A pilot study to demonstrate diagnostic potential of galectin-3 levels in saliva.

abstract：:In vitro morphological and functional studies were carried out on platelets which had been cryopreserved in the presence of 5% dimethyl sulphoxide (DMSO). Overall loss of platelets was around 50%. Those which survived freezing and reconstitution showed marked morphological deterioration, increase of procoagulant activ...

journal_title：Journal of clinical pathology

authors： Baythoon H,Tuddenham EG,Hutton RA

更新日期：1982-08-01 00:00:00

abstract：AIMS:Pim-1 is a serine/threonine kinase that has been shown to play an integral role in the development of a number of human cancers, such as haematolymphoid malignancies. Recently, evidence has shown Pim-1 to be important in prostatic carcinogenesis. In order to further our understanding of its role in prostate cancer...

journal_title：Journal of clinical pathology

authors： Cibull TL,Jones TD,Li L,Eble JN,Ann Baldridge L,Malott SR,Luo Y,Cheng L

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND/AIMS:Lymphocytic colitis is a clinicopathological entity characterised by protracted watery diarrhoea and an increased number of intraepithelial lymphocytes (IELs) in the surface epithelium of the colonic mucosa. This report describes two patients with symptoms similar to those of lymphocytic colitis and an ...

journal_title：Journal of clinical pathology

authors： Rubio CA,Lindholm J

更新日期：2002-02-01 00:00:00

abstract：AIMS:To study the localisation of the endothelial nitric oxide synthase (eNOS) in the normal placenta, with special emphasis on the implantation site in the first trimester of pregnancy, and in the different subtypes of trophoblastic cells in gestational trophoblastic disease. METHODS:The immunoperoxidase technique wi...

journal_title：Journal of clinical pathology

authors： Ariel I,Hochberg A,Shochina M

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Periostin is a secreted adhesion protein, normally expressed in mesenchime-derived cells. Aberrant expression of the periostin gene in epithelial tumours seems to play a role in angiogenesis and metastases. AIMS:To investigate periostin expression in a consecutive series of breast carcinomas and correlate i...

journal_title：Journal of clinical pathology

authors： Puglisi F,Puppin C,Pegolo E,Andreetta C,Pascoletti G,D'Aurizio F,Pandolfi M,Fasola G,Piga A,Damante G,Di Loreto C

更新日期：2008-04-01 00:00:00

abstract：AIMS:To assess the accuracy of the Mast-ID 15 system compared with API 20 E for the identification of stock and fresh clinical strains of Enterobacteriaceae and Acinetobacter spp; to compare the accuracy of 19 pin and 36 pin multipoint inoculator heads. METHODS:One hundred frozen stock cultures of Enterobacteriaceae a...

journal_title：Journal of clinical pathology

authors： Shakespeare AP,Megson GM,Jones PA,Drucker DB,Keaney MG,Ganguli LA

更新日期：1992-02-01 00:00:00

abstract：:The principles which should govern the planning of benching and services for new laboratories are enumerated. These include the necessity for long-term planning, flexibility, and economy. The ;Cardiff benching system' where the benches are composed of units that consist of an independent movable table base, a removabl...

journal_title：Journal of clinical pathology

authors： LAURENCE KM

更新日期：1963-09-01 00:00:00

abstract：:The Scottish Meningococcus and Pneumococcus Reference Laboratory provides a national service for the laboratory confirmation of meningococcal and pneumococcal disease in Scotland. The main tests used for the laboratory confirmation of meningococcal disease are culture, the polymerase chain reaction (PCR), antibody tes...

journal_title：Journal of clinical pathology

authors： Clarke SC,Diggle MA,Reid JA,Thom L,Edwards GF

更新日期：2001-07-01 00:00:00

abstract：:Sixty six women with first or second trimester fetal loss were investigated for the presence of lupus anticoagulant by routine coagulation tests and the dilute Russell's viper venom time with a platelet neutralisation procedure, and for raised anticardiolipin antibodies by an enzyme linked immunosorbent assay. Of 35 w...

journal_title：Journal of clinical pathology

authors： Creagh MD,Malia RG,Cooper SM,Smith AR,Duncan SL,Greaves M

更新日期：1991-01-01 00:00:00

abstract：:Squamous cell carcinoma arising in ovarian endometriosis is extremely rare, but a case is reported in a 62 year old woman. If such an ovarian tumour is discovered evidence of teratoma, Brenner tumour, or endometriosis should be sought. Extensive sampling is mandatory as the developing tumour often overgrows the foci o...

