Intraplacental choriocarcinoma: a report of two cases.

abstract：:The clinical and pathological findings in 23 patients with ischaemic lesions of the alimentary tract (ischaemic enterocolitis) are described. These are compared with findings in 13 patients with occlusive thrombosis of the superior mesenteric artery. The pathological features distinguishing the two conditions are disc...

journal_title：Journal of clinical pathology

authors： McDonald GS,Hourihane DO

更新日期：1972-02-01 00:00:00

abstract：AIM:Heart failure (HF) affects millions of older individuals in both developed and low/middle-income countries. Serum galectin-3 levels have been shown to have prognostic value. However, its use as a diagnostic biomarker has not been explored. The aim was to establish a saliva galectin-3 reference range and to demonstr...

journal_title：Journal of clinical pathology

authors： Zhang X,Wan Y,Chata R,Brazzale A,Atherton JJ,Kostner K,Dimeski G,Punyadeera C

更新日期：2016-12-01 00:00:00

abstract：:A method for the simultaneous labelling of terminal deoxynucleotidyl transferase (TdT) and membrane antigens is described. TdT is visualised in the cell nucleus with the peroxidase-antiperoxidase (PAP) method, and the immunogold method is used in combination with monoclonal antibodies against membrane antigens. The mo...

journal_title：Journal of clinical pathology

authors： Tavares de Castro J,San Miguel JF,Soler J,Catovsky D

更新日期：1984-06-01 00:00:00

abstract：:A rapid and reproducible electrophoretic method for the separation and quantitation of haemoglobins on cellulose acetate is described. The accuracy of the method and its possible sources of error are discussed. The normal range for haemoglobin A(2) by this method is 1% to 3% of the total haemoglobin concentration. Blo...

journal_title：Journal of clinical pathology

authors： Marengo-Rowe AJ

更新日期：1965-11-01 00:00:00

abstract：:Cervical smears were reviewed from 62 women who developed squamous carcinoma of the cervix up to 18 years later. The findings indicate that the prevention of cervical cancer by screening depends very largely on the detection of severe dyskaryosis. In this series there was no evidence that mild dyskaryosis was a foreru...

journal_title：Journal of clinical pathology

authors： Robertson JH,Woodend B,Elliott H

更新日期：1994-03-01 00:00:00

abstract：:A labial biopsy technique is described and was used to study 40 patients with connective tissue disease and 60 postmortem subjects. More than one focus of lymphocytes per 4 sq mm of minor salivary tissue was found to be a consistent finding in patients with Sjögren's disease. The labial biopsy is shown to be a further...

journal_title：Journal of clinical pathology

authors： Chisholm DM,Mason DK

更新日期：1968-09-01 00:00:00

abstract：AIMS:To establish the number of histological levels necessary for the evaluation of breast needle core biopsy (NCB) specimens taken from areas of mammographic calcification in patients presenting via the UK National Health Service Breast Screening Programme. METHODS:Retrospective review of a series of breast NCB speci...

journal_title：Journal of clinical pathology

authors： Kumaraswamy V,Carder PJ

更新日期：2007-06-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:A middle aged man developed very high fever, status epilepticus, and terminal acute renal failure with myoglobinuria after surgery. A post mortem examination showed widespread muscle necrosis with hypercontraction bands. Muscle enzyme studies and electron microscopic examination disclosed central core disease, a condi...

journal_title：Journal of clinical pathology

authors： Prescott RJ,Roberts SP,Williams G

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVES:As the best characterised cancer/testis antigen family members, melanoma-associated antigens (MAGE) have been reported to be expressed in various malignant tumours. However, the expression pattern of MAGE-A family in lung adenocarcinoma (LAC) specimens and their prognostic and therapeutic significance for pa...

journal_title：Journal of clinical pathology

authors： Sang M,Gu L,Yin D,Liu F,Lian Y,Zhang X,Liu S,Huang W,Wu Y,Shan B

更新日期：2017-06-01 00:00:00

abstract：:To assess the pattern and severity of liver disease in patients who had undergone jejuno-ileal bypass for the treatment of morbid obesity, 23 patients were biopsied, all of whom had had intact bypasses for more than 10 years. These were examined by light and electron microscopy. Previous biopsy specimens from each pat...

