Autoimmune markers are undetectable in end stage idiopathic dilated cardiomyopathy.

abstract：:Sixty-nine specimens of liver tissue from 53 infants with neonatal hepatitis or its sequelae were examined without knowledge of the alpha1-antitrypsin phenotype. Distinctive, diastase-resistant, PAS-positive, pure magenta-coloured, sharply defined globules, 2-20 microns in diameter were found in periportal and parasep...

journal_title：Journal of clinical pathology

authors： Talbot IC,Mowat AP

更新日期：1975-07-01 00:00:00

abstract：:A 43-year-old man, admitted with a swollen right thigh, was diagnosed with a deep vein thrombosis. On day 6 he became septic. A CT scan demonstrated a right-sided hydronephrosis and a large retroperitoneal collection. Blood cultures and perinephric pus grew Escherichia coli resistant to amoxicillin only. On day 12 a v...

journal_title：Journal of clinical pathology

authors： Alleyne SA,Bukhari SS,Fraser M,Spiers P

更新日期：2010-04-01 00:00:00

abstract：AIMS:To investigate the histopathological changes in the livers of patients undergoing cholecystectomy and to relate these changes to the underlying biliary tract pathology. METHODS:Liver changes in 67 patients undergoing cholecystectomy were investigated. Sixty three had gall stones, one cholesterolosis only, and the...

journal_title：Journal of clinical pathology

authors： Geraghty JM,Goldin RD

更新日期：1994-05-01 00:00:00

abstract：AIMS/BACKGROUND:A major medical role for postmortem examinations is the detection of clinically unexpected disease processes contributing to death. The aim of the present study was to determine whether simple clinical parameters can predict the presence of important unanticipated findings at necropsy. METHODS:Prospect...

journal_title：Journal of clinical pathology

authors： Robinson IA,Marley NJ

更新日期：1996-11-01 00:00:00

abstract：AIM:Recent events surrounding postmortem practices have necessitated several changes in the way necropsies are conducted both within the medicolegal and hospital settings. These changes have resulted in a striking reduction in the frequency of brain retention for neuropathological examination. Aberdeen Royal Infirmary,...

journal_title：Journal of clinical pathology

authors： Sharma M,Grieve JH

更新日期：2006-04-01 00:00:00

abstract：:The case records and pathology of all children with kidney tumours treated in the West Midlands Health Authority Region (WMHAR) from 1957 to 1986 were reviewed. The histology was reviewed by a panel of three paediatric pathologists. Thirteen (6%) out of 211 cases were considered to have congenital mesoblastic nephroma...

journal_title：Journal of clinical pathology

authors： Barrantes JC,Toyn C,Muir KR,Parkes SE,Raafat F,Cameron AH,Marsden HB,Mann JR

更新日期：1991-04-01 00:00:00

abstract：:Serum glycocholic acid (SGC) was measured by radioimmunoassay in 277 samples from 122 children with hepatobiliary disorders and from 23 healthy age-matched controls. In patients with hepatobiliary disease the SGC was more frequently abnormal (83%) than values for serum albumin (7%), prothrombin time (17%), bilirubin (...

journal_title：Journal of clinical pathology

authors： Matsui A,Psacharopoulos HT,Mowat AP,Portmann B,Murphy GM

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Currently, no specific immunohistochemical markers are available to differentiate primary mucinous epithelial ovarian cancer (MOC) from adenocarcinomas originating at other sites that have metastasised to the ovary, which may have an impact on patient management and prognosis. AIM:To investigate the express...

journal_title：Journal of clinical pathology

authors： Heinzelmann-Schwarz VA,Scolyer RA,Scurry JP,Smith AN,Gardiner-Garden M,Biankin AV,Baron-Hay S,Scott C,Ward RL,Fink D,Hacker NF,Sutherland RL,O'Brien PM

更新日期：2007-06-01 00:00:00

abstract：AIMS:To investigate the genetic differences among the strains of adenovirus type 8 (Ad8) circulating in Hiroshima city, Japan, and to study their circulation pattern. METHODS:One hundred and twenty nine strains of adenovirus type 8 (Ad8) were isolated in Hiroshima City over a 15 year period (1983-97) from patients wit...

journal_title：Journal of clinical pathology

authors： Adhikary AK,Numaga J,Kaburaki T,Kawashima H,Araie M,Ikeda Y,Ogino T,Suzuki E,Ushijima H,Mukoyama A,Matsuno S,Inada T,Okabe N

更新日期：2003-02-01 00:00:00

abstract：:A rare case of adult onset Langerhans' cell histiocytosis associated with dysgerminoma in a 35 year old Chinese woman is reported. The patient had a history of dysgerminoma of left ovary 15 years previously and had undergone surgery followed by radiotherapy and an uneventful recovery. She presented again in March 1994...