journal_title：Journal of clinical pathology

authors： Naresh KN,Ahuja VK,Rao CR,Mukherjee G,Bhargava MK

更新日期：1991-11-01 00:00:00

abstract：AIMS:To validate a method of assessment of low hepatic iron concentration based on a biochemical colorimetric assay plus histological scoring. METHODS:The within-day and day to day precision of the iron colorimetric assay was determined on frozen rat liver. The coefficient of variation (CV) of iron measurement in two ...

journal_title：Journal of clinical pathology

authors： Imbert-Bismut F,Charlotte F,Turlin B,Khalil L,Piton A,Brissot P,Le Charpentier Y,Delattre J,Opolon P,Deugnier Y,Poynard T

更新日期：1999-06-01 00:00:00

abstract：:Veno-occlusive disease of the liver with clinical and pathological features similar to those of the condition occurring in the Caribbean is described in a young woman resident in Britain. The diagnosis was made from liver biopsies and hepatic venography and was confirmed at necropsy. Small amounts of pyrroliziding alk...

journal_title：Journal of clinical pathology

authors： McGee J,Patrick RS,Wood CB,Blumgart LH

更新日期：1976-09-01 00:00:00

abstract：:Two cases of peritoneal granulomatous reactions to food starch are described. They followed bowel perforation and clinically mimicked tuberculous and glove-powder starch peritonitis. Their histological differences from corn-starch peritonitis warrant attention in the absence of previous documentation of starch as a co...

journal_title：Journal of clinical pathology

authors： Davies JD,Ansell ID

更新日期：1983-04-01 00:00:00

abstract：:A rapidly fatal case of enteritis necroticans in a 24 year old man with diabetes was caused by Clostridium perfringens type C. The role of beta toxin in the disease is discussed. This type has not been previously described as a causative agent in necrotising bowel disease of man outside endemic areas. ...

journal_title：Journal of clinical pathology

authors： Severin WP,de la Fuente AA,Stringer MF

更新日期：1984-08-01 00:00:00

abstract：:This report describes a left adrenal tumour in a 16 year old Chinese girl who presented with fever of unknown origin. The histological and ultrastructural features of the adrenal tumour were those of a primitive small round cell tumour with neuroendocrine differentiation. Cytogenetic analysis of cultured tumour cells ...

journal_title：Journal of clinical pathology

authors： Lam KY,Lo CY,Shek TW,Ma ES,Au WY,Chan GC

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Chromogenic in situ hybridisation (CISH) is an alternative to immunohistochemistry or FISH for the assessment of HER2 oncogene status in breast cancer. Although CISH is being used increasingly in routine diagnostics, there are no established inter-laboratory quality assurance programmes for this test. METHO...

journal_title：Journal of clinical pathology

authors： Di Palma S,Collins N,Bilous M,Sapino A,Mottolese M,Kapranos N,Schmitt F,Isola J

更新日期：2008-06-01 00:00:00

abstract：AIMS:Cryptogenic organising pneumonia (COP) and acute fibrinous and organising pneumonia (AFOP) are recognised patterns of organising pneumonia (OP), a condition that resembles pneumonia but is not caused by infection. We have recognised granulomatous organising pneumonia (GOP) to be a similar histopathological entity ...

journal_title：Journal of clinical pathology

authors： Feinstein MB,DeSouza SA,Moreira AL,Stover DE,Heelan RT,Iyriboz TA,Taur Y,Travis WD

更新日期：2015-06-01 00:00:00

abstract：:Tumour tissue from 29 patients with primary brain lymphoma was reviewed to determine if there was an aetiological association between Epstein-Barr virus and polyclonal and monoclonal lymphoproliferations. The morphology and immunophenotype in 24 patients for whom paraffin wax embedded tissue was available were studied...

journal_title：Journal of clinical pathology

authors： Murphy JK,Young LS,Bevan IS,Lewis FA,Dockey D,Ironside JW,O'Brien CJ,Wells M

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Hepatic fibrosis is one of the main consequences of liver disease. Both fibrosis and steatosis may be seen in some patients with chronic hepatitis C and alcoholic liver disease (ALD). AIMS:To quantitate fibrosis and steatosis by stereological and morphometric techniques in patients with chronic hepatitis C ...

journal_title：Journal of clinical pathology

authors： Zaitoun AM,Al Mardini H,Awad S,Ukabam S,Makadisi S,Record CO

更新日期：2001-06-01 00:00:00

abstract：:One hundred and seventyone antenatal patients were examined for the presence of ;large colony' mycoplasmas in the vagina, and for complement-fixing antibody to Mycoplasma hominis. In 25 patients the findings before and after delivery were compared. In patients from whom M. hominis was grown, antibody was twice as comm...

