Examination of breast needle core biopsy specimens performed for screen-detected microcalcification.

abstract：:By means of enzyme immunoassays based on two monoclonal antibodies with specificities for distinct forms of placental type alkaline phosphatase (Pl-ALP), together with L-leucine inhibition studies, it has been possible to distinguish the Nagao type carcinoplacental enzyme from other placental type alkaline phosphatase...

journal_title：Journal of clinical pathology

authors： McLaughlin PJ,Twist AM,Evans CC,Johnson PM

更新日期：1984-07-01 00:00:00

abstract：:A rare case of adult onset Langerhans' cell histiocytosis associated with dysgerminoma in a 35 year old Chinese woman is reported. The patient had a history of dysgerminoma of left ovary 15 years previously and had undergone surgery followed by radiotherapy and an uneventful recovery. She presented again in March 1994...

journal_title：Journal of clinical pathology

authors： Ng WK,Lam KY,Ng IO

更新日期：1995-10-01 00:00:00

abstract：AIMS:To determine whether the presence of disseminated bone marrow tumour cells at diagnosis is a prognostic factor for breast cancer patients at high risk of recurrence or bone metastasis, and to assess their presence as a criterion for evaluation of the potential benefits of adjuvant chemotherapy. METHODS:Multiple b...

journal_title：Journal of clinical pathology

authors： Lagrange M,Ferrero JM,Lagrange JL,Machiavello JC,Monticelli J,Bayle C,Creisson A,Namer M,Thyss A,Bourcier C,Gioanni J,Schneider M

更新日期：1997-03-01 00:00:00

abstract：:The sensitivity of methods to detect antibodies to intrinsic factor was assessed. Five sera of known antibody content were tested in 31 laboratories and 30 sera from patients with pernicious anaemia were tested in one laboratory. Five non-commercial methods and two kits for type I antibodies and one non-commercial met...

journal_title：Journal of clinical pathology

authors： Shackleton PJ,Fish DI,Dawson DW

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Although Bulgaria has one of the highest rates of cervical cancer incidence and mortality in the EU, data on HPV type distribution are limited. AIM:To determine the prevalence of HPV types 16 and 18 in archival specimens from cervical cancer cases from Bulgaria. METHODS:A total of 145 formalin-fixed, paraf...

journal_title：Journal of clinical pathology

authors： Todorova I,Ganchev G,Shikova E

更新日期：2010-12-01 00:00:00

abstract：:A method is described for the separation and determination of individual bile acids in serum and in intestinal contents, employing thin-layer chromatography and fluorimetry. The mean recovery from intestinal juice was 94% and from serum 82%. Normal values for the individual bile acids of serum and examples of clinical...

journal_title：Journal of clinical pathology

authors： Panveliwalla D,Lewis B,Wootton ID,Tabaqchali S

更新日期：1970-05-01 00:00:00

abstract：:Idoxuridine-treated McCoy cells grown as monolayers in 96 well microplates provide a convenient method for the isolation of Chlamydia trachomatis. Staining of infected monolayers with periodic acid-Schiff reagent (PAS) allows easy recognition of C trachomatis inclusions without the need for dark-ground microscopy. By ...

journal_title：Journal of clinical pathology

authors： Mallinson H,Sikotra S,Arya OP

更新日期：1981-07-01 00:00:00

abstract：:A case of florid rheumatoid heart disease with complete heart block is described, and the histopathology of the atrioventricular conducting tissue is described in detail. ...

journal_title：Journal of clinical pathology

authors： Harris M

更新日期：1970-10-01 00:00:00

abstract：:Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...

journal_title：Journal of clinical pathology

authors： Booth SN,Lakin G,Dykes PW,Burnett D,Bradwell AR

更新日期：1977-06-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：AIMS:The authors previously demonstrated that nasal mucus cyclic adenosine 3', 5'-monophosphate (cAMP) and cyclic 3', 5'-guanosine monophosphate (cGMP) were lower in patients with smell and taste dysfunction than in normal individuals. To learn more about these differences this study related levels of nasal mucus cAMP ...

