A comparison of complement fixation, indirect immunofluorescence for viral late antigens, and anti-complement immunofluorescence tests for the detection of cytomegalovirus specific serum antibodies.

abstract：AIMS:The localisation of the translocation breakpoint of the Ewing sarcoma family of tumours shows significant variability on relatively large regions of fusion partner genes. As a consequence, many alternative forms of EWSR1-ETS translocation exist which make the RNA-based molecular diagnostics of Ewing sarcoma family...

journal_title：Journal of clinical pathology

authors： Patócs B,Németh K,Garami M,Arató G,Kovalszky I,Szendroi M,Fekete G

更新日期：2012-12-01 00:00:00

abstract：:Experiments were performed to evaluate five commercial kit assays used for the detection of antibodies to dsDNA. The kits were compared using a performance index score as recommended by the guidelines of the European Committee for Clinical Laboratory Standards. The highest performance score was obtained using the radi...

journal_title：Journal of clinical pathology

authors： McMillan SA,Fay AC

更新日期：1988-11-01 00:00:00

abstract：AIMS:To evaluate aspects of the current practice of sentinel lymph node (SLN) pathology in breast cancer via a questionnaire based survey, to recognise major issues that the European guidelines for mammography screening should address in the next revision. METHODS:A questionnaire was circulated by mail or electronical...

journal_title：Journal of clinical pathology

authors： Cserni G,Amendoeira I,Apostolikas N,Bellocq JP,Bianchi S,Boecker W,Borisch B,Connolly CE,Decker T,Dervan P,Drijkoningen M,Ellis IO,Elston CW,Eusebi V,Faverly D,Heikkila P,Holland R,Kerner H,Kulka J,Jacquemier J,La

更新日期：2004-07-01 00:00:00

abstract：:Cytological diagnosis in a series of 153 skin lesions is presented. The diagnosis in each case has been compared with the clinical assessment and, where available, the biopsy result (85 lesions). Of 131 basal cell carcinomas, a cytological diagnosis was possible in 124 while biopsyl failed to identify two of the 73 le...

journal_title：Journal of clinical pathology

authors： Brown CL,Klaber MR,Robertson MG

更新日期：1979-04-01 00:00:00

abstract：AIMS:Positive direct antiglobulin tests (DATs) are valuable in identifying the aetiology of autoimmune haemolysis and in guiding therapeutic intervention. However, in HIV-positive individuals with background polyclonal gammopathy, a positive DAT in the absence of haemolysis is common. In this setting, IgG quantificatio...

journal_title：Journal of clinical pathology

authors： Chetty T,Bouwer N,Wan YO,Mahlangu J

更新日期：2020-12-16 00:00:00

abstract：:The Fisher Hem-Alyzer is a multitest sequential discrete analyser with automatic printout of digitized results on paper tape. The instrument is well designed, soundly constructed, and reliable in routine use. Cross contamination from the sampler probe or between the cuvettes is minimal. Accuracy and precision are both...

journal_title：Journal of clinical pathology

authors： Lappin TR,Lamont A,Nelson MG

更新日期：1970-02-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) testing is required for newly diagnosed breast cancer and advised for recurrent and metastatic breast cancer, to determine treatment planning using HER2-directed therapy in the neoadjuvant, adjuvant and advanced disease settings. Wide variation, nationally, in the turnar...

journal_title：Journal of clinical pathology

authors： Shaaban AM,Purdie CA,Bartlett JM,Stein RC,Lane S,Francis A,Thompson AM,Pinder SE,Translational Subgroup of the NCRI Breast Clinical Studies Group.

更新日期：2014-02-01 00:00:00

abstract：AIMS:The incidence of RAS/RAF/PI3KA and TP53 gene mutations in colorectal cancer (CRC) is well established. Less information, however, is available on other components of the CRC genomic landscape, which are potential CRC prognostic/predictive markers. METHODS:Following a previous validation study, ion-semiconductor n...

journal_title：Journal of clinical pathology

authors： Malapelle U,Pisapia P,Sgariglia R,Vigliar E,Biglietto M,Carlomagno C,Giuffrè G,Bellevicine C,Troncone G

更新日期：2016-09-01 00:00:00

abstract：:In October 1859, 'The Queen of Hearts' was published by Wilkie Collins. This book is a collection of 10 short stories written by the protagonists (three retired brothers), in order to keep their niece (aka the queen of hearts) entertained, until the arrival of her fiancé-to-be. The second story of the book, titled 'Br...

