Rubella virus serology:detection of residual lipoprotein inhibitors of haemagglutination using sensitive indicator arboviruses.

abstract：AIMS:Marked thrombocytosis is uncommon in chronic myelogenous leukaemia (CML) but may be associated with mutation of JAK2 V617F, calreticulin (CALR) and/or phospho-STAT5 (p-STAT5) activation in other myeloproliferative neoplasms (MPNs), particularly essential thrombocythaemia (ET). We investigated the JAK2 V617F, CALR ...

journal_title：Journal of clinical pathology

authors： Turakhia SK,Murugesan G,Cotta CV,Theil KS

更新日期：2016-08-01 00:00:00

abstract：:Thirty two fire victims with smoke inhalation, with or without burns, and 26 control subjects had bronchoalveolar lavage performed. Cell yields and differential cell counts were assessed. All patients and controls were cigarette smokers. Patients with smoke inhalation (SI) injury generally showed higher total bronchoa...

journal_title：Journal of clinical pathology

authors： Riyami BM,Tree R,Kinsella J,Clark CJ,Reid WH,Campbell D,Gemmell CG

更新日期：1990-01-01 00:00:00

abstract：AIM:The evaluation of allelic losses at the FHIT and the BRCA1 genes and at three other loci at the 17q region in a series of 34 sporadic breast cancer cases from Southern Brazil. METHODS:The samples were evaluated for loss of heterozygosity (LOH) at the FHIT and the BRCA1 genes and at three other microsatellite marke...

journal_title：Journal of clinical pathology

authors： Santos SC,Cavalli LR,Cavalli IJ,Lima RS,Haddad BR,Ribeiro EM

更新日期：2004-04-01 00:00:00

abstract：AIM:The immunoproteasome is a specific proteasome isoform whose proteolytic activity enhances the generation of antigenic peptides to be presented by major histocompatibility complex class I molecules to CD8+ T cells. Physiologically, it is expressed abundantly in immune cells and is induced in somatic cells by cytokin...

journal_title：Journal of clinical pathology

authors： Kiuchi T,Tomaru U,Ishizu A,Imagawa M,Iwasaki S,Suzuki A,Otsuka N,Ohhara Y,Kinoshita I,Matsuno Y,Dosaka-Akita H,Kasahara M

更新日期：2020-09-17 00:00:00

abstract：:A "Centrifichem" centrifugal analyser was found using a double fluorescence/bacterial tracer method to be a source of airborne and surface contamination in the laboratory. The airborne contamination was controlled by a modification incorporating a filter. Ubiquitous surface contamination generally accompanied the proc...

journal_title：Journal of clinical pathology

authors： Kennedy DA,Stevens JF,Horn AN

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Peutz-Jeghers syndrome (PJS) is an autosomal dominant hamartomatous polyposis syndrome of the gastrointestinal tract, caused by a germline STK11/LKB1 mutation. Nasal polyposis was described in the original report by Peutz. Recently, a molecular-genetic association between nasal polyposis and PJS has been rep...

journal_title：Journal of clinical pathology

authors： de Leng WW,Westerman AM,Weterman MA,Jansen M,van Dekken H,Giardiello FM,de Rooij FW,Paul Wilson JH,Offerhaus GJ,Keller JJ

更新日期：2007-04-01 00:00:00

abstract：:The epithelium of the human fallopian tube (oviduct) and cervix were studied by histological, immunohistological, and ultrastructural methods with a view to establishing the nature of the so called "basal" and "reserve" cells. The results indicated that the "basal" cells of the oviductal epithelia were T lymphocytes, ...

journal_title：Journal of clinical pathology

authors： Peters WM

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterised by the presence of various laboratory abnormalities but the precise role of laboratory staff in initiating clinical referral and subsequent biopsy is not clear. OBJECTIVE:To examine the impact of laboratory abnormalities in the inv...

journal_title：Journal of clinical pathology

authors： Sinclair D,Spedding A,Young R

更新日期：2006-04-01 00:00:00

abstract：:Fifteen cases of large-cell lymphoma, diagnosed as centroblastic (5), B-immunoblastic (5) or true histiocytic (5). lymphoma and one case of malignant histiocytosis were studied with monoclonal antibodies. Each diagnosis was based on morphological as well as marker studies. A panel of monoclonal and heterologous antibo...

