Observer variability in histopathological reporting of cervical biopsy specimens.

abstract：:A recently developed procedure, that has been shown to be suitable for detailed immunohistological analysis, has been used to prepare cryostat sections of bone marrow to investigate whether enzyme-histochemical techniques are also feasible on such material. A selected group of enzymes, some of which are inhibited or d...

journal_title：Journal of clinical pathology

authors： Chilosi M,Pizzolo G,Janossy G,Bofill M,Fiore-Donati L

更新日期：1982-11-01 00:00:00

abstract：:A study of 260 patients with non-Hodgkin's lymphoma (NHL) who underwent bilateral bone marrow biopsy at initial diagnosis showed marrow disease in 99 (38%) cases. The highest incidence of disease (83%) was seen in small lymphocytic lymphoma (SLL) and the lowest (19%) in diffuse large cell lymphoma (DLCL). Among cases ...

journal_title：Journal of clinical pathology

authors： Juneja SK,Wolf MM,Cooper IA

更新日期：1990-08-01 00:00:00

abstract：:Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal ep...

journal_title：Journal of clinical pathology

authors： Jenkins D,Stephenson PM,Scott BB

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:The Wnt pathway is important in cell signalling transduction and is involved in the pathogenesis of multiple tumour types. A comprehensive analysis of the expression of Wnt signalling pathway proteins in mammary phyllodes tumours (PTs) has not been previously performed. AIMS:To evaluate the immunohistochemi...

journal_title：Journal of clinical pathology

authors： Karim RZ,Gerega SK,Yang YH,Horvath L,Spillane A,Carmalt H,Scolyer RA,Lee CS

更新日期：2009-11-01 00:00:00

abstract：:Pseudomonas cepacia (Ps. multivorans) can become adapted to a 1 in 30 dilution of Savlon hospital concentrate in distilled water, and can multiply in it. The organism so adapted did not survive in Savlon of the same strength made with hard tap water (pH 7.2). This effect was due to the difference of pH between the two...

journal_title：Journal of clinical pathology

authors： Bassett DC

更新日期：1971-11-01 00:00:00

abstract：:The lymphoid tissue of the normal colon is compared with that of colons with diverticular disease. Colons with diverticular disease show a significant increase in the number of lymphoid nodules in areas not containing diverticula. Lymphoid-glandular complexes of the colon were studied in relation to diverticular disea...

journal_title：Journal of clinical pathology

authors： Kealy WF

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Epstein's syndrome is defined as a subtype of Alport's syndrome, and is distinguished from the other subtypes by accompanying macrothrombocytopenia. Mutations in collagen IV genes are known to be involved in the pathogenesis of typical Alport's syndrome. However, the presence of an underlying genetic defect ...

journal_title：Journal of clinical pathology

authors： Naito I,Nomura S,Inoue S,Kagawa M,Kawai S,Gunshin Y,Joh K,Tsukidate C,Sado Y,Osawa G

更新日期：1997-11-01 00:00:00

abstract：AIMS:The histopathological diagnosis of low-grade dysplasia (LGD) in Barrett's oesophagus (BO) is associated with poor interobserver agreement and guidelines dictate expert review. To facilitate nationwide expert review in the Netherlands, a web-based digital review panel has been set up, which currently consists of ei...

journal_title：Journal of clinical pathology

authors： Klaver E,van der Wel M,Duits L,Pouw R,Seldenrijk K,Offerhaus J,Visser M,Ten Kate F,Biermann K,Brosens L,Doukas M,Huysentruyt C,Karrenbeld A,Kats-Ugurlu G,van der Laan J,van Lijnschoten I,Moll F,Ooms A,Tijssen J,Meij

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Raised plasma ferritin concentrations occur unexpectedly during iron studies done by primary care physicians. Plasma ferritin concentration has been positively associated with alcohol use among men. AIM:To determine the post-test probability that men in the community with raised plasma ferritin concentratio...

journal_title：Journal of clinical pathology

authors： Peach HG,Bath NE

更新日期：1999-11-01 00:00:00

abstract：:Human papillomavirus (HPV) infection of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma was investigated using in situ DNA-DNA hybridisation on histological sections of formalin fixed, paraffin embedded tissue to assess the technique's sensitivity and to assess retrospectively the association ...

