Diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay.

Abstract:

AIMS:To evaluate an antigen capture enzyme linked immunosorbent assay (ELISA) which detects a carbohydrate epitope on the excretory-secretory (ES) antigens of Toxocara canis in clinical practice. METHODS:Serum specimens from healthy adults, patients with acute visceral larva migrans, ocular and inactive toxocariasis, and with other helminth infections were examined by two site antigen capture ELISA. RESULTS:Over half of the patients (19/28) with acute toxocariasis had a positive result in contrast to a small proportion of those with inactive disease (1/10) or ocular infection (2/7). False positive reactions, however, were found in 25% of the patients with serologically confirmed schistosomiasis and filariasis. CONCLUSIONS:This assay is useful in confirming the diagnosis of acute visceral larva migrans but could not be used alone in diagnosis because of false positive reactions in patients with other helminth infections.

journal_name

J Clin Pathol

authors

Gillespie SH,Bidwell D,Voller A,Robertson BD,Maizels RM

doi

10.1136/jcp.46.6.551

subject

Has Abstract

pub_date

1993-06-01 00:00:00

pages

551-4

issue

6

eissn

0021-9746

issn

1472-4146

journal_volume

46

pub_type

杂志文章
  • Aplastic anaemia associated with organochlorine pesticide: case reports and review of evidence.

    abstract::Three patients with aplastic anaemia had a history of substantial previous exposure to organochlorine pesticides. The temporal association between chemical exposure and the onset of first symptoms of anaemia was strongly supportive. Organochlorines have the property of lipid affinity and accumulation in adipose tissue...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.43.2.98

    authors: Rugman FP,Cosstick R

    更新日期:1990-02-01 00:00:00

  • Corticosteroids as adjunctive treatment in Austrian's syndrome (pneumococcal endocarditis, meningitis, and pneumonia): report of two cases and review of the literature.

    abstract::This report describes two cases of Osler's triad of pneumonia, meningitis, and endocarditis, as a result of Streptococcus pneumoniae infection, also called Austrian's syndrome. In the first patient, a 51 year old non-alcoholic man, the aortic valve was affected and needed to be replaced in an emergency operation. The ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1136/jcp.56.11.879

    authors: du Cheyron D,Lesage A,Le Page O,Flais F,Leclercq R,Charbonneau P

    更新日期:2003-11-01 00:00:00

  • Malignant hyperpyrexia: a rare cause of postoperative death.

    abstract::A middle aged man developed very high fever, status epilepticus, and terminal acute renal failure with myoglobinuria after surgery. A post mortem examination showed widespread muscle necrosis with hypercontraction bands. Muscle enzyme studies and electron microscopic examination disclosed central core disease, a condi...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.45.4.361

    authors: Prescott RJ,Roberts SP,Williams G

    更新日期:1992-04-01 00:00:00

  • Kawasaki disease, Epstein-Barr virus and coronary artery aneurysms.

    abstract:AIM:To establish whether infection with Epstein-Barr virus (EBV) contributed to the development of coronary artery lesions in a six year old child with an aneurysm and stenoses of the coronary arteries and suspected Kawasaki disease. METHODS:Postmortem paraffin wax sections of the coronary artery and myocardium were e...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.50.2.161

    authors: Culora GA,Moore IE

    更新日期:1997-02-01 00:00:00

  • Fatal renal failure as the first manifestation of sarcoidosis diagnosed on necropsy in a young man: a case report.

    abstract::Renal involvement as the first manifestation of sarcoidosis is rare and has never been reported in India. This report describes a 35 year old man who was admitted to the emergency department with a clinical diagnosis of acute on chronic renal failure, secondary to obstructive uropathy. Postmortem examination unexpecte...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,评审

    doi:10.1136/jcp.2004.018325

    authors: Awasthi A,Nada R,Malhotra P,Goel R,Joshi K

    更新日期:2004-10-01 00:00:00

  • A literary portrait of a case of Hodgkin lymphoma by Wilkie Collins?

    abstract::In October 1859, 'The Queen of Hearts' was published by Wilkie Collins. This book is a collection of 10 short stories written by the protagonists (three retired brothers), in order to keep their niece (aka the queen of hearts) entertained, until the arrival of her fiancé-to-be. The second story of the book, titled 'Br...