journal_title：Journal of clinical pathology

authors： Jones DM

更新日期：1967-07-01 00:00:00

abstract：:During a two-year period of observation Bacteroides species were isolated from specimens of pus and vaginal swabs from 115 patients in this hospital. Thirty-five representative strains proved on examination to be Bacteroides fragilis. Minimal inhibitory and minimal bactericidal concentrations of six antibiotics for th...

journal_title：Journal of clinical pathology

authors： Ingham HR,Selkon JB,Codd AA,Hale JH

更新日期：1968-07-01 00:00:00

abstract：:An inhibitor of plasminogen activator has been identified in human platelets by the technique of sodium dodecyl sulphate polyacrylamide gel electrophoresis and zymography. The inhibitor has a molecular weight of about 40 000 and is distinct from known plasma protease inhibitors. It is associated almost exclusively wit...

journal_title：Journal of clinical pathology

authors： Booth NA,Anderson JA,Bennett B

更新日期：1985-07-01 00:00:00

abstract：:The ability of erythrocytes to synthesize porphyrins from delta-aminolaevulic acid was compared in healthy people, patients with true iron-deficiency anaemia, and anaemic patients with rheumatoid arthritis. Porphyrin synthesis was found to be impaired in true iron deficiency but not in rheumatoid arthritis cases showi...

journal_title：Journal of clinical pathology

authors： Gutniak O,Kopéc M,Nieczaj J

更新日期：1971-05-01 00:00:00

abstract：:A comparison of Skirrow's, Butzler's, Blaser's, Campy-BAP and Preston media for Campylobacter spp was made using human, animal and environmental specimens. Butzler's medium gave the lowest isolation rate and Preston medium, which was the most selective, the highest isolation rate. Enrichment culture using Preston enri...

journal_title：Journal of clinical pathology

authors： Bolton FJ,Coates D,Hinchliffe PM,Robertson L

更新日期：1983-01-01 00:00:00

abstract：INTRODUCTION:Whole slide images (WSI) have been used in many pathology applications such as teleconsultation, teaching and research, but not in primary diagnostics. The aim of this study was to test the feasibility of using WSI in primary diagnostics of paediatric pathology specimens and placental tissue. MATERIALS AN...

journal_title：Journal of clinical pathology

authors： Al-Janabi S,Huisman A,Nikkels PG,ten Kate FJ,van Diest PJ

更新日期：2013-03-01 00:00:00

abstract：:Immune and non-immune rubella sera were examined in the haemagglutination inhibition (HAI) test to evaluate the removal of lipoprotein non-specific inhibitors (NSI) of haemagglutination after kaolin and manganous chloride/heparin treatments. The sera were titrated fresh or after lipoprotein deterioration brought about...

journal_title：Journal of clinical pathology

authors： Shortridge KF

更新日期：1977-05-01 00:00:00

abstract：:In an era when immunohistochemistry (IHC) is increasingly depended on for histological subtyping, and IHC-determined biomarker informing rapid treatment choices is on the horizon; reproducible, quantifiable techniques are required. This study aimed to compare automated IHC scoring to quantify 6 DNA damage response pro...

journal_title：Journal of clinical pathology

authors： Gentles L,Howarth R,Lee WJ,Sharma-Saha S,Ralte A,Curtin N,Drew Y,O'Donnell RL

更新日期：2020-11-19 00:00:00

abstract：:In four persons of one family the existence of an enzymatic defect, presumably consisting of a deficiency of glutaminase in the cells of the renal tubules, is postulated, and is implied by a reduced elimination of ammonia in the urine, by a relatively low urinary pH, and by its increased titratable acidity. The most c...

journal_title：Journal of clinical pathology

authors： KRAWCZYNSKI J,SAGAN Z,WALAJTYS E,ILOWIECKA K

更新日期：1965-03-01 00:00:00

abstract：:A case of bilateral gonadoblastoma/dysgerminoma in a 46 XY phenotypical female is presented. Increased circulating beta human chorionic gonadotropin (beta-HCG) and testosterone together with a decreased concentration of follicle stimulating hormone (FSH) reflected the activities of these tumours. The patient is alive ...

journal_title：Journal of clinical pathology

authors： Fisher RA,Salm R,Spencer RW

更新日期：1982-04-01 00:00:00

abstract：:One hundred cases of transitional cell carcinoma of the bladder were studied to determine whether squamous metaplasia and other histological features within the bladder can be of value in predicting outcome of treatment with radiotherapy. Sixty cases showed the changes of squamous metaplasia, and of this group 46 (78%...

journal_title：Journal of clinical pathology

authors： Martin JE,Jenkins BJ,Zuk RJ,Blandy JP,Baithun SI

更新日期：1989-03-01 00:00:00