Non-specifically labelled cells that simulate bone marrow metastases in patients with non-metastatic breast cancer.

abstract：:Serum and tissue hepatitis B virus (HBV) markers were compared in 35 alcoholic and 23 non-alcoholic subjects affected by chronic liver disease. Seventeen point one per cent of alcoholic and 21.7% of non-alcoholic subjects had HBV tissue markers, but not serum markers, for this virus. It is therefore concluded that sho...

journal_title：Journal of clinical pathology

authors： Cuccurullo L,Rambaldi M,Iaquinto G,Ferraraccio F,Ambrosone L,Giardullo N,De Vita A

更新日期：1987-02-01 00:00:00

abstract：:A case of acute myelomonocytic leukaemia (AMMOL) is reported in which skin infiltration with xanthomatous nodules was the presenting feature. The histological, including ultrastructural, appearances are described. ...

journal_title：Journal of clinical pathology

authors： O'Donnell JR,Tansey P,Chung P,Burnett AK,Thomson J,McDonald GA

更新日期：1982-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) replication is reported in both tumour and non-tumour tissue in a case of hepatocellular carcinoma. Viral replication was established by showing the presence of minus strand HCV RNA by PCR amplification, after excluding residual reverse transcriptase activity of Taq polymerase. No minus strand ...

journal_title：Journal of clinical pathology

authors： Niu J,Kumar U,Monjardino J,Goldin R,Rosin D,Thomas HC

更新日期：1995-09-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) testing is required for newly diagnosed breast cancer and advised for recurrent and metastatic breast cancer, to determine treatment planning using HER2-directed therapy in the neoadjuvant, adjuvant and advanced disease settings. Wide variation, nationally, in the turnar...

journal_title：Journal of clinical pathology

authors： Shaaban AM,Purdie CA,Bartlett JM,Stein RC,Lane S,Francis A,Thompson AM,Pinder SE,Translational Subgroup of the NCRI Breast Clinical Studies Group.

更新日期：2014-02-01 00:00:00

abstract：:Prostaglandin E(2) (PGE(2)) was infused intravenously to eight women for the termination of pregnancy and tests of platelet function: coagulation and fibrinolysis were studied before and during the infusion.Platelet adhesiveness, as measured by a cellophane membrane test-cell system, was significantly diminished by PG...

journal_title：Journal of clinical pathology

authors： Howie PW,Calder AA,Forbes CD,Prentice CR

更新日期：1973-05-01 00:00:00

abstract：:Automation in clinical chemistry is a powerful tool. Like most innovations it is posing many questions as well as resolving some. Its use in population screening has led to questioning the validity of the old system of ;normal values' and to the search for better methods of indicating the significance of laboratory te...

journal_title：Journal of clinical pathology

authors： Wilson JM

更新日期：1973-08-01 00:00:00

abstract：:A biochemical typing method is described for Klebsiella pneumoniae (sensu lato) and Enterobacter aerogenes. The technique depends on differences in metabolism of five carbon substrates--glycerol, inositol, lactose, glucose, and xylose--at two concentrations. Reproducibility is satisfactory and is monitored by the inco...

journal_title：Journal of clinical pathology

authors： Barr JG,Hogg GM

更新日期：1979-09-01 00:00:00

abstract：AIMS:To test whether a hypoacidic environment may potentially "stress" Helicobacter pylori DNA, encouraging the emergence of strain variation. METHODS:This hypothesis was tested by inducing prolonged hypoacidity with omeprazole, a potent antisecretory drug. The genomic DNA of H pylori was studied by electrophoretic se...

journal_title：Journal of clinical pathology

authors： Fraser AG,Bickley J,Owen RJ,Pounder RE

更新日期：1992-12-01 00:00:00

abstract：AIMS:Evidence suggests that the presence of tumour necrosis is an adverse prognostic factor in renal cell carcinoma (RCC). However, it has also been shown that tumour regression, a microscopic feature associated with necrosis, may be a favourable short term prognostic factor in RCC. METHODS:Pathology reports of 253 RC...

journal_title：Journal of clinical pathology

authors： Foria V,Surendra T,Poller DN

更新日期：2005-01-01 00:00:00

abstract：AIMS:The development of a technique for simultaneous in situ hybridisation for native mRNA and conventional immunofluorescence for cytoplasmic antigens in routine pathology specimens. METHODS:Cocktails of synthetic deoxyoligonucleotides coding for immunoglobulin J chain and kappa light chain were 3' end labelled enzym...

