A proposal for a standardized system of reporting human lymph node morphology in relation to immunological function.

abstract：:Forty six lymph nodes were examined with the indirect immunoperoxidase technique for the distribution of fibronectin and laminin. Fibronectin was present in the framework of the tissue and the basal lamina of blood vessels, giving a clear outline of nodal architecture. Intracellular fibronectin was observed in cases o...

journal_title：Journal of clinical pathology

authors： Reilly JT,Nash JR,Mackie MJ,McVerry BA

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Hsulf-1 is a newly identified enzyme with arylsulphatase activity that can regulate the sulphation state of cell-surface heparan sulphate proteoglycans (HSPGs). In vitro overexpression of this enzyme in pancreatic cancer cells decreases responsiveness to fibroblastic growth factor-2, as Hsulf-1 is up regulat...

journal_title：Journal of clinical pathology

authors： Abiatari I,Kleeff J,Li J,Felix K,Büchler MW,Friess H

更新日期：2006-10-01 00:00:00

abstract：:Experiments were performed to evaluate five commercial kit assays used for the detection of antibodies to dsDNA. The kits were compared using a performance index score as recommended by the guidelines of the European Committee for Clinical Laboratory Standards. The highest performance score was obtained using the radi...

journal_title：Journal of clinical pathology

authors： McMillan SA,Fay AC

更新日期：1988-11-01 00:00:00

abstract：:Cryostat sections from 160 rectal suction biopsies were stained for cholinesterases by the method of Karnovsky and Roots (1964) in an attempt to facilitate the diagnosis of Hirschsprung's disease. The method proved at least as reliable as experienced assessment of paraffin haematoxylin-eosin sections, and appeared to ...

journal_title：Journal of clinical pathology

authors： Trigg PH,Belin R,Haberkorn S,Long WJ,Nixon HH,Plaschkes J,Spitz L,Willital GH

更新日期：1974-03-01 00:00:00

abstract：AIMS:To evaluate aspects of the current practice of sentinel lymph node (SLN) pathology in breast cancer via a questionnaire based survey, to recognise major issues that the European guidelines for mammography screening should address in the next revision. METHODS:A questionnaire was circulated by mail or electronical...

journal_title：Journal of clinical pathology

authors： Cserni G,Amendoeira I,Apostolikas N,Bellocq JP,Bianchi S,Boecker W,Borisch B,Connolly CE,Decker T,Dervan P,Drijkoningen M,Ellis IO,Elston CW,Eusebi V,Faverly D,Heikkila P,Holland R,Kerner H,Kulka J,Jacquemier J,La

更新日期：2004-07-01 00:00:00

abstract：AIMS:To develop a rapid, sensitive, and specific non-isotopic in situ hybridisation (NISH) procedure for the detection of Epstein-Barr virus in formalin fixed, paraffin wax embedded tissues. METHODS:Two low molecular weight RNAs, designated EBER-1 and EBER-2 (Epstein-Barr encoded RNA), were used: cells latently infect...

journal_title：Journal of clinical pathology

authors： Khan G,Coates PJ,Kangro HO,Slavin G

更新日期：1992-07-01 00:00:00

abstract：AIMS/BACKGROUND:Telomerase, an enzyme associated with cellular immortality, is expressed by most malignant tumours, but is inactive in normal somatic cells except for male germ cells and proliferating stem cells. Thus, the measurement of telomerase activity in tissue samples may provide useful diagnostic and prognostic...

journal_title：Journal of clinical pathology

authors： Yashima K,Piatyszek MA,Saboorian HM,Virmani AK,Brown D,Shay JW,Gazdar AF

更新日期：1997-02-01 00:00:00

abstract：:Two examples of intraplacental choriocarcinoma are described. Both were small and had arisen in otherwise normal third trimester placentas. The covering mantle of many of the villi adjacent to the choriocarcinomas was formed, either focally or wholly, of neoplastic trophoblastic tissue: it is only at this stage of the...

journal_title：Journal of clinical pathology

authors： Fox H,Laurini RN

更新日期：1988-10-01 00:00:00

abstract：:Statistical tables including 50 and 95 percentile ranges are presented of the combined kidney weights compared with body weight, crown-rump length, and gestation age of foetuses and newborn children, and also a table of kidney weights related to post-natal age. The importance of relating kidney weight to more than one...

journal_title：Journal of clinical pathology

authors： EMERY JL,MITHAL A

更新日期：1960-11-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the risk factors for proximal resection margin involvement and its impact on survival outcome in patients with proximal gastric cancer. METHODS:A total of 488 patients who underwent potentially curative resection for proximal gastric cancer were retrospectively reviewed. Clini...

