Dose response relationships and interference of simultaneous skin tests in delayed hypersensitivity.

abstract：AIMS:To compare prognostic information obtained by image analysis cytometry of paraffin wax embedded soft tissue sarcomas with conventional assessment. METHODS:A CAS 200 image analyser was used to determine DNA content of Feulgen stained cytology preparations and tissue sections and to quantify immunostaining by Ki67 ...

journal_title：Journal of clinical pathology

authors： Michie BA,Black C,Reid RP,Barrett A,Hamblen DL

更新日期：1994-05-01 00:00:00

abstract：AIMS:To determine how epithelial and stromal thymidine phosphorylase expression affects angiogenesis, rapid tumour growth, and decreased apoptotic activity in cervical cancer at varying stages of progression. METHODS:Epithelial and stromal thymidine phosphorylase expression, the microvessel count (reflected by factor ...

journal_title：Journal of clinical pathology

authors： Fujiwaki R,Hata K,Iida K,Maede Y,Koike M,Miyazaki K

更新日期：1999-08-01 00:00:00

abstract：:Increasingly in the field of medicine, new therapeutic modalities, both surgical and non-surgical, are being introduced. Some of these may significantly alter the pathological appearance of normal and neoplastic tissue and result in problems for the pathologist. In this review, iatrogenic pathology within the female g...

journal_title：Journal of clinical pathology

authors： Clarke B,McCluggage WG

更新日期：2009-02-01 00:00:00

abstract：:In four persons of one family the existence of an enzymatic defect, presumably consisting of a deficiency of glutaminase in the cells of the renal tubules, is postulated, and is implied by a reduced elimination of ammonia in the urine, by a relatively low urinary pH, and by its increased titratable acidity. The most c...

journal_title：Journal of clinical pathology

authors： KRAWCZYNSKI J,SAGAN Z,WALAJTYS E,ILOWIECKA K

更新日期：1965-03-01 00:00:00

abstract：:The routine estimation of large numbers of serum folic acid and vitamin B(12) levels using the Baird and Tatlock(1) Analmatic clinical system is described and the method evaluated.Precision, accuracy, and carryover are shown to be at acceptable levels, and the advantages and disadvantages of the use of the system are ...

journal_title：Journal of clinical pathology

authors： Colvin G,Gibson GL,Neill DW

更新日期：1971-02-01 00:00:00

abstract：:In situ hybridisation, immunohistochemistry, and morphological analysis for the detection of cytomegalovirus (CMV) were compared in routinely processed tissue sections from a patient with acquired immune deficiency syndrome (AIDS) and widespread CMV infection. Both in situ hybridisation and immunohistochemistry with t...

journal_title：Journal of clinical pathology

authors： Niedobitek G,Finn T,Herbst H,Gerdes J,Grillner L,Landqvist M,Wirgart BZ,Stein H

更新日期：1988-09-01 00:00:00

abstract：AIMS:As part of the UK antimicrobial resistance strategy and action plan, the Public Health Laboratory Service (PHLS) is required to collect antibiotic susceptibility data so that resistance trends and patterns can be monitored. Most laboratories report urine Gram negative isolates, as "coliforms" according to morpholo...

journal_title：Journal of clinical pathology

authors： Fallon D,Andrews N,Frodsham D,Gee B,Howe S,Iliffe A,Nye KJ,Warren RE

更新日期：2002-07-01 00:00:00

abstract：:The apparent volumes of distribution of Evans blue and (59)Fe-dextran were determined in 18 studies.(59)Fe-dextran volume was 5% lower than Evans blue volume, a highly significant difference. The rate of loss of (59)Fe dextran from the circulation was significantly less than that of Evans blue. ...

journal_title：Journal of clinical pathology

authors： Wilson RJ,Mills IH

更新日期：1970-05-01 00:00:00

abstract：:The case records and pathology of all children with kidney tumours treated in the West Midlands Health Authority Region (WMHAR) from 1957 to 1986 were reviewed. The histology was reviewed by a panel of three paediatric pathologists. Thirteen (6%) out of 211 cases were considered to have congenital mesoblastic nephroma...

journal_title：Journal of clinical pathology

authors： Barrantes JC,Toyn C,Muir KR,Parkes SE,Raafat F,Cameron AH,Marsden HB,Mann JR

更新日期：1991-04-01 00:00:00

abstract：AIMS:N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been shown to be useful for ruling out heart failure in primary care. In this study, we examined the accuracy of the Cobas h232 point-of-care (POC) instrument in primary care compared with an in-hospital measurement. Furthermore, we investigated the user-fr...

