Mitochondrial DNA haplotyping revealed the presence of mixed up benign and neoplastic tissue sections from two individuals on the same prostatic biopsy slide.

abstract：:Cytological diagnosis in a series of 153 skin lesions is presented. The diagnosis in each case has been compared with the clinical assessment and, where available, the biopsy result (85 lesions). Of 131 basal cell carcinomas, a cytological diagnosis was possible in 124 while biopsyl failed to identify two of the 73 le...

journal_title：Journal of clinical pathology

authors： Brown CL,Klaber MR,Robertson MG

更新日期：1979-04-01 00:00:00

abstract：:Sections from 100 cervical biopsy specimens were studied by 12 consultant histopathologists to determine the robustness of the existing pathology terminology and classification. Analysis by kappa statistics showed good agreement in the diagnosis of CIN 3 and squamous carcinoma but an inability to distinguish accuratel...

journal_title：Journal of clinical pathology

authors： Robertson AJ,Anderson JM,Beck JS,Burnett RA,Howatson SR,Lee FD,Lessells AM,McLaren KM,Moss SM,Simpson JG

更新日期：1989-03-01 00:00:00

abstract：:A total of 104 clinical isolates of Pr. mirabilis from three hospitals were screened for their sensitivity to chlorhexidine. The minimum inhibitory concentrations of the antiseptic for these strains ranged from 10 to 800 mug/ml. Two strains sensitive to 20 mug of chlorhexidine/ml were adapted to resistance by growth i...

journal_title：Journal of clinical pathology

authors： Stickler DJ

更新日期：1974-04-01 00:00:00

abstract：:Urines from patients with symptoms of urinary tract infection yielded mixed growths of different colony types of Escherichia coli. The different colony types were found to be variants of single infecting strains caused by mutation or by phase action. It is suggested that care should be exercised in the interpretation ...

journal_title：Journal of clinical pathology

authors： Nichols GL

更新日期：1975-09-01 00:00:00

abstract：:A latex enzyme immunoassay (LEIA) for detecting IgG class antibody to rubella virus was compared with the latex agglutination test (LA) and a haemagglutination inhibition assay (HI). Of 243 sera tested, four discrepant results were observed among all three techniques, corresponding to borderline values. Except for one...

journal_title：Journal of clinical pathology

authors： Duverlie G,Roussel C,Driencourt M,Orfila J

更新日期：1990-09-01 00:00:00

abstract：AIMS:To describe and evaluate two apparently unique cases of inverted hyperplastic (metaplastic) polyposis of the colon. METHODS:The cases were analysed by standard histopathological, histochemical, and immunohistochemical techniques and the findings compared with those of regular hyperplastic polyps of the colorectum...

journal_title：Journal of clinical pathology

authors： Shepherd NA

更新日期：1993-01-01 00:00:00

abstract：:Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...

journal_title：Journal of clinical pathology

authors： Booth SN,Lakin G,Dykes PW,Burnett D,Bradwell AR

更新日期：1977-06-01 00:00:00

abstract：AIMS:To compare the expression of immunohistochemical variables between benign and malignant components of malignant peripheral nerve sheath tumour (MPNST) arising within neurofibroma. METHODS:Eight cases of MPNST arising within a neurofibroma, associated with neurofibromatosis type 1 (NF1), were studied. The areas of...

journal_title：Journal of clinical pathology

authors： Watanabe T,Oda Y,Tamiya S,Masuda K,Tsuneyoshi M

更新日期：2001-08-01 00:00:00

abstract：:Current techniques for lymphocyte transformation are evaluated and criticised. A simple technique, designed to meet these criticisms, is described in detail, with particular reference to lymphocyte separation and scoring methods. ...

journal_title：Journal of clinical pathology

authors： Pentycross CR

更新日期：1968-03-01 00:00:00

abstract：:The case records and pathology of all children with kidney tumours treated in the West Midlands Health Authority Region (WMHAR) from 1957 to 1986 were reviewed. The histology was reviewed by a panel of three paediatric pathologists. Thirteen (6%) out of 211 cases were considered to have congenital mesoblastic nephroma...

journal_title：Journal of clinical pathology

authors： Barrantes JC,Toyn C,Muir KR,Parkes SE,Raafat F,Cameron AH,Marsden HB,Mann JR

