Karhunen PJ,Goebeler S

更新日期：2007-05-01 00:00:00

abstract：AIMS:Because sentinel lymph node (SLN) biopsy for breast cancer has become well established, one of the challenges now is to determine which patients require a completion axillary dissection following a positive SLN biopsy. METHODS:A prospective database of patients who underwent SLN biopsy for invasive breast cancer ...

journal_title：Journal of clinical pathology

authors： Fleming FJ,Kavanagh D,Crotty TB,Quinn CM,McDermott EW,O'Higgins N,Hill AD

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Hepatic fibrosis is one of the main consequences of liver disease. Both fibrosis and steatosis may be seen in some patients with chronic hepatitis C and alcoholic liver disease (ALD). AIMS:To quantitate fibrosis and steatosis by stereological and morphometric techniques in patients with chronic hepatitis C ...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,Al Mardini H,Awad S,Ukabam S,Makadisi S,Record CO

更新日期：2001-06-01 00:00:00

abstract：:Agar gel, cellulose acetate, and starch gel electrophoresis are all capable of diagnosing sickle-cell anaemia, sickle-cell haemoglobin C disease, and haemoglobin C disease in cord blood samples. Of these three electrophoretic techniques, agar gel is the easiest to interpret.Paper electrophoresis can reliably and rapid...

journal_title：Journal of clinical pathology

authors： Yaswon GI,Huntsman RG,Metters JS

更新日期：1970-09-01 00:00:00

abstract：:Gonococcal isolates resistant to ciprofloxacin collected from 2004 to 2005, in the Pretoria region, were characterised using Neisseria gonorrhoeae multi-antigen sequence typing (NG-MAST). The isolates were obtained from men presenting with urethritis to primary healthcare clinics and general practitioners. All isolate...

journal_title：Journal of clinical pathology

authors： De Jongh M,Dangor Y,Ison CA,Hoosen AA

更新日期：2008-05-01 00:00:00

abstract：AIMS:To establish a three dimensional reconstruction of an invasive breast carcinoma using basic laboratory equipment to evaluate and characterise the spatial arrangement of the parenchymal cells of the breast. METHODS:One hundred and twenty eight sequential 4 microm sections (20 microm apart) of the tumour were stain...

journal_title：Journal of clinical pathology

authors： Kurien T,Boyce RW,Paish EC,Ronan J,Maddison J,Rakha EA,Green AR,Ellis IO

更新日期：2005-09-01 00:00:00

abstract：:A modified nitroblue tetrazolium test (NBT) is described which is suitable for routine application in the haematology or bacteriology laboratory and which provides a rapid aid to the diagnosis of bacterial infection. Hitherto published methods have recommended the use of heparinized whole blood samples for the perform...

journal_title：Journal of clinical pathology

authors： Gordon AM,Rowan RM,Brown T,Carson HG

更新日期：1973-01-01 00:00:00

abstract：AIMS:To document the features of the so-called aplastic presentation of childhood acute lymphoblastic leukaemia (ALL) and to determine whether this prodrome can be distinguished from aplasia. METHODS:The peripheral blood and bone marrow appearances of all cases of childhood ALL presenting in one health region of Engla...

journal_title：Journal of clinical pathology

authors： Reid MM,Summerfield GP

更新日期：1992-08-01 00:00:00

abstract：:It was shown that, on average, the titres of the sera obtained by both the anti-complement immunofluorescence (ACIF) and indirect immunofluorescence for viral late antigens (IFA-LA) procedures were approximately eight times higher than those obtained by complement fixation. There was no significant difference between ...

journal_title：Journal of clinical pathology

authors： Griffiths PD,Buie KJ,Heath RB

更新日期：1978-09-01 00:00:00

abstract：:The cellularity of 104 primary breast carcinomata was determined by semiautomated image analysis to allow the relation between cellularity and oestrogen receptor content values to be assessed. The oestrogen receptor content of tumours detected by a steroid binding assay showed no correlation with cellularity, although...

journal_title：Journal of clinical pathology

authors： Parham DM,Baker PR,Robertson AJ,Vasishta A,Baker PG,Smith G

更新日期：1989-11-01 00:00:00