journal_title：Journal of clinical pathology

authors： Fernandez-Flores A

更新日期：2011-02-01 00:00:00

abstract：:Enteroviruses are rare causes of acute focal encephalitis. A fatal case of echovirus type 9 infection is reported in a 9 month old boy who presented with a fever and a macular rash followed by two focal seizures. Echovirus type 9 was isolated from lung tissue after seven days. ...

journal_title：Journal of clinical pathology

authors： Zuckerman MA,Sheaff M,Martin JE,Gabriel CM

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The "classical" antineutrophil cytoplasmic antibody (C-ANCA) pattern seen on indirect immunofluorescence (IIF) is characterised by granular cytoplasmic staining showing central or interlobular accentuation, and is strongly associated with antiproteinase-3 antibodies (PR3-ANCA) and Wegener's granulomatosis. H...

journal_title：Journal of clinical pathology

authors： Wong RC,Silvestrini RA,Savige JA,Fulcher DA,Benson EM

更新日期：1999-02-01 00:00:00

abstract：:By means of enzyme immunoassays based on two monoclonal antibodies with specificities for distinct forms of placental type alkaline phosphatase (Pl-ALP), together with L-leucine inhibition studies, it has been possible to distinguish the Nagao type carcinoplacental enzyme from other placental type alkaline phosphatase...

journal_title：Journal of clinical pathology

authors： McLaughlin PJ,Twist AM,Evans CC,Johnson PM

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND/AIMS:Mast cells, when activated, secrete a large number of fibrogenic factors and have been implicated in the development of fibrotic conditions of the liver, lung, and skin. There is evidence that renal fibrosis is closely linked with a chronic inflammatory cell infiltrate within the interstitium, but a pot...

journal_title：Journal of clinical pathology

authors： Roberts IS,Brenchley PE

更新日期：2000-11-01 00:00:00

abstract：AIMS:Next Generation Sequencing (NGS)-based BRCA tumour tissue testing poses several challenges. As a first step of its implementation within a regional health service network, an in-house validation study was compared with published recommendations. METHODS:Epithelial ovarian cancer (EOC) formalin-fixed paraffin-embe...

journal_title：Journal of clinical pathology

authors： Rivera D,Paudice M,Gismondi V,Anselmi G,Vellone VG,Varesco L,Ligurian BRCA Working Group.

更新日期：2020-09-07 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：:A blood group change from A2 to Ax is described in a boy who had Fallot's tetralogy, oesophageal atresia, and a tracheo-oesophageal fistula. The change of blood group created a transfusion problem. The unusual serology is discussed. ...

journal_title：Journal of clinical pathology

authors： Bird GW,Roberts KD,Wingham J

更新日期：1975-12-01 00:00:00

abstract：AIMS:To investigate the relation between sarcoidosis and lymphoma. METHODS:The hospital notes of five patients with sarcoidosis and a lymphoproliferative disorder were reviewed. Histological material on which the diagnoses of sarcoidosis and lymphoma were made was re-analysed. RESULTS:Four of the five patients had we...

journal_title：Journal of clinical pathology

authors： Karakantza M,Matutes E,MacLennan K,O'Connor NT,Srivastava PC,Catovsky D

更新日期：1996-03-01 00:00:00

abstract：:Guinea-pigs, rats, dogs, rabbits, monkeys, sheep, and goats were screened for G-6PD activity in erythrocytes by the methaemoglobin reduction test, the brilliant cresyl blue decolorization test, and the spectrophotometric determination of the NADPH generation rate. Guinea-pigs, rats, dogs, rabbits, and monkeys were fou...

journal_title：Journal of clinical pathology

authors： Cheun LH

更新日期：1966-11-01 00:00:00

abstract：:Review of published work and analysis of clinical data and pathology of four biopsy specimens from two patients with laryngeal contact granuloma showed that its peptic origin was derived from a gastro-oesophago-laryngeal reflux. It is proposed that the term "peptic granuloma" should be given to this phenomenon. This t...

journal_title：Journal of clinical pathology

authors： Miko TL

更新日期：1989-08-01 00:00:00

abstract：:The cardiovascular system is a common target of amyloidosis. This review presents the current clinical and diagnostic approach to amyloidosis, with the emphasis on cardiovascular involvement. It summarises recent nomenclature, classification, and pathogenesis of amyloidosis. In addition, non-invasive possibilities are...