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Raised plasma ferritin concentrations occur unexpectedly during iron studies done by primary care physicians. Plasma ferritin concentration has been positively associated with alcohol use among men. AIM:To determine the post-test probability that men in the community with raised plasma ferritin concentratio...

journal_title：Journal of clinical pathology

authors： Peach HG,Bath NE

更新日期：1999-11-01 00:00:00

abstract：:Guidance by bacteriologists and changes in theatre and ward disciplines have greatly improved the results of urological surgery in recent years. The most noteworthy successes have been in treatment of chronic retention with renal failure, and in prevention of the bacteraemia which may occur following removal of the po...

journal_title：Journal of clinical pathology

authors： MITCHELL JP,GILLESPIE WA

更新日期：1964-09-01 00:00:00

abstract：:Thirteen meningiomas of varying light microscopic features were studied immunohistologically using a panel of monoclonal antibodies directed against epithelial, mesenchymal, and neural components. All 13 meningiomas showed expression of epithelial membrane antigen, vimentin, and S100 protein, as did normal meninges. F...

journal_title：Journal of clinical pathology

authors： Theaker JM,Gatter KC,Esiri MM,Fleming KA

更新日期：1986-04-01 00:00:00

abstract：:A chemical method for the sterilization of pancreatin and trypsin is given. Evidence is presented to show that this treatment does not diminish the specific activity of the enzymes and has some advantages in microbiological techniques. ...

journal_title：Journal of clinical pathology

authors： Stokes KJ

更新日期：1971-10-01 00:00:00

abstract：:Rosetting and non-rosetting lymphocytes collected from normal individuals were stained for the presence of beta-glucuronidase, periodic-acid Schiff activity, gamma glutamyl transpeptidase, acid phosphatase, and alpha-naphthyl butyrate esterase. Lymphocytes which formed rosettes with sheep erythrocytes and non-rosette ...

journal_title：Journal of clinical pathology

authors： Davey FR,Huntington SJ,Maccallum J,Macmath JM

更新日期：1977-07-01 00:00:00

abstract：AIMS:To investigate a potential diagnostic use of alpha fetoprotein (alpha FP) isoform analysis by lectin affinity electrophoresis to distinguish between endodermal sinus tumours arising in the vagina in infants from those at other sites. METHODS:alpha FP in the serum of a patient with a vaginal endodermal sinus tumou...

journal_title：Journal of clinical pathology

authors： Yamamoto R,Taketa K,Ebina Y,Cho Y,Hareyama H,Sakuragi N,Makinoda S,Kobayashi K,Nishi S,Fujimoto S

更新日期：1997-10-01 00:00:00

abstract：AIMS:Optical microscopic (OM) evaluation of peripheral blood (PB) cells is still a crucial step of the laboratory haematological workflow. The morphological cell analysis is time-consuming and expensive and it requires skilled operator. To address these challenges, automated image-processing systems, as digital morphol...

journal_title：Journal of clinical pathology

authors： Da Rin G,Benegiamo A,Di Fabio AM,Dima F,Francione S,Fanelli A,Germagnoli L,Lorubbio M,Marzoni A,Pajola R,Pipitone S,Rolla R,Seghezzi M,Baigorria Vaca MDC,Bartolini A,Buoro S

更新日期：2020-09-14 00:00:00

abstract：:A radioimmunoassay for human growth hormone using activated charcoal is described and its precision, accuracy, and sensitivity are defined. Results are presented for growth hormone measurements in plasma obtained during hypoglycaemia induced with insulin in patients of short stature and during glucose tolerance tests ...

journal_title：Journal of clinical pathology

authors： Thomas FJ,Lloyd HM,Thomas MJ

更新日期：1972-09-01 00:00:00

abstract：:Rates of urinary excretion concomitant with the molecular size distribution of filtered polymer fragments were determined in five normovolaemic men dosed with 30 g/m2 BSA of a species of HES (HES 350/0.60) possessing a M-W of 350 000 combined with an MS of 0.60. Approximately 13% of the total injected dose of HES 350/...

journal_title：Journal of clinical pathology

authors： Mishler JM,Ricketts CR,Parkhouse EJ

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterised by the presence of various laboratory abnormalities but the precise role of laboratory staff in initiating clinical referral and subsequent biopsy is not clear. OBJECTIVE:To examine the impact of laboratory abnormalities in the inv...