journal_title：Journal of clinical pathology

authors： Hex C,Smeets M,Penders J,Van Hoof V,Verbakel J,Buntinx F,Vaes B

更新日期：2018-06-01 00:00:00

abstract：:During a two-year period of observation Bacteroides species were isolated from specimens of pus and vaginal swabs from 115 patients in this hospital. Thirty-five representative strains proved on examination to be Bacteroides fragilis. Minimal inhibitory and minimal bactericidal concentrations of six antibiotics for th...

journal_title：Journal of clinical pathology

authors： Ingham HR,Selkon JB,Codd AA,Hale JH

更新日期：1968-07-01 00:00:00

abstract：AIMS:To identify the number and geographical distribution of post mortem examinations performed on HIV infected cadavers; to identify the areas that perform post mortem examinations so that, by invitation and discussion, a national post mortem network could be initiated. METHODS:A nationwide survey of Royal College of...

journal_title：Journal of clinical pathology

authors： Davies J,Everall IP,Lantos PL

更新日期：1993-12-01 00:00:00

abstract：:Common acute lymphoblastic leukaemia antigen (CALLA) was first characterised in lymphoid leukaemic cells. The antigen is present in different stages of lymphoid cell differentiation as well as in subsets of myeloid cells, and further studies have also shown its presence in non-lymphoid tissues. The recent cloning and ...

journal_title：Journal of clinical pathology

authors： Loke SL,Leung CY,Chiu KY,Yau WL,Cheung KN,Ma L

更新日期：1990-08-01 00:00:00

abstract：:Severe osteomalacia (confirmed by the examination of thin undecalcified bone biopsy sections) associated with hypophosphataemia developed in a 60 year old woman. A skeletal x-ray survey showed a lytic lesion in the right proximal femur, and this was curetted, showing a vascular tumour. The patient's symptoms improved ...

journal_title：Journal of clinical pathology

authors： McClure J,Smith PS

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Thyrotropin-secreting adenomas (TSH-As) are rare and, according to the World Health Organization criteria (WHO 2004), a significant proportion of them present features of atypical adenomas at the time of diagnosis. AIMS:To determine the frequency of "atypical adenomas" and the significance of this definitio...

journal_title：Journal of clinical pathology

authors： Marucci G,Faustini-Fustini M,Righi A,Pasquini E,Frank G,Agati R,Foschini MP

更新日期：2009-05-01 00:00:00

abstract：:This review focuses on the pathological features of dysplasia in Barrett's oesophagus. Two categorisation schemes are used for grading dysplasia in the gastrointestinal tract, including Barrett's oesophagus. The inflammatory bowel disease dysplasia morphology study group system is the one most commonly used in the USA...

journal_title：Journal of clinical pathology

authors： Odze RD

更新日期：2006-10-01 00:00:00

abstract：:An antibody was raised against a protein isolated from the cytoplasm of mesothelioma cells. It was subsequently used in an immunoperoxidase procedure on formalin fixed, paraffin embedded tissue sections. A representative sample of benign and malignant tumours from all the systems of the human body was examined. All th...

journal_title：Journal of clinical pathology

authors： Donna A,Betta PG,Bellingeri D,Marchesini A

更新日期：1986-09-01 00:00:00

abstract：AIMS:PCR amplicon-based next-generation sequencing (NGS) panels are increasingly used for clinical diagnostic assays. Amplification bias is a well-known limitation of PCR amplicon-based approaches. We sought to characterise lower-performance amplicons in an off-the-shelf NGS panel (TruSight Myeloid Sequencing Panel) fo...

journal_title：Journal of clinical pathology

authors： Yan B,Hu Y,Ng C,Ban KH,Tan TW,Huan PT,Lee PL,Chiu L,Seah E,Ng CH,Koay ES,Chng WJ

更新日期：2016-09-01 00:00:00

abstract：:The indirect immunofluorescence technique was used to study the expression of the blood group A and H antigens in fresh-frozen and formalin-fixed paraffin-embedded sections of the bladder mucosa of 21 patients with non-neoplastic diseases of the bladder. Reliable assessment of these antigens could only be made using c...

journal_title：Journal of clinical pathology

authors： Thorpe SJ,Abel P,Slavin G,Feizi T

更新日期：1983-08-01 00:00:00

abstract：AIMS:Iron overload is a major factor contributing to the overall pathology of thalassaemia, which is primarily mediated by ineffective erythropoiesis and shorter mature red blood cell (RBC) survival. Iron accumulation in RBCs generates reactive oxygen species (ROS) that cause cellular damage such as lipid peroxidation ...