journal_title：Journal of clinical pathology

authors： Kholová I,Niessen HW

更新日期：2005-02-01 00:00:00

abstract：:The laboratory findings in seven cases of endocarditis caused by coagulase-negative staphylococci are presented. The usefulness of biochemical characterization of the strains in diagnosis and the selection of antibiotics for prophylaxis and treatment are discussed. ...

journal_title：Journal of clinical pathology

authors： Speller DC,Mitchell RG

更新日期：1973-07-01 00:00:00

abstract：BACKGROUND:In primary cutaneous melanoma, the sentinel node (SN) biopsy is an accurate method for the staging of the lymph nodes. Positron emission tomography (PET) has been suggested as a useful alternative. However, the sensitivity of PET may be too low to detect SN metastases, which are often small. AIM:To predict ...

journal_title：Journal of clinical pathology

authors： Mijnhout GS,Hoekstra OS,van Lingen A,van Diest PJ,Adèr HJ,Lammertsma AA,Pijpers R,Meijer S,Teule GJ

更新日期：2003-04-01 00:00:00

abstract：:A spectrophotometric assay of proteolytic enzyme activity is described in which the optical density obtained by a given enzyme preparation is related (2 alpha less than 0.01) to the serological activity of that preparation in a two stage technique. The assay appears to be of use for the standardisation of enzyme prepa...

journal_title：Journal of clinical pathology

authors： Phillips PK,Prior D,Dawes B

更新日期：1984-03-01 00:00:00

abstract：:A simple, cheap and readily available test system for biological safety cabinets is described. It depends on the containment of an aerosol of Bacillus subtilis spores generated in a BIRD micronebulizer and the measurement of air flows with an anemometer. The system was set up to survey new equipment but equally valuab...

journal_title：Journal of clinical pathology

authors： Newsom SW

更新日期：1974-07-01 00:00:00

abstract：AIMS:To assess the effect of cellulosic dialysis membranes on the production of complement degradation products to determine to the role of the classical pathway. METHOD:Complement activation was studied in 33 patients during a single haemodialysis session using cellulosic membranes. Pre- and post-dialysis plasma EDTA...

journal_title：Journal of clinical pathology

authors： Innes A,Farrell AM,Burden RP,Morgan AG,Powell RJ

更新日期：1994-02-01 00:00:00

abstract：:Cervical biopsies from 97 women with malignant cells in cervical scrape smears have been studied. Forty-eight patients had invasive squamous carcinoma, and 49 had intraepithelial lesions. Of these, six had dedifferentiated carcinoma in situ, nine had the differentiated lesions generally known as ;severe dysplasia', an...

journal_title：Journal of clinical pathology

authors： Grubb C,Janota I

更新日期：1967-01-01 00:00:00

abstract：:A patient complained of severe diarrhoea for about four years. About 2.5 m of the jejunum was resected and duodenal polyps were also removed at laparotomy. Histologically, they were tubular or tubulovillus adenomas, which closely resembled colonic adenomas. No malignant change was detected in these adenomas. Severe in...

journal_title：Journal of clinical pathology

authors： Nakamura T,Kimura H,Nakano G

更新日期：1986-09-01 00:00:00

abstract：:Two cases of peritoneal granulomatous reactions to food starch are described. They followed bowel perforation and clinically mimicked tuberculous and glove-powder starch peritonitis. Their histological differences from corn-starch peritonitis warrant attention in the absence of previous documentation of starch as a co...

journal_title：Journal of clinical pathology

authors： Davies JD,Ansell ID

更新日期：1983-04-01 00:00:00

abstract：:Tumour tissue from 29 patients with primary brain lymphoma was reviewed to determine if there was an aetiological association between Epstein-Barr virus and polyclonal and monoclonal lymphoproliferations. The morphology and immunophenotype in 24 patients for whom paraffin wax embedded tissue was available were studied...

journal_title：Journal of clinical pathology

authors： Murphy JK,Young LS,Bevan IS,Lewis FA,Dockey D,Ironside JW,O'Brien CJ,Wells M

更新日期：1990-03-01 00:00:00

abstract：:A 60 year old woman with disseminated ductal carcinoma of the breast developed non-islet cell tumour induced hypoglycaemia (NICTH). The concentrations of the two insulin-like growth factors, IGF-I and IGF-II, were < 2 nmol/l and 94.1 nmol/l, respectively. The IGF-II to IGF-I ratio was > 47 (normal < 10). Insulin (< 3 ...

journal_title：Journal of clinical pathology

authors： Bessell EM,Selby C,Ellis IO

更新日期：1999-10-01 00:00:00