journal_title：Journal of clinical pathology

authors： Sinclair D,Spedding A,Young R

更新日期：2006-04-01 00:00:00

abstract：:Squamous cell carcinoma arising in ovarian endometriosis is extremely rare, but a case is reported in a 62 year old woman. If such an ovarian tumour is discovered evidence of teratoma, Brenner tumour, or endometriosis should be sought. Extensive sampling is mandatory as the developing tumour often overgrows the foci o...

journal_title：Journal of clinical pathology

authors： Naresh KN,Ahuja VK,Rao CR,Mukherjee G,Bhargava MK

更新日期：1991-11-01 00:00:00

abstract：:Serine esterases were detected in the granules of mucosal mast cells from rat, mouse, sheep, and man. Successful demonstration of enzyme activity required brief fixation (6 h) of tissues in 4% paraformaldehyde. Staining with naphthol AS-D chloroacetate produced an intense red reaction product in intraepithelial mucosa...

journal_title：Journal of clinical pathology

authors： Huntley JF,Newlands GF,Gibson S,Ferguson A,Miller HR

更新日期：1985-04-01 00:00:00

abstract：:A rapid technique using a non-radioactive receptor molecule (digoxigenin) for intrahepatic hepatitis B virus (HBV) DNA detection using in situ hybridisation was developed. It can be adapted for use in combination with standard immunohistochemistry for simultaneous detection of both HBV DNA and HBV antigens. The total ...

journal_title：Journal of clinical pathology

authors： Lau JY,Naoumov NV,Alexander GJ,Williams R

更新日期：1991-11-01 00:00:00

abstract：:It is found that serum antifibrinolytic activity is inhibitory both to the spontaneous fibrinolytic activity and to the activity of streptokinase-activated plasminogen. The titres of serum antiplasmin activity during gestation, labour, and the puerperium are all of the same order and do not differ from those in non-pr...

journal_title：Journal of clinical pathology

authors： BIEZENSKI JJ

更新日期：1960-05-01 00:00:00

abstract：AIMS:To describe characteristics of a series of people accidentally and deliberately killed by air powered weapons. METHODS:Five cases of fatal airgun injury were identified by forensic pathologists and histopathologists. The circumstances surrounding the case, radiological examination, and pathological findings are d...

journal_title：Journal of clinical pathology

authors： Milroy CM,Clark JC,Carter N,Rutty G,Rooney N

更新日期：1998-07-01 00:00:00

abstract：:This paper describes the modification of a commercially available rapid slide screening test(1) for anti-streptolysin O to give quantitative results. The modified technique is compared with the long-established haemolytic technique of Rantz and Randall (1945). The quantitative results for both techniques are shown to ...

journal_title：Journal of clinical pathology

authors： Ingram GB,Hughes JE

更新日期：1972-06-01 00:00:00

abstract：:Acute myocardial disease, which may be associated with abnormal platelet activity, has been reported after routine immunisation. Thirty-two army apprentices undergoing immunisation were studied for changes in the heparin neutralising activity (HNA) of platelet poor plasma. HNA increased after immunisation. This increa...

journal_title：Journal of clinical pathology

authors： Baker IA,Howells CH,O'Brien JR

更新日期：1979-11-01 00:00:00

abstract：:Sentinel lymph node biopsy is a novel method for the surgical management of patients with cervical cancer. Sentinel nodes have a higher chance of harbouring metastases than non-sentinel nodes. Assessment of sentinel nodes provides an opportunity to stage patients intraoperatively and avoid complete pelvic lymph node d...

journal_title：Journal of clinical pathology

authors： Rasty G,Hauspy J,Bandarchi B

更新日期：2009-12-01 00:00:00

abstract：:This paper urges the benefits of applying more widely a method for pathology laboratory costing originally devised for a clinical chemistry department, and illustrates these with examples drawn from costing studies in three clinical laboratories. Heads of pathology departments, laboratory managers, administrators and ...

journal_title：Journal of clinical pathology

authors： Broughton PM,Woodford FP

更新日期：1983-09-01 00:00:00

abstract：:The macrophage markers non-specific esterase, alpha 1-antitrypsin, alpha 1-antichymotrypsin, and lysozyme were compared with conventional microglial and macrophage stains in the human central nervous system. In a series of specimens from cases of head trauma, conventionally fixed and embedded, the modified Weil-Davenp...

journal_title：Journal of clinical pathology

authors： Esiri MM,Booss J

更新日期：1984-02-01 00:00:00