Post mortem examinations of HIV infected patients: a nationwide survey.

abstract：:We present the pathological findings in a case of acquired immunodeficiency syndrome (AIDS) in a patient with no known risk factor. Postmortem examination showed klebsiella lung abscess, generalised cytomegalovirus infection, cerebral toxoplasmosis, and a primary cerebral lymphoma. An additional feature was the presen...

journal_title：Journal of clinical pathology

authors： Burt AD,Scott G,Shiach CR,Isles CG

更新日期：1984-04-01 00:00:00

abstract：:Chronic myelomonocytic leukaemia (CMML) is a myelodysplastic syndrome with a diverse clinical spectrum. A case of a 60 year old man with CMML who developed cardiac tamponade is reported. Cytological examination of the pericardial effusion fluid showed extramedullary haemopoiesis. Serous effusions are well recognised i...

journal_title：Journal of clinical pathology

authors： Bradford CR,Smith SR,Wallis JP

更新日期：1993-07-01 00:00:00

abstract：AIM:To assess the topographical relation between gastric glands, using the minimum spanning tree (MST), to derive both a model of neighbourhood and quantitative representation of the tissue's architecture, to assess the characteristic features of gastric atrophy, and to assess the grades of gastric atrophy. METHODS:Ha...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,al Mardini H,Record CO

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Oncogenicity of human papillomavirus (HPV) DNA in premalignant and malignant uterine cervical diseases is mainly induced by E6/E7 open reading frame (ORF). The presence of an oncogenic HPV DNA may be a diagnostic marker for the detection of cytologically negative smears. AIMS:To evaluate an original polymer...

journal_title：Journal of clinical pathology

authors： Clavel C,Rihet S,Masure M,Chypre C,Boulanger JC,Quereux C,Birembaut P

更新日期：1998-01-01 00:00:00

abstract：:Care in the preparation and preservation of reagents, together with certain modifications in apparatus and technique, have eliminated the difficulties from plasma ammonia analysis. Ammonia contamination from the laboratory atmosphere has not proved an especial hazard, and no major setback has been encountered in the a...

journal_title：Journal of clinical pathology

authors： Fenton JC,Williams AH

更新日期：1968-01-01 00:00:00

abstract：:Carcinoma-associated fibroblast (CAF) as prominent cell type of the tumour microenvironment has complex interaction with both the cancer cells and other non-neoplastic surrounding cells. The CAF-derived regulators and extracellular matrix proteins can support cancer progression by providing a protective microenvironme...

journal_title：Journal of clinical pathology

authors： Valcz G,Sipos F,Tulassay Z,Molnar B,Yagi Y

更新日期：2014-12-01 00:00:00

abstract：AIMS:To develop a quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) for severe acute respiratory syndrome coronavirus (SARS-CoV) detection and explore the potential of using glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA as an internal control to exclude false negative results. METHODS:SAR...

journal_title：Journal of clinical pathology

authors： Wong SC,Chan JK,Lee KC,Lo ES,Tsang DN

更新日期：2005-03-01 00:00:00

abstract：AIM:To examine a model for the evaluation of appropriateness of testing in an emergency biochemistry laboratory. METHODS:A model was devised in which incoming emergency test requests were categorised as appropriate or inappropriate. Explicit criteria were used to define eight minor categories, which were chosen to ref...

journal_title：Journal of clinical pathology

authors： Smellie WS,Murphy MJ,Galloway PJ,Hinnie J,McIlroy J,Dryburgh FJ

更新日期：1995-12-01 00:00:00

abstract：:A manual system of microbiology reporting with a National Cash Register (NCR) form with printed names of bacteria and antiboitics required less time to compose reports than a previous manual system that involved rubber stamps and handwriting on plain report sheets. The NCR report cost 10-28 pence and, compared with a ...

journal_title：Journal of clinical pathology

authors： Goodwin CS

更新日期：1976-06-01 00:00:00

abstract：:A 45-year-old female patient underwent right hemihepatectomy for metastatic rectal adenocarcinoma. Preoperative imaging demonstrated an area of focal nodular hyperplasia (FNH) in segment VIII and metastatic carcinoma in segment VI of the liver. Gross and microscopic examination of the former lesion showed features typ...

journal_title：Journal of clinical pathology

authors： Nisar PJ,Zaitoun AM,Damera A,Hodi Z,Tierney GM,Beckingham IJ

更新日期：2002-12-01 00:00:00

abstract：:This article reviews recent information concerning the origin of osteoclasts and the local and systemic regulation of their activity. It appears that much of the environmental responsiveness of osteoclasts is mediated by cells of the osteoblastic lineage, which exert a major influence on the localisation, induction, s...

