Reduced concentrations of selenium in mild Crohn's disease.

abstract：:A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

journal_title：Journal of clinical pathology

authors： Green NE

更新日期：1979-06-01 00:00:00

abstract：:Fluorescence in situ hybridisation (FISH) analysis is now widely employed in the diagnosis and risk stratification of a wide range of malignant diseases. While this technique is used successfully with formalin-fixed paraffin-embedded (FFPE) sections from numerous tissue types, FISH analysis of FFPE tissue sections fro...

journal_title：Journal of clinical pathology

authors： Neat MJ,Moonim MT,Dunn RG,Geoghegan H,Foot NJ

更新日期：2013-01-01 00:00:00

abstract：:Phyllodes tumours (PTs) of the breast are true biphasic neoplasms within which interactions between the epithelium and stroma are critical for tumour development and progression. Despite numerous studies reporting the results of ancillary marker investigations in PTs, the current histological grading systems remain un...

journal_title：Journal of clinical pathology

authors： Karim RZ,O'Toole SA,Scolyer RA,Cooper CL,Chan B,Selinger C,Yu B,Carmalt H,Mak C,Tse GM,Tan PH,Putti TC,Lee CS

更新日期：2013-06-01 00:00:00

abstract：AIMS:Iron overload is a major factor contributing to the overall pathology of thalassaemia, which is primarily mediated by ineffective erythropoiesis and shorter mature red blood cell (RBC) survival. Iron accumulation in RBCs generates reactive oxygen species (ROS) that cause cellular damage such as lipid peroxidation ...

journal_title：Journal of clinical pathology

authors： Chaichompoo P,Qillah A,Sirankapracha P,Kaewchuchuen J,Rimthong P,Paiboonsukwong K,Fucharoen S,Svasti S,Worawichawong S

更新日期：2019-08-01 00:00:00

abstract：:It was postulated that the short chain fatty acids (SCFA) produced by anaerobic bacteria might serve as microbial markers in purulent material. Eighteen pus specimens from various sources were analysed by gas-liquid chromatography (GLC), and the SCFA detected were compared with the microorganisms isolated by conventio...

journal_title：Journal of clinical pathology

authors： Ladas S,Arapakis G,Malamou-Ladas H,Palikaris G,Arseni A

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Inflammatory cells contribute to the growth and spread of human malignancies by producing molecules that enhance tumour invasiveness. AIMS:To characterise the inflammatory infiltrate in pancreatic ductal adenocarcinoma and to analyse its contribution to angiogenesis and its prognostic relevance. METHODS:Im...

journal_title：Journal of clinical pathology

authors： Esposito I,Menicagli M,Funel N,Bergmann F,Boggi U,Mosca F,Bevilacqua G,Campani D

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Hepatic fibrosis is one of the main consequences of liver disease. Both fibrosis and steatosis may be seen in some patients with chronic hepatitis C and alcoholic liver disease (ALD). AIMS:To quantitate fibrosis and steatosis by stereological and morphometric techniques in patients with chronic hepatitis C ...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,Al Mardini H,Awad S,Ukabam S,Makadisi S,Record CO

更新日期：2001-06-01 00:00:00

abstract：:The role of active hepatitis B virus (HBV) infection in chronic HBsAg positive hepatitis with and without hepatitis delta virus (HDV) superinfection was analysed in percutaneous liver biopsy specimens from 50 patients. Each specimen was divided into two--one part for histological evaluation and for the detection of HB...

journal_title：Journal of clinical pathology

authors： Villari D,Raimondo G,Smedile V,Rodinó G,Brancatelli S,Longo G,Squadrito G,Batolo D

更新日期：1989-07-01 00:00:00

abstract：:The mucin and gland content of 26 rectal biopsy specimens--five normal specimens, 10 from patients with ulcerative colitis, and 11 from patients with Crohn's disease--were measured using a Quantimet image analyser. There was significantly less mucin in the groups with ulcerative colitis compared with either those with...