    journal_title:Journal of clinical pathology

    pub_type: 历史文章,杂志文章

    doi:10.1136/jcp.2010.085571

    authors: Fernandez-Flores A

    更新日期:2011-02-01 00:00:00

  • AN ANTIBODY AGAINST STORED BLOOD ASSOCIATED WITH CIRRHOSIS OF THE LIVER AND FALSE-POSITIVE SEROLOGICAL TESTS FOR SYPHILIS.

    abstract::A case of cirrhosis of the liver, associated with false-positive serological tests for syphilis and an antibody active against stored red cells, is presented. Methods used in the identification of the ;stored red cell' antibody are described. ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.18.4.460

    authors: EASTON JA,PRIEST CJ,GILES CM

    更新日期:1965-07-01 00:00:00

  • Evaluation of sensitivity of 10 diagnostic assays for Chlamydia trachomatis by use of a simple laboratory procedure.

    abstract:AIMS:To determine the sensitivity of commercially available diagnostic assays for Chlamydia trachomatis using a simple method. METHODS:Nine commercial assays and an "in-house" polymerase chain reaction (PCR) were evaluated using serial dilutions of a laboratory grown H serovar--four of them using a laboratory grown E ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.46.5.408

    authors: Thomas BJ,MacLeod EJ,Taylor-Robinson D

    更新日期:1993-05-01 00:00:00

  • Lymphocytic sialadenitis in the major and minor glands: a correlation in postmortem subjects.

    abstract::In the present investigation, the prevalence of focal lymphocytic adenitis in the submandibular salivary gland was observed in a series of 116 postmortem subjects after suitable exclusions had been made. Focal lymphocytic adenitis could not be demonstrated in the labial salivary glands. The degree of lymphocytic infil...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.23.8.690

    authors: Chisholm DM,Waterhouse JP,Mason DK

    更新日期:1970-11-01 00:00:00

  • A case of IgD myeloma presenting as diffuse osteosclerosis.

    abstract::A case of IgD myeloma accompanied by diffuse osteosclerosis is reported. A trephine biopsy specimen showed only reticulin fibrosis, but histomorphometric analysis of a full thickness transiliac bone biopsy specimen showed increased trabecular bone mass, with no local deposit of tumour. An excess of bone surfaces were ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.41.5.486

    authors: MacCallum PK,Freemont AJ,Geary CG,Liu Yin JA

    更新日期:1988-05-01 00:00:00

  • Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes.

    abstract:AIMS/BACKGROUND:Telomerase, an enzyme associated with cellular immortality, is expressed by most malignant tumours, but is inactive in normal somatic cells except for male germ cells and proliferating stem cells. Thus, the measurement of telomerase activity in tissue samples may provide useful diagnostic and prognostic...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.50.2.110

    authors: Yashima K,Piatyszek MA,Saboorian HM,Virmani AK,Brown D,Shay JW,Gazdar AF

    更新日期:1997-02-01 00:00:00

  • Splitting bone marrow trephines into frozen and fixed fragments allows parallel histological and molecular detection of B cell malignant infiltrates.

    abstract::Clonality analysis of the immunoglobulin heavy chain (IgH) gene is helpful in identifying malignant B cell infiltrates in the bone marrow and is usually carried out on separate aspirates or on the same formalin-fixed decalcified bone marrow specimen. To determine whether the removal of the decalcification step would i...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.2005.030379

    authors: Parrens M,Carrere N,Bouabdallah K,Fitoussi O,Goussot JF,Dubus P,de Mascarel A,Merlio JP

    更新日期:2006-10-01 00:00:00

  • Mucin depletion in inflammatory bowel disease.

    abstract::The mucin and gland content of 26 rectal biopsy specimens--five normal specimens, 10 from patients with ulcerative colitis, and 11 from patients with Crohn's disease--were measured using a Quantimet image analyser. There was significantly less mucin in the groups with ulcerative colitis compared with either those with...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.43.2.143

    authors: McCormick DA,Horton LW,Mee AS

    更新日期:1990-02-01 00:00:00

  • A modified rapid slide test for anti-streptolysin O.