journal_title：Journal of clinical pathology

authors： Boon AP,Thompson H,Baddeley RM

更新日期：1988-12-01 00:00:00

abstract：AIMS:Meticillin-resistant Staphylococcus aureus (MRSA) strains isolated in Tawam Hospital, a tertiary care hospital in the United Arab Emirates, were examined in order to understand the reasons for a doubling of its incidence between 2003 and 2008 while maintaining the same infection control measures. METHODS:All cons...

journal_title：Journal of clinical pathology

authors： Sonnevend Á,Blair I,Alkaabi M,Jumaa P,Al Haj M,Ghazawi A,Akawi N,Jouhar FS,Hamadeh MB,Pál T

更新日期：2012-02-01 00:00:00

abstract：:Urine specimens were collected from 26 normal subjects, 10 patients with proven primary hyperparathyroidism, and eight patients with hypercalcaemia due to other causes. After overnight urine concentration, an oral water load was given to induce a diuresis and provide urine specimens with a relatively wide range of cre...

journal_title：Journal of clinical pathology

authors： Wills MR

更新日期：1969-05-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor (EGFR) gene mutation at the kinase domain and EGFR gene amplification are reported to be predictors of the response to EGFR tyrosine kinase inhibitors in lung cancer cases. In malignant mesothelioma (MM), the role of EGFR is less clear. METHODS:Thirty-eight MM specimens were...

journal_title：Journal of clinical pathology

authors： Enomoto Y,Kasai T,Takeda M,Takano M,Morita K,Kadota E,Iizuka N,Maruyama H,Haratake J,Kojima Y,Ikeda N,Inatsugi N,Nonomura A

更新日期：2012-06-01 00:00:00

abstract：:An enzyme immunoassay technique based on the direct detection of Chlamydia trachomatis antigen in urethral or cervical swabs was used for the rapid diagnosis of chlamydial genital infection. Urethral and cervical samples from 140 patients were tested in parallel by enzyme immunoassay and cell culture using iodine stai...

journal_title：Journal of clinical pathology

authors： Mumtaz G,Mellars BJ,Ridgway GL,Oriel JD

更新日期：1985-07-01 00:00:00

abstract：:Nasal biopsy findings in malignant histiocytosis presenting clinically as lethal midline granuloma are characterised by necrosis and infiltration of atypical histiocytic cells with a diffuse positive reaction for non-specific esterase. This cellular character was common to midline malignant reticulosis, and midline ma...

journal_title：Journal of clinical pathology

authors： Aozasa K

更新日期：1982-06-01 00:00:00

abstract：:Adenocarcinoma of the anal glands is very rare but it is an important lesion to recognise as with early diagnosis, it has an excellent prognosis. Because it involves the submucosa widely and penetrates the mucosa late, it can be mistaken for metastatic gastrointestinal carcinoma, or tumour arising in sinuses and fistu...

journal_title：Journal of clinical pathology

authors： Behan WM,Burnett RA

更新日期：1996-12-01 00:00:00

abstract：:The ultrastructure of the osteocytes, osteoblasts, osteoclasts, haemopoietic and other connective tissue cells was examined in 27 biopsies from 22 patients with Paget's disease of bone. Electron microscopy showed characteristic nuclear and cytoplasmic inclusions in the osteoclasts of all of the 25 biopsies exhibiting ...

journal_title：Journal of clinical pathology

authors： Harvey L,Gray T,Beneton MN,Douglas DL,Kanis JA,Russell RG

更新日期：1982-07-01 00:00:00

abstract：:Common acute lymphoblastic leukaemia antigen (CALLA) was first characterised in lymphoid leukaemic cells. The antigen is present in different stages of lymphoid cell differentiation as well as in subsets of myeloid cells, and further studies have also shown its presence in non-lymphoid tissues. The recent cloning and ...

journal_title：Journal of clinical pathology

authors： Loke SL,Leung CY,Chiu KY,Yau WL,Cheung KN,Ma L

更新日期：1990-08-01 00:00:00

abstract：:The adhesion molecule E-cadherin is essential for maintaining epithelial intercellular adhesion. Loss or reduced expression of E-cadherin has been related to invasive behaviour in a wide range of carcinomas. Using immunoblotting techniques, the existence of multiple soluble forms of E-cadherin was demonstrated in urin...

journal_title：Journal of clinical pathology

authors： Banks RE,Porter WH,Whelan P,Smith PH,Selby PJ

更新日期：1995-02-01 00:00:00

abstract：:The ability of erythrocytes to synthesize porphyrins from delta-aminolaevulic acid was compared in healthy people, patients with true iron-deficiency anaemia, and anaemic patients with rheumatoid arthritis. Porphyrin synthesis was found to be impaired in true iron deficiency but not in rheumatoid arthritis cases showi...