journal_title：Journal of clinical pathology

authors： Harper SJ,Pringle JH,Gillies A,Allen AC,Layward L,Feehally J,Lauder I

更新日期：1992-02-01 00:00:00

abstract：:Normal haemoglobin is a tetramer molecule, consisting of two α and β haemoglobin chains. Haemoglobinopathies occur when abnormalities in these proteins are present. More than 1000 naturally occurring human haemoglobin variants with single amino acid substitution throughout the molecule have been identified and can be ...

journal_title：Journal of clinical pathology

authors： Ruetsch C,Raffort J,Panaia-Ferrari P,Deconde C,Caruba-Bafghi C,Naimi M,Kavafyan J,Suissa L,Chinetti G

更新日期：2019-07-01 00:00:00

abstract：AIMS:To evaluate and compare the long term prognostic value of the WHO classification and the computerised multivariate morphometrical D score in endometrial hyperplasia. To test the reproducibility of the D score in two different centres. METHODS:Histopathological WHO classification and computerised morphometrical an...

journal_title：Journal of clinical pathology

authors： Orbo A,Baak JP,Kleivan I,Lysne S,Prytz PS,Broeckaert MA,Slappendel A,Tichelaar HJ

更新日期：2000-09-01 00:00:00

abstract：AIMS:To study whether differences in eradication rates of antibiotics may be explained by differences in secretion of antibiotics in gastric juice. METHODS:A single intravenous dose of either ampicillin 500 mg, erythromycin 500 mg, or metronidazole 500 mg was administered to four healthy Helicobacter pylori negative v...

journal_title：Journal of clinical pathology

authors： van Zanten SJ,Goldie J,Hollingsworth J,Silletti C,Richardson H,Hunt RH

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:To investigate p53 and hepatoma-derived growth factor (HDGF) expression and their association with clinicopathological features of Ewing family tumour (EFT). EXPERIMENTAL DESIGN:A total of 108 cases of EFT were retrospectively analysed. p53 and HDGF expression were detected using immunohistochemistry, and the ...

journal_title：Journal of clinical pathology

authors： Yang Y,Zhen T,Zhang F,Dai S,Kang L,Liang Y,Xue L,Han A

更新日期：2014-03-01 00:00:00

abstract：:The T(4)-free thyroxine index was used as the thyroid function test of first choice in a district general hospital for one year. Ninety-two patients were assessed both initially and at follow up by a single physician. The index agreed with clinical assessment in 69 out of 74 patients in whom diagnosis was unequivocal....

journal_title：Journal of clinical pathology

authors： Howorth PJ,Ward RL

更新日期：1972-03-01 00:00:00

abstract：:The pathological findings of an intradural and extramedullary cyst in the mid cervical spinal canal are described in a 55 year old woman who presented with a short history of pain and paraesthesia of the right arm. Intradural well defined solitary cystic lesions in the spinal canal are uncommon, their pathogenesis is ...

journal_title：Journal of clinical pathology

authors： Wilkinson N,Reid H,Hughes D

更新日期：1992-11-01 00:00:00

abstract：:Veno-occlusive disease of the liver with clinical and pathological features similar to those of the condition occurring in the Caribbean is described in a young woman resident in Britain. The diagnosis was made from liver biopsies and hepatic venography and was confirmed at necropsy. Small amounts of pyrroliziding alk...

journal_title：Journal of clinical pathology

authors： McGee J,Patrick RS,Wood CB,Blumgart LH

更新日期：1976-09-01 00:00:00

abstract：:A technique is described whereby inclusion-bearing cells identified by light microscopy in stained smears of urinary sediment were reprocessed for examination in the electron microscope. The nuclei of the abnormal cells were found to contain numerous virus particles, 35 nm in diameter, which morphologically resembled ...

journal_title：Journal of clinical pathology

authors： Coleman DV,Russell WJ,Hodgson J,Pe T,Mowbray JF

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:HER2/neu (HER2) is a significant prognostic marker for breast carcinomas. Recently, new guidelines defining HER2 genetic heterogeneity (GH) were published by the College of American Pathologists. AIMS:To determine the prevalence of HER2 GH as defined in primary invasive breast carcinoma, to determine its re...

journal_title：Journal of clinical pathology

authors： Shafi H,Astvatsaturyan K,Chung F,Mirocha J,Schmidt M,Bose S

更新日期：2013-08-01 00:00:00

abstract：AIMS:Periductal angiogenesis in ductal carcinoma in situ is associated with an increased risk of subsequently developing a recurrence. This study aimed to (1) identify the relation between periductal and stromal vascularity and recurrence and (2) determine whether thymidine phosphorylase (TP) is associated with angioge...