journal_title：Journal of clinical pathology

authors： Chambers TJ

更新日期：1985-03-01 00:00:00

abstract：:In a twenty-year period 19 appendicectomy specimens were diagnosed as primary Crohn's disease. This represents 4.9% of the total number of both resection specimens and mucosal biopsies diagnosed as Crohn's disease during that time. This is a review of the main histopathological features found in these appendices and t...

journal_title：Journal of clinical pathology

authors： Allen DC,Biggart JD

更新日期：1983-06-01 00:00:00

abstract：:Distinctly increased levels of antibodies to measles virus envelope antigens haemolysin and haemagglutinin were found in the sera of patients with chronic active hepatitis compared with a normal control group, using immunofluorescence and functional tests. Similarly, a higher incidence of smooth muscle antibody of bot...

journal_title：Journal of clinical pathology

authors： Shirodaria PV,McMillan SA,Callender ME,Haire M,Fleming E,Merrett JD,Fulton TT

更新日期：1985-11-01 00:00:00

abstract：:Extracts of the seeds of Vicia cretica (NO Leguminosae) strongly agglutinate T- Th- but not Tk- or other polyagglutinable red cells. The V. cretica lectin is therefore a very useful laboratory reagent in the elucidation of erythrocyte polyagglutination due to T-like erythrocyte cryptantigens. ...

journal_title：Journal of clinical pathology

authors： Bird GW,Wingham J

更新日期：1981-01-01 00:00:00

abstract：AIMS:To perform a clinicopathological analysis of a series of primary cutaneous Ewing sarcomas/primitive neuroectodermal tumours (ES/PNET) to highlight the pathological features, discuss the differential diagnosis, emphasise the role of molecular testing (particularly fluorescence in situ hybridisation, FISH) in diagno...

journal_title：Journal of clinical pathology

authors： Shingde MV,Buckland M,Busam KJ,McCarthy SW,Wilmott J,Thompson JF,Scolyer RA

更新日期：2009-10-01 00:00:00

abstract：:An immunological method for detecting fibrin degradation products by tanned cells agglutination has been standardized. The effects of different variables, such as cell concentration, pH, and length of incubation, and the specificity of the reaction, are described. The method is compared with other immunological techni...

journal_title：Journal of clinical pathology

authors： Das PC

更新日期：1970-05-01 00:00:00

abstract：:Gastroblastoma is a rare gastric epitheliomesenchymal biphasic tumour composed of spindle and epithelial cells, reported by Miettinen et al in a series of three cases in 2009. All those cases arose in stomachs of young adults. Neither the epithelial nor the mesenchymal component displayed sufficient atypia to diagnose...

journal_title：Journal of clinical pathology

authors： Shin DH,Lee JH,Kang HJ,Choi KU,Kim JY,Park DY,Lee CH,Sol MY,Park JH,Kim HY,Montgomery E

更新日期：2010-03-01 00:00:00

abstract：AIMS:Congenital neutropenia (CN) is a rare inherited disease that results in recurrent, life-threatening bacterial infections due to a deficiency of mature neutrophils. They are usually caused by heterozygous ELANE mutations although mutations in other genes like HAX-1, G6PC3 and GFI1 have also been reported. Identifyi...

journal_title：Journal of clinical pathology

authors： Arunachalam AK,Suresh H,Edison ES,Korula A,Aboobacker FN,George B,Shaji RV,Mathews V,Balasubramanian P

更新日期：2020-06-01 00:00:00

abstract：AIMS:To assess the distribution of gamma delta T-cells in the human bronchial tree; and to compare quantitatively the differences between gamma delta T-cell numbers in different parts of the airway wall in smokers and non-smokers. METHODS:Full thickness bronchial wall sections were taken from 10 whole lung specimens f...

journal_title：Journal of clinical pathology

authors： Richmond I,Pritchard GE,Ashcroft T,Corris PA,Walters EH

更新日期：1993-10-01 00:00:00

abstract：AIMS:Most benign breast fibroepithelial lesions (FEL) in adults harbour recurrent somatic MED12 exon 2 mutations and rare TERT promoter hotspot mutations. We sought to determine the frequency of MED12 exon 2 and TERT promoter hotspot mutations in fibroadenomas (FA) and benign phyllodes tumours (BePT) in adolescents and...

journal_title：Journal of clinical pathology

authors： Pareja F,Da Cruz Paula A,Murray MP,Hoang T,Gularte-Mérida R,Brown D,da Silva EM,Sebastiao APM,Giri DD,Weigelt B,Reis-Filho JS,Brogi E