journal_title：Journal of clinical pathology

authors： van der Valk P,van den Besselaar-Dingjan G,Daha MR,Meijer CJ

更新日期：1983-01-01 00:00:00

abstract：AIMS:Primary cilia play an important role in the regulation of cell signalling pathways and are thought to have a role in cancer but have seldom been studied in human cancer samples. METHODS:Primary cilia were visualised by dual immunofluorescence for anti-CROCC (ciliary rootlet coiled-coil) and anti-tubulin in a rang...

journal_title：Journal of clinical pathology

authors： Yasar B,Linton K,Slater C,Byers R

更新日期：2017-07-01 00:00:00

abstract：:The proportion of fimbriate strains amongst Escherichia coli freshly isolated from infected urines did not differ significantly from the proportion amongst commensal Esch. coli isolated from the bowel and from non-infected urines. It is concluded that fimbriae play no major role in the pathogenesis of Esch. coli urina...

journal_title：Journal of clinical pathology

authors： Buck AC

更新日期：1967-01-01 00:00:00

abstract：:The separation of mesothelial hyperplasia from early malignant mesothelioma remains one of the most difficult problems in histopathology. Inconclusive cases are termed "atypical mesothelial hyperplasia" and treated expectantly. A 49 year old male pipeline engineer was diagnosed as having atypical mesothelial hyperplas...

journal_title：Journal of clinical pathology

authors： Scurry J,Duggan MA

更新日期：1999-07-01 00:00:00

abstract：:In vitro morphological and functional studies were carried out on platelets which had been cryopreserved in the presence of 5% dimethyl sulphoxide (DMSO). Overall loss of platelets was around 50%. Those which survived freezing and reconstitution showed marked morphological deterioration, increase of procoagulant activ...

journal_title：Journal of clinical pathology

authors： Baythoon H,Tuddenham EG,Hutton RA

更新日期：1982-08-01 00:00:00

abstract：AIMS:To evaluate the prognostic impact of the width of negative surgical margins (NSM) and associated and preinvasive lesions at the NSM in patients with penile squamous cell cancer (PSC). METHODS:Enrolling 87 patients with NSM who underwent surgery for PSC, the archived margin slides and entirely wax-embedded surgica...

journal_title：Journal of clinical pathology

authors： Gunia S,Koch S,Jain A,May M

更新日期：2014-03-01 00:00:00

abstract：:The placenta is the fetal organ providing the interchange between mother and fetus. This organ needs to provide its function such as transport and secretion even during its development and thus all developmental changes need to be in accordance with its function. This review describes development of the placenta durin...

journal_title：Journal of clinical pathology

authors： Huppertz B

更新日期：2008-12-01 00:00:00

abstract：:Renal endocrine tumours are extremely rare, and carcinoid tumoral elements in renal cell carcinoma have never been reported. This is the first report of a composite renal cell carcinoma containing a clear cell renal cell carcinoma associated with carcinoid tumoral elements, in a patient with synchronous metastatic dis...

journal_title：Journal of clinical pathology

authors： Bressenot A,Delaunay C,Gauchotte G,Oliver A,Boudrant G,Montagne K

更新日期：2010-02-01 00:00:00

abstract：:Serum total calcium was measured in 1693 patients during a four-month period. We examined the effects of adjustment for albumin concentration on the interpretation of single measurements of serum total calcium and on the variation of series of measurements in individual patients. Markedly abnormal total calcium concen...

journal_title：Journal of clinical pathology

authors： Payne RB,Carver ME,Morgan DB

更新日期：1979-01-01 00:00:00

abstract：:A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in gamma globulin was also noted from the...

journal_title：Journal of clinical pathology

authors： RAWSTRON JR,FARTHING CP

更新日期：1962-03-01 00:00:00

abstract：AIMS:To investigate the association of cagA positivity and non-opsonic neutrophil activation capacity in wild-type Helicobacter pylori strains with peptic ulcer disease or chronic gastritis only. METHODS:Helicobacter pylori were isolated from antral biopsies of 53 consecutive patients with chronic antral gastritis, of...

journal_title：Journal of clinical pathology

authors： Danielsson D,Farmery SM,Blomberg B,Perry S,Rautelin H,Crabtree JE

更新日期：2000-04-01 00:00:00

abstract：:The cytological features of testicular germ cell tumours were established in smears from 15 freshly resected tumours. These features were applied to the fine needle aspiration cytology diagnosis of metastases in 27 patients referred for chemotherapy. There were 16 positive reports in 32 aspirates of which 13 were take...

