Corticosteroids as adjunctive treatment in Austrian's syndrome (pneumococcal endocarditis, meningitis, and pneumonia): report of two cases and review of the literature.

Abstract:

:This report describes two cases of Osler's triad of pneumonia, meningitis, and endocarditis, as a result of Streptococcus pneumoniae infection, also called Austrian's syndrome. In the first patient, a 51 year old non-alcoholic man, the aortic valve was affected and needed to be replaced in an emergency operation. The mitral valve was affected in a 70 year old woman without underlying disease, who only benefited from medical treatment. Both patients received corticosteroids, either dexamethasone followed by low doses of hydrocortisone and fludrocortisone, or only hydrocortisone and fludrocortisone, at the onset of the illness, and their outcome was favourable. These case reports focus on the presentation, prognosis, and therapeutic options for this severe syndrome.

journal_name

J Clin Pathol

authors

du Cheyron D,Lesage A,Le Page O,Flais F,Leclercq R,Charbonneau P

doi

10.1136/jcp.56.11.879

keywords:

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

879-81

issue

11

eissn

0021-9746

issn

1472-4146

journal_volume

56

pub_type

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