更新日期：2019-03-01 00:00:00

abstract：AIM:The evaluation of allelic losses at the FHIT and the BRCA1 genes and at three other loci at the 17q region in a series of 34 sporadic breast cancer cases from Southern Brazil. METHODS:The samples were evaluated for loss of heterozygosity (LOH) at the FHIT and the BRCA1 genes and at three other microsatellite marke...

journal_title：Journal of clinical pathology

authors： Santos SC,Cavalli LR,Cavalli IJ,Lima RS,Haddad BR,Ribeiro EM

更新日期：2004-04-01 00:00:00

abstract：AIMS:To characterise further the proliferative compartment of the normal cervix and to document its alteration, if any, in the various grades of cervical intraepithelial neoplasia (CIN), particularly changes to the basal epithelial layer; to hypothesise as to the diagnostic and biological significance of any observed d...

journal_title：Journal of clinical pathology

authors： Payne S,Kernohan NM,Walker F

更新日期：1996-08-01 00:00:00

abstract：AIMS:To test whether a hypoacidic environment may potentially "stress" Helicobacter pylori DNA, encouraging the emergence of strain variation. METHODS:This hypothesis was tested by inducing prolonged hypoacidity with omeprazole, a potent antisecretory drug. The genomic DNA of H pylori was studied by electrophoretic se...

journal_title：Journal of clinical pathology

authors： Fraser AG,Bickley J,Owen RJ,Pounder RE

更新日期：1992-12-01 00:00:00

abstract：AIMS:Pim-1 is a serine/threonine kinase that has been shown to play an integral role in the development of a number of human cancers, such as haematolymphoid malignancies. Recently, evidence has shown Pim-1 to be important in prostatic carcinogenesis. In order to further our understanding of its role in prostate cancer...

journal_title：Journal of clinical pathology

authors： Cibull TL,Jones TD,Li L,Eble JN,Ann Baldridge L,Malott SR,Luo Y,Cheng L

更新日期：2006-03-01 00:00:00

abstract：:The morphological classification and diagnosis of bladder neoplasms is summarised, with specific focus on histological typing, grading and staging. Four diagnostic categories are described on the basis of the pattern of growth of the urothelial lesions and tumours (flat, exophytic or papillary, endophytic, and invasiv...

journal_title：Journal of clinical pathology

authors： Montironi R,Mazzucchelli R,Scarpelli M,Lopez-Beltran A,Cheng L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Intraoperative frozen section (FS) examination in thoracic surgery is a reliable method for diagnosis and staging of pulmonary lesions and provides a valuable guide in directing the extent of the ongoing surgical procedure. However, the contribution of touch preparation cytology (TPC) to FS diagnosis remains...

journal_title：Journal of clinical pathology

authors： Rakha EA,Haider A,Patil S,Fourtan H,Chaudry Z,Soomro IN

更新日期：2010-08-01 00:00:00

abstract：AIMS:Common variable immunodeficiency (CVID) is the most common serious primary immunodeficiency. This paper describes the immunological consequences of human immunodeficiency virus (HIV) infection in a patient with familial CVID subsequently treated with highly active antiretroviral therapy (HAART). METHODS:Serial me...

journal_title：Journal of clinical pathology

authors： Jolles S,Tyrer M,Johnson M,Webster D

更新日期：2001-09-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) is a zoonotic viral infection originating from Wuhan, China in December 2019. The World Health Organization has classified this pandemic as a global health emergency due to its virulent nature of transmission, which may lead to acute respiratory distress syndrome. Singapore's he...

journal_title：Journal of clinical pathology

authors： Tan SS,Yan B,Saw S,Lee CK,Chong AT,Jureen R,Sethi S

更新日期：2020-03-20 00:00:00

abstract：:Although the morphology of the pathognomonic Reed-Sternberg cells of Hodgkin lymphoma (HL) was described over a century ago, it was not until recently that their origin from B lymphocytes was recognised. The demonstration that a proportion of cases of HL harbour the Epstein-Barr virus (EBV) and that its genome is mono...

journal_title：Journal of clinical pathology

authors： Kapatai G,Murray P

更新日期：2007-12-01 00:00:00

abstract：:Human sperm heads were detected and tracked using semiautomatic image analysis. Measurements of size and shape on two specimens from each of 26 men showed that the major component of variability both within and between subjects was the number of small elongated sperm heads. Variability of the computed features between...

journal_title：Journal of clinical pathology

authors： Jagoe JR,Washbrook NP,Hudson EA

更新日期：1986-12-01 00:00:00