journal_title：Journal of clinical pathology

authors： Zhao B,Lu H,Bao S,Luo R,Mei D,Xu H,Huang B

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:RCAS1 (receptor binding cancer antigen expressed on SiSo cells) is a tumour associated antigen. It is involved in immune evasion by tumour cells, by binding to receptors on cells involved in the immune response, such as T cells and natural killer cells, and inducing apoptosis. High expression of RCAS1 has be...

journal_title：Journal of clinical pathology

authors： Leelawat K,Watanabe T,Nakajima M,Tujinda S,Suthipintawong C,Leardkamolkarn V

更新日期：2003-10-01 00:00:00

abstract：:Xanthine oxidase (XO) activity was found to be negligible in sterile human urines (less than 480 units, as presently defined, per litre). Significant XO activity was found in all urines containing more than 10(5) bacteria/ml, except for urines infected with Staphylococcus aureus, in which XO activity ranged from 347 t...

journal_title：Journal of clinical pathology

authors： Giler S,Henig EF,Urca I,Sperling O,de Vries A

更新日期：1978-05-01 00:00:00

abstract：:During a 12-month period, 40 146 blood donors were tested for the presence of high titre antitetanus antibodies. An attempt has been made to define the most suitable donors, those with antitetanus antibody titres of 4 IU/ml or above, by virtue of titre, sex, location, and length of time since most recent immunisation...

journal_title：Journal of clinical pathology

authors： Wiseman IC,Gascoigne ME

更新日期：1977-02-01 00:00:00

abstract：AIMS:Inflammatory bowel disease (IBD)-associated precancerous lesions may be adenomatous or non-adenomatous with various histomorphologies. We aim to validate the newly proposed classification, to explore the neoplastic nature of the non-adenomatous lesions and to elucidate the molecular mechanisms underlying the diffe...

journal_title：Journal of clinical pathology

authors： Gui X,Köbel M,Ferraz JG,Iacucci M,Ghosh S,Liu S,Ou Y,Perizzolo M,Winkfein RJ,Rambau P,Demetrick DJ

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:For breast and prostate cancer, a gene expression signature of the tumour is associated with the development of distant metastases. Regarding head and neck squamous cell carcinoma (HNSCC), the only known risk factor is the presence of > or =3 tumour-positive lymph nodes. AIM:To evaluate whether a HNSCC gene...

journal_title：Journal of clinical pathology

authors： Braakhuis BJ,Senft A,de Bree R,de Vries J,Ylstra B,Cloos J,Kuik DJ,Leemans CR,Brakenhoff RH

更新日期：2006-12-01 00:00:00

abstract：:Rates of urinary excretion concomitant with the molecular size distribution of filtered polymer fragments were determined in five normovolaemic men dosed with 30 g/m2 BSA of a species of HES (HES 350/0.60) possessing a M-W of 350 000 combined with an MS of 0.60. Approximately 13% of the total injected dose of HES 350/...

journal_title：Journal of clinical pathology

authors： Mishler JM,Ricketts CR,Parkhouse EJ

更新日期：1981-04-01 00:00:00

abstract：:A questionnaire was circulated to clinical biochemistry laboratories in the North West Thames region of the United Kingdom requesting information on extralaboratory equipment. Data on the types and numbers of instruments in use, their relationship with the laboratory, and quality assurance procedures were obtained. La...

journal_title：Journal of clinical pathology

authors： Burrin JM,Fyffe JA

更新日期：1988-09-01 00:00:00

abstract：:Specimens of muscle were obtained from non-suppurating lesions of nine patients with tropical myositis. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure. Perimysial cells were also degenerate. Sections from two out of nine patients revealed intracellular vesicles,...

journal_title：Journal of clinical pathology

authors： Taylor JF,Fluck D,Fluck D

更新日期：1976-12-01 00:00:00

abstract：:Numerous clinical pathology departments are deploying or planning to deploy digital pathology systems for all or part of their diagnostic output. Digital pathology is an evolving technology, and it is important that departments uphold or improve on current standards. Leeds Teaching Hospitals NHS Trust has been scannin...

journal_title：Journal of clinical pathology

authors： Williams BJ,Treanor D

更新日期：2020-07-01 00:00:00

abstract：AIMS:To develop a readily applicable polymerase chain reaction (PCR) based technique which would permit the identification of Mycobacterium tuberculosis complex isolates from Bactec phials at an earlier stage than currently available methods. METHODS:Mycobacterial cells cultured in Bactec 12B medium were harvested by ...