    abstract::This paper describes the modification of a commercially available rapid slide screening test(1) for anti-streptolysin O to give quantitative results. The modified technique is compared with the long-established haemolytic technique of Rantz and Randall (1945). The quantitative results for both techniques are shown to ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.25.6.543

    authors: Ingram GB,Hughes JE

    更新日期:1972-06-01 00:00:00

  • Laboratory diagnosis of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis.

    abstract::A simple laboratory method for culture of continuous ambulatory peritoneal dialysis (CAPD) fluids is described. Guidelines for antimicrobial therapy are discussed based on results from 18 patients studied over an 11-week period. Cephalosporins appeared to be a rational choice for therapy while awaiting laboratory resu...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.35.11.1181

    authors: Fenton P

    更新日期:1982-11-01 00:00:00

  • Cryptal lymphocytic coloproctitis: a new phenotype of lymphocytic colitis?

    abstract:BACKGROUND/AIMS:Lymphocytic colitis is a clinicopathological entity characterised by protracted watery diarrhoea and an increased number of intraepithelial lymphocytes (IELs) in the surface epithelium of the colonic mucosa. This report describes two patients with symptoms similar to those of lymphocytic colitis and an ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.55.2.138

    authors: Rubio CA,Lindholm J

    更新日期:2002-02-01 00:00:00

  • Atypical hyperplasia in prostates of 20 to 40 year old men.

    abstract::One hundred prostates from 20 to 40 year old men obtained at necropsy were completely sectioned and studied microscopically. Atypical hyperplasia was found in 10 (20%) of 20-29 year old men and in 12 (24%) of 30-40 year old men. The prostates with atypical hyperplasia had similar weights as those without, and the atyp...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.42.4.383

    authors: Brawn PN,Speights VO,Contin JU,Bayardo RJ,Kuhl DL

    更新日期:1989-04-01 00:00:00

  • Faecal haemoglobin concentration is related to severity of colorectal neoplasia.

    abstract:AIMS:Guaiac faecal occult blood tests are being replaced by faecal immunochemical tests (FIT). We investigated whether faecal haemoglobin concentration (f-Hb) was related to stage in progression of colorectal neoplasia, studying cancer and adenoma characteristics in an evaluation of quantitative FIT as a first-line scr...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jclinpath-2013-201445

    authors: Digby J,Fraser CG,Carey FA,McDonald PJ,Strachan JA,Diament RH,Balsitis M,Steele RJ

    更新日期:2013-05-01 00:00:00

  • Effect of new plastics and leucocyte contamination on in vitro storage of platelet concentrates.

    abstract::Platelet concentrates were prepared for in vitro storage in either Fenwal PL-732 or Cutter CLX platelet packs. The units were stored at 22 degrees C for seven days with either horizontal or tumbler agitation. Measurement of pH, hypotonic shock response and serotonin uptake indicated in vitro viability was well maintai...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.36.12.1382

    authors: Taylor MA,Tandy NP,Fraser ID

    更新日期:1983-12-01 00:00:00

  • Distinction between aleukaemic prodrome of childhood acute lymphoblastic leukaemia and aplastic anaemia.

    abstract:AIMS:To document the features of the so-called aplastic presentation of childhood acute lymphoblastic leukaemia (ALL) and to determine whether this prodrome can be distinguished from aplasia. METHODS:The peripheral blood and bone marrow appearances of all cases of childhood ALL presenting in one health region of Engla...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.45.8.697

    authors: Reid MM,Summerfield GP

    更新日期:1992-08-01 00:00:00

  • Helicobacter pylori infection in patients with Barrett's oesophagus: a prospective immunohistochemical study.

    abstract::The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barr...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.49.2.176

    authors: Ricaurte O,Fléjou JF,Vissuzaine C,Goldfain D,Rotenberg A,Cadiot G,Potet F

    更新日期:1996-02-01 00:00:00

  • Alpha-hydroxybutyrate dehydrogenase activity in sex-linked muscular dystrophy.

    abstract::In two families with severe sex-linked muscular dystrophy, high levels of alpha-hydroxybutyrate dehydrogenase (HBD), lactate dehydrogenase (LD), aspartate transaminase (AspT), aldolase, and creatine phosphokinase (CPK) were found in the sera of three young affected males. In both families the mother had a raised level...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.19.3.250

    authors: Johnston HA,Wilkinson JH,Withycombe WA,Raymond S

    更新日期:1966-05-01 00:00:00

  • Urinary cyclic adenosine monophosphate in young adults and elderly subjects.

