Extensive perinephric abscess complicated by herpes simplex virus 1 reactivation.

Abstract:

:A 43-year-old man, admitted with a swollen right thigh, was diagnosed with a deep vein thrombosis. On day 6 he became septic. A CT scan demonstrated a right-sided hydronephrosis and a large retroperitoneal collection. Blood cultures and perinephric pus grew Escherichia coli resistant to amoxicillin only. On day 12 a vesicular rash appeared on the neck and herpes simplex virus 1 (HSV-1) grew on culture. On day 15 an upper leg collection was seen on CT scan. Thigh tissue specimens grew extended-spectrum beta-lactamase (ESBL) producing E coli and HSV-1 was also detected by polymerase chain reaction in the tissue. On day 18 the patient died. This case illustrates an unusual presentation and complication of a perinephric abscess. In critically ill patients herpes simplex reactivation and emergence of multiresistant organisms may occur resulting in treatment failure.

journal_name

J Clin Pathol

authors

Alleyne SA,Bukhari SS,Fraser M,Spiers P

doi

10.1136/jcp.2009.071787

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

365-6

issue

4

eissn

0021-9746

issn

1472-4146

pii

63/4/365

journal_volume

63

pub_type

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