journal_title：Journal of clinical pathology

authors： Henkin RI,Velicu I

更新日期：2012-05-01 00:00:00

abstract：:A "Centrifichem" centrifugal analyser was found using a double fluorescence/bacterial tracer method to be a source of airborne and surface contamination in the laboratory. The airborne contamination was controlled by a modification incorporating a filter. Ubiquitous surface contamination generally accompanied the proc...

journal_title：Journal of clinical pathology

authors： Kennedy DA,Stevens JF,Horn AN

更新日期：1988-11-01 00:00:00

abstract：:The arrangement of the T cell receptor and immunoglobulin genes was analysed in lymphoid tissue biopsy specimens from 25 cases of angioimmunoblastic lymphadenopathy. Nineteen cases showed a rearrangement of the gene coding for the beta chain of the T cell receptor, and in one case a clonal rearrangement of immunoglobu...

journal_title：Journal of clinical pathology

authors： O'Connor NT,Crick JA,Wainscoat JS,Gatter KC,Stein H,Falini B,Mason DY

更新日期：1986-11-01 00:00:00

abstract：AIMS:To investigate the serological cross reaction between legionella and campylobacter using the rapid microagglutination test (RMAT). METHODS:Serum samples from 49 patients with campylobacter infection were tested for legionella antibodies using the indirect fluorescent antibody test (IFAT) and the RMAT. Serum sampl...

journal_title：Journal of clinical pathology

authors： Boswell TC

更新日期：1996-07-01 00:00:00

abstract：:The costs of a clinical chemistry laboratory in a district general hospital were studied. The system used has certain advantages over the conventional Cooper Lybrand method. The time taken by technicians to perform tests was more variable than expected and the cost of sample collection was higher than process-cost for...

journal_title：Journal of clinical pathology

authors： Stilwell JA

更新日期：1981-06-01 00:00:00

abstract：:In order to determine the cellular distribution of androgen receptors (AR) in normal liver and to examine whether phenotypic changes occur in a variety of non-neoplastic liver diseases, cryostat sections of explanted livers removed from 52 consecutive patients undergoing orthotopic transplantation were immunostained u...

journal_title：Journal of clinical pathology

authors： Hinchliffe SA,Woods S,Gray S,Burt AD

更新日期：1996-05-01 00:00:00

abstract：:Twenty-two known strains of the Bacteroides fragilis group of organisms and 67 clinical specimens from a variety of sites were examined by fluorescent antibody test (IFA) using two different antisera fro the rapid detection of B fragilis group of organisms. A previously reported Barts' pooled antisera was compared wit...

journal_title：Journal of clinical pathology

authors： Wills A,Taylor E,Pantosti A,Phillips I,Tabaqchali S

更新日期：1982-03-01 00:00:00

abstract：:The indirect immunofluorescence technique was used to study the expression of the blood group A and H antigens in fresh-frozen and formalin-fixed paraffin-embedded sections of the bladder mucosa of 21 patients with non-neoplastic diseases of the bladder. Reliable assessment of these antigens could only be made using c...

journal_title：Journal of clinical pathology

authors： Thorpe SJ,Abel P,Slavin G,Feizi T

更新日期：1983-08-01 00:00:00

abstract：AIMS:Although the autopsy is still the gold standard for quality assessment of clinical diagnoses, autopsy rates have been declining over the last decades to <10%. The aim of this study was to investigate the value of autopsies in the high-tech medicine era by determining the frequency of discrepancies between clinical...

journal_title：Journal of clinical pathology

authors： Kuijpers CC,Fronczek J,van de Goot FR,Niessen HW,van Diest PJ,Jiwa M

更新日期：2014-06-01 00:00:00

abstract：:A method for the neutron activation analysis of copper in biological material is described and applied to the diagnosis and management of four cases of Wilson's disease. Results obtained for serum and urine are in agreement with values obtained by established colorimetric techniques. The method described can estimate ...

journal_title：Journal of clinical pathology

authors： Fell GS,Smith H,Howie RA

更新日期：1968-01-01 00:00:00

abstract：BACKGROUND:Serine peptidase inhibitor Kazal type-1 (SPINK1), a trypsin kinase inhibitor, has well established associations with inflammation, cancer cell proliferation and carcinogenesis. However, the role of SPINK1 has not been investigated in stage IV colorectal cancer (CRC) patients receiving cetuximab based targete...