journal_title：Journal of clinical pathology

authors： Teo NB,Shoker BS,Jarvis C,Sloane JP,Holcombe C

更新日期：2003-12-01 00:00:00

abstract：:Liver copper concentrations in percutaneous biopsy specimens were measured by neutron activation analysis and compared with histological staining for copper by rubeanic acid and rhodanine, and with copper-associated protein stained by orcein. Liver copper concentrations were elevated in 31 of 35 biopsies from patients...

journal_title：Journal of clinical pathology

authors： Jain S,Scheuer PJ,Archer B,Newman SP,Sherlock S

更新日期：1978-08-01 00:00:00

abstract：:Pre-mRNA splicing is an essential process in eukaryotic cells where the transcribed intronic sequences are removed, prior to translation into protein. PRPF31 is a ubiquitously expressed splicing factor, which aids in the assembly of the macromolecular spliceosome. Mutations in PRPF31 cause autosomal dominant retinitis...

journal_title：Journal of clinical pathology

authors： Rose AM,Luo R,Radia UK,Bhattacharya SS

更新日期：2017-09-01 00:00:00

abstract：AIMS:To develop a rapid, sensitive, and safe method for the analysis of von Willebrand factor (vWf) multimers in plasma or platelet lysates. METHOD:Analysis of vWf multimers was carried out by sodium dodecyl sulphate-agarose discontinuous gel electrophoresis followed by protein transfer to nitrocellulose membranes by ...

journal_title：Journal of clinical pathology

authors： Cumming AM,Wensley RT

更新日期：1993-05-01 00:00:00

abstract：:Chromosome studies were attempted on 97% of necropsies carried out in the Department of Histopathology of the Adelaide Children's Hospital over the four-year period ending May 1981. Results were obtained from 89% of necropsies of which 7.5% had major chromosome abnormalities. The chromosome results are analysed accord...

journal_title：Journal of clinical pathology

authors： Sutherland GR,Carter RF

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Subgroups of breast cancer that have an impaired response to endocrine treatment, despite hormone receptor positivity, are still poorly defined. Breast cancer can be subdivided according to standard pathological parameters including histological type, grade, and assessment of proliferation. These parameters ...

journal_title：Journal of clinical pathology

authors： Jirström K,Rydén L,Anagnostaki L,Nordenskjöld B,Stål O,Thorstenson S,Chebil G,Jönsson PE,Fernö M,Landberg G

更新日期：2005-11-01 00:00:00

abstract：:Immune and non-immune rubella sera were examined in the haemagglutination inhibition (HAI) test to evaluate the removal of lipoprotein non-specific inhibitors (NSI) of haemagglutination after kaolin and manganous chloride/heparin treatments. The sera were titrated fresh or after lipoprotein deterioration brought about...

journal_title：Journal of clinical pathology

authors： Shortridge KF

更新日期：1977-05-01 00:00:00

abstract：:A saccharogenic method is described for estimating amylase activity in human urine. Results accord with those reported elsewhere except that in this study the peak in the beta zone is a new finding. Comparison between normal and pathological urines suggests that the amylase activity of the beta peak is not of pancreat...

journal_title：Journal of clinical pathology

authors： Franzini C

更新日期：1965-09-01 00:00:00

abstract：:A 65-year-old woman with a history of a left heminephrectomy for renal carcinoma developed hypercalcaemia 11 years after the operation. The same kidney was found to contain a recurrent renal carcinoma. After the radical nephrectomy of the left kidney, hypercalcaemia remitted but reappeared 11 months later. The right k...

journal_title：Journal of clinical pathology

authors： Szwed JJ,Gott LJ,Lempke RE,Seo IS

更新日期：1979-03-01 00:00:00

abstract：:A case of abnormal chromatin clumping (ACC) which arose during the course of a myelodysplastic/myeloproliferative syndrome is described in a 61 year old woman who died of haemorrhage 43 months after diagnosis. Mature granulocytes exhibited the same nuclear abnormality described in other patients reported. Unusually, s...

journal_title：Journal of clinical pathology

authors： Gardais J

更新日期：1993-02-01 00:00:00

abstract：AIMS:To determine how epithelial and stromal thymidine phosphorylase expression affects angiogenesis, rapid tumour growth, and decreased apoptotic activity in cervical cancer at varying stages of progression. METHODS:Epithelial and stromal thymidine phosphorylase expression, the microvessel count (reflected by factor ...

journal_title：Journal of clinical pathology

authors： Fujiwaki R,Hata K,Iida K,Maede Y,Koike M,Miyazaki K

更新日期：1999-08-01 00:00:00