Granulomatous disease in the vermiform appendix.

abstract：AIMS:To assess the relevance of genetic variants of hepatitis B virus (HBV) and to demonstrate the usefulness of the polymerase chain reaction (PCR) in cases of HBV diagnostic difficulty. METHODS:Five serum samples from patients that presented diagnostic difficulty in routine laboratories were sent to a research labor...

journal_title：Journal of clinical pathology

authors： van Deursen FJ,Hino K,Wyatt D,Molyneaux P,Yates P,Wallace LA,Dow BC,Carman WF

更新日期：1998-02-01 00:00:00

abstract：:The concentrations of selenium, zinc, and copper were determined in whole blood, plasma, and leucocytes in 20 patients with relatively mild Crohn's disease, nine of whom were being treated with steroids, and compared with those of a control group. There was a significant decrease in the concentration of selenium in th...

journal_title：Journal of clinical pathology

authors： Hinks LJ,Inwards KD,Lloyd B,Clayton B

更新日期：1988-02-01 00:00:00

abstract：AIMS:Several studies have reported conflicting and inconclusive results concerning the clinical relevance of mucin expression in gastric carcinoma. This study investigated the correlations between aberrant expression of mucins in gastric carcinoma and patient clinicopathological features. METHODS:The expression of MUC...

journal_title：Journal of clinical pathology

authors： Wang RQ,Fang DC

更新日期：2003-05-01 00:00:00

abstract：AIMS:Computational pathology platforms incorporate digital microscopy with sophisticated image analysis to permit rapid, continuous measurement of protein expression. We compared two computational pathology platforms on their measurement of breast tumour oestrogen receptor (ER) and progesterone receptor (PR) expression...

journal_title：Journal of clinical pathology

authors： Ahern TP,Beck AH,Rosner BA,Glass B,Frieling G,Collins LC,Tamimi RM

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Autoreactive humoral and cellular immune responses may be involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC). Certain human leucocyte antigens (HLA) could also be linked to the development of IDC. AIM:To determine whether various markers of autoimmunity are present in the final phase of...

journal_title：Journal of clinical pathology

authors： de Leeuw N,Melchers WJ,Ruiter DJ,Caforio AL,Balk AH,de Jonge N,Galama JM

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the protein expression of connexin 43 (Cx43) in primary urothelial bladder cancer and test its association with the histopathological characteristics and clinical outcome. METHODS:A tissue microarray containing 348 tissue samples from 174 patients with primary urothelial carcinomas of the bladde...

journal_title：Journal of clinical pathology

authors： Poyet C,Buser L,Roudnicky F,Detmar M,Hermanns T,Mannhard D,Höhn A,Rüschoff J,Zhong Q,Sulser T,Moch H,Wild PJ

更新日期：2015-10-01 00:00:00

abstract：AIMS:The perforin mediated pathway is the major pathway of cytotoxicity induced by activated T cells and natural killer cells, and may be involved in the development of pulmonary fibrosis. METHODS:Perforin and granzyme B expression were examined in idiopathic pulmonary fibrosis by means of immunohistochemistry, and pe...

journal_title：Journal of clinical pathology

authors： Miyazaki H,Kuwano K,Yoshida K,Maeyama T,Yoshimi M,Fujita M,Hagimoto N,Yoshida R,Nakanishi Y

更新日期：2004-12-01 00:00:00

abstract：:Although the UK National Institute for Health and Care Excellence guidelines recommend that in patients with biopsy-proven invasive lobular carcinoma (ILC), preoperative MRI scan is considered, the accuracy of diagnosis of ILC in core biopsy of the breast has not been previously investigated. Eleven pathology laborato...

journal_title：Journal of clinical pathology

authors： Naidoo K,Beardsley B,Carder PJ,Deb R,Fish D,Girling A,Hales S,Howe M,Wastall LM,Lane S,Lee AH,Philippidou M,Quinn C,Stephenson T,Pinder SE

更新日期：2016-12-01 00:00:00

abstract：:A new sensitive nitrite test, the SRN test, was evaluated for its suitability as a reliable screening technique for the detection of bacteriuria. The SRN test was compared to a currently available nitrite test, the Microstix nitrite test, and the results obtained with both nitrite tests were assessed in comparison wit...

journal_title：Journal of clinical pathology

authors： Rabi T

更新日期：1981-07-01 00:00:00

abstract：AIMS:Our laboratory is a centralised centre receiving routine non-small cell lung cancer (NSCLC) samples for programmed death ligand-1 (PD-L1) immunohistochemical (IHC) evaluation. Since literature data are not concordant here we review our clinical records to assess the rate of PD-L1 positive and negative NSCLC cases ...