    abstract::The 24-hour urinary excretion of cyclic 3',5'-adenosine monophosphate (cAMP) was measured by a protein-binding assay in 55 healthy volunteers (aged 20-35 yr) and in 30 hospitalized elderly subjects (aged 70-93 yr). In the older subjects the mean 24-hour cAMP excretion was significantly lower; the correlation between c...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.29.1.69

    authors: Gennari C,Galli M,Montagnani M

    更新日期:1976-01-01 00:00:00

  • Aminoglycoside antibiotics and renal function: changes in urinary gamma-glutamyltransferase excretion.

    abstract::The urinary excretion of the renal proximal tubular enzyme, gamma-glutamyltransferase (gamma-GT), has been studied in 41 patients receiving tobramycin, gentamicin or streptomycin for a variety of infections. All patients receiving tobramycin or gentamicin have shown increased excretion of gamma-GT in the urine. Only 4...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.30.5.432

    authors: Beck PR,Thomson RB,Chaudhuri AK

    更新日期:1977-05-01 00:00:00

  • Benefits of costing in the clinical laboratory.

    abstract::This paper urges the benefits of applying more widely a method for pathology laboratory costing originally devised for a clinical chemistry department, and illustrates these with examples drawn from costing studies in three clinical laboratories. Heads of pathology departments, laboratory managers, administrators and ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.36.9.1028

    authors: Broughton PM,Woodford FP

    更新日期:1983-09-01 00:00:00

  • Cell volumes of normal and malignant mononuclear cells.

    abstract::The cell volumes of mononuclear cells, T lymphocytes, B lymphocytes, and monocytes from the peripheral blood of 20 normal individuals were compared to neoplastic lymphoid cells from 14 patients with chronic lymphocytic leukaemia (CLL), 20 individuals with acute lymphocytic leukaemia (ALL), and 18 cases of non-Hodgkin'...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.34.10.1083

    authors: Chapman EH,Kurec AS,Davey FR

    更新日期:1981-10-01 00:00:00

  • Presence of vascular adventitial fibroblastic cells in diffuse-type gastric carcinomas.

    abstract:AIM:To investigate morphological changes in the tumour vessel adventitia, particularly the distribution of vascular adventitial fibroblastic cells (VAFCs)--namely, CD34 positive fibroblastic cells just outside the vascular media--in diffuse-type gastric carcinomas. METHOD:In total, 18 surgically resected advanced typi...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.2004.017137

    authors: Nakayama H,Enzan H,Miyazaki E,Kuroda N,Toi M,Hiroi M,Yasui W

    更新日期:2004-09-01 00:00:00

  • Beta-propiolactone as an agent for enzyme sterilization.

    abstract::A chemical method for the sterilization of pancreatin and trypsin is given. Evidence is presented to show that this treatment does not diminish the specific activity of the enzymes and has some advantages in microbiological techniques. ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.24.7.658

    authors: Stokes KJ

    更新日期:1971-10-01 00:00:00

  • Mercury sensitivity of staphylococci.

    abstract::The technique devised by Moore (1960) for determining the sensitivity of staphylococci to mercuric chloride was investigated and the effect of variations in the medium determined. An alternative technique, in which paper discs impregnated with phenyl mercuric nitrate are used, was found to give identical results. Thre...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.15.3.249

    authors: GREEN SM

    更新日期:1962-05-01 00:00:00

  • Detection and typing of human papillomaviruses in mucosal and cutaneous biopsies from immunosuppressed and immunocompetent patients and patients with epidermodysplasia verruciformis: a unified diagnostic approach.

    abstract:AIM:To develop a unified diagnostic approach for the detection of human papillomavirus (HPV) DNA in skin and mucosal biopsies from both immunocompetent and immunosuppressed individuals using a degenerate polymerase chain reaction (PCR) method. METHODS:The sensitivity and specificity of three published degenerate prime...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章

    doi:10.1136/jcp.51.8.606

    authors: Surentheran T,Harwood CA,Spink PJ,Sinclair AL,Leigh IM,Proby CM,McGregor JM,Breuer J

    更新日期:1998-08-01 00:00:00