journal_title：Journal of clinical pathology

authors： Gutniak O,Kopéc M,Nieczaj J

更新日期：1971-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the protein expression of connexin 43 (Cx43) in primary urothelial bladder cancer and test its association with the histopathological characteristics and clinical outcome. METHODS:A tissue microarray containing 348 tissue samples from 174 patients with primary urothelial carcinomas of the bladde...

journal_title：Journal of clinical pathology

authors： Poyet C,Buser L,Roudnicky F,Detmar M,Hermanns T,Mannhard D,Höhn A,Rüschoff J,Zhong Q,Sulser T,Moch H,Wild PJ

更新日期：2015-10-01 00:00:00

abstract：:A method for the neutron activation analysis of copper in biological material is described and applied to the diagnosis and management of four cases of Wilson's disease. Results obtained for serum and urine are in agreement with values obtained by established colorimetric techniques. The method described can estimate ...

journal_title：Journal of clinical pathology

authors： Fell GS,Smith H,Howie RA

更新日期：1968-01-01 00:00:00

abstract：:Serious infection caused by Lancefield group C streptococci is unusual in man. Two unrelated deaths associated with these organisms in a 55 year old woman who died after three days of diarrhoea and vomiting, and in a 65 old man who died after a week of non-specific symptoms, are presented. Post mortem examination show...

journal_title：Journal of clinical pathology

authors： Bateman AC,Ramsay AD,Pallett AP

更新日期：1993-10-01 00:00:00

abstract：:Activation of the complement system, the main humoral mediator of inflammation, is restrained by the action of enzyme inhibitors including alpha 1-antitrypsin. Deficiency leads to chronic liver disease in about one in five children with this genetic defect. Complement activation was investigated in 34 children with al...

journal_title：Journal of clinical pathology

authors： Littleton ET,Bevis L,Hansen LJ,Peakman M,Mowat AP,Mieli-Vergani G,Vergani D

更新日期：1991-10-01 00:00:00

abstract：:Several studies have recently documented the presence of persistently abnormal liver function tests in asymptomatic haemophiliacs. While the aetiology is unknown it is possible that repeated exposure to agents transmitted in blood products may be important. This study has attempted to determine the prevalence of viral...

journal_title：Journal of clinical pathology

authors： McVerry BA,Ross MG,Knowles WA,Voke J

更新日期：1979-04-01 00:00:00

abstract：AIMS:Marked thrombocytosis is uncommon in chronic myelogenous leukaemia (CML) but may be associated with mutation of JAK2 V617F, calreticulin (CALR) and/or phospho-STAT5 (p-STAT5) activation in other myeloproliferative neoplasms (MPNs), particularly essential thrombocythaemia (ET). We investigated the JAK2 V617F, CALR ...

journal_title：Journal of clinical pathology

authors： Turakhia SK,Murugesan G,Cotta CV,Theil KS

更新日期：2016-08-01 00:00:00

abstract：AIMS:The aim of this study was to develop a computer-aided diagnosis (CADx) system for identifying breast pathology. METHODS:Two sets of 100 consecutive core needle biopsy (CNB) specimens were collected for test and validation studies. All 200 CNB specimens were stained with antibodies targeting oestrogen receptor (ER...

journal_title：Journal of clinical pathology

authors： Maeda I,Kubota M,Ohta J,Shinno K,Tajima S,Ariizumi Y,Doi M,Oana Y,Kanemaki Y,Tsugawa K,Ueno T,Takagi M

更新日期：2017-12-01 00:00:00

abstract：:Expression profiling has been extensively applied to the study of breast cancer and undoubtedly is changing the way breast cancer is perceived. Over the past few years, several groups have described prognostic "signatures" (gene lists) that are purported to be more accurate prognostic factors than well established cli...

journal_title：Journal of clinical pathology

authors： Reis-Filho JS,Westbury C,Pierga JY

更新日期：2006-03-01 00:00:00

abstract：:This memorandum proposes a standardized system of reporting the histology of human lymph nodes based on commonly used simple staining techniques. The purpose is to provide a uniform, internationally acceptable system by which the histological structure of lymph nodes can be correlated with other parameters of immunolo...

journal_title：Journal of clinical pathology

authors： Cottier H,Turk J,Sobin L

更新日期：1973-05-01 00:00:00