journal_title：Journal of clinical pathology

authors： McCormick DA,Horton LW,Mee AS

更新日期：1990-02-01 00:00:00

abstract：:Several DNA extraction techniques were quantitatively and qualitatively compared using both fresh and paraffin wax embedded tissue and their suitability investigated for providing DNA and RNA for the polymerase chain reaction (PCR). A one hour incubation with proteinase K was the most efficient DNA extraction procedur...

journal_title：Journal of clinical pathology

authors： Jackson DP,Lewis FA,Taylor GR,Boylston AW,Quirke P

更新日期：1990-06-01 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：:This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass. ...

journal_title：Journal of clinical pathology

authors： Horwood E,Dowson H,Gupta R,Kaczmarski R,Williamson M

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori associated gastric cancer arises via a multistage process, with atrophic gastritis being the precursor lesion. Helicobacter pylori is typically acquired in childhood, yet little is known of the prevalence of atrophic gastritis in childhood. AIM:To study atrophic gastritis among children ...

journal_title：Journal of clinical pathology

authors： Ricuarte O,Gutierrez O,Cardona H,Kim JG,Graham DY,El-Zimaity HM

更新日期：2005-11-01 00:00:00

abstract：:A 60 year old woman affected by Hashimoto's thyroiditis presented with a history of recurring episodes of urticaria and angio-oedema. Clinical and laboratory evaluation of the patient excluded allergy to external agents, hereditary angio-oedema, and occult infections. A pathogenic relation between Hashimoto's thyroidi...

journal_title：Journal of clinical pathology

authors： Amoroso A,Garzia P,Pasquarelli C,Sportelli G,Afeltra A

更新日期：1997-03-01 00:00:00

abstract：:The aim of this article is to provide knowledge of the origin of catecholamines and metabolites so that there can be an informed approach to the methods for biochemical screening for a possible phaeochromocytoma; The article includes a review of catecholamine and metadrenaline metabolism, with methods used in biochemi...

journal_title：Journal of clinical pathology

authors： Barron J

更新日期：2010-08-01 00:00:00

abstract：AIMS:Acute traumatic coagulopathy is characterised by fibrinolysis and low fibrinogen. It is unclear how much fibrinogenolysis contributes to reduce fibrinogen levels. The study aim was to: investigate in vitro the effects of tissue-plasminogen activator (t-PA) and tranexamic acid (TXA) on coagulation and fibrinolysis....

journal_title：Journal of clinical pathology

authors： Godier A,Parmar K,Manandhar K,Hunt BJ

更新日期：2017-02-01 00:00:00

abstract：:Methods for detecting insulin binding or transporting antibodies are described, involving the use of radioactively labelled insulin (insulin (131)I). These antibodies are detected in a high proportion of patients receiving insulin, particularly those requiring large doses. The protein fractions concerned appear to be ...

journal_title：Journal of clinical pathology

authors： HARRIS-JONES JN,MILLER H,OWEN G

更新日期：1963-03-01 00:00:00

abstract：:Antithrombin activities in 30 severely malnourished children and 40 normal children were estimated in clotting tests by thrombin neutralisation as anti-Xa and by a heparin antithrombin assay; and by immunodiffusion as alpha 2-globulin and alpha 1-antitrypsin. The patients' mean alpha 2-globulin was severely depressed,...

journal_title：Journal of clinical pathology

authors： Jiménez RA,Jiménez E,Ingram GI,Mora LA,Atmetlla F,Carrillo JM,Vargas W

更新日期：1979-10-01 00:00:00

abstract：AIMS:The localisation of the translocation breakpoint of the Ewing sarcoma family of tumours shows significant variability on relatively large regions of fusion partner genes. As a consequence, many alternative forms of EWSR1-ETS translocation exist which make the RNA-based molecular diagnostics of Ewing sarcoma family...

journal_title：Journal of clinical pathology

authors： Patócs B,Németh K,Garami M,Arató G,Kovalszky I,Szendroi M,Fekete G

更新日期：2012-12-01 00:00:00

abstract：:Autoantibodies against gastric epithelial cells are detectable in up to 50% of patients with chronic, active Helicobacter pylori gastritis. Presence of autoantibodies against canalicular structures within human parietal cells (anticanalicular autoantibodies) correlate with gastric mucosa atrophy. It has been suggested...