journal_title：Journal of clinical pathology

authors： Cormican MG,Barry T,Gannon F,Flynn J

更新日期：1992-07-01 00:00:00

abstract：AIMS:To investigate the morphological and histopathological associations between an individual pit seen on stereomicroscopy or magnifying colonoscopy and an individual crypt seen in histological sections; and to examine these associations in colorectal tumours. METHODS:Fourteen thousand and twenty three cases were exa...

journal_title：Journal of clinical pathology

authors： Kudo S,Hirota S,Nakajima T,Hosobe S,Kusaka H,Kobayashi T,Himori M,Yagyuu A

更新日期：1994-10-01 00:00:00

abstract：:This report describes two cases of Osler's triad of pneumonia, meningitis, and endocarditis, as a result of Streptococcus pneumoniae infection, also called Austrian's syndrome. In the first patient, a 51 year old non-alcoholic man, the aortic valve was affected and needed to be replaced in an emergency operation. The ...

journal_title：Journal of clinical pathology

authors： du Cheyron D,Lesage A,Le Page O,Flais F,Leclercq R,Charbonneau P

更新日期：2003-11-01 00:00:00

abstract：:Serum haptoglobin levels have been studied in patients with a number of haemolytic disorders. In general, serum haptoglobins were low in patients with increased haemolysis. Values were reduced irrespective of whether haemolysis occurred intravascularly or extravascularly. The reduction was related to the amount of hae...

journal_title：Journal of clinical pathology

authors： Owen JA,de Gruchy GC,Smith H

更新日期：1960-11-01 00:00:00

abstract：:A woman with peripheral vascular disease developed cytomegalovirus colitis following repair of abdominal aortic aneurysm. Cytomegalovirus colitis developing in an immunocompetent individual may be caused by a breach in the integrity of the mucosal lining of the colon from various causes and should alert the clinician ...

journal_title：Journal of clinical pathology

authors： al Mahdy H

更新日期：1998-06-01 00:00:00

abstract：:The mucin and gland content of 26 rectal biopsy specimens--five normal specimens, 10 from patients with ulcerative colitis, and 11 from patients with Crohn's disease--were measured using a Quantimet image analyser. There was significantly less mucin in the groups with ulcerative colitis compared with either those with...

journal_title：Journal of clinical pathology

authors： McCormick DA,Horton LW,Mee AS

更新日期：1990-02-01 00:00:00

abstract：AIMS:The Royal College of Pathologists recommend that a median of at least 12 lymph nodes should be harvested during pathological staging of colorectal cancer. It is not always easy to harvest the required number, especially in patients with rectal cancer receiving neoadjuvant therapy. Lymph node revealing solutions, f...

journal_title：Journal of clinical pathology

authors： Horne J,Carr NJ,Bateman AC,Kandala N 2nd,Adams J,Silva S,Ryder I

更新日期：2016-06-01 00:00:00

abstract：AIMS:To determine the suitability of primary gel separation tubes for the storage of frozen sera intended for serological testing. METHODS:Blood samples from 102 patients were collected into gel separation tubes. The sera from these samples were split between the primary gel separation tubes and conventional plastic s...

journal_title：Journal of clinical pathology

authors： Ellis V,Charlett A,Bendall R

更新日期：2004-01-01 00:00:00

abstract：:A 51 year old woman presented with rectal bleeding from a mass lying just above the dentate line. Multiple biopsies were taken before the diagnosis of a benign lymphoid polyp was made. This is a rare condition that more commonly presents in children and poses a diagnostic challenge. ...

journal_title：Journal of clinical pathology

authors： Lloyd J,Darzi A,Teare J,Goldin RD

更新日期：1997-12-01 00:00:00

abstract：:An elution technique is described which gives eluates at least as potent as previously described methods. Elution can be completed in only 15 minutes. The method, a modification of that of Vos and Kelsall, is simple to carry out and requires the minimum of equipment. Studies have shown that the coating antibody is alm...

journal_title：Journal of clinical pathology

authors： RUBIN H

更新日期：1963-01-01 00:00:00

abstract：:A miniaturised method for the identification of anaerobic bacteria is described which employs microtitre fermentation tests, a spot indole test and a nitrate reduction disc test. The results obtained are directly comparable with those produced by a standard conventional method in use at present. ...

journal_title：Journal of clinical pathology

authors： Levett PN

更新日期：1984-01-01 00:00:00