journal_title：Journal of clinical pathology

authors： Ng WK,Lam KY,Ng IO

更新日期：1995-10-01 00:00:00

abstract：:A competitive enzyme linked immunosorbent assay (ELISA) method was used to measure the concentration of lactoferrin in fluids from 36 odontogenic keratocysts, 15 dentigerous cysts, and 30 radicular/residual cysts. Keratocyst fluids contained significantly higher concentrations of lactoferrin than fluids from the other...

journal_title：Journal of clinical pathology

authors： Douglas CW,Craig GT

更新日期：1989-02-01 00:00:00

abstract：:Malignant histiocytosis (histiocytic medullary reticulosis) in a 45-year-old white man is described. Unusual features were presentation as a surgical emergency with signs of obstruction and peritonitis due to an ileal tumour and extensive spindle cell differentiation. Problems in the differential diagnosis of malignan...

journal_title：Journal of clinical pathology

authors： Macgillivray JB,Duthie JS

更新日期：1977-02-01 00:00:00

abstract：:Three strains of Past. septica were isolated in Hong Kong. The clinical histories and the detailed bacteriological and serological studies are presented. ...

journal_title：Journal of clinical pathology

authors： WONG PC,CHAN-TEOH CH

更新日期：1964-03-01 00:00:00

abstract：AIMS:Most benign breast fibroepithelial lesions (FEL) in adults harbour recurrent somatic MED12 exon 2 mutations and rare TERT promoter hotspot mutations. We sought to determine the frequency of MED12 exon 2 and TERT promoter hotspot mutations in fibroadenomas (FA) and benign phyllodes tumours (BePT) in adolescents and...

journal_title：Journal of clinical pathology

authors： Pareja F,Da Cruz Paula A,Murray MP,Hoang T,Gularte-Mérida R,Brown D,da Silva EM,Sebastiao APM,Giri DD,Weigelt B,Reis-Filho JS,Brogi E

更新日期：2019-03-01 00:00:00

abstract：:The relationship between the intensity of the delayed hypersensitivity reaction and the dose of antigen used for its elicitation change with time after sensitization. At three weeks the reactions to 100 mug of egg albumen were little different from those to 1 mug but at 14 weeks 100 mug gave much stronger reactions. T...

journal_title：Journal of clinical pathology

authors： Jokipii AM,Jokipii L

更新日期：1973-09-01 00:00:00

abstract：:Improvements in the Zimmermann reaction are effected by using methanol as a solvent for the reagents employed in the reaction in place of ethanol or aqueous ethanol. The advantages are as follows. Considerably lower blanks are obtained; extraneous chromogens are negligible at the wavelength of measurement, so that no ...

journal_title：Journal of clinical pathology

authors： BEALE RN,BOSTROM JO,CROFT D

更新日期：1962-11-01 00:00:00

abstract：:Expression profiling has been extensively applied to the study of breast cancer and undoubtedly is changing the way breast cancer is perceived. Over the past few years, several groups have described prognostic "signatures" (gene lists) that are purported to be more accurate prognostic factors than well established cli...

journal_title：Journal of clinical pathology

authors： Reis-Filho JS,Westbury C,Pierga JY

更新日期：2006-03-01 00:00:00

abstract：:A large body of evidence supports the idea that certain adult stem cells, particularly those of bone marrow origin, can engraft at alternative locations, particularly when the recipient organ is damaged. Under strong and positive selection pressure these cells will clonally expand/differentiate, making an important co...

journal_title：Journal of clinical pathology

authors： Alison MR,Poulsom R,Otto WR,Vig P,Brittan M,Direkze NC,Lovell M,Fang TC,Preston SL,Wright NA

更新日期：2004-02-01 00:00:00

abstract：AIMS:Apoptosis in prostate cancer was evaluated after three months of combined endocrine therapy to investigate the association with tumour grade, tumour stage, and the immunohistochemical detection of p53 and bcl-2 in tumour cells before and after therapy. METHODS:Twenty six formalin fixed, paraffin wax embedded core...

journal_title：Journal of clinical pathology

authors： Colecchia M,Frigo B,Del Boca C,Guardamagna A,Zucchi A,Colloi D,Leopardi O

更新日期：1997-05-01 00:00:00

abstract：AIMS:Ki-67 is a prognostic marker in breast cancer; however, the use of the Ki-67 labelling index (LI) in clinical practice requires a consistent and easily accessible scoring method. The present study evaluated the use of the free internet-based image analysis program ImmunoRatio to score Ki-67 LI in breast cancer in ...