journal_title：Journal of clinical pathology

authors： Vigliar E,Malapelle U,Iaccarino A,Acanfora G,Pisapia P,Clery E,De Luca C,Bellevicine C,Troncone G

更新日期：2019-06-01 00:00:00

abstract：:Two cases of chronic coronary periarteritis associated with chronic periaortitis are described. In one, the chronic periaortitis took the form of perianeurysmal fibrosis around a thoracic atherosclerotic aneurysm; in the other it resembled idiopathic retroperitoneal fibrosis. The findings in the two subjects support t...

journal_title：Journal of clinical pathology

authors： Mitchinson MJ,Wight DG,Arno J,Milstein BB

更新日期：1984-01-01 00:00:00

abstract：AIMS:To study whether differences in eradication rates of antibiotics may be explained by differences in secretion of antibiotics in gastric juice. METHODS:A single intravenous dose of either ampicillin 500 mg, erythromycin 500 mg, or metronidazole 500 mg was administered to four healthy Helicobacter pylori negative v...

journal_title：Journal of clinical pathology

authors： van Zanten SJ,Goldie J,Hollingsworth J,Silletti C,Richardson H,Hunt RH

更新日期：1992-03-01 00:00:00

abstract：:A labial biopsy technique is described and was used to study 40 patients with connective tissue disease and 60 postmortem subjects. More than one focus of lymphocytes per 4 sq mm of minor salivary tissue was found to be a consistent finding in patients with Sjögren's disease. The labial biopsy is shown to be a further...

journal_title：Journal of clinical pathology

authors： Chisholm DM,Mason DK

更新日期：1968-09-01 00:00:00

abstract：AIMS:Most benign breast fibroepithelial lesions (FEL) in adults harbour recurrent somatic MED12 exon 2 mutations and rare TERT promoter hotspot mutations. We sought to determine the frequency of MED12 exon 2 and TERT promoter hotspot mutations in fibroadenomas (FA) and benign phyllodes tumours (BePT) in adolescents and...

journal_title：Journal of clinical pathology

authors： Pareja F,Da Cruz Paula A,Murray MP,Hoang T,Gularte-Mérida R,Brown D,da Silva EM,Sebastiao APM,Giri DD,Weigelt B,Reis-Filho JS,Brogi E

更新日期：2019-03-01 00:00:00

abstract：:A histochemical method is described of differentiating between normal and neoplastic cells in plasma using the activity of various enzymes characteristic of plasma cells. It was found that in both types of cell increased or diminished activity of cytoenzymes is a useful means of distinguishing between normal and abnor...

journal_title：Journal of clinical pathology

authors： SZMIGIELSKI S,LITWIN J,ZUPANSKA B

更新日期：1965-05-01 00:00:00

abstract：:Myelomatosis was diagnosed in a 64 year old man on the basis of a serum paraprotein band (type IgG lambda, 42 g/l), plasma cell infiltration of bone marrow, and multiple lytic lesions evident on skull x ray picture. Blood specimens taken into plain glass tubes showed bulky gelatinous clot formation with minimal clot r...

journal_title：Journal of clinical pathology

authors： O'Kane MJ,Wisdom GB,Desai ZR,Archbold GP

更新日期：1994-03-01 00:00:00

abstract：:Gastrointestinal (GI) symptoms including abdominal pain, bloating and diarrhoea are a relatively common reason for consulting a physician. They may be due to inflammatory bowel disease (inflammatory bowel disease; Crohn's disease, ulcerative colitis and indeterminate colitis), malignancy (colorectal cancer), infectiou...

journal_title：Journal of clinical pathology

authors： Sherwood RA

更新日期：2012-11-01 00:00:00

abstract：:A 19 year old man presented with unilateral testicular swelling and pain. An initial diagnosis of epididymo-orchitis was modified to a presumed testicular neoplasm following ultrasonography. The final diagnosis of isolated testicular vasculitis was established following histological examination of the orchidectomy spe...

journal_title：Journal of clinical pathology

authors： Warfield AT,Lee SJ,Phillips SM,Pall AA

更新日期：1994-12-01 00:00:00

abstract：:Lung tissue from 13 cases of unexplained non-immunological hydrops fetalis was examined by in situ hybridisation to detect parvovirus. Four specimens contained parvovirus DNA in cells in the blood vessel lumina and alveoli. Twenty six control cases were negative for parvovirus DNA. As there was no known epidemic of pa...

journal_title：Journal of clinical pathology

authors： Porter HJ,Khong TY,Evans MF,Chan VT,Fleming KA

更新日期：1988-04-01 00:00:00

abstract：:Forty six lymph nodes were examined with the indirect immunoperoxidase technique for the distribution of fibronectin and laminin. Fibronectin was present in the framework of the tissue and the basal lamina of blood vessels, giving a clear outline of nodal architecture. Intracellular fibronectin was observed in cases o...