journal_title：Journal of clinical pathology

authors： Faller G,Steininger H,Appelmelk B,Kirchner T

更新日期：1998-03-01 00:00:00

abstract：:Hereditary breast cancer accounts for up to 5-10% of all breast carcinomas. Recent studies have demonstrated that mutations in two high-penetrance genes, namely BRCA1 and BRCA2, are responsible for about 16% of the familial risk of breast cancer. Even though subsequent studies have failed to find another high-penetran...

journal_title：Journal of clinical pathology

authors： Tan DS,Marchiò C,Reis-Filho JS

更新日期：2008-10-01 00:00:00

abstract：:An enzyme linked immunoadsorbent assay (ELISA) was used to detect IgG, IgM, and IgA antibody in urine to a crude antigenic mixture prepared from six arbitrarily chosen strains of common coliform urinary pathogens. In a group of patients with symptoms of urinary tract infection 24 of 80 (30%) urine samples were positiv...

journal_title：Journal of clinical pathology

authors： McKenzie H,Young DN

更新日期：1987-07-01 00:00:00

abstract：:A case of florid rheumatoid heart disease with complete heart block is described, and the histopathology of the atrioventricular conducting tissue is described in detail. ...

journal_title：Journal of clinical pathology

authors： Harris M

更新日期：1970-10-01 00:00:00

abstract：:In two out of three cases of idiopathic fibrosis of the mediastinum there was also retroperitoneal fibrosis, and in one of them extensive fibrosis of the lungs. One of these, a fit middle-aged man, died suddenly with severe coronary artery stenosis due to fibrosis. The third case was that of a young man with a solitar...

journal_title：Journal of clinical pathology

authors： Light AM

更新日期：1978-01-01 00:00:00

abstract：AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...

journal_title：Journal of clinical pathology

authors： González MV,Pello MF,López-Larrea C,Suárez C,Menéndez MJ,Coto E

更新日期：1997-06-01 00:00:00

abstract：:The cell volumes of mononuclear cells, T lymphocytes, B lymphocytes, and monocytes from the peripheral blood of 20 normal individuals were compared to neoplastic lymphoid cells from 14 patients with chronic lymphocytic leukaemia (CLL), 20 individuals with acute lymphocytic leukaemia (ALL), and 18 cases of non-Hodgkin'...

journal_title：Journal of clinical pathology

authors： Chapman EH,Kurec AS,Davey FR

更新日期：1981-10-01 00:00:00

abstract：:Of 30 children with bleeding disorders exposed to an index tuberculosis case, six developed primary pulmonary tuberculosis and two others became positive skin reactors. There was a significant correlation between the amount of replacement treatment received and the development of evidence of tuberculous infection. Onl...

journal_title：Journal of clinical pathology

authors： Beddall AC,Hill FG,George RH,Williams MD,Al-Rubei K

更新日期：1985-10-01 00:00:00

abstract：AIM:To compare the sensitivity and staining pattern of the new immunohistochemical antibody to tyrosinase (T311) with S-100, HMB45, and the recently evaluated antibody to melan-A (A103) in a range of melanocytic lesions. METHOD:Archival, formalin fixed, paraffin wax embedded sections from 50 benign and malignant melan...

journal_title：Journal of clinical pathology

authors： Clarkson KS,Sturdgess IC,Molyneux AJ

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The "classical" antineutrophil cytoplasmic antibody (C-ANCA) pattern seen on indirect immunofluorescence (IIF) is characterised by granular cytoplasmic staining showing central or interlobular accentuation, and is strongly associated with antiproteinase-3 antibodies (PR3-ANCA) and Wegener's granulomatosis. H...

journal_title：Journal of clinical pathology

authors： Wong RC,Silvestrini RA,Savige JA,Fulcher DA,Benson EM

更新日期：1999-02-01 00:00:00

abstract：:Human papillomavirus (HPV) infection of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma was investigated using in situ DNA-DNA hybridisation on histological sections of formalin fixed, paraffin embedded tissue to assess the technique's sensitivity and to assess retrospectively the association ...

journal_title：Journal of clinical pathology

authors： Collins JE,Jenkins D,McCance DJ

更新日期：1988-03-01 00:00:00