journal_title：Journal of clinical pathology

authors： Chen YT,Tsao SC,Tsai HP,Wang JY,Chai CY

更新日期：2016-04-22 00:00:00

abstract：AIMS:To develop a quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) for severe acute respiratory syndrome coronavirus (SARS-CoV) detection and explore the potential of using glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA as an internal control to exclude false negative results. METHODS:SAR...

journal_title：Journal of clinical pathology

authors： Wong SC,Chan JK,Lee KC,Lo ES,Tsang DN

更新日期：2005-03-01 00:00:00

abstract：AIMS:To study the localisation of the endothelial nitric oxide synthase (eNOS) in the normal placenta, with special emphasis on the implantation site in the first trimester of pregnancy, and in the different subtypes of trophoblastic cells in gestational trophoblastic disease. METHODS:The immunoperoxidase technique wi...

journal_title：Journal of clinical pathology

authors： Ariel I,Hochberg A,Shochina M

更新日期：1998-06-01 00:00:00

abstract：:The mechanism of DNA degradation and its clinical applications were examined. When purified lambda phage and extracted liver DNA were fixed in phosphate buffered formaldehyde, the DNA did not degrade, but there was incomplete digestion with endonuclease. Rat liver tissues were fixed under various conditions and DNA ex...

journal_title：Journal of clinical pathology

authors： Tokuda Y,Nakamura T,Satonaka K,Maeda S,Doi K,Baba S,Sugiyama T

更新日期：1990-09-01 00:00:00

abstract：:Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years and there is growing evidence from validation studies that WSI is comparable to glass slides for histopathology diagnosis, although with some limitations, which can be appropriately minimised. Whether the...

journal_title：Journal of clinical pathology

authors： Cheng CL,Tan PH

更新日期：2017-05-01 00:00:00

abstract：:A cytochemical study of the lysosomal enzyme beta-glucuronidase in 60 cases of acute leukaemia has shown a qualitative difference in the cytoplasmic distribution of the enzyme between blast cells of the lymphoid and myeloid cell series. This difference provides a useful additional method for cytochemical classificatio...

journal_title：Journal of clinical pathology

authors： Mann JR,Simpson JS,Munkley RM,Stuart J

更新日期：1971-12-01 00:00:00

abstract：BACKGROUND:RCAS1 (receptor binding cancer antigen expressed on SiSo cells) is a tumour associated antigen. It is involved in immune evasion by tumour cells, by binding to receptors on cells involved in the immune response, such as T cells and natural killer cells, and inducing apoptosis. High expression of RCAS1 has be...

journal_title：Journal of clinical pathology

authors： Leelawat K,Watanabe T,Nakajima M,Tujinda S,Suthipintawong C,Leardkamolkarn V

更新日期：2003-10-01 00:00:00

abstract：:Partial myoepithelial differentiation is common in simple epithelial hyperplasia (epitheliosis) of the breast but functional myoepithelial differentiation with basement membrane production is exceedingly rare. A peculiar change of hyaline globules within benign epithelial hyperplasia has been recognised before as "col...

journal_title：Journal of clinical pathology

authors： Wells CA,Wells CW,Yeomans P,Viña M,Jordan S,d'Ardenne AJ

更新日期：1990-11-01 00:00:00

abstract：:The immunofluorescent examination of nasopharyngeal secretions has been compared with conventional cell culture for the diagnosis of respiratory syncytial (RS) virus infection in children under the age of 2 years in Newcastle upon Tyne and Manchester. Two hundred and sixty-eight identifications of RS virus were made b...

journal_title：Journal of clinical pathology

authors： Cradock-Watson JE,McQuillin J,Gardner PS

更新日期：1971-05-01 00:00:00

abstract：:A locally developed, computer-based clinical chemistry laboratory system has been in operation since 1970. This utilises a Digital Equipment Co Ltd PDP 12 and an interconnected PDP 8/F computer. Details are presented of the performance and quality control techniques incorporated into the system. Laboratory performance...

journal_title：Journal of clinical pathology

authors： Undrill PE,Frazer SC

更新日期：1979-02-01 00:00:00