journal_title：Journal of clinical pathology

authors： Collins JE,Jenkins D,McCance DJ

更新日期：1988-03-01 00:00:00

abstract：:Cancer lineage/tissue-of-origin assignment in cancers of unknown primary remains a challenge even when aided by massively parallel sequencing. The stakes are high for patients as many contemporary therapeutic strategies are disease-specific, and the biological differences can influence the patients' responses. Herein,...

journal_title：Journal of clinical pathology

authors： Yoon JY,Rosenbaum JN,Vergara N,Cohen RB,Wilson RB

更新日期：2020-08-27 00:00:00

abstract：:A method for the neutron activation analysis of copper in biological material is described and applied to the diagnosis and management of four cases of Wilson's disease. Results obtained for serum and urine are in agreement with values obtained by established colorimetric techniques. The method described can estimate ...

journal_title：Journal of clinical pathology

authors： Fell GS,Smith H,Howie RA

更新日期：1968-01-01 00:00:00

abstract：BACKGROUND:Cardiac remodelling after acute myocardial infarction (AMI) is characterised by molecular and cellular mechanisms involving both left and right ventricles, and biventricular failure identifies patients with an extremely unfavourable prognosis. AIMS:To assess whether a link exists between increased myocardia...

journal_title：Journal of clinical pathology

authors： Bussani R,Abbate A,Biondi-Zoccai GG,Dobrina A,Leone AM,Camilot D,Di Marino MP,Baldi F,Silvestri F,Biasucci LM,Baldi A

更新日期：2003-09-01 00:00:00

abstract：:A method is described of measuring the response of human lymphocytes to phytohaemagglutinin stimulation using iododeoxyuridine labelled with the gamma-emitting isotope (125)I. The results indicate useful clinical applications. ...

journal_title：Journal of clinical pathology

authors： Craig AW,Garrett JV,Jackson SM

更新日期：1969-09-01 00:00:00

abstract：:Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...

journal_title：Journal of clinical pathology

authors： Booth SN,Lakin G,Dykes PW,Burnett D,Bradwell AR

更新日期：1977-06-01 00:00:00

abstract：:Sera obtained from 34 men with Chlamydia trachomatis positive non-gonococcal urethritis, 34 men with C trachomatis negative non-gonococcal urethritis, 42 women with acute salpingitis, 38 healthy women, and 34 healthy men were studied for the presence of specific serum C trachomatis IgA and IgG antibodies. Serological ...

journal_title：Journal of clinical pathology

authors： Cevenini R,Sarov I,Rumpianesi F,Donati M,Melega C,Varotti C,La Placa M

更新日期：1984-06-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) testing is required for newly diagnosed breast cancer and advised for recurrent and metastatic breast cancer, to determine treatment planning using HER2-directed therapy in the neoadjuvant, adjuvant and advanced disease settings. Wide variation, nationally, in the turnar...

journal_title：Journal of clinical pathology

authors： Shaaban AM,Purdie CA,Bartlett JM,Stein RC,Lane S,Francis A,Thompson AM,Pinder SE,Translational Subgroup of the NCRI Breast Clinical Studies Group.

更新日期：2014-02-01 00:00:00

abstract：AIM:To determine the frequency, pattern and distribution of stromal keratin expression in phyllodes tumours if any, which may impact diagnostic approaches. METHODS:The clinicopathological features of 109 phyllodes tumours comprising 70 (64.2%) benign, 30 (27.5%) borderline and nine (8.3%) malignant grades were evaluat...

journal_title：Journal of clinical pathology

authors： Chia Y,Thike AA,Cheok PY,Yong-Zheng Chong L,Man-Kit Tse G,Tan PH

更新日期：2012-04-01 00:00:00

abstract：:Xanthine oxidase (XO) activity was found to be negligible in sterile human urines (less than 480 units, as presently defined, per litre). Significant XO activity was found in all urines containing more than 10(5) bacteria/ml, except for urines infected with Staphylococcus aureus, in which XO activity ranged from 347 t...

journal_title：Journal of clinical pathology

authors： Giler S,Henig EF,Urca I,Sperling O,de Vries A

更新日期：1978-05-01 00:00:00

abstract：OBJECTIVE:To describe practical experiences in the sharing of very large digital data bases of histopathological imagery via the Internet, by investigators working in Europe, North America, and South America. MATERIALS:Experiences derived from medium power (sampling density 2.4 pixels/microm) and high power (6 pixels/...