journal_title：Journal of clinical pathology

authors： Highman WJ,Oliver RT

更新日期：1987-11-01 00:00:00

abstract：:Splenic pathology was analysed in 73 patients with immune thrombocytopenic purpura who underwent splenectomy for bleeding that had been resistant to adrenocorticosteroids. The mean splenic weight was 100 g. The only notable macroscopic feature was the prominence of Malpighian corpuscles in 15 cases. Microscopic examin...

journal_title：Journal of clinical pathology

authors： Hayes MM,Jacobs P,Wood L,Dent DM

更新日期：1985-09-01 00:00:00

abstract：:In studies using indirect immunofluorescence IgG antibodies to Clostridium perfringens were found in sera from healthy adults. Sera from 236 healthy children were examined. The normally occurring IgG antibodies to C perfringens were found to have an age related variation. Preliminary data suggest that they are not cor...

journal_title：Journal of clinical pathology

authors： Zarén E,Schwan A,Frenckner B

更新日期：1987-03-01 00:00:00

abstract：AIM:Recent events surrounding postmortem practices have necessitated several changes in the way necropsies are conducted both within the medicolegal and hospital settings. These changes have resulted in a striking reduction in the frequency of brain retention for neuropathological examination. Aberdeen Royal Infirmary,...

journal_title：Journal of clinical pathology

authors： Sharma M,Grieve JH

更新日期：2006-04-01 00:00:00

abstract：:A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

journal_title：Journal of clinical pathology

authors： Green NE

更新日期：1979-06-01 00:00:00

abstract：:The mean areas of lymphoid follicles have been determined in 20 specimens of malignant follicular (centrocytic-centroblastic) lymphoma, 15 specimens of reactive follicular hyperplasia and 10 palatine tonsils. In all of the benign specimens and whenever possible for those showing malignancy, the areas of both the whole...

journal_title：Journal of clinical pathology

authors： Crocker J,Jones EL,Curran RC

更新日期：1983-09-01 00:00:00

abstract：:The sensitivity patterns to a number of antibiotic-impregnated discs of 126 strains of Gram-negative anaerobes and 36 strains of Gram-positive non-sporing anaerobes from various sources have been examined. The sensitivity patterns shown by Bacteroids fragilis and Bacteroides melaninogenicus were useful for the rapid i...

journal_title：Journal of clinical pathology

authors： Peach S

更新日期：1975-05-01 00:00:00

abstract：:Laboratory studies on clotrimazole showed that it had marked activity in vitro against all the Candida spp. and Cryptococcus spp. tested, against almost all strains of dermatophytes, and against Aspergillus spp and other fungal genera responsible for systemic mycoses; it had limited activity towards Gram-positive bact...

journal_title：Journal of clinical pathology

authors： Holt RJ,Newman RL

更新日期：1972-12-01 00:00:00

abstract：:As part of a study to establish the prevalence of renal calculus disease, alkaline phosphatase activity was measured by the method recommended by the Scandinavian Society for Clinical Chemistry and Clinical Physiology in the plasma of 3823 adults from the Scottish new town of Cumbernauld. The enzyme activity differs i...

journal_title：Journal of clinical pathology

authors： Gardner MD,Scott R

更新日期：1978-12-01 00:00:00

abstract：AIMS:As part of the UK antimicrobial resistance strategy and action plan, the Public Health Laboratory Service (PHLS) is required to collect antibiotic susceptibility data so that resistance trends and patterns can be monitored. Most laboratories report urine Gram negative isolates, as "coliforms" according to morpholo...

journal_title：Journal of clinical pathology

authors： Fallon D,Andrews N,Frodsham D,Gee B,Howe S,Iliffe A,Nye KJ,Warren RE

更新日期：2002-07-01 00:00:00

abstract：:The costs of a clinical chemistry laboratory in a district general hospital were studied. The system used has certain advantages over the conventional Cooper Lybrand method. The time taken by technicians to perform tests was more variable than expected and the cost of sample collection was higher than process-cost for...

journal_title：Journal of clinical pathology

authors： Stilwell JA

更新日期：1981-06-01 00:00:00