journal_title：Journal of clinical pathology

authors： Chaichompoo P,Qillah A,Sirankapracha P,Kaewchuchuen J,Rimthong P,Paiboonsukwong K,Fucharoen S,Svasti S,Worawichawong S

更新日期：2019-08-01 00:00:00

abstract：:A chemical method for the sterilization of pancreatin and trypsin is given. Evidence is presented to show that this treatment does not diminish the specific activity of the enzymes and has some advantages in microbiological techniques. ...

journal_title：Journal of clinical pathology

authors： Stokes KJ

更新日期：1971-10-01 00:00:00

abstract：:A total of 104 clinical isolates of Pr. mirabilis from three hospitals were screened for their sensitivity to chlorhexidine. The minimum inhibitory concentrations of the antiseptic for these strains ranged from 10 to 800 mug/ml. Two strains sensitive to 20 mug of chlorhexidine/ml were adapted to resistance by growth i...

journal_title：Journal of clinical pathology

authors： Stickler DJ

更新日期：1974-04-01 00:00:00

abstract：:Fifty-three breast carcinomas were examined by an indirect immunoperoxidase technique for the presence of the alpha-subunit of human chorionic gonadotrophin. Positive staining occurred in 12 (22.6%). There was no correlation between alpha-subunit production and specific histological features, but production was relate...

journal_title：Journal of clinical pathology

authors： Walker RA

更新日期：1978-03-01 00:00:00

abstract：:Protein HC and protein HC-IgA complex were measured in 18 different types of fluid sample from healthy subjects and patients with different illnesses to determine if the concentrations of protein HC and protein HC-IgA complexes could be used to monitor certain diseases, when measured separately. The normal values for ...

journal_title：Journal of clinical pathology

authors： Fernández-Luna JL,Leyva-Cobián F,Méndez E

更新日期：1988-11-01 00:00:00

abstract：AIMS:To develop a specific radioimmunoassay for the routine determination of serum vitamin B12. METHODS:Antisera were raised in rabbits by immunisation with the monocarboxylic acid derivative of cyanocobalamin coupled to human serum albumin. Antibody titres and affinities were determined and the antiserum giving the h...

journal_title：Journal of clinical pathology

authors： O'Sullivan JJ,Leeming RJ,Lynch SS,Pollock A

更新日期：1992-04-01 00:00:00

abstract：AIMS:To develop a readily applicable polymerase chain reaction (PCR) based technique which would permit the identification of Mycobacterium tuberculosis complex isolates from Bactec phials at an earlier stage than currently available methods. METHODS:Mycobacterial cells cultured in Bactec 12B medium were harvested by ...

journal_title：Journal of clinical pathology

authors： Cormican MG,Barry T,Gannon F,Flynn J

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:Few studies have modelled the economics of thyroid FNA. METHODS:A simple spreadsheet economic model for delivery of thyroid fine needle aspiration (FNA) cytology is described using the UK Royal College of Pathologists' Classification for thyroid FNA which is based on The Bethesda System for Reporting Thyroid...

journal_title：Journal of clinical pathology

authors： Poller DN,Kandaswamy P

更新日期：2013-07-01 00:00:00

abstract：:Experiments are described with glass fibre filter paper and complete glass filters as fitted to high pre-vacuum autoclaves to determine whether organisms can grow or penetrate through the filters. A filter consisting of four layers of glass fibre paper fitted inside a sterilizer chamber for a year and used for 96 ster...

journal_title：Journal of clinical pathology

authors： Fallon RJ

更新日期：1963-05-01 00:00:00

abstract：BACKGROUND:Fungal infection is increasingly recognised as an important cause of morbidity and mortality, especially in immunocompromised patients. Little information exists on laboratory services available and the methods used by general microbiology laboratories to diagnose these important infections. AIM:To investig...

journal_title：Journal of clinical pathology

authors： Hassan IA,Critten P,Isalska B,Denning DW

更新日期：2006-07-01 00:00:00

abstract：AIMS:To assess the consistency and reproducibility of assessment of c-erbB-2 immunostaining, and to examine some of the problems relating to inter- and intraobserver variability in the documentation of positive staining; to profile the spectrum of cytoplasmic and membranous staining in a wide range of tumour types. ME...

journal_title：Journal of clinical pathology

authors： Kay EW,Walsh CJ,Cassidy M,Curran B,Leader M

更新日期：1994-09-01 00:00:00