journal_title：Journal of clinical pathology

authors： Yeo MK,Kim HE,Kim SH,Chae BJ,Song BJ,Lee A

更新日期：2017-08-01 00:00:00

abstract：AIMS:Venous invasion (VI) is a known independent prognostic indicator of recurrence and survival in colorectal cancer. The guidelines of the Royal College of Pathologists (RCPath) state that, in a series of resections, extramural VI should be detected in at least 25% of specimens. However, there is widespread variabili...

journal_title：Journal of clinical pathology

authors： Messenger DE,Driman DK,McLeod RS,Riddell RH,Kirsch R

更新日期：2011-11-01 00:00:00

abstract：:The sensitivity of an indirect immunofluorescence antibody test (IFAT) and a rapid microagglutination test (RMAT) for the diagnosis of Legionnaires' disease caused by Legionella pneumophila serogroup 1 was evaluated using serum specimens from 119 patients with bacteriologically confirmed infections. The sensitivity of...

journal_title：Journal of clinical pathology

authors： Harrison TG,Dournon E,Taylor AG

更新日期：1987-01-01 00:00:00

abstract：CLINICAL QUESTION:A 77-year-old man presented with haematuria. Cystoscopy revealed a papillary tumour in the trigone region of the bladder. A TURBT was performed. Review the high-quality, interactive digital Aperio slide at http://virtualacp.com/JCPCases/jclinpath-2016-204015 and consider your diagnosis. WHAT IS YOUR D...

journal_title：Journal of clinical pathology

authors： Trefor R,Varma M

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Cutaneous squamous cell carcinoma (cSCC) is the second most common malignancy, most frequently affecting the head and neck. Treatment often requires surgery and can have significant functional morbidity. Research into disease pathogenesis and second line medical management of cSCC is limited. We assess geneti...

journal_title：Journal of clinical pathology

authors： Zilberg C,Lee MW,Kraitsek S,Ashford B,Ranson M,Shannon K,Iyer NG,Ch'ng S,Low TH,Palme C,Clark J,Gupta R,Yu B

更新日期：2020-01-01 00:00:00

abstract：:A 45-year-old man is described in whom there is currently ERCP and histological evidence of primary sclerosing cholangitis (PSC). A liver biopsy obtained 29 years ago shows similar histological features confirming that he had PSC at that time. This case indicates that PSC may follow a relatively benign course. ...

journal_title：Journal of clinical pathology

authors： Goudie BM,Birnie GG,Watkinson G,MacSween RN

更新日期：1983-11-01 00:00:00

abstract：AIM:To evaluate the sources of fetal haemoglobin (HbF) as an indicator in cancer. An immunohistochemical study was carried out on some of the most common kinds of cancer. All of these cancers had serologically high levels of HbF as evaluated previously. METHODS:Immunoaffinity-purified anti-HbF was immunohistochemicall...

journal_title：Journal of clinical pathology

authors： Wolk M,Martin JE,Reinus C

更新日期：2006-06-01 00:00:00

abstract：AIM:To assess the topographical relation between gastric glands, using the minimum spanning tree (MST), to derive both a model of neighbourhood and quantitative representation of the tissue's architecture, to assess the characteristic features of gastric atrophy, and to assess the grades of gastric atrophy. METHODS:Ha...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,al Mardini H,Record CO

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:EpCAM is an adhesion molecule of the basolateral membranes in a variety of epithelial cells. Over-expression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. AIMS:To assess the prognostic value of EpCAM in urothelial ...

journal_title：Journal of clinical pathology

authors： Brunner A,Prelog M,Verdorfer I,Tzankov A,Mikuz G,Ensinger C

更新日期：2008-03-01 00:00:00

abstract：:The mechanism of DNA degradation and its clinical applications were examined. When purified lambda phage and extracted liver DNA were fixed in phosphate buffered formaldehyde, the DNA did not degrade, but there was incomplete digestion with endonuclease. Rat liver tissues were fixed under various conditions and DNA ex...

journal_title：Journal of clinical pathology

authors： Tokuda Y,Nakamura T,Satonaka K,Maeda S,Doi K,Baba S,Sugiyama T

更新日期：1990-09-01 00:00:00

abstract：:Factor VIII-containing materials were administered to four severely affected haemophiliacs twice weekly in doses calculated to raise the factor VIII level to either 15% or 30% of average normal. The pooled results from those patients with statistically similar baseline bleeding frequencies showed a significant reducti...

journal_title：Journal of clinical pathology

authors： Aronstam A,Kirk PJ,McHardy J,Culver-James JW,McLellan DS,Turk P,Rainsford SG,Slattery M

更新日期：1977-01-01 00:00:00