journal_title：Journal of clinical pathology

authors： Montironi R,Thompson D,Scarpelli M,Bartels HG,Hamilton PW,da Silva VD,Sakr WA,Weyn B,van Daele A,Bartels PH

更新日期：2002-06-01 00:00:00

abstract：:Four assays for the detection of alphafetoprotein (AFP) in the diagnosis of primary hepatocellular carcinoma (HCC) were evaluated. The frequency of AFP detection was compared in 89 HCC patients and in 71 patients with chronic active hepatitis/cirrhosis. Of the four assays, immunodiffusion, counterimmunoelectrophoresis...

journal_title：Journal of clinical pathology

authors： Chan SH,Heng SH,Yo SL,Oon CJ

更新日期：1980-08-01 00:00:00

abstract：:Two hundred and forty-seven strains of micro-organisms were isolated from the urinary tract of 121 patients with neurological complaints leading to paraplegia. The commonest infecting organism was E. coli and the commonest type of Proteus was P. mirabilis. Infections with more than one type of organism were present in...

journal_title：Journal of clinical pathology

authors： SCOTT TG

更新日期：1960-01-01 00:00:00

abstract：:The results of an investigation show that there is no statistically significant excess of blood group A in cases of carcinoma of the oesophagus or in cases of benign prostatic hyperplasia. ...

journal_title：Journal of clinical pathology

authors： BEASLEY WH

更新日期：1964-01-01 00:00:00

abstract：:Three adults with alpha 1-antitrypsin deficiency are described. In two of the cases the deficiency was genetically determined (cases 1 and 2), and each demonstrated unusual features of the disease. The liver in case 1 (homozygous) showed cholangiolar hyperplasia which has been recorded only once before. Case 2 (hetero...

journal_title：Journal of clinical pathology

authors： Sweeney EC

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Friend leukaemia integration-1 (FLI-1) antibody is a useful marker for Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET) and vascular tumours. However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT). AIM:To de...

journal_title：Journal of clinical pathology

authors： Mhawech-Fauceglia P,Herrmann FR,Bshara W,Odunsi K,Terracciano L,Sauter G,Cheney RT,Groth J,Penetrante R,Mhawech-Fauceglia P

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Hepatic fibrosis is one of the main consequences of liver disease. Both fibrosis and steatosis may be seen in some patients with chronic hepatitis C and alcoholic liver disease (ALD). AIMS:To quantitate fibrosis and steatosis by stereological and morphometric techniques in patients with chronic hepatitis C ...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,Al Mardini H,Awad S,Ukabam S,Makadisi S,Record CO

更新日期：2001-06-01 00:00:00

abstract：AIMS:To determine whether the monoclonal antibody (MoAb) 83D4, previously shown to be highly specific for carcinoma cells, can be used as an immunocytological marker to discriminate between benign and malignant cells in serous effusions; and to test for a correlation between expression of the antigen reacting with MoAb...

journal_title：Journal of clinical pathology

authors： Beuzelin-Yvraut M,Bourguignat A,Phillips E,Roseto A,Osinaga E

更新日期：1995-05-01 00:00:00

abstract：:In a twenty-year period 19 appendicectomy specimens were diagnosed as primary Crohn's disease. This represents 4.9% of the total number of both resection specimens and mucosal biopsies diagnosed as Crohn's disease during that time. This is a review of the main histopathological features found in these appendices and t...

journal_title：Journal of clinical pathology

authors： Allen DC,Biggart JD

更新日期：1983-06-01 00:00:00

abstract：:HeLa 229 cells were infected with genital tract strains of Chlamydia trachomatis. After incubation for varying times the infected cells were fixed and stained with the fluorescent DNA binding dyes Hoechst 33258 or DAPI for comparison with conventional Giemsa stain. Fluorochrome-treated preparations were examined by in...

journal_title：Journal of clinical pathology

authors： Salari SH,Ward ME

更新日期：1979-11-01 00:00:00

abstract：:The proportion of fimbriate strains amongst Escherichia coli freshly isolated from infected urines did not differ significantly from the proportion amongst commensal Esch. coli isolated from the bowel and from non-infected urines. It is concluded that fimbriae play no major role in the pathogenesis of Esch. coli urina...

journal_title：Journal of clinical pathology

authors： Buck AC

更新日期：1967-01-01 00:00:00