journal_title：Journal of clinical pathology

authors： Reilly JT,Nash JR,Mackie MJ,McVerry BA

更新日期：1985-08-01 00:00:00

abstract：:Tests of iron and folate nutrition have been carried out in early pregnancy and at delivery in 63 Bantu females. Accepted normal values for serum iron, and percentage saturation of transferrin, but not for unsaturated iron-binding capacity, for non-pregnant subjects were found to apply equally well in pregnancy. Conco...

journal_title：Journal of clinical pathology

authors： Metz J,Turchetti L,Combrink B,Krawitz S

更新日期：1966-03-01 00:00:00

abstract：:Most patients with gonadoblastoma have dysgenetic gonads. This rare tumour has been described in three pregnant women. A fourth case in a 26 year old pregnant woman who presented with gonadoblastoma and dysgerminoma, is reported. She had a normal term pregnancy, 46XX chromosomes, normal genitalia, no history of menstr...

journal_title：Journal of clinical pathology

authors： Erhan Y,Toprak AS,Ozdemir N,Tiras B

更新日期：1992-09-01 00:00:00

abstract：:A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosi...

journal_title：Journal of clinical pathology

authors： Hann IM,Evans DI,Marsden HB,Jones PM,Palmer MK

更新日期：1978-04-01 00:00:00

abstract：AIMS:The generation and characterisation of a monoclonal antibody that specifically recognises the mdr-1 encoded protein, P-glycoprotein (P-170), on routinely processed formalin fixed, paraffin wax embedded tissue sections. METHODS:The monoclonal antibody, designated 6/1C, was produced following a combination of in vi...

journal_title：Journal of clinical pathology

authors： Moran E,Larkin A,Doherty G,Kelehan P,Kennedy S,Clynes M

更新日期：1997-06-01 00:00:00

abstract：:Visceral candidiasis in 56 patients, 39 of whom were thought to be immune deficient, was investigated using three serological detection methods--whole cell agglutination, haemagglutination, and counterimmunoelectrophoresis for antibodies; two determinations of circulating antigens--haemagglutination inhibition and lat...

journal_title：Journal of clinical pathology

authors： Platenkamp GJ,Van Duin AM,Porsius JC,Schouten HJ,Zondervan PE,Michel MF

更新日期：1987-10-01 00:00:00

abstract：AIM:An audit of serrated polyps diagnosed over a 4-year period: 2009 to 2012 was undertaken to ascertain the reporting trends of sessile serrated polyps (SSP). METHODS:All right sided hyperplastic polyps (HP) proximal to the splenic flexure and all polyps designated SSP were retrieved from the study period. Three path...

journal_title：Journal of clinical pathology

authors： Gill P,Wang LM,Bailey A,East JE,Leedham S,Chetty R

更新日期：2013-08-01 00:00:00

abstract：:Early epidemiological studies of cervical neoplasia suggested a causal relation with sexual activity and human papillomaviruses (HPVs) have emerged as prime suspects as venerally transmitted carcinogens. HPVs fall into two broad camps: low risk types, associated with cervical condylomas and CIN 1; and high risk types ...

journal_title：Journal of clinical pathology

authors： Arends MJ,Buckley CH,Wells M

更新日期：1998-02-01 00:00:00

abstract：AIMS:To investigate proliferative activity in leukaemic and lymphomatous bone marrow infiltrates and to assess the feasibility of transport of specimens among institutions. METHODS:Proliferative activity in bone marrow trephine cryosections from 99 patients with non-Hodgkin's lymphoma (NHL), 23 patients with acute mye...

journal_title：Journal of clinical pathology

authors： White DM,Smith AG,Smith JL

更新日期：1994-03-01 00:00:00

abstract：AIMS:To evaluate an antigen capture enzyme linked immunosorbent assay (ELISA) which detects a carbohydrate epitope on the excretory-secretory (ES) antigens of Toxocara canis in clinical practice. METHODS:Serum specimens from healthy adults, patients with acute visceral larva migrans, ocular and inactive toxocariasis, ...

journal_title：Journal of clinical pathology

authors： Gillespie SH,Bidwell D,Voller A,Robertson BD,Maizels RM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Hepatic fibrosis is one of the main consequences of liver disease. Both fibrosis and steatosis may be seen in some patients with chronic hepatitis C and alcoholic liver disease (ALD). AIMS:To quantitate fibrosis and steatosis by stereological and morphometric techniques in patients with chronic hepatitis C ...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,Al Mardini H,Awad S,Ukabam S,Makadisi S,Record CO

更新日